• Investigative Magnetic Resonance Imaging
• /
• v.14 no.1
• /
• pp.56-63
• /
• 2010

Purpose : DIR image is relatively free from susceptibility artifacts therefore, DIR image can make it possible to reliably measure cortical thickness/volume. One drawback of the DIR acquisition is the long scan time to acquire the fully sampled 3D data set. To solve this problem, we applied a parallel imaging method (GRAPPA) and verify the reliability of using the volumetric study. Materials and methods : Six healthy volunteers (3 males and 3 females; age $25.33{\pm}2.25$ years) underwent MRI using the 3D DIR sequence at a 3.0T Siemens Tim Trio MRI scanner. GRAPPA simulation was performed from the fully sampled data set for reduction factor 2. Data reconstruction was performed using MATLAB R2009b. Freesurfer v.4.3.0 was used to evaluate the cortical thickness of the entire brain, and to extract white matter information from the DIR image, Analyze 9.0 was used. The global cortical thickness estimated from the reconstructed image was compared with reference image by using a T-test in SPSS. Results : Although reduced SNR and blurring are observed from the reconstructed image, in terms of segmentation the effect was not so significant. The volumetric result was validated that there were no significant differences in many cortical regions. Conclusion : This study was performed with DIR image for a volumetric MRI study. To solve the long scan time of 3D DIR imaging, we applied GRAPPA algorithm. According to the results, fast imaging can be done with reduction factor 2 with little loss of image quality at 3.0T.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.11
• /
• pp.5005-5011
• /
• 2011

The purpose of this work is to know the validity of a new stimulation method in cognitive functional imaging using custom-designed images correspond to words or syllables improving the shortcomings of existing method using text. From March 2011 to May five Subjects in need of language related functional MRI scanning were selected and both of text stimulating method and image stimulating method sacanning were carried out three times each. Using 3.0T Philps MRI machine and Invivo Co's Eloquence system, data acquisition was performed with EPI-BOLD technique. Post processing was performed with SPM 99 while the activated signals were determined within 95 percent confidence level.The number of activation clusters and the activation ratio inside ROI were compared. As as result, all of the subject showed activation inside Broca area but it did not have statistical significance. In conclusion, the image sitimulation method has potential because image itself is a common means of recognition and it can be recognised easily even if there language barrier. This stimulation method can be applied to replacing the exising scanning method especially in the elderly, infants, foerigners who may not fully understand about the examination.

• Journal of the Institute of Electronics Engineers of Korea SC
• /
• v.37 no.5
• /
• pp.56-62
• /
• 2000

In this paper, an automatic extraction of the blood flow contour from cardiac MRI is proposed. By using the GVF snake which has wider capture range than the conventional snake, and by automatically generating the initial points along the outside of the contour of the zero GVF field in the edge image of the cardiac MRI, the blood flow contour can be automatically extracted, even when the contours have boundary concavities due to the papillary muscles, without any manual initialization of the experts. Experiments are conducted on the various real cardiac MRIs including noise and papillary muscles, and the proposed method is proved to be efficient in automatic extraction of the blood contours even if they have the boundary concavities.

• The Journal of Churna Manual Medicine for Spine and Nerves
• /
• v.5 no.1
• /
• pp.101-110
• /
• 2010

Objectives: The propose of this study is to find out the clinical application of conservative treatment to 3 patients who has Disc Extrusion on L-spine MRI Methods: We examined 3 patients with Lumbar Intervertebral Disc Herniation (HIVD of L-spine) with Disc Extrusion who showed changes on MRI images before/after the treatment among HIVD of L-spine patients who visited Jaseng Hospital of Oriental Medicine. Results: In this study, the first MRI examination of HIVD of L-spine patients was performed at the first visit and re-examination of MRI was done after the treatment. In each case, the size of the extruded disc was considerably reduced in MRI image. Low back and leg pain was also reduced significantly after conervative oriental medical treatment. Conclusions: Conservative oriental medical treatment can be effective for improving symptoms of HIVD, decreasing pain, also decreasing the volume of herniated disc.

• Proceedings of the KOSOMBE Conference
• /
• v.1996 no.05
• /
• pp.139-142
• /
• 1996

A remotly controlled interactive magnetic resonance imaging (MRI) has been tried using the World Wide Web. For this purpose, an HTTP server is developed on the host computer of the MRI system. Video and audio conferencing capability is also included for the experiment. Using the developed system, MRI imaging has been successfully carried out at the Signal Processing Lab in the Kwangwoon University with the remote MRI system located at the Medical Image Research Center in the KAIST in Daejon.

• Investigative Magnetic Resonance Imaging
• /
• v.24 no.3
• /
• pp.154-161
• /
• 2020

Purpose: A CT angiography spot sign (CTA-spot) is a significant predictor of the early expansion of an intracerebral hemorrhage (ICH-Ex). Dynamic-susceptibility-contrast magnetic resonance imaging (DSC-MRI) can track the real-time leaking of contrast agents. It may be able to indicate active bleeding, like a CTA-spot. Materials and Methods: From September 2014 to February 2017, we did non-contrast CT, CTA, and DSC-MRI examinations of seven patients with acute ICH. We investigated the time from symptom onset to the first contrast-enhanced imaging. We evaluated the time course of the contrast leak within the ICH at the source image of the DSC-MRI and the volume change of ICH between non-contrast CT and DSC-MRI. We compared the number of slices showing CTA-spots and DSC-MRI leaks. Results: The CTA-spot and DSC-MRI leak-sign were present in four patients, and two patients among those showed ICH-Ex. The time from the symptom onset to CTA or DSC-MRI was shorter for those with a DSC-MRI leak or CTA-spot than for three patients without either (70-130 minutes vs. 135-270 minutes). The leak-sign began earlier, lasted longer, and spread to more slices in the patients with ICH-Ex than in those without ICH-Ex. The number of slices of the DSC-MRI leak and the number of the CTA-spot were well correlated. Conclusion: DSC-MRI can demonstrate the leakage of GBCA within hyperacute ICH, showing the good contrast between hematoma and contrast. The DSC-MRI leakage sign could be related to the hematoma expansion in patients with ICH.

• Journal of the Korean Society of Radiology
• /
• v.79 no.6
• /
• pp.340-347
• /
• 2018

Purpose: To evaluate value of image subtraction for identifying hepatocellular carcinoma (HCC) capsule on gadoxetic acid-enhanced MR images. Materials and Methods: This study involved 108 patients at risk of HCC preoperatively examined using gadoxetic acid-enhanced MRI with hepatic resection between May 2015 and February 2017. We evaluated qualities of subtraction images and presence of capsular appearance on portal venous or transitional phases conventional and subtraction images. We assessed effect of capsular appearance on subtraction images on HCC. Results: After excluding 1 patient who had treated by transarterial chemoembolization prior to surgery and 33 patients with unsatisfactory subtraction image qualities, 82 focal hepatic lesions (73 HCC, 5 non-HCC malignancies, and 4 benign) from 74 patients were analyzed. Regarding detection of capsules, sensitivity, accuracy, and area under the receiver operating characteristic curve (AUC) on subtraction images were significantly higher than those on conventional images (95.4%, 89.0%, and 0.80, respectively; p < 0.001), though specificities were same (64.7%). For diagnosis of HCC, sensitivity, accuracy, and AUC on subtraction images were significantly higher than on conventional images (82.2%, 79.3%, and 0.69, respectively; p = 0.011), though specificities were identical (55.6%). Conclusion: Portal venous or transitional phase gadoxetic acid-enhanced MRI subtraction images could improve detection of HCC capsule.

• Korean Journal of Radiology
• /
• v.25 no.4
• /
• pp.363-373
• /
• 2024

Objective: To develop and evaluate a deep learning model for automated segmentation and detection of bone metastasis on spinal MRI. Materials and Methods: We included whole spine MRI scans of adult patients with bone metastasis: 662 MRI series from 302 patients (63.5 ± 11.5 years; male:female, 151:151) from three study centers obtained between January 2015 and August 2021 for training and internal testing (random split into 536 and 126 series, respectively) and 49 MRI series from 20 patients (65.9 ± 11.5 years; male:female, 11:9) from another center obtained between January 2018 and August 2020 for external testing. Three sagittal MRI sequences, including non-contrast T1-weighted image (T1), contrast-enhanced T1-weighted Dixon fat-only image (FO), and contrast-enhanced fat-suppressed T1-weighted image (CE), were used. Seven models trained using the 2D and 3D U-Nets were developed with different combinations (T1, FO, CE, T1 + FO, T1 + CE, FO + CE, and T1 + FO + CE). The segmentation performance was evaluated using Dice coefficient, pixel-wise recall, and pixel-wise precision. The detection performance was analyzed using per-lesion sensitivity and a free-response receiver operating characteristic curve. The performance of the model was compared with that of five radiologists using the external test set. Results: The 2D U-Net T1 + CE model exhibited superior segmentation performance in the external test compared to the other models, with a Dice coefficient of 0.699 and pixel-wise recall of 0.653. The T1 + CE model achieved per-lesion sensitivities of 0.828 (497/600) and 0.857 (150/175) for metastases in the internal and external tests, respectively. The radiologists demonstrated a mean per-lesion sensitivity of 0.746 and a mean per-lesion positive predictive value of 0.701 in the external test. Conclusion: The deep learning models proposed for automated segmentation and detection of bone metastases on spinal MRI demonstrated high diagnostic performance.

• Proceedings of the IEEK Conference
• /
• 2002.07a
• /
• pp.285-288
• /
• 2002

Compression of magnetic resonance images (MRI) has proved to be more difficult than other medical imaging modalities. In an average sized hospital, many tora bytes of digital imaging data (MRI) are generated every year, almost all of which has to be kept. The medical image compression is currently being performed by using different algorithms. In this paper, Fuzzy C-Means (FCM) algorithm is used for the Vector Quantization (VQ). First, a digital image is divided into subblocks of fixed size, which consists of 4${\times}$4 blocks of pixels. By performing 2-D Discrete Cosine Transform (DCT), we select six DCT coefficients to form the feature vector. And using FCM algorithm in constructing the VQ codebook. By doing so, the algorithm can make good time quality, and reduce the processing time while constructing the VQ codebook.

• Proceedings of the KSMRM Conference
• /
• 2003.10a
• /
• pp.71-71
• /
• 2003

For fast MRI, the number of phase encoding steps has to be reduced. However, the reconstructed image is aliased if the phase encoding steps don't satisfy Nyquist sampling theory. SENSE is used in order to eliminate the aliasing effect as well as to reduce imaging time. SENSE is a linear algebraic technique applied to the multiple receiver data. In this study, we implement a tool to reconstruct the original image (SENSE image) with Sensitivity Encoding (SENSE)