• Title/Summary/Keyword: MS-2 system

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Efficiency of Combined Action of Moxalactam and Fosfomycin Determined by MS-2 System Against Penicillin-resistant Staphylococcus aureus Isolates (MS-2 system을 이용한 황색포도구균에 대한 moxalactam과 fosfomycin의 병용효과 측정)

  • Park, Chan-Sok;Ahn, Tai-Hew
    • The Journal of the Korean Society for Microbiology
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    • v.21 no.3
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    • pp.381-385
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    • 1986
  • Twenty strains of penicillin(PC)-resistant Staphylococcus aureus ($MIC{\geqq}32U/ml$) were chosen randomly from recent isolates and submitted to the present experiment to see what effect the combined antibiotic action of moxalactam(MX) and fosfomycin(FM) would bring about on the cells, using MS-2 system. 1. The conventional agar dilution method and the rapid automatic MS-2 system were used in measuring the MICs of MX and FM against each strain and the comparison of the data obtained revealed no significant difference between the two methods in the titer and distribution of the MICs. 2. The automatic MS-2 system was, therefore, used alone in determining the combined growth inhibitory effect of MX and FM because of its more rapidness, and the obtained results were that most of the PC-resistant strains(16 out of 20, 80%) were synergistically inhibited by the two antibiotic combination while additive effect was observed in the remaining 4 strains(20%). 3. Thus, it is suggested that the growth of PC-resistant staphylococcal cells may be synergistically inhibited by MX and FM combination and the efficiency of two antibiotic action as well as MIC of single antibiotic may be more rapidly determined by the MS-2 system than by the conventional method.

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A Study on the dimensional model of the meridian system (경락시스템의 층차적 모형에 관한 고찰)

  • Choi, Hwan-soo
    • Journal of Acupuncture Research
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    • v.20 no.2
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    • pp.1-10
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    • 2003
  • Objective : It is limited to verify existence and a part of characteristic of MS(Meridian system) in modern MS hypothesis. Because it is that an object of scientific approach is to prove a structure of MS. Then according to DMMS, we will research on a subject of MSs rules. This is a paper on the investigation of DMMS in aspects of propriety and supplement. Results : DMMS is composed of organizational anatomy system, MS, signal system. This means that the contents of classic MS theory divide into three dimensions. It includes classic MS theory and explains modern MS hypothesis with DMMS. But is has two problems that one is the difference between the right side and the left in the same meridian and the other is a lack of dynamic idea(動態觀念). After apply this ti analysis system, it will be reasonable to DMMS. It indicates to use various ways of a science, especially, mathematics, system theory, information theory, control theory to supplement the DMMS. Conclusions : Although the scientific study of MS is stagnant, the approach of this DMMS will provide us with a new result of MS.

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Identification of Xanthium Sibiricum Components using LC-SPE-NMR-MS Hyphenated System

  • Sohn, Ji Soo;Jung, Youngae;Han, Ji Soo;Hwang, Geum-Sook
    • Journal of the Korean Magnetic Resonance Society
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    • v.22 no.2
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    • pp.26-33
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    • 2018
  • Xanthium sibiricum is used as a traditional folk medicine for the treatment of cancer, fever, headache, nasal sinusitis, and skin pruritus. This study aimed to identify components from Xanthium sibiricum extracts using an SPE-800MHz NMR-MS hyphenated system. The simultaneous acquisition of MS and NMR spectra from the same chromatographic peaks significantly increases the depth of information acquired for the compound and allows the elucidation of structures that would not be possible using MS or NMR data alone. LC -NMR analysis was conducted using a HPLC separation system coupled to 800 MHz spectrometer equipped with a cryoprobe, and a SPE unit was used to automatically trap chromatographic peaks using a HPLC pump. LC-MS analysis was conducted with a Q-TOF MS instrument using ESI ionization in the negative ion mode. Using the hyphenated analysis, several secondary metabolites were identified, such as 3',5'-O-dicaffeoylquinic acid, 1',5'-O-dicaffeoyl- quinic acid, and ethyl caffeate. These results demonstrate that the SPE-800MHz NMR-MS hyphenated system can be used to identify metabolites within natural products that have complex mixtures.

The Design and Implementation of the Mutual Message Processing between WME Module and MLME Module for Vehicle Communication Technology (차량 통신 기술을 위한 WME 모듈과 MLME 모듈 간의 상호 메시지 처리과정 설계 및 구현)

  • Jang, Chung Ryong;Lee, Dae Sik;Lee, Yong Kwon
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.9 no.2
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    • pp.63-71
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    • 2013
  • WAVE(Wireless Access for Vehicular Environment) System is a communication technology to monitor system failure and vehicle functions and management services to prevent possible incidents of driving a vehicle. In this paper, we have designed and implemented the mutual message processing through parameter between WME management module that manages WAVE system and MLME that manages the upper layer MAC(Media Access Control) module. Also, in order to verify the validity, we have carried out experiments to compare the speed of data processing by dividing data of 1Mbyte, 2Mbyte, 3Mbyte into the packets of 2KByte and 4KByte. Experiments data processing speed of 2KByte packet were shown about 173.62ms in 1MByte, 2MByte about 352.61ms, 3MByte about 550.13ms and, data processing speed of 4KByte packet, 1MByte approximately 87.56ms, 2MByte about 177.94ms, 3MByte about 277.18ms. Therefore, in WAVE system, the mutual messages processing through the parameters between WME and MLME module can be utilized in the various service of ITS(Intelligent Transportation Systems) depending on the speed of data processing.

The Design and Implementation of a Method for Identifying RCP in the Vehicle Tracking System (차량 추적 시스템에서 RCP를 식별하기 위한 방법 설계 및 구현)

  • Lee, Yongkwon;Jang, Chungryong;Lee, Daesik
    • Journal of Korea Society of Digital Industry and Information Management
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    • v.12 no.2
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    • pp.15-24
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    • 2016
  • GPS(Global Positioning System) location tracking is a method for taking the precise coordinates after the coordinates are obtained by a GPS receiver, and displaying them on the map. In this paper with WAVE(Wireless Access for Vehicular Environment) simulation, we show that various services such as vehicle tracking service, real-time road conditions service and logistics can go tracking service, control and operation services according to the vehicle position and the traveling direction by using the GPS position data. A vehicle tracking system using GPS is automatically able to manage multiple RCP when exchanging data between RMA and the RCP, and it provides rapid requests and responses. To verify that multiple sessions between RMA and RM, as well as multiple sessions between RMA and RCP are able to be implemented, we take RMA as a RCP application on an OBU, until the RMA is receiving data response from corresponding RM. As a result of this experiment, we show that the response speeds of single session between RMA and RM using 1, 2, 3, and 4 kbyte unit data are similar, 62.32ms, 62.65ms, 63.02ms, and 63.48ms, respectively. Likewise, those of 128 muliple sessions using 1, 2, 3, and 4 kbyte unit data are not much more time difference, 298.08ms, 302.21ms, 322.85ms, and 329.62ms, respectively.

Inactivation of Escherichia coli and MS2 coliphage by Cu(II)-activated peroxomonosulfate in natural water

  • Kim, Hyung-Eun;Lee, Hye-Jin;Kim, Min Sik;Choi, Joon-Young;Lee, Changha
    • Membrane and Water Treatment
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    • v.10 no.3
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    • pp.231-237
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    • 2019
  • Peroxymonosulfate (PMS) in combination with Cu(II) was examined to inactivate E. coli and MS2 coliphage in natural water. The combined system (i.e., the Cu(II)/PMS system) caused a synergistic inactivation of E. coli and MS2, in contrast with either Cu(II) or PMS alone. Increasing the concentration of PMS enhanced the inactivation of E. coli and MS2, but after a certain point, it decreased the efficacy of the microbial inactivation. In the Cu(II)/PMS system, adding reactive oxidant scavengers marginally affected the E. coli inactivation, but the inhibitory effects of copper-chelating agents were significant. Fluorescent assays indicated that the Cu(II)/PMS system greatly increased the level of reactive oxidants inside the E. coli cells. The sequential addition of Cu(II) and PMS inactivated more E. coli than did adding the two simultaneously; in particular, the inactivation efficacy was much higher when Cu(II) was added first. The observations from the study collectively showed that the microbial inactivation by the Cu(II)/PMS system could be attributed to the toxicity of Cu(I) as well as the intracellular oxidative stress induced by Cu(III) or radical species.

Development and Performance Experiment of Iso-tensioning System using Electrical Resistance Loadcell (전기저항식 로드셀을 이용한 균등긴장시스템 개발 및 성능실험)

  • Park, Won-Tae;Chun, Kyoung-Sik
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.2
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    • pp.220-226
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    • 2016
  • Because MS(Multi-Strand) cables consist of many strands, a jacking force is applied to each strand one by one for cable construction. All strands should have an equal tensile force when the last one is wedged. This is the core technology for MS iso-tensioning. In this study, a new MS cable iso-tensioning system was developed for controlling and jacking the high-strength strands, with an ultimate tensile strength of 2,200MPa, for a stay cable of extra-dosed/cable-stayed bridges. The newly developed iso-tensioning system consists of electrical resistance load cells, hydraulic jacking devices, hydraulic pumps, and integrated controllers. Moreover, it is embedded with an algorithm that can control and predict the variations in tensile forces of the Master and Slave strands in real time. Actual experiments were carried out to verify the function and performance of the newly developed system. This system was applied successfully to the stay cable construction of 2nd Tae-in extra-dosed bridge in Gwangyang.

Mass Fragmentation Patterns as Fingerprints for Positive Identification of Polyphenolic Compounds in a Crude Extract

  • Manshoor, Nurhuda;Weber, Jean-Frederic F.
    • Mass Spectrometry Letters
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    • v.6 no.4
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    • pp.105-111
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    • 2015
  • Sixteen compounds of Neobalanocarpus heimii were successfully identified directly from their plant extract using a triple quadrupole LC-MS/MS system. In order to fulfil the objectives of this work, a series of stilbene oligomers of various degrees of condensation were isolated and their structure are characterized. Out of these, four are resveratrol dimers, three trimers, and nine tetramers. The isolation process was done on a fully automated semi-preparative HPLC system. Their structures were elucidated on the basis of 1D- and 2D-NMR as well as MS data. The mass fragmentation patterns of the compounds were recorded and a retrievable in-house library was built to keep the data. In order to demonstrate the potential of this approach, the polyphenolic crude extract was analysed with the LC-MS/MS system and the MS/MS spectra extracted for each chromatographic peak of interest. The fragmentation patterns were compared with those of anticipated pure compounds that were previously recorded. All compounds were successfully identified. It is therefore believed that the LC-MS/MS potential for dereplication of structurally similar compounds in a crude mixture was thus firmly established.

Characteristics in Heart Rate Variability associated with Early Life Stress in Patients with Major Depressive Disorder (주요우울장애 환자에서 생애초기스트레스와 연관된 심박변이도의 특성)

  • Lee, Chiheon;Kim, Min-Kyeong;Choi, Sun-Woo;Park, Hae-in;Seok, Jeong-Ho
    • Mood & Emotion
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    • v.15 no.3
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    • pp.117-122
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    • 2017
  • Objectives : Early life stress (ELS) may have impact on functions of the autonomic nervous system. Heart rate variability (HRV) is a reliable psychophysiological marker for functions of the autonomic nervous system. The purpose of this study was to investigate characteristics of HRV associated with ELS in patients with major depressive disorder (MDD). Methods : We compared HRV measures of MDD patients with ELS and without ELS in a 5-minute resting-state electrocardiogram recoding. Forty subjects participated in the study (25 with ELS, 15 without ELS). The Mann-Whitney test was conducted to identify group differences. Results : We found significant group differences in standard deviation of the NN interval (SDNN) and total power (TP). SDNN was lower in the ELS group (M=38.80 ms, SD=13.05 ms) than in the Non-ELS group (M=53.53 ms, SD=19.47 ms). TP was lower in the ELS group ($M=7.07ms^2$, $SD=0.69ms^2$) than in the Non-ELS group ($M=7.72ms^2$, $SD=0.77ms^2$). Conclusion : ELS may have a negative impact on the autonomic nervous system function in patients with MDD. ELS and dysfunction of autonomic nervous system should be considered in treatment for patients with MDD.

Determination of heavy metals in mainstream smoke by ORS-ICP-MS (ORS-ICP-MS를 이용한 담배 연기의 중금속 성분 분석)

  • Cho, Sung-Eel;Ji, Sang-Un;Hwang, Keon-Joong
    • Journal of the Korean Society of Tobacco Science
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    • v.30 no.1
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    • pp.25-32
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    • 2008
  • In this study, we compared three different pretreatment methods, such as block digestion, microwave digestion and solvent injection, coupled with Octopole Reaction System(ORS)-ICP-MS was used for the quantification of heavy metals in mainstream smoke of 2R4F reference cigarette, and then evaluated those efficiencies in the recovery, repeatability and reproducibility. In all methods, volatile heavy metals, As, showed the highest CV value, and Cd showed the lowest one. However, the solvent injection method showed the most stable recovery rate and CV value of 2.36 %. This method showed also advantages in time-consuming and compatibility with ICP-MS system. This results demonstrate that solvent injection method can be recommended as a superior pretreatment procedure to be able to reduce contaminants and spectral interference as well as loss of the elements interested.