• 대한간호학회지
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• 제41권1호
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• pp.92-100
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• 2011

Purpose: Mortality Provability Model (MPM) II is a model for predicting mortality probability of patients admitted to ICU. This study was done to test the validity of MPM II for critically ill neurological patients and to determine applicability of MPM II in predicting mortality of neurological ICU patients. Methods: Data were collected from medical records of 187 neurological patients over 18 yr of age who were admitted to the ICU of C University Hospital during the period from January 2008 to May 2009. Collected data were analyzed through $X^2$ test, t-test, Mann-Whiteny test, goodness of fit test, and ROC curve. Results: As to mortality according to patients' general and clinically related characteristics, mortality was statistically significantly different for ICU stay, hospital stay, APACHE III score, APACHE predicted death rate, GCS, endotracheal intubation, and central venous catheter. Results of Hosmer-Lemeshow goodness-of-fit test were MPM $II_0$ ($X^2$=0.02, p=.989), MPM $II_24$ ($X^2$=0.99 p=.805), MPM $II_48$ ($X^2$=0.91, p=.822), and MPM $II_72$ ($X^2$=1.57, p=.457), and results of the discrimination test using the ROC curve were MPM $II_0$, .726 (p<.001), MPM $II_24$, .764 (p<.001), MPM $II_48$, .762 (p<.001), and MPM $II_72$, .809 (p<.001). Conclusion: MPM II was found to be a valid mortality prediction model for neurological ICU patients.

• 한국방송∙미디어공학회:학술대회논문집
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• 한국방송∙미디어공학회 2019년도 추계학술대회
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• pp.17-19
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• 2019

ISO/IEC JTC1 WG11 Moving Picture Expers Group 과 ITU-T SC16 은 Joint Video Experts Team 을 구성하여 차세대 비디오 부호화 표준으로서 Versatile Video Coding(VVC)를 표준화 중이다. VVC 는 현재 블록의 화면내 예측 모드일 가능성이 높은 모드의 집합인 Most Probable Mode(MPM) 리스트를 유도하고, MPM 을 이용하여 효율적으로 화면내 예측 모드를 부호화한다. VVC 는 주변 블록의 화면내 예측 모드에 따라 7가지 종류의 MPM 리스트 유도 방식을 가지고 있으나 이 중 두 가지는 동일한 MPM 들로 유도되는 중복성이 있다. 따라서 본 논문은 이 중복성 문제를 해결하기 위한 MPM 유도 방법을 제안한다. 제안 방법은 MPM 유도조건을 수정하여 중복적인 유도 방식이 제거된 6 가지 MPM 리스트 유도 방식을 갖는다. 실험을 통해 제안방법이 부호화 효율에 전혀 영향을 주기 않고 MPM 유도 과정을 단순화시켰음을 보인다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3405-3409
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• 2016

Malignant pleural mesothelioma (MPM), an aggressive malignant tumor of mesothelial origin associated with asbestos exposure, shows a limited response to conventional chemotherapy and radiotherapy. Therefore, the overall survival of MPM patients remains very poor. Progress in the development of therapeutic strategies for MPM has been limited. We recently reported that the calpain inhibitor, calpeptin exerted inhibitory effects on pulmonary fibrosis by inhibiting the proliferation of lung fibroblasts. In the present study, we examined the preventive effects of calpeptin on the cell growth of MPM, the origin of which is mesenchymal cells, similar to lung fibroblasts. Calpeptin inhibited the proliferation of MPM cells, but not mesothelial cells. It also prevented 1) the expression of angiopoietin (Ang)-1 and Tie-2 mRNA in MPM cells, but not mesothelial cells and 2) the Ang-1-induced proliferation of MPM cells through an NF-kB dependent pathway, which may be the mechanism underlying the preventive effects of calpeptin on the growth of MPM cells. These results suggest potential clinical use of calpeptin for the treatment of MPM.

• 한국식품영양학회지
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• 제25권4호
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• pp.903-910
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• 2012

This study was conducted to examine the applicability of muffins and the optimal ratio of batter mixture by adding mugwort with various functions and physiological active substances. In result of examining the quality characteristics of muffins after adding frozen-dried mugwort powder by 0%, 1%, 3%, 5%, or 7%, the moisture retaining capacity of muffin batter was lowest with MPM0, the control group, and the deposition was highest at $17.94m{\ell}$ with MPM0. The pH value of muffin batter was highest at 8.62 with MPM0 and moisture decreased significantly (p<0.001) when more mugwort powder was added to the sample. The brightness increased significantly (p<0.001) when the amount of frozen-dried mugwort powder decreased and redness and yellowness decreased when the addition of mugwort powder increased. The height and volume of mugwort muffins were lowest at 4.75 cm and $135.69m{\ell}$ with MPM7 with the greatest value of frozen-dried mugwort powder. The loss at baking of mugwort muffins was lowest at 2.27% with MPM7. The hardness of mugwort muffins was highest with MPM7 with the highest mugwort powder content. Coagulation and resilience was highest at 0.64 with the MPM0 control group and the chewiness increased significantly (p<0.001) with greater amount of frozen-dried mugwort powder. The appearance of mugwort muffins was highest at 6.1 with MPM5 and the most preferable color and flavors were found with MPM3. Tenderness was highest with the MPM0 control group. Overall preferability was highest with MPM3 with 3% frozen-dried mugwort powder. When adding frozen-dried mugwort powder to muffins, the 3% and control groups mostly showed the highest values, whereas the 5% group and higher groups showed lower values.

• Asian Pacific Journal of Cancer Prevention
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• 제15권1호
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• pp.331-334
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• 2014

There is a scarcity of reports addressing patients with multiple primary malignancies (MPM), especially for Chinese cses. The aim of this study was to present a detailed analysis of Chinese patients presenting with at least two primary malignancies. Particularly, the clinical characteristics and survival between synchronous and metachronous MPM were compared. Out of 6,545 cases, 72 patients (1.1%) including 39 males (54.2%) and 33 females (45.8%) were diagnosed as MPM, giving a male: female sex ratio of 1.2:1. Of these, there were 16 (22.2%) cases of synchronous MPM (7 males, 9 females), 55(76.4%) metachronous (31 males, 24 females), and 1 "mixed form". For first tumor diagnosis time, synchronous MPM patients generally presented later than the metachronous cases. The top three sites for malignancies with metachronous MPM were colorectum, head and neck, and lung, while for synchronous they were lung, colorectum and breast. Among MPM patients, the median survival time was 15.7 years and the 5-year survival was 56%, and there was statistical difference in MPM categories (P < 0.05). The median survival time was 17.3 years and 3.8 years for metachronous and synchronous MPM patients, respectively. In comparison with synchronous MPM patients, those metachronous had a longer survival. This studies increase understanding of the clinical features of Chinese MPM patients and suggest that those presenting with metachronous cancers have a higher incidence and a better prognosis.

• Nuclear Medicine and Molecular Imaging
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• 제42권sup1호
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• pp.157-161
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• 2008

Malignant pleural mesothelioma (MPM) has a poor prognosis and a strong association with exposure to asbestos. Although there are not generally accepted guidelines for treatment of MPM, recent reports suggest that multi modality therapy combining chemotherapy, radiotherapy, and surgery can improve the survival of patients with MPM. Therefore exact staging is required to decide the best treatment option. However, it is well known that there are many difficulties in determining precise preoperative stage, predicting prognosis, and monitoring response to therapy with conventional imaging modalities such as CT and MRI in MPM. Recently PET with $^{18}F-FDG$ comes into the spotlight as an important staging method. There is increasing evidence that PET is superior to other conventional imaging modalities in diagnosis and staging of MPM. Particularly PET/CT improves the diagnostic and staging accuracy over PET or CT alone in MPM because it provides anatomic imaging data as well as functional information. PET and PET/CT are also useful for monitoring response to therapy and SUV is reported as a prognostic factor in MPM.

• KSBB Journal
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• 제25권1호
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• pp.103-107
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• 2010

Oil degradation agent was developed with organic sludge and modified peat moss (MPM) to recover oil contaminated soil. Waste sludge discharged from wastewater treatment plant of chemical plant in Ulsan National Industrial Park was used as organic sludge, and MPM was purchased. Organic sludge was adequate to use as growth medium for microorganism, the surface of MPM had porous structure which could enhance the cultivation condition of oil degradation microorganisms. Water contents and TPH variation with time were observed to investigate the degradation capacity of developed degradation agent. Water contents were rapidly decreased with higher contents of MPM, however, in case of TPH, high MPM content decreased the degradation capacity. Therefore, it was recommended that the content of MPM was controlled to below 10% in degradation agent as mixing organic sludge with MPM.

• 한국ITS학회 논문지
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• 제5권1호
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• pp.13-19
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• 2006

본 논문에서는 7 - 11 GHz 대역에서 동작하는 광대역 Microwave Power Module (MPM)을 설계하고 제작하였다. MPM 은 TWT (Traveling Wave Tube)와 SSA (Solid State Amplifier)로 구성되며, TWT와 SSA의 이득을 최적으로 배분하여 잡음지수를 줄일 수 있도록 설계하였다. Agilent사의 ADS (Advanced Design System)을 이용하여 SSA의 컴퓨터 모델링과 시뮬레이션을 수행 하였으며, 직렬 분포형 증폭기 구조를 이용하여 설계 및 제작하였다. 제작된 광대역 MPM은 7 - 11 GHz 대역에서 8.3 - 10.02 dB의 잡음 지수, 9 GHz에서 38.12 dBm의 출력 전력이 측정되었다.

• 대한전자공학회논문지SP
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• 제43권2호
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• pp.87-92
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• 2006

Array 신호처리에서 복소 지수함수의 합으로 구성된 신호의 파라미터를 추정하는데 고차 통계를 이용할 수 있다. 본 논문에서는 4차 cumulant를 이용한 고차 Matrix Pencil method(MPM)를 제안하였다. 4차 cumulant는 Gaussian 잡음를 억제할 수 있기 때문에, MPM의 응답은 기존의 방법에 비하여 더 좋은 잡음 면역을 가지고 있다. 본 논문에서는 높은 정확성을 가지는 MPM의 모든 장점을 유지하면서 성공적으로 고차 MPM을 공식화하였다. 그리고 Numerical simulation을 통해서 본 논문에서 제안된 4차 cumulant를 이용한 방법이 Gaussian 잡음환경에서 더 우수한 DOA 분해능을 가지고 있음을 증명하였다.

• 한국컴퓨터그래픽스학회논문지
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• 제28권4호
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• pp.13-22
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• 2022

본 논문에서는 최소 입자 단위의 역동적인 회전 움직임을 나타낼 수 있는 MPM(Material Point Method) 기반 단일 프레임워크를 소개한다. 우리가 표현하고자 하는 입자는 다양한 형상(Shape)을 가질 수 있음과 동시에, 선형(Linear momentum), 회전(Angular momentum) 운동을 함께 묘사할 수 있다. 그 결과 기존 구형 입자의 선형 움직임만을 나타내던 입자 기반 시뮬레이션과는 달리, 시각적으로 단일 입자의 역동적인 모습을 표현할 수 있다. 제안하는 프레임워크는 회전 운동을 큰 변형(Large Deformation)으로부터 분해 및 추출 할 수 있다는 점에서 MPM을 활용하였다. 본 기법은 MPM 적분 과정 중 계산되는 변형 구배 텐서(Deformation Gradient Tensor)를 극 분해(Polar Decomposition)하는 과정을 통해 회전 텐서(Rotation Tensor)를 추출하고, 각 입자의 선형 운동과 함께 이를 적용하여 결과적으로 입자 자체의 회전, 선형 운동을 동시에 표현 하는 것이 가능하다. 본 연구에서는 제안하는 기법의 검증을 위해 바람에 흩날리며 회전하는 입자의 모습 및 움직이는 물체와 정지한 입자간의 상호작용 시뮬레이션을 기존 MPM을 이용한 시뮬레이션과의 비교를 통해 진행하였다.