• Title/Summary/Keyword: MOR

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Effect of Deep Seawater on Expression of μ-Opioid Receptor in Cultured Rat Hippocampal Neurons (배양된 쥐 해마신경세포에서 μ-아편양 수용체의 발현에 대한 해양심층수의 영향)

  • Moon, Il-Soo;Kim, Seong-Ho
    • Journal of Life Science
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    • v.21 no.2
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    • pp.176-182
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    • 2011
  • Deep seawater (DSW) generally refers to seawater at depths equal to or greater than 200 meters. DSW is rich in inorganic materials which have attracted attention for its various applications. In this study we investigated the effects of the DSW upwelled from the East Sea, offshore Yang Yang (KangWon-do, Korea), on the expression of ${\mu}$-opioid receptor (MOR) of cultured rat hippocampal neurons. Neurons were grown in a minimal essential medium containing 10% (v/v) fetal bovine serum and either 25% (v/v) distilled water, or hardness (H) 800, or H 1000 DSW. Cultures grown in the presence of DSW with H 800 and H 1000 exhibited robust MOR immunoreactive signals in both neurons and astrocytes. Interestingly, the increase in MOR immunoreactive signals was more dramatic in astrocytes than in neurons. Statistical analysis revealed that the relative intensities for MOR clusters increased approximately 4-fold in astrocytes cultured in H 800 and H 1000 media. These increases were statistically very significant (p<0.001). In contrast, the increase in intensities for MOR immunoreactive signals was relatively less dramatic in neurons, where only the increase in the H 1000 culture was statistically very significant (p<0.001). These results indicated that DSW promotes expression of MOR in both neurons and astrocytes, and more significantly in the latter.

Prediction of The MOR of Larch Lumber (낙엽송 소경각재의 휨 파괴계수 예측)

  • Lee, In-Hwan;Cho, Soo-min;Hong, Soon-Il
    • Journal of the Korean Wood Science and Technology
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    • v.46 no.1
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    • pp.93-99
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    • 2018
  • It is necessary to review the non-destructive indexes in order to estimate the bending strength performance of the domestic larch lumber. In this study, MOEs (modulus of elastic) the larch lumber (cross-section $89{\times}120mm$) were evaluated through non-destructive methods such as the ultra-sonic method, longitudinal vibration method, and non-destructive bending method. The non-destructive measurement method which best represented the static MOE was determined and applied as the MOR(modulus of rupture) estimation index. The MOE that was measured through the longitudinal vibration method showed the highest correlation with the static MOE. The MOR was highly related to the static MOE. Therefore, the non-destruction MOE measured through the longitudinal vibration method was used to estimate the MOR of the lumber.

Nondestructive Bending Strength Evaluation of Miscanthus sinensis var. purpurascens Ceramics Made from Different Carbonizing Temperatures (탄화온도별로 제조된 거대억새 세라믹의 비파괴 휨강도 평가)

  • Won, Kyung-Rok;Oh, Seung-Won;Byeon, Hee-Seop
    • Journal of the Korean Wood Science and Technology
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    • v.42 no.6
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    • pp.723-731
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    • 2014
  • Nondestructive evaluation (NDE) technique method using a resonance frequency mode was carried out for ceramics made by different carbonizing temperatures (600, 800, 1000, $1200^{\circ}C$) after impregnating the phenol resin with Miscanthus sinensis var. purpurascen particle boards. Dynamic modulus of elasticity increased with increasing carbonizing temperature. There were a close relationship of dynamic modulus of elasticity and static bending modulus of elasticity to modulus of rupture (MOR). However, the result indicated that correlation coefficient was higher in dynamic modulus of elasticity to MOR than that in static modulus of elasticity to MOR. Therefore, the dynamic modulus of elasticity using resonance frequency by free vibration mode is more useful as a nondestructive evaluation method for predicting the MOR of ceramics made by different carbonizing temperature for Miscanthus sinensis var. purpurascens particle boards.

Production of Biodiesel from Waste Frying Oil by Transesterification on Zeolite Catalysts with Different Acidity (산성도가 다른 제올라이트 촉매에서 전이에스터화 반응에 의한 폐식용유로부터 바이오디젤 제조)

  • Koh, Tae-Suck;Chung, Kyong-Hwan
    • Applied Chemistry for Engineering
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    • v.19 no.2
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    • pp.214-221
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    • 2008
  • The production of biodiesel by transesterification of waste frying oil was conducted on various zeolite catalysts with different acidity and pore structure. $H^+$ ion exchanged MOR, MFI, FAU, and BEA zeolites were employed in the reaction with silicalite which has no strong acid sites. $H^+$ ion exchanged MOR(10) zeolite, which has more acid sites and stronger acid strength than other zeolites, exhibited the highest methyl esters yield as 95%. Dealumination to the HMOR zeolite induced decreasing of acid amount and acid strength. It brought about the decrease of fatty acid methyl esters (FAME) yield. The yield increased linearly with enhancing of acid strength and increasing of amount of strong acid sites. The yields were independent on pore structure of the zeolites.

Effects of Heating Temperature and Time on the Mechanical Properties of Heat-Treated Woods

  • Won, Kyung-Rok;Hong, Nam-Euy;Park, Han-Min;Moon, Sun-Ok;Byeon, Hee-Seop
    • Journal of the Korean Wood Science and Technology
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    • v.43 no.2
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    • pp.168-176
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    • 2015
  • This study was performed to investigate the effects of heat treatment the on mechanical properties of two species of wood under different heating conditions including at $180^{\circ}C$ for 12 h and 24 h, and at $210^{\circ}C$ for 3 h and 6 h. Two species of wood, Pinus densiflora and Larix kaempferi, were exposed to different heat treatments to assess the effects on the volume change, bending properties in static and dynamic mode and compressive strength. The results showed heat treatment caused significant changes in mechanical properties such as the static and dynamic moduli of elasticity ($MOE_d$ and $MOE_s$), and the modulus of rupture (MOR). The volume of the wood after heat treatment decreased as the heating temperature and time were increased. The bending strength performance of the wood after heat treatment decreased as the heating temperature and time were increased. The effect of heat treatment at a high temperature on the bending MOR was greater in both species than that for a long time. However, the compressive strengths of all the heat-treated samples were higher than the control sample. Furthermore, highly significant correlations between $MOE_d$ and MOR, and $MOE_s$ and MOR were found for all heating conditions.

Effect of sec-O-glucosylhamaudol on mechanical allodynia in a rat model of postoperative pain

  • Koh, Gi-Ho;Song, Hyun;Kim, Sang Hun;Yoon, Myung Ha;Lim, Kyung Joon;Oh, Seon-Hee;Jung, Ki Tae
    • The Korean Journal of Pain
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    • v.32 no.2
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    • pp.87-96
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    • 2019
  • Background: This study was performed in order to examine the effect of intrathecal sec-O-glucosylhamaudol (SOG), an extract from the root of the Peucedanum japonicum Thunb., on incisional pain in a rat model. Methods: The intrathecal catheter was inserted in male Sprague-Dawley rats (n = 55). The postoperative pain model was made and paw withdrawal thresholds (PWTs) were evaluated. Rats were randomly treated with a vehicle (70% dimethyl sulfoxide) and SOG ($10{\mu}g$, $30{\mu}g$, $100{\mu}g$, and $300{\mu}g$) intrathecally, and PWT was observed for four hours. Dose-responsiveness and ED50 values were calculated. Naloxone was administered 10 min prior to treatment of SOG $300{\mu}g$ in order to assess the involvement of SOG with an opioid receptor. The protein levels of the ${\delta}$-opioid receptor, ${\kappa}$-opioid receptor, and ${\mu}$-opioid receptor (MOR) were analyzed by Western blotting of the spinal cord. Results: Intrathecal SOG significantly increased PWT in a dose-dependent manner. Maximum effects were achieved at a dose of $300{\mu}g$ at 60 min after SOG administration, and the maximal possible effect was 85.35% at that time. The medial effective dose of intrathecal SOG was $191.3{\mu}g$ (95% confidence interval, 102.3-357.8). The antinociceptive effects of SOG ($300{\mu}g$) were significantly reverted until 60 min by naloxone. The protein levels of MOR were decreased by administration of SOG. Conclusions: Intrathecal SOG showed a significant antinociceptive effect on the postoperative pain model and reverted by naloxone. The expression of MOR were changed by SOG. The effects of SOG seem to involve the MOR.

Effect of Finger Profile on Static Bending Strength Performance of Finger-Jointed Wood

  • Park, Han-Min;Lee, Gyun-Pil;Kong, Tae-Suk;Ryu, Hyun-Soo;Byeon, Hee-Seop
    • Journal of the Korean Wood Science and Technology
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    • v.32 no.6
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    • pp.57-66
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    • 2004
  • To study the efficient usage of small diameter logs and woods containing defects such as knots, slope of the grain and decay, six types of finger-jointed woods with various finger profiles were made of poplar, pine and oak with different density. We investigated the effect of finger profile on static bending strength performances of finger-jointed woods. The efficiency of bending MOE, MOR and deflection showed the highest value in poplar finger-jointed wood with the lowest density of three species, and the lowest value in oak finger-jointed wood with the highest density of three species. The values markedly decreased with increasing finger pitch for finger-jointed wood glued with polyvinyl acetate (PVAc) resin for all tested species, whereas for the finger-jointed wood glued with resorcinol-phenol formaldehyde (RPF) resin, the influence of finger pitch on the efficiency of MOE was not found in all tested species, and those on the efficiency of MOR and deflection indicated the same trend as finger-jointed wood glued with PVAc resin in the case of pine and oak finger-jointed wood with higher densities. It was found that the values tended to decrease with increasing density of species on the whole and the desirable finger pitches were L (6.8 mm) for poplar, M (4.4 mm) for pine and S (3.5 mm) for oak in a view of economy. For finger-jointed wood glued with PVAc resin, the fitness between a tip and a root width of a pair of fingers δ of 0.5 mm indicated the highest efficiency of MOE for all species. And, the influence of δ on MOR was only found in oak finger-jointed wood glued with RPF resin and the desirable δ value for oak was 0.1 mm. However, it was found that the influence of δ on the strength performance was very small.

The Analysis of Perceived Difference of Market Orientation between Managers and Employees, and Relationship between Market Orientation and Business Performance in Hotel Firms (시장지향성에 대한 관리자와 종업원간, 호텔등급별 지각 차이 및 사업성과의 관계 분석)

  • 이용기;장경란;임종달
    • Asia Marketing Journal
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    • v.2 no.1
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    • pp.27-41
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    • 2000
  • 본 연구는 서비스산업인 호텔기업을 대상으로 특 1 급, 특 2 급, 1 급 호텔의 시장지향성이 관리자와 종업원들간에 어떻게 지각되고, 호텔등급별로 시장지향성은 차이가 있으며, 호텔등급별로 시장지향성이 사업성과에 미치는 영향력은 차이가 있는가를 알아보고자 이에 관련된 연구과제를 설정하고 실증분석 하였다. 본 연구의 실증분석 결과는 다음과 같다. 첫째, 호텔등급별로 관리자와 종업원들은 특 1 급 호텔의 경우 경쟁자의 가격구조에 대한 반응(Moi3)(p<.01)과 시장세분화를 근거로 한 신제품/서비스 개발(Mor1)(p<.05), 특 2 급 호텔의 경우 고객여론 조사 정도(Mog2) (p<.05), 시장세분화를 근거로 한 신제품/서비스 개발(Mor1)(p<.05), 제품/서비스 개발 노력이 고객욕구와 일치하는 가의 정기적 점검 (Mor2)(p<.05)., 1 급 호텔의 경우 비공식적 수단에 의한 호텔산업 정보 수집 정도(Mog3) (p<.05), 사업계획이 시장조사보다는 기술발전에 따라 이루어지는 정도(Mor3)(p<.05) 등의 시장지향성 항목에 대해서 유의적인 지각 차이를 보이는 것으로 나타났다. 둘째, 특 1 급 호텔의 시장지향성이 특 2 급, 1 급 호텔의 시장지향성보다 높은 것으로 나타나 특 2 급, 1 급 호텔은 특 1 급 호텔을 전략적 벤치마킹의 대상으로 설정할 필요성이 있는 것으로 나타났다. 셋째, 호텔등급 별로 시장지향성이 성과에 미치는 영향력(R2)을 분석한 결과, 특 1 급과 특 2 급 호텔이 1 급 호텔에 비하여 유의적으로 높은 것으로 나타났다. 한편 특 1 급과 특 2 급 호텔은 통계적으로 유의적인 차이는 없었으나 특 1 급 호텔의 시장지향성이 더 높은 것으로 나타났다.

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Reaction Mechanism and Curing Characteristics of Chicken Feather-Based Adhesives and Adhesive Properties of Medium-Density Fiberboard Bonded with the Adhesive Resins (닭털로 제조한 접착제의 반응기작 및 경화 특성과 이를 이용하여 제조한 중밀도섬유판의 접착 특성)

  • Yang, In;Park, Dae-Hak;Choi, Won-Sil;Oh, Sei Chang;Ahn, Dong-uk;Han, Gyu-Seong
    • Korean Chemical Engineering Research
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    • v.55 no.3
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    • pp.385-394
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    • 2017
  • In this study, reaction mechanism and curing characteristics of adhesives formulated with NaOH- and $H_2SO_4$-hydrolyzed chicken feather (CF) and formaldehyde-based crosslinkers were investigated by FT-IR and DSC. In addition, adhesive properties and formaldehyde emission of medium-density fiberboards (MDF) applied with the adhesives were measured. CF-based adhesives having a solid content of 40% and over were very viscous at $25^{\circ}C$, but the viscosity reduced to $300{\sim}660m{\cdot}Pa{\cdot}s$ at $50^{\circ}C$. Consequently, the adhesives could be used as a sprayable resin. Through the FT-IR spectra of liquid and cured CF-based adhesives, addition reaction of methylol group and condensation reaction between the functional groups with the use of formaldehyde-based crosslinkers were identified. From the analysis of DSC, it was elucidated for CF-based adhesives to require a higher pressing temperature or longer pressing time comparing to commercial urea-formaldehyde (C-UF) resin. MDF bonded with CF-based adhesives, which was formulated with 5% NaOH-hydrolyzed CF (CF-AK-5%) and PF of formaldehyde to phenol mole ratio of 2.5 (PF-2.5), and pressed for 8 min had higher MOR and IB than those with other CF-based adhesives. MOR and IB of MDF bonded with the CF-based adhesives regardless of formulation type and pressing time were higher than those with C-UF resin. When the values compared with the minimum requirements of KS standard, IB exceeded the KS standard in all formulations and pressing time, but MOR of only MDF bonded with CF-AK-5% and PF-2.5 and pressed for 8 min satisfied the KS standard. What was worse, 24-TS of MDF bonded with all CF-based adhesives did not satisfied the KS standard. However, MOR and 24-TS can be improved by increasing the target density of MDF or the amount of wax emulsion, which is added to improve the water resistance of MDF. Importantly, the use of CF-based adhesives decreased greatly the formaldehyde emission. Based on the results, we reached the conclusion that CF-based adhesives formulated under proper conditions had a potential as a sprayable resin for the production of wood panels.