• Investigative Magnetic Resonance Imaging
• /
• 제20권3호
• /
• pp.152-157
• /
• 2016

Purpose: Operating room management is the serious and complex task for hospital managers and the common approach is to develop relevant standard operational procedures. From patient and staff safety perspective, operating room management should be well-studied and hospital should identify and address any potential risks. Simultaneous usage of different imaging and less-invasive treatment technologies demands strong management control. Materials and Methods: We have formed the multidisciplinary expert panel (surgeons, anesthesiologists, radiologists, healthcare managers etc.) for hybrid theater management standard operational procedure development. On the first stage the general concept of hybrid room design and patient routing was developed. The second stage included the technical details discussion. For patient safety improvement we modified the Surgical Safety Check-list in accordance with potential MRI-related safety challenges and concerns. Results: WHO Surgical Safety Checklist is a simple and easy-to use tool which includes three blocks of question (grouped by the surgery process). We have developed two additional blocks of questions for the intraoperative magnetic resonance investigation. It is very important to have a special detailed routing with a strong control of ferromagnetic devices and anesthesiology care. Conclusion: High-energy MRI (1.5-3.0T) is characterized by potential influence on patient and staff safety in case of hybrid surgery. It is obvious to have a strong managerial control of ferromagnetic devices and anesthesiology care. Surgical Safety Checklist is the validated tool for improving patient safety. Modification and customization of this check-list potentially provides the opportunity for surgery processes improving.

• Investigative Magnetic Resonance Imaging
• /
• 제23권1호
• /
• pp.34-37
• /
• 2019

Gadolinium contrast agents (CAs) are integral components of clinical magnetic resonance imaging (MRI). However, safety concerns have arisen regarding the use of gadolinium CAs, due to their association with nephrogenic systemic fibrosis (NSF). Furthermore, recently the long-term retention of $Gd^{3+}-based$ CAs in brains patients with normal renal function raised another possible safety issue. The safety concerns of $Gd^{3+}-based$ CAs have been based on the ligand structure of $Gd^{3+}-based$ CAs, and findings that $Gd^{3+}-based$ CAs with linear ligand structures showed much higher incidences of NSF and brain retention of CAs than $Gd^{3+}-based$ CAs with macrocyclic ligand structure. In the current study, we report the in vivo biodistribution profile of a new highly stable multifunctional $Gd^{3+}-based$ CA, with macrocyclic ligand structure (HNP-2006). MR imaging using HNP-2006 demonstrated a significant contrast enhancement in many different organs. Furthermore, the contrast enhanced tumor imaging using HNP-2006 confirmed that this new macrocyclic CA can be used for detecting tumor in the central nervous system. Therefore, this new multifunctional HNP-2006 with macrocyclic ligand structure shows great promise for whole-body clinical application.

• Korean Journal of Radiology
• /
• 제19권6호
• /
• pp.1053-1065
• /
• 2018

Objective: To evaluate the clinical impact of using registration software for ablative margin assessment on pre-radiofrequency ablation (RFA) magnetic resonance imaging (MRI) and post-RFA computed tomography (CT) compared with the conventional side-by-side MR-CT visual comparison. Materials and Methods: In this Institutional Review Board-approved prospective study, 68 patients with 88 hepatocellulcar carcinomas (HCCs) who had undergone pre-RFA MRI were enrolled. Informed consent was obtained from all patients. Pre-RFA MRI and post-RFA CT images were analyzed to evaluate the presence of a sufficient safety margin (${\geq}3mm$) in two separate sessions using either side-by-side visual comparison or non-rigid registration software. Patients with an insufficient ablative margin on either one or both methods underwent additional treatment depending on the technical feasibility and patient's condition. Then, ablative margins were re-assessed using both methods. Local tumor progression (LTP) rates were compared between the sufficient and insufficient margin groups in each method. Results: The two methods showed 14.8% (13/88) discordance in estimating sufficient ablative margins. On registration software-assisted inspection, patients with insufficient ablative margins showed a significantly higher 5-year LTP rate than those with sufficient ablative margins (66.7% vs. 27.0%, p = 0.004). However, classification by visual inspection alone did not reveal a significant difference in 5-year LTP between the two groups (28.6% vs. 30.5%, p = 0.79). Conclusion: Registration software provided better ablative margin assessment than did visual inspection in patients with HCCs who had undergone pre-RFA MRI and post-RFA CT for prediction of LTP after RFA and may provide more precise risk stratification of those who are treated with RFA.

• 대한자기공명의과학회:학술대회논문집
• /
• 대한자기공명의과학회.한국자기공명학회 2005년도 공동학술대회
• /
• pp.77-78
• /
• 2005

A specific FUS-MRI platform was designed for breast cancer treatment. phased array technologies, sideways FUS transmission, and spatio-temporal temperature control in the complete region of interest, were combined for a novel therapy approach with enhanced safety and afficacy. A phase I clinical trial will start soon.

• 대한의용생체공학회:의공학회지
• /
• 제25권3호
• /
• pp.183-188
• /
• 2004

Magnetic resonance current density imaging (MRCDI) is a useful method for measuring electrical current density distribution inside an object. To avoid object rotations during the conventional MRCDI scans, we have reconstructed current density component images by applying a spatial filter to the magnetic field data measured both inside and outside the object. To measure the magnetic field outside the object with MRI, we immersed the object in a water tank. To evaluate accuracy of the current density imaging, we have made a conductivity phantom with a corresponding finite element method model. We have compared the experimentally obtained current density images with the ones calculated by the finite element method. The average errors of the reconstructed current density images were 6.6 ∼ 45.4 ％ when the injected currents were 1 ∼ 24 mA. We expect that the current density component imaging technique can be used in diverse biomedical applications such as electrical therapy system developments and biological electrical safety analysis.

• 대한안전경영과학회지
• /
• 제13권2호
• /
• pp.243-249
• /
• 2011

The purpose of the study was to improve of performance for Magnetic Resonance Imaging (MRI) examination in the department of radiology. It was performed DMAIC (Define, Measure, Analyze, Improve, and Control). In the stage of definition, The fifth kinds of CTQ (critical to quality) by the kindness, the waiting time, the examination explanation, the waiting time and the waiting environment were selected by voice of customer. In the stage of measurement, the performed examinations and the reservation waiting time were measured each 1.77 and 1.69 sigma. In the stage of analysis, the potential key causes were determined the limited working hours and the difference of examination time of various entries. In the stage of improvement, MRI were performed with the operating system of 24 hours examination and the optimization of the difference of examination time by among of 30 minutes, 40 minutes, 50 minutes. Finally, the number of examinations and reserved waiting days were measured by each 3.17 and 1.71 sigma in the control stage.

• 한국전문물리치료학회지
• /
• 제22권2호
• /
• pp.70-80
• /
• 2015

The spinal cord is highly complex, consisting of a specialized neural network that comprised both neuronal and non-neuronal cells. Any kind of injury and/or insult to the spinal cord leads to a series of damaging events resulting in motor and/or sensory deficits below the level of injury. As a result, muscle paralysis (or paresis) leading to muscle atrophy or shrinking of the muscle along with changes in muscle fiber type, and contractile properties have been observed. Traditionally, histology had been used as a gold standard to characterize spinal cord injury (SCI)-induced adaptation in spinal cord and skeletal muscle. However, histology measurements is invasive and cannot be used for longitudinal analysis. Therefore, the use of conventional magnetic resonance imaging (MRI) is promoted to be used as an alternative non-invasive method, which allows the repeated measurements over time and secures the safety against radiation by using radiofrequency pulse. Currently, many of pathological changes and adaptations occurring after SCI can be measured by MRI methods, specifically 3-dimensional MRI with the advanced diffusion tensor imaging technique. Both techniques have shown to be sensitive in measuring morphological and structural changes in skeletal muscle and the spinal cord.

• 대한방사선기술학회지:방사선기술과학
• /
• 제46권2호
• /
• pp.115-122
• /
• 2023

The purpose of this study was to examine the association between the shapes and colors of emergency exit symbols, magnetic field warning symbols, and radiation zone symbols used in hospitals for staff and patient safety and their effects on cognitive memory. The hippocampal region's signal intensity(SI) was analyzed using fMRI. The Symbol 2 (1.75±0.54) with a green background had the highest signal intensity (SI) for emergency exits, according to the findings. The black symbol 2 (1.60±0.51) with a yellow background had the highest signal intensity (SI) for the magnetic field warning symbol, followed by the black symbol 1 (1.59±0.65) with an orange background. The black symbol 2 (1.59±0.59) with a yellow background and the black symbol 3 (1.58±0.52) with an orange background had the low signal intensity with slight differences as for the radiation zone symbols. In conclusion, it was determined that the signal intensity of the black symbol with a yellow background was the highest in the magnetic field area and radiation area. This implies that symbols with a high signal intensity (SI) must be utilized intensively. To ensure that the correct meaning of the symbols is communicated in the future, they must also be utilized regularly and continually in disaster safety education.

• 한국방사선학회논문지
• /
• 제11권3호
• /
• pp.139-146
• /
• 2017

Brain MRI 검사에서는 영상을 얻기 위해 RF Pulse를 인체에 조사하게 되는데 이때 조사된 RF Pulse 에너지의 상당부분은 우리 몸에 그대로 흡수되게 되고 이로 인해 인체의 온도가 상승하게 되는데 노출 정도에 따라 인체에 영향을 주게 된다. 동일한 RF Pulse 에너지를 주었더라도 인체에 금속이 삽입되었다면 금속으로 인해 인체의 전도도가 상당히 증가하기 때문에 SAR값이 증가하고 체온도 역시 상승할 것이다. 따라서 치아임플란트를 했을 때와 하지 않았을 때 인체의 머리에 나타나는 SAR값의 변화와 인체의 온도변화는 차이가 있지 않을까라는 의문으로 이번 연구를 시작하게 되었다. 실험은 3.0 Tesla MRI장비에서 발생되는 128MHz RF Pulse 주파수대에서 치아임플란트의 사용 유무에 따른 인체가 받는 SAR와 체온의 변화를 XFDTD 프로그램을 사용하여 인체두부 모델과 치아임플란트 모델을 활성화시켜 실험하였다. MRI장비에서 치아임플란트로 인해 인체두부 모델에 흡수되는 SAR의 평균값과 체온 상승을 살펴 본 결과 모두 증가하고 있음을 알 수 있다. 또한 계산 결과 평균 최대 SAR값과 뇌 부분의 최대 온도 상승이 국제 안전 기준치 이하로 나타났으나, 치아임플란트의 개수 증가에 따라 값이 변할 수 있으므로 그 영향을 간과할 수 없으며, 향후 과제로 치아임플란트 개수와 체적의 증가와 치아임플란트 재질에 따른 SAR, 온도 상승 시뮬레이션이 필요하다.

• Restorative Dentistry and Endodontics
• /
• 제43권4호
• /
• pp.39.1-39.20
• /
• 2018

Magnetic resonance imaging (MRI) is an advanced diagnostic tool used in both medicine and dentistry. Since it functions based on a strong uniform static magnetic field and radiofrequency pulses, it is advantageous over imaging techniques that rely on ionizing radiation. Unfortunately, the magnetic field and radiofrequency pulses generated within the magnetic resonance imager interact unfavorably with dental materials that have magnetic properties. This leads to unwanted effects such as artifact formation, heat generation, and mechanical displacement. These are a potential source of damage to the oral tissue surrounding the affected dental materials. This review aims to compile, based on the current available evidence, recommendations for dentists and radiologists regarding the safety and appropriate management of dental materials during MRI in patients with orthodontic appliances, maxillofacial prostheses, dental implants, direct and indirect restorative materials, and endodontic materials.