• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9171-9176
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• 2014

Aim: P53, the most commonly mutated tumor suppressor gene in all types of human cancer, is involved in cell cycle arrest and control of apoptosis. Although p53 contains several polymorphic sites, the codon 72 polymorphism is by far more common. There are divergent reports but many studies suggest p53 pro/pro SNP may be associated with susceptibility to developing various cancers in different regions of the world. The present study aimed to find any correlation between H. pylori infection and progression of carcinogenesis, by studying apoptosis and the p53 gene in gastric biopsies from north Indian population. Materials and Methods: A total of 921 biopsies were collected and tested for prevalence of H. pylori by rapid urease test (RUT), imprint cytology and histology. Apoptosis was studied by the TUNEL method. Analysis of p53 gene polymorphism at codon 72 was accomplished by PCR using restriction enzyme BstU1. Observation: Out of 921 samples tested 56.7% (543) were H. pylori positive by the three techniques. The mean apoptotic index (AI) in the normal group was 2.12, while gastritis had the maximum 4.24 followed by gastric ulcer 2.28, gastropathy 2.22 and duodenal ulcer 2.08. Mean AI in cases with gastric cancer (1.72) was less than the normal group. The analysis of p53 72 SNP revealed that p53 (Arg/Arg), (Pro /Arg) variant are higher (40.59% & 33.66%) as compared to p53 pro/pro variant (25.74%) inthe healthy population. Conclusions: The North Indian population harbors Arg or Pro/Arg SNP that is capable of withstanding stress conditions; this may be the reason of low incidence of gastric disease in spite of high infection with H. pylori. There was no significant association with H. pylori infection and AI. However, there is increased apoptosis in gastritis which may occur independent of H. pylori or p53 polymorphism.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.49 no.6
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• pp.473-480
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• 2021

In this paper, We analyze and present improvements to problems in software quality through Static Analysis for Open Source, which is widely used as the Flight Controller software for small unmanned aerial vehicle drones. MISRA coding rules, which are widely applied based on software quality, have been selected. Static analysis tools were used by LDRA tools certified international tools used in all industries, including automobiles, railways, nuclear power and healthcare, as well as aviation. We have identified some safety-threatening problems across the quality of the software, such as structure of open source modules, analysis of usage data, compliance with coding rules, and quality indicators (complexity and testability), and have presented improvements.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.23 no.2
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• pp.243-250
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• 2013

We have entered into an era of smart software system where the many kinds of embedded software, especially SCADA and Automotive software not only require high reliability and safety but also high-security. Removing software weakness during the software development lifecycle is very important because hackers exploit weaknesses which are source of software vulnerabilities when attacking a system. Therefore the coding rule as like core functions of MISRA-C should expand their coding focus on security. In this paper, we used CERT-C secure coding rules for nuclear-related software being developed to demonstrate high-safety software, and proposed how to remove software weakness during development.

• Journal of the Korean Society for Railway
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• v.12 no.1
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• pp.81-87
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• 2009

Recent advances in computer technology have brought more dependency on software to railway signalling system. While much efforts have been reported to evaluate embedded software safety for railway signalling systems, not so much systematic approaches to evaluate software safety testing. In this paper, we propose a adaption of automatic software testing tool in terms of the design & coding standard for railway signalling system. The test items for the design & coding standard suggested in this study related international standards and MISRA-C. It is anticipated that it will be greatly helpful for the evaluation on the software for railway signalling system.

• Journal of Plant Biotechnology
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• v.5 no.4
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• pp.239-244
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• 2003

A protocol has been developed for rapid large scale clonal propagation of an aromatic endangered medicinal plant, Hemidesmus indicus R. Br. with the elimination of the problems such as premature leaf fall and callus formation during caulogenesis and rhizogenesis. Multiple shoots were induced from shoot tip and nodal explants on Murashige and Skoog (MS) medium supplemented with 1 mg/L Benzylaminopurine (BAP) and 0.5 mg/L Napthaleneaceticacid (NAA). Addition of 15 mg/L adenine sulphate to the above medium checked leaf abscission completely, reduced the time required for caulogenesis and restored morphogenetic potential after several subcultures. The in vitro grown propagules were rooted in 1/2 MS medium supplemented with 2 mg/L Indolebutyric acid (IBA) +1 mg/L NAA and sucrose 0.7% (w/v). Addition of charcoal at 100 mg/L to the rooting medium quickened root initiation with a complete check on callus formation. The effect of sucrose concentration on both caulogenesis and rhizogenesis was also studied. The resultant plantlets were acclimatized and grown in fields where ninety eight percent of the rooted shoots survived and grew normally. The estimation of the secondary metabolite content in the shoots of the regenerated plant and the mother plant indicated that the concentration of the three secondary metabolites lupeol, vanillin and rutin was similar.

• Journal of applied mathematics & informatics
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• v.22 no.1_2
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• pp.387-401
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• 2006

This paper deals with the problem of a ratio-dependent prey- predator model with combined harvesting. The existence of steady states and their stability are studied using eigenvalue analysis. Boundedness of the exploited system is examined. We derive conditions for persistence and global stability of the system. The possibility of existence of bionomic equilibria has been considered. The problem of optimal harvest policy is then solved by using Pontryagin's maximal principle.

• Kyungpook Mathematical Journal
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• v.20 no.1
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• pp.37-45
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• 1980

The Riemannian space of recurrent curvature was defined and studied by Ruse [8] and Walker [10]. In 1963, $M{\acute{o}}or$ [4] generalised this idea for Finsler spaces and defined and studied Finsler spaces of recurrent curvature. These spaces for various curvature tensors have subsequently been studied by Mishra and Pande [1], Sen [9] and Misra [3] etc. The purpose of the present paper is to study Finsler space based on the recurrency of the curvature tensors derived from non-linear connections.

• ALGAE
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• v.23 no.1
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• pp.1-14
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• 2008

Forty-eight taxa of desmids belonging to Class Chlorophyceae (Order - Conjugales, Family - Desmidiaceae), collected from different aquatic habitats of Lalkuan, Kathgodam and Pantnagar areas of Uttaranchal state and Pilibheet district of Uttar Pradesh, which are regions of foothills of Western Himalaya, have been described. These taxa belongs to 5 genera viz. Closterium Nitzsch (6 spp., 5 var., and 2 forma), Euastrum Ehrenberg (1 var.), Staurastrum Meyen (2 spp., 1 var., 1 forma), Cosmarium Corda ex Ralfs (19 spp. and 10 var.), Pleurotaenium Naegeli (1 sp.). Staurastrum pseudopachyrhyncum Wolle (1884) is new record for desmid flora of India.

• International Journal of Industrial Entomology and Biomaterials
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• v.6 no.2
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• pp.203-205
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• 2003

Black sooty mould fungus was observed on the upper side of the mulberry leaves caused by the Capnodium sp. This fungus develops with the utilization of the honeydew dropped by the whiteflies. Few selected insecticides like Monocrotophos, Chloropyriphos and Nuvan were tried to control the whitefly incidence and followed by the application of Maida (wheat flour paste) and Starch solution separately to control the incidence of the Capnodium on mulberry. It is found that a significant control of the whitefly incidence with the application of Nuvan (2 $m\ell$/L) and followed by Chloropyriphos (2 $m\ell$/L) and Monocrotophos (1.6 $m\ell$/L) and also a significant control of sooty mould infection were recorded with Starch and Maida application.

• International Journal of Industrial Entomology and Biomaterials
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• v.7 no.1
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• pp.83-86
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• 2003

Mulberry plantations are prone to several kinds of insect pests including the thrips, Pesudodendrothrips mori. The thrips infestation affects the qualitative and quantitative characters of mulberry leaf, which in turn affects the silkworm cocoon crop. In the present study, four commercial insecticides viz., Rogor, Quinalphos, Confidor and Methyl parathion were tested for their efficacy in the control of P. mori thrips. These insecticides were observed to kill 68-80％ within 24 hrs in vivo and 100％ after 12 hrs post-treatment in vitro. Confidor (0.05％) and Quinalphos (0.2％) were most effective in controlling the thrips incidence. The insecticide-sprayed mulberry leaves did not show any adverse effect on the rearing of silkworms.