• Title/Summary/Keyword: MPM

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Verification of Validity of MPM II for Neurological Patients in Intensive Care Units (신경계중환자의 사망예측모델(Mortality Probability Model II)에 대한 타당도 검증)

  • Kim, Hee-Jeong;Kim, Kyung-Hee
    • Journal of Korean Academy of Nursing
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    • v.41 no.1
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    • pp.92-100
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    • 2011
  • Purpose: Mortality Provability Model (MPM) II is a model for predicting mortality probability of patients admitted to ICU. This study was done to test the validity of MPM II for critically ill neurological patients and to determine applicability of MPM II in predicting mortality of neurological ICU patients. Methods: Data were collected from medical records of 187 neurological patients over 18 yr of age who were admitted to the ICU of C University Hospital during the period from January 2008 to May 2009. Collected data were analyzed through $X^2$ test, t-test, Mann-Whiteny test, goodness of fit test, and ROC curve. Results: As to mortality according to patients' general and clinically related characteristics, mortality was statistically significantly different for ICU stay, hospital stay, APACHE III score, APACHE predicted death rate, GCS, endotracheal intubation, and central venous catheter. Results of Hosmer-Lemeshow goodness-of-fit test were MPM $II_0$ ($X^2$=0.02, p=.989), MPM $II_24$ ($X^2$=0.99 p=.805), MPM $II_48$ ($X^2$=0.91, p=.822), and MPM $II_72$ ($X^2$=1.57, p=.457), and results of the discrimination test using the ROC curve were MPM $II_0$, .726 (p<.001), MPM $II_24$, .764 (p<.001), MPM $II_48$, .762 (p<.001), and MPM $II_72$, .809 (p<.001). Conclusion: MPM II was found to be a valid mortality prediction model for neurological ICU patients.

Simplified MPM derivation for Versatile Video Coding (VVC 표준의 MPM 유도 단순화 방법)

  • Choe, Jaeryun;Gwon, Daehyeok;Han, Heeji;Lee, Hahyun;Kang, Jungwon;Choi, Haechul
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2019.11a
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    • pp.17-19
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    • 2019
  • ISO/IEC JTC1 WG11 Moving Picture Expers Group 과 ITU-T SC16 은 Joint Video Experts Team 을 구성하여 차세대 비디오 부호화 표준으로서 Versatile Video Coding(VVC)를 표준화 중이다. VVC 는 현재 블록의 화면내 예측 모드일 가능성이 높은 모드의 집합인 Most Probable Mode(MPM) 리스트를 유도하고, MPM 을 이용하여 효율적으로 화면내 예측 모드를 부호화한다. VVC 는 주변 블록의 화면내 예측 모드에 따라 7가지 종류의 MPM 리스트 유도 방식을 가지고 있으나 이 중 두 가지는 동일한 MPM 들로 유도되는 중복성이 있다. 따라서 본 논문은 이 중복성 문제를 해결하기 위한 MPM 유도 방법을 제안한다. 제안 방법은 MPM 유도조건을 수정하여 중복적인 유도 방식이 제거된 6 가지 MPM 리스트 유도 방식을 갖는다. 실험을 통해 제안방법이 부호화 효율에 전혀 영향을 주기 않고 MPM 유도 과정을 단순화시켰음을 보인다.

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Calpeptin Prevents Malignant Pleural Mesothelioma Cell Proliferation via the Angiopoietin-1/Tie-2 System

  • Tabata, Chiharu;Tabata, Rie;Nakano, Takashi
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.7
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    • pp.3405-3409
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    • 2016
  • Malignant pleural mesothelioma (MPM), an aggressive malignant tumor of mesothelial origin associated with asbestos exposure, shows a limited response to conventional chemotherapy and radiotherapy. Therefore, the overall survival of MPM patients remains very poor. Progress in the development of therapeutic strategies for MPM has been limited. We recently reported that the calpain inhibitor, calpeptin exerted inhibitory effects on pulmonary fibrosis by inhibiting the proliferation of lung fibroblasts. In the present study, we examined the preventive effects of calpeptin on the cell growth of MPM, the origin of which is mesenchymal cells, similar to lung fibroblasts. Calpeptin inhibited the proliferation of MPM cells, but not mesothelial cells. It also prevented 1) the expression of angiopoietin (Ang)-1 and Tie-2 mRNA in MPM cells, but not mesothelial cells and 2) the Ang-1-induced proliferation of MPM cells through an NF-kB dependent pathway, which may be the mechanism underlying the preventive effects of calpeptin on the growth of MPM cells. These results suggest potential clinical use of calpeptin for the treatment of MPM.

Quality Characteristics of Muffins Prepared with Freeze Dried-mugwort Powder (동결 건조 쑥 분말을 첨가한 머핀의 품질 특성)

  • Jang, Sang Jun
    • The Korean Journal of Food And Nutrition
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    • v.25 no.4
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    • pp.903-910
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    • 2012
  • This study was conducted to examine the applicability of muffins and the optimal ratio of batter mixture by adding mugwort with various functions and physiological active substances. In result of examining the quality characteristics of muffins after adding frozen-dried mugwort powder by 0%, 1%, 3%, 5%, or 7%, the moisture retaining capacity of muffin batter was lowest with MPM0, the control group, and the deposition was highest at $17.94m{\ell}$ with MPM0. The pH value of muffin batter was highest at 8.62 with MPM0 and moisture decreased significantly (p<0.001) when more mugwort powder was added to the sample. The brightness increased significantly (p<0.001) when the amount of frozen-dried mugwort powder decreased and redness and yellowness decreased when the addition of mugwort powder increased. The height and volume of mugwort muffins were lowest at 4.75 cm and $135.69m{\ell}$ with MPM7 with the greatest value of frozen-dried mugwort powder. The loss at baking of mugwort muffins was lowest at 2.27% with MPM7. The hardness of mugwort muffins was highest with MPM7 with the highest mugwort powder content. Coagulation and resilience was highest at 0.64 with the MPM0 control group and the chewiness increased significantly (p<0.001) with greater amount of frozen-dried mugwort powder. The appearance of mugwort muffins was highest at 6.1 with MPM5 and the most preferable color and flavors were found with MPM3. Tenderness was highest with the MPM0 control group. Overall preferability was highest with MPM3 with 3% frozen-dried mugwort powder. When adding frozen-dried mugwort powder to muffins, the 3% and control groups mostly showed the highest values, whereas the 5% group and higher groups showed lower values.

Clinical Features of Multiple Primary Malignancies: a Retrospective Analysis of 72 Chinese Patients

  • Jiao, Feng;Yao, Li-Juan;Zhou, Jin;Hu, Hai;Wang, Li-Wei
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.331-334
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    • 2014
  • There is a scarcity of reports addressing patients with multiple primary malignancies (MPM), especially for Chinese cses. The aim of this study was to present a detailed analysis of Chinese patients presenting with at least two primary malignancies. Particularly, the clinical characteristics and survival between synchronous and metachronous MPM were compared. Out of 6,545 cases, 72 patients (1.1%) including 39 males (54.2%) and 33 females (45.8%) were diagnosed as MPM, giving a male: female sex ratio of 1.2:1. Of these, there were 16 (22.2%) cases of synchronous MPM (7 males, 9 females), 55(76.4%) metachronous (31 males, 24 females), and 1 "mixed form". For first tumor diagnosis time, synchronous MPM patients generally presented later than the metachronous cases. The top three sites for malignancies with metachronous MPM were colorectum, head and neck, and lung, while for synchronous they were lung, colorectum and breast. Among MPM patients, the median survival time was 15.7 years and the 5-year survival was 56%, and there was statistical difference in MPM categories (P < 0.05). The median survival time was 17.3 years and 3.8 years for metachronous and synchronous MPM patients, respectively. In comparison with synchronous MPM patients, those metachronous had a longer survival. This studies increase understanding of the clinical features of Chinese MPM patients and suggest that those presenting with metachronous cancers have a higher incidence and a better prognosis.

Clinical Application of $^{18}F-FDG$ PET in Malignant Mesothelioma (악성중피종에서 $^{18}F-FDG$ PET의 임상응용)

  • Lee, Eun-Jeong
    • Nuclear Medicine and Molecular Imaging
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    • v.42 no.sup1
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    • pp.157-161
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    • 2008
  • Malignant pleural mesothelioma (MPM) has a poor prognosis and a strong association with exposure to asbestos. Although there are not generally accepted guidelines for treatment of MPM, recent reports suggest that multi modality therapy combining chemotherapy, radiotherapy, and surgery can improve the survival of patients with MPM. Therefore exact staging is required to decide the best treatment option. However, it is well known that there are many difficulties in determining precise preoperative stage, predicting prognosis, and monitoring response to therapy with conventional imaging modalities such as CT and MRI in MPM. Recently PET with $^{18}F-FDG$ comes into the spotlight as an important staging method. There is increasing evidence that PET is superior to other conventional imaging modalities in diagnosis and staging of MPM. Particularly PET/CT improves the diagnostic and staging accuracy over PET or CT alone in MPM because it provides anatomic imaging data as well as functional information. PET and PET/CT are also useful for monitoring response to therapy and SUV is reported as a prognostic factor in MPM.

Development of Degradation Agent for Oil Contaminated Soil using Modified Peat Moss and Organic Sludge (개량된 이탄과 유기성 슬러지를 이용한 유류오염토양 분해제 개발)

  • Kim, Soo-Hong;Lee, Chang-Han;Suh, Jung-Ho
    • KSBB Journal
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    • v.25 no.1
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    • pp.103-107
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    • 2010
  • Oil degradation agent was developed with organic sludge and modified peat moss (MPM) to recover oil contaminated soil. Waste sludge discharged from wastewater treatment plant of chemical plant in Ulsan National Industrial Park was used as organic sludge, and MPM was purchased. Organic sludge was adequate to use as growth medium for microorganism, the surface of MPM had porous structure which could enhance the cultivation condition of oil degradation microorganisms. Water contents and TPH variation with time were observed to investigate the degradation capacity of developed degradation agent. Water contents were rapidly decreased with higher contents of MPM, however, in case of TPH, high MPM content decreased the degradation capacity. Therefore, it was recommended that the content of MPM was controlled to below 10% in degradation agent as mixing organic sludge with MPM.

Design and fabrication on 7-11 GHz, Broadband MPM (7-11 GHz, 광대역 MPM 설계 및 제작)

  • Choi Gil-Woong;Lee Yu-Ri;Kim Ki-Ho;Choi Jin-Joo;So Joon-Ho
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.5 no.1 s.9
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    • pp.13-19
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    • 2006
  • In this paper, a broadband Microwave Power Module(MPM) operating at 7 - 11 GHz is designed and fabricated. The MPM consists of a SSA (Solid State Amplifier) and a conventional TWT (traveling Wave Tube). This combined module takes advantage of a low noise and high gain of SSA. The computer modeling and simulation of the SSA are designed by the use of the ADS (Advanced Design System) software. The SSA is designed by configurating the CSSDA (Cascaded Single Stage Distributed Amplifier). The broadband MPM is measured to be noise figure 8.3 - 10.02 dB at 7 - 11 GHz bandwidth, output power of 38.12 dBm at 9 GHz.

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Matrix Pencil Method using Fourth Order Cumulant (4차 Cumulant를 이용한 Matrix Pencil Method)

  • Jang Woo-Jin;Koh Jin-Hwan
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.43 no.2 s.308
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    • pp.87-92
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    • 2006
  • In array signal processing, high order statistics can be used to estimate parameters from signal of sums of complex exponential. This paper presents a high order Matrix Pencil method(MPM) using the fourth order cumulant. Since the fourth order cumulant can suppress the Gaussian noise, the response of MPM has better noise immunity than the conventional approaches. We successfully formulate the high order MPM with all the benefits of MPM along with higher accuracy. In the numerical simulations we demonstrated that the proposed method with forth order cumulant has better resolution to find degree of arrival(DOA) in the presence of the Gaussian noise.

MPM-Based Angular Animation of Particles using Polar Decomposition Theory (극 분해 이론을 활용한 MPM기반의 입자 회전 애니메이션)

  • Song, Chang-yong;Kim, Ki-hoon;Kim, Sun-jeong;Kim, Changhun
    • Journal of the Korea Computer Graphics Society
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    • v.28 no.4
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    • pp.13-22
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    • 2022
  • In this paper, we propose a single framework based on the MPM(Material Point Method) that can represent the dynamic angular motion of the elementary particle unit. In this study, the particles can have various shapes while also describing linear and angular motion. As a result, unlike other particle-based simulations, which only represent linear movements of spherical (e.g. Circle, Sphere) particles, it is possible to express the visually dynamic motion of them. The proposed framework utilizes MPM, due to the fact that rotational motion can be decomposed and derived from large deformation. During the integration process of the presented technique, a deformation gradient tensor is decomposed by polar decomposition theory for extracting rotation tensor. By applying this together with the linear motion of each particle, as a result, it is possible to simultaneously express the angluar and linear motion of the particle itself. To verify the proposed method, we show the simulation of rotating particles scattering in the wind field, and the interaction(e.g. Collision) between a moving object and them by comparing the traditional MPM