• International Journal of Advanced Culture Technology
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• v.4 no.4
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• pp.30-37
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• 2016

In this paper, the method of controlling the clock that is inputted on the hardware from the application, and the hardware design method are to be proposed. When the hardware is synthesized to the Field Programmable Gate Array(FPGA), the input clock is fixed, and when the input clock is changed, the synthesis process must be passed again to require more time. To solve this problem, the Mixed-Mode Clock Manager(MMCM) module is mounted to control the MMCM module from the application. The controlled MMCM module controls the input clock of the module. The experiment was process the Neural Network algorithm in the x86 CPU and SIMT based processor mounted the FPGA. The results of the experiment, SIMT-based processors, the time that is processed at a frequency of 50MHz was 77ms, 100MHz was 34ms. There was no additional synthesis time due to a change of the clock frequency.

• IMMUNE NETWORK
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• v.1 no.2
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• pp.170-178
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• 2001

Background: Korean mistletoe (Viscum album) extract has been found to posses immunostimulatory activity. In this study, Korean mistletoe extract, M11C (non-lectin components), was used to know whether this extract might activate mouse peritoneal macrophages to produce interleukin $1{\beta}$ (IL-$1{\beta}$). Methods: Hemagglutination assay was carried out to examine whether M11C contained a lectin or not. To know the effect of M11C on the production of IL-$1{\beta}$, the macrophages were treated by the M11C, and then collected the supernatant (M11C stimulated macrophages-conditioned media; MMCM). MMCM was analyzed for the IL-$1{\beta}$ quantification and mRNA expression by means of ELISA and RT-PCR, respectively. Results: Maximum effective dose and time of M11C on IL-$1{\beta}$ production from macrophages were $20{\mu}g/m{\ell}$ and 8 hours, respectively. This ELISA data was reconfirmed by immunoblotting assay. indicating that M11C is a good candidate for an immunomodulator. The dose and time dependent effects of M11C on the expression of IL-$1{\beta}$ mRNA from macrophages was also shown in expression of mRNA detected by RT-PCR. Treatment dose and time for the maximum expression of IL-$1{\beta}$ mRNA were $20{\mu}g/m{\ell}$ and 4 hours, respectively. Maximum gene expression of IL-$1{\beta}$ was much earlier than maximum production of it. Conclusion: As results, Korean mistletoe extract, M11C, may be used for an immunomodulator. This will be able to make up for and solve the problems caused by existent immunoagent with many adverse effects through many other studies in future including one molecule extraction.