• 대한미생물학회지
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• 제21권3호
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• pp.381-385
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• 1986

Twenty strains of penicillin(PC)-resistant Staphylococcus aureus ($MIC{\geqq}32U/ml$) were chosen randomly from recent isolates and submitted to the present experiment to see what effect the combined antibiotic action of moxalactam(MX) and fosfomycin(FM) would bring about on the cells, using MS-2 system. 1. The conventional agar dilution method and the rapid automatic MS-2 system were used in measuring the MICs of MX and FM against each strain and the comparison of the data obtained revealed no significant difference between the two methods in the titer and distribution of the MICs. 2. The automatic MS-2 system was, therefore, used alone in determining the combined growth inhibitory effect of MX and FM because of its more rapidness, and the obtained results were that most of the PC-resistant strains(16 out of 20, 80%) were synergistically inhibited by the two antibiotic combination while additive effect was observed in the remaining 4 strains(20%). 3. Thus, it is suggested that the growth of PC-resistant staphylococcal cells may be synergistically inhibited by MX and FM combination and the efficiency of two antibiotic action as well as MIC of single antibiotic may be more rapidly determined by the MS-2 system than by the conventional method.

• Journal of Acupuncture Research
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• 제20권2호
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• pp.1-10
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• 2003

Objective : It is limited to verify existence and a part of characteristic of MS(Meridian system) in modern MS hypothesis. Because it is that an object of scientific approach is to prove a structure of MS. Then according to DMMS, we will research on a subject of MSs rules. This is a paper on the investigation of DMMS in aspects of propriety and supplement. Results : DMMS is composed of organizational anatomy system, MS, signal system. This means that the contents of classic MS theory divide into three dimensions. It includes classic MS theory and explains modern MS hypothesis with DMMS. But is has two problems that one is the difference between the right side and the left in the same meridian and the other is a lack of dynamic idea(動態觀念). After apply this ti analysis system, it will be reasonable to DMMS. It indicates to use various ways of a science, especially, mathematics, system theory, information theory, control theory to supplement the DMMS. Conclusions : Although the scientific study of MS is stagnant, the approach of this DMMS will provide us with a new result of MS.

• 한국자기공명학회논문지
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• 제22권2호
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• pp.26-33
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• 2018

Xanthium sibiricum is used as a traditional folk medicine for the treatment of cancer, fever, headache, nasal sinusitis, and skin pruritus. This study aimed to identify components from Xanthium sibiricum extracts using an SPE-800MHz NMR-MS hyphenated system. The simultaneous acquisition of MS and NMR spectra from the same chromatographic peaks significantly increases the depth of information acquired for the compound and allows the elucidation of structures that would not be possible using MS or NMR data alone. LC -NMR analysis was conducted using a HPLC separation system coupled to 800 MHz spectrometer equipped with a cryoprobe, and a SPE unit was used to automatically trap chromatographic peaks using a HPLC pump. LC-MS analysis was conducted with a Q-TOF MS instrument using ESI ionization in the negative ion mode. Using the hyphenated analysis, several secondary metabolites were identified, such as 3',5'-O-dicaffeoylquinic acid, 1',5'-O-dicaffeoyl- quinic acid, and ethyl caffeate. These results demonstrate that the SPE-800MHz NMR-MS hyphenated system can be used to identify metabolites within natural products that have complex mixtures.

• 디지털산업정보학회논문지
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• 제9권2호
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• pp.63-71
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• 2013

WAVE(Wireless Access for Vehicular Environment) System is a communication technology to monitor system failure and vehicle functions and management services to prevent possible incidents of driving a vehicle. In this paper, we have designed and implemented the mutual message processing through parameter between WME management module that manages WAVE system and MLME that manages the upper layer MAC(Media Access Control) module. Also, in order to verify the validity, we have carried out experiments to compare the speed of data processing by dividing data of 1Mbyte, 2Mbyte, 3Mbyte into the packets of 2KByte and 4KByte. Experiments data processing speed of 2KByte packet were shown about 173.62ms in 1MByte, 2MByte about 352.61ms, 3MByte about 550.13ms and, data processing speed of 4KByte packet, 1MByte approximately 87.56ms, 2MByte about 177.94ms, 3MByte about 277.18ms. Therefore, in WAVE system, the mutual messages processing through the parameters between WME and MLME module can be utilized in the various service of ITS(Intelligent Transportation Systems) depending on the speed of data processing.

• 디지털산업정보학회논문지
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• 제12권2호
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• pp.15-24
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• 2016

GPS(Global Positioning System) location tracking is a method for taking the precise coordinates after the coordinates are obtained by a GPS receiver, and displaying them on the map. In this paper with WAVE(Wireless Access for Vehicular Environment) simulation, we show that various services such as vehicle tracking service, real-time road conditions service and logistics can go tracking service, control and operation services according to the vehicle position and the traveling direction by using the GPS position data. A vehicle tracking system using GPS is automatically able to manage multiple RCP when exchanging data between RMA and the RCP, and it provides rapid requests and responses. To verify that multiple sessions between RMA and RM, as well as multiple sessions between RMA and RCP are able to be implemented, we take RMA as a RCP application on an OBU, until the RMA is receiving data response from corresponding RM. As a result of this experiment, we show that the response speeds of single session between RMA and RM using 1, 2, 3, and 4 kbyte unit data are similar, 62.32ms, 62.65ms, 63.02ms, and 63.48ms, respectively. Likewise, those of 128 muliple sessions using 1, 2, 3, and 4 kbyte unit data are not much more time difference, 298.08ms, 302.21ms, 322.85ms, and 329.62ms, respectively.

• Membrane and Water Treatment
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• 제10권3호
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• pp.231-237
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• 2019

Peroxymonosulfate (PMS) in combination with Cu(II) was examined to inactivate E. coli and MS2 coliphage in natural water. The combined system (i.e., the Cu(II)/PMS system) caused a synergistic inactivation of E. coli and MS2, in contrast with either Cu(II) or PMS alone. Increasing the concentration of PMS enhanced the inactivation of E. coli and MS2, but after a certain point, it decreased the efficacy of the microbial inactivation. In the Cu(II)/PMS system, adding reactive oxidant scavengers marginally affected the E. coli inactivation, but the inhibitory effects of copper-chelating agents were significant. Fluorescent assays indicated that the Cu(II)/PMS system greatly increased the level of reactive oxidants inside the E. coli cells. The sequential addition of Cu(II) and PMS inactivated more E. coli than did adding the two simultaneously; in particular, the inactivation efficacy was much higher when Cu(II) was added first. The observations from the study collectively showed that the microbial inactivation by the Cu(II)/PMS system could be attributed to the toxicity of Cu(I) as well as the intracellular oxidative stress induced by Cu(III) or radical species.

• 한국산학기술학회논문지
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• 제17권2호
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• pp.220-226
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• 2016

MS(Multi-Strand) 케이블은 여러 개의 강연선으로 이루어져있어, 케이블 시공시 각 강연선을 차례대로 개별적으로 긴장한다. 그리고 마지막 강연선이 정착되었을 때, 모든 강연선에 동일한 장력이 도입되어야하며, 이것이 MS 균등긴장의 핵심기술이다. 본 연구에서는 엑스트라도즈(Extradosed)교 및 사장교의 사재케이블(Stay Cable)에 적용되는 2,200MPa 초고강도 강연선들을 균등하게 긴장, 제어할 수 있는 MS 케이블 균등긴장시스템을 개발하였다. 개발한 균등긴장시스템은 전기저항식 로드셀, 유압잭, 유압펌프 그리고 통합제어기로 구성되며, Master 강연선과 Slave 강연선의 장력변화를 실시간으로 예측하며 제어하는 알고리즘을 탑재하였다. 개발시스템의 기능과 성능을 검증하기 위해 균등긴장 실험을 수행한 후, 광양 태인2교(ED교)의 사재케이블 가설긴장에 성공적으로 적용하였다.

• Mass Spectrometry Letters
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• 제6권4호
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• pp.105-111
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• 2015

Sixteen compounds of Neobalanocarpus heimii were successfully identified directly from their plant extract using a triple quadrupole LC-MS/MS system. In order to fulfil the objectives of this work, a series of stilbene oligomers of various degrees of condensation were isolated and their structure are characterized. Out of these, four are resveratrol dimers, three trimers, and nine tetramers. The isolation process was done on a fully automated semi-preparative HPLC system. Their structures were elucidated on the basis of 1D- and 2D-NMR as well as MS data. The mass fragmentation patterns of the compounds were recorded and a retrievable in-house library was built to keep the data. In order to demonstrate the potential of this approach, the polyphenolic crude extract was analysed with the LC-MS/MS system and the MS/MS spectra extracted for each chromatographic peak of interest. The fragmentation patterns were compared with those of anticipated pure compounds that were previously recorded. All compounds were successfully identified. It is therefore believed that the LC-MS/MS potential for dereplication of structurally similar compounds in a crude mixture was thus firmly established.

• 우울조울병
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• 제15권3호
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• pp.117-122
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• 2017

Objectives : Early life stress (ELS) may have impact on functions of the autonomic nervous system. Heart rate variability (HRV) is a reliable psychophysiological marker for functions of the autonomic nervous system. The purpose of this study was to investigate characteristics of HRV associated with ELS in patients with major depressive disorder (MDD). Methods : We compared HRV measures of MDD patients with ELS and without ELS in a 5-minute resting-state electrocardiogram recoding. Forty subjects participated in the study (25 with ELS, 15 without ELS). The Mann-Whitney test was conducted to identify group differences. Results : We found significant group differences in standard deviation of the NN interval (SDNN) and total power (TP). SDNN was lower in the ELS group (M=38.80 ms, SD=13.05 ms) than in the Non-ELS group (M=53.53 ms, SD=19.47 ms). TP was lower in the ELS group ($M=7.07ms^2$, $SD=0.69ms^2$) than in the Non-ELS group ($M=7.72ms^2$, $SD=0.77ms^2$). Conclusion : ELS may have a negative impact on the autonomic nervous system function in patients with MDD. ELS and dysfunction of autonomic nervous system should be considered in treatment for patients with MDD.

• 한국연초학회지
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• 제30권1호
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• pp.25-32
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• 2008

In this study, we compared three different pretreatment methods, such as block digestion, microwave digestion and solvent injection, coupled with Octopole Reaction System(ORS)-ICP-MS was used for the quantification of heavy metals in mainstream smoke of 2R4F reference cigarette, and then evaluated those efficiencies in the recovery, repeatability and reproducibility. In all methods, volatile heavy metals, As, showed the highest CV value, and Cd showed the lowest one. However, the solvent injection method showed the most stable recovery rate and CV value of 2.36 %. This method showed also advantages in time-consuming and compatibility with ICP-MS system. This results demonstrate that solvent injection method can be recommended as a superior pretreatment procedure to be able to reduce contaminants and spectral interference as well as loss of the elements interested.