• 정보관리학회지
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• 제33권3호
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• pp.345-370
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• 2016

최근 국가기록원은 표준영구기록관리시스템 개발 계획을 검토하였다. 서울시 등의 지방기록물관리기관 건립에 따라 경제적이고 효율적인 영구기록관리시스템 구축을 지원하기 위함이다. 또한 국가기록원은 디지털 아카이브 구축과 전문인력 양성을 위해 한국정보화진흥원과 업무협약을 체결하였다. 이러한 움직임은 디지털 아카이브에 대한 국내 수요에 기반한 것이다. 이 연구의 목적은 국내의 디지털 아카이브 시스템 구축 수요에 대응하여 지속 가능하며 효율적인 시스템 구축 방안을 제시하는 것이다. 이를 위해 국내외 디지털 아카이브 시스템 현황과 공개 소프트웨어 분석 프로젝트를 조사하였다. 도출된 시사점을 바탕으로 디지털 아카이브 시스템 구축을 위한 기능 모듈 도출 방법과 각 기능모듈에 공개 소프트웨어를 활용하기 위한 방안을 제시하였다. 또한 공개 소프트웨어 기반으로 시스템을 설계할 때 필요한 재정적, 운영적 요건과 모듈 간의 연계 등 기술적 고려사항을 정리하였다.

• Asian Pacific Journal of Cancer Prevention
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• 제15권3호
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• pp.1481-1488
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• 2014

Background: To avoid performing axillary lymph node dissection (ALND) for non-sentinel lymph node (SLN)-negative patients with-SLN positive axilla, nomograms for predicting the status have been developed in many centers. We created a new nomogram predicting non-SLN metastasis in SLN-positive patients with invasive breast cancer and evaluated 14 existing breast cancer models in our patient group. Materials and Methods: Two hundred and thirty seven invasive breast cancer patients with SLN metastases who underwent ALND were included in the study. Based on independent predictive factors for non-SLN metastasis identified by logistic regression analysis, we developed a new nomogram. Receiver operating characteristics (ROC) curves for the models were created and the areas under the curves (AUC) were computed. Results: In a multivariate analysis, tumor size, presence of lymphovascular invasion, extranodal extension of SLN, large size of metastatic SLN, the number of negative SLNs, and multifocality were found to be independent predictive factors for non-SLN metastasis. The AUC was found to be 0.87, and calibration was good for the present Ondokuz Mayis nomogram. Among the 14 validated models, the MSKCC, Stanford, Turkish, MD Anderson, MOU (Masaryk), Ljubljana, and DEU models yielded excellent AUC values of > 0.80. Conclusions: We present a new model to predict the likelihood of non-SLN metastasis. Each clinic should determine and use the most suitable nomogram or should create their own nomograms for the prediction of non- SLN metastasis.

• 한국항해학회지
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• 제25권2호
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• pp.159-172
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• 2001

The information technology(IT) development of telecommunication, along with the information analyzation over the world, enables the firms to process their inner and outer operations through Electronic Data Interchange (EDI) system. And the concept of logistics has become more important to the enterprises in strategic sense because it had aggrandized itself to more comprehensive and integrative concept. Also the world shipping market is more competitive than any other market. In these environment, to maintain competitive power, shipping firms process operations by Logistics Information system(LIS), And then, reduce the working processes, working time and its costs. So the LIS has become more important in developing our national logistics system and industry. Therefore, this study purposes on empirically analyzing the activation factors of shipping LIS and the relationship these, factors with logistic performances in the shipping industry. Considering environments of Shipping logistics information system, this study sets up the research model and hypothesis to examine the activation factors of shipping LIS and the relationship these factors with logistic performances. We used the field data on the 163 numbers of firms(29 overseas shipping companies and 133 forwarding Agency) to get the empirical evidence. According to the study results, The shipping LIS activation factors which the sample firms recognized as important: were top managers support, well structured communication channel, strategic plans connection and inner information analyzation level. And IS organization & human resources, IS discipline & training, software development, IS organizational alignment, database management system, information standardization, competitive advantage, financial support and government support represent partially significant. Also, the current shipping LISs main problems are expensive system cost, standardization of working processs, institutions imperfection and systems interaction defect. So these problems must be improved to activate shipping LIS.

• 디지털융복합연구
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• 제18권11호
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• pp.169-176
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• 2020

정보기술의 발전에 따라 정보보안의 중요성이 갈수록 커지고 있다. 정보보안의 근본적인 방향을 제시하고 조직 구성원이 따라야 하는 규정과 지침을 다루는 보안정책은 보안관리의 핵심적인 요소이며, 조직 구성원의 보안정책 준수에 영향을 미치는 다양한 요인에 대한 연구들이 다수 수행되었다. 이들 연구는 다양한 이론적 기반으로 수행되었으며, 여러 문헌연구에 따르면 계획된 행동이론이 가장 빈번하게 사용되었다. 본 연구는 기존의 다양한 연구결과를 정량적으로 종합하는 메타분석 기법 중의 하나인 TSSEM을 적용하여 정보보안 정책준수 행동에 영향을 미치는 요인을 계획된 행동이론을 기반으로 실증분석한 연구들을 대상으로 분석하였다. 분석결과 계획된 행동이론의 행동의도를 설명하는 세가지 요인인 태도, 주관적 규범 및 인지된 행동통제 모두 유의한 영향을 미쳤으며, 구조방정식 모형의 전반적인 적합도도 만족스럽게 나타났다.

• 한국비블리아학회지
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• 제23권1호
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• pp.131-151
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• 2012

최근 공공기관은 물론 학술정보 서비스 기관에서는 보유하고 있는 정보자원을 외부 기관과 공유함으로써 자원의 재활용을 통해 새로운 가치를 창출할 수 있도록 하고 있다. 특히 학술정보 서비스 기관은 디지털 콘텐츠의 확산 정책을 명문화함으로써, 학술정보 서비스의 일관성과 신뢰성, 정체성과 효율성을 제고시킬 필요가 있다. 이 연구에서는 학술정보 서비스 기관의 디지털 콘텐츠 확산 정책 수립을 위하여 국내외 디지털 콘텐츠 서비스 정책 및 확산 정책의 사례를 파악한 후, 한국과학기술정보연구원의 국가과학기술정보센터(NDSL)를 중심으로 확산 정책을 수립하였다. 디지털 콘텐츠 확산 정책의 주요 내용으로 목적 및 목표, 주 이용자, 확산 범위, 확산 방식, 활용에 대한 신청, 동의 및 협약 등을 제시하였다. 이 연구는 향후 유관 학술정보 서비스 기관의 디지털 콘텐츠 공유 및 확산을 위한 정책 도출에 기반이 될 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권9호
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• pp.3867-3870
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• 2015

Background: To explore whether combined detection of serum tumor markers (CEA, CA72-4, CA19-9 and TSGF) improve the sensitivity and accuracy in the diagnosis of gastric cancer (GC). Materials and Methods: An automatic chemiluminescence immune analyzer with matched kits were used to determine the levels of serum CEA, CA72-4, CA19-9 and TSGF in 45 patients with gastric cancer (GC group), 40 patients with gastric benign diseases (GBD group) hospitalized in the same period and 30 healthy people undergoing a physical examination. The values of those 4 tumor markers in the diagnosis of gastric cancer was analyzed. Results: The levels of serum CEA, CA72-4, CA19-9 and TSGF of the GC group were higher than those of the GBD group and healthy examined people and the differences were significant (P<0.001). The area under receiver operating characteristic (ROC) curves for single detection of CEA, CA72-4, CA19-9 and TSGF in the diagnosis of GC was 0.833, 0.805, 0.810 and 0.839, respectively. The optimal cutoff values for these 4 indices were 2.36 ng/mL, 3.06 U/mL, 5.72 U/mL and 60.7 U/mL, respectively. With combined detection of tumor markers, the diagnostic power of those 4 indices was best, with an area under the ROC curve of 0.913 (95%CI 0.866~0.985), a sensitivity of 88.9% and a diagnostic accuracy of 90.4%. Conclusions: Combined detection of serum CEA, CA72-4, CA19-9 and TSGF increases the sensitivity and accuracy in diagnosis of GC, so it can be regarded as the important means for early diagnosis.

• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4839-4842
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• 2013

Aims and Background: To improve understanding of the relationship between schistosome-related enteropathy and colorectal carcinoma with particular focus on endoscopic findings and clinicopathological characteristics of colonic schistosomiasis. Materials and Methods: All cases of intestinal schistosomiasis diagnosed at West China Hospital, Chengdu, China, between October 2006 and October 2012 were included in this study. A total of 179 cases of colonic schistosomiasis diagnosed through colonoscopy and pathological examinations were collected for analysis and the demographics, symptoms, endoscopic findings and clinicopathological characteristics were retrospectively evaluated. Results: Of the 179 colonic schistosomiasis patients, 32 combined with colorectal cancer (CRC) were found, between the ages of 44 and 85 years (24 males, 75%). These 32 lesions were classified as 12 endophytic/ulcerative (37.5%), 10 exophytic/fungating (31.2%), 4 annular (12.5%), 3 giant polypus (9.4%), and 3 IIc (superficial depressed type) (9.4%). The segments of rectum and sigmoid colon were involved in 19 patients (59.4%) and 6 patients (18.8%), respectively. The histopathologic types were classified as follows: 30 welldifferentiated adenocarcinomas, one mucinous adenocarcinoma and one poorly differentiated adenocarcinoma. The pathological findings suggest colorectal malignancy with deposited schistosome ova. Conclusions: Chronic schistosomal infestation has a probable etiological role in promoting genesis of colorectal neoplasms.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.1793-1797
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• 2012

Objective: To analyze the capacity of neurotrophic artemin to promote the motility and invasiveness of MIA PaCa-2 pancreatic cancer cells. Methods: MIA PaCa-2 was cultured in vitro and studied using transwell chambers for motility and invasiveness on treatment with different concentrations of aArtemin or its receptor $GFR{\alpha}3$ were also determined. Expression of matrix metalloproteinase-2 (MMP-2) and epithelial cadherin (E-cadherin) was quantified using RT-PCR and Western blotting. Results: MIA PaCa-2 pancreatic cancer cell motility and invasiveness was significantly increased with artemin and its receptor $GFR{\alpha}3$ with dose dependence (P<0.01). MMP-2 production was also significantly increased (t = 6.35, t = 7.32), while E-cadherin was significantly lowered (t = 4.27, t = 5.61) (P <0.01). Conclusion: Artemin and its receptor $GFR{\alpha}3$ can promote pancreatic cancer cell motility and invasiveness and contribute to aggressive behavior. The mechanism may be related to increased expression of MMP-2 molecule and down-regulation of E-cadherin expression.

• Journal of Acupuncture Research
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• 제19권2호
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• pp.14-27
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• 2002

Objective : The aim of this study is to reveal the meaning of Shi-Dong-Bing and Suo-Sheng-Bing through investigating the origin of Shi-Dong-Bing and Suo-Sheng-Bing. Methods : We analyzed and compared the meridian symptoms of "ju Bi Shi Yi Mai Jiu Jing, "Ju Bi", "Yin Yang Shi Yi Mai Jiu Jing" and "Lin Shu Jing Mai". Results : Suo-Sheng-Bing seems to have been originated from the meridian symptoms of "Ju Bi" and Shi-Dong-Bing is different from the meridian symptoms of "Ju Bi". therefore two meridian symptoms differ in the source of formation and they seems to be different concerning recognition system for disease. Conclusion : Shi-Dong-Bing is the meridian symptoms, in case of feeling abnormal beat by pulse diagnosis, and this pulse diagnosis method is comparative pulse diagnosis method that compare all the pulse point of every meridians. Suo-Sheng-Bing seems to be the meridian symptoms describing the disease of somatic surface with making reference to meridian-circulating positions, afterward have been increased to the related internal organ's disease.

• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 2009년도 한국우주과학회보 제18권2호
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• pp.32.4-32.4
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• 2009

한국천문연구원은 미국 텍사스대학교와 공동으로 근적외선 광대역 고분산 분광기 IGRINS (Immersion Grating Infrared Spectrograph)를 개발하고 있다. IGRINS는 R=40,000의 높은 분광분해능으로 H-밴드 ($1.49\sim1.80{\mu}m$)와 K-밴드 ($1.96\sim2.46{\mu}m$) 전체 분광스펙트럼을 한 번에 관측할 수 있다. IGRINS를 구성하는 핵심 부품은 실리콘 담금격자 (Silicon Immersion Grating)와 VPH (Volume Phased Holographic) 격자, 그리고 HAWAII2RG 적외선 센서이다. 실리콘 담금격자를 사용함으로써 적외선 분광기의 크기를 일반적인 격자를 사용한 것보다 2-3배정도 줄일 수 있게 되었다. IGRINS는 개발 후 미국 맥도날드 천문대에 3년간 장착하여 관측연구에 활용될 예정이다. 이후 IGRINS는 4미터급 이상의 망원경에 장착될 예정이다. 한국천문연구원은 IGRINS 국제공동 개발을 위하여 2009년 8월 텍사스 대학과 양해각서(MOU)를 교환하였으며 현재 개념 설계를 끝내고 기본 설계를 진행하고 있다. 기본설계검토 회의 (Preliminary Design Review)은 12월에 실시할 예정이다. 또한 과학연구 활용 극대화를 위하여 사용자 그룹을 조직하였으며, 여름학교를 열어 적외선 분광 연구에 대한 교육을 실시하였다. 이 발표에서는 IGRINS의 개발 현황을 보고하고, IGRINS의 설계와 활용 분야에 대하여 소개한다.