• 제목/요약/키워드: MIP

검색결과 546건 처리시간 0.028초

Molecularly Imprinted Polymers for Solid-Phase Extraction of Sarcosine as Prostate Cancer Biomarker from Human Urine

  • Hashemi-Moghaddam, Hamid;Rahimian, Majid;Niromand, Bahman
    • Bulletin of the Korean Chemical Society
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    • 제34권8호
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    • pp.2330-2334
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    • 2013
  • A highly selective molecularly imprinted polymer (MIP) for sarcosine, a cancer marker, was prepared and its use as solid-phase extraction (SPE) sorbent material was demonstrated. The MIP was prepared by a very simple procedure using methacrylic acid as functional monomer and a mixture acetonitrile/water (4/1, v/v) as porogen, overcoming in this way the problems usually related to the imprinting of biological polar compounds. The MIP was tested in batch experiments in order to evaluate its binding properties and then used as SPE sorbent for the selective clean-up and pre-concentration of sarcosine. The extraction protocol was successfully applied to the direct extraction of sarcosine from spiked human urine indicating that the MIP allowed sarcosine to be pre-concentrated while simultaneously interfering compounds were removed from the matrix.

조달기간 변동에 따른 EOQ와 OMMIP 비교분석 연구 (The Study for EOQ md OMMIP Comparison Analysis According to Order Lead Time Change)

  • 오세경;최진영
    • 산업경영시스템학회지
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    • 제27권4호
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    • pp.83-89
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    • 2004
  • In this paper MIP(mean inventory period) Model and OMMIP decision flow have been developed. MIP model can calculate mean inventory period which is subject to the order quantity alternative plan. OMMIP decision flow leads how can decide the most minimized order quantity in mean inventory period among various order quantity alternatives. This paper also suggests how to select the order quantity with minimum inventory period as optimal order quantity by means of comparison each mean inventory period with other mean inventory period, after simulating EOQ and order quantity of OMMIP calculated in MIP model.

VVC 행렬가중 화면내 예측(MIP) 학습기법 분석 (Analysis of Training Method for Matrix Weighted Intra Prediction (MIP) in VVC)

  • 박도현;권형진;정세윤;김재곤
    • 한국방송∙미디어공학회:학술대회논문집
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    • 한국방송∙미디어공학회 2020년도 추계학술대회
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    • pp.148-150
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    • 2020
  • 최근 VVC(Versatile Video Coding) 표준 완료 이후 JVET(Joint Video Experts Team)은 인공신경망 기반의 비디오 부호화를 위한 AhG(Ad-hoc Group) 구성하고 인공지능을 이용한 비디오 압축 기술들을 검증하고 있으며, MPEG(Moving Picture Experts Group)에서는 DNNVC(Deep Neural Network based Video Coding) 활동을 통해 딥러닝 기반의 차세대 비디오 부호화 표준 기술을 탐색하고 있다. 본 논문은 VVC 에 채택된 신경망 기반의 기술인 MIP(Matrix Weighted Intra Prediction)를 참조하여, MIP 모델의 학습에서 손실함수가 예측 성능에 미치는 영향을 분석한다. 즉, 예측의 왜곡(MSE)만을 고려한 경우와 예측오차의 부호화 비용도 함께 반영한 손실함수를 비교한다. 실험을 위해 HEVC(High Efficiency Video Coding) 화면내 예측 대비 평균적인 PSNR 향상 정도를 나타내는 성능 지표(��PSNR)를 정의한다. 실험결과 예측오차의 부호화 특성을 반영하는 손실함수를 이용한 학습이 MSE 만 고려한 학습 대비 ��PSNR 기준 평균 0.4dB 향상됨을 보였다.

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완전연결계층 기반의 다중 모델을 이용한 화면내 예측 (Intra Prediction Using Multiple Models Based on Fully Connected Layer)

  • 김민재;문기화;박도현;권형진;김재곤
    • 한국방송∙미디어공학회:학술대회논문집
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    • 한국방송∙미디어공학회 2021년도 하계학술대회
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    • pp.355-356
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    • 2021
  • 딥러닝 기술과 하드웨어의 발전으로 다양한 분야에서 인공신경망과 관련한 연구가 활발히 진행되고 있다. 비디오 코덱 부분에서도 딥러닝 기술을 적용하는 부호화 기술이 많이 연구되고 있다. 본 논문은 최근 완료된 VVC 에 채택된 신경망 기반의 기술인 MIP(Matrix Weighted Intra Prediction)를 확장하여 보다 깊은 계층의 모델로 학습된 새로운 화면내 예측 모델을 제안한다. 기존 VVC 의 MIP 의 성능과 비교하기 위하여 기존 MIP 모델과 제안하는 다중완전연결계층(Fully Connected Layer) 화면내 예측 모델을 HEVC(High Efficiency Video Coding)에 적용하여 그 성능을 비교하였다. 실험결과 제안기법은 VVC MIP 대비 0.08 BD-rate 성능 향상을 보였다.

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PTSA를 이용한 IMS 기반 PMIP의 효율적인 핸드오버 기법 (An efficient handover scheme for PMIP based on IMS using PTSA)

  • 최민석;이현철;윤희용
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2008년도 추계학술발표대회
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    • pp.1340-1343
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    • 2008
  • 최근 인터넷기반의 멀티미디어 서비스의 발전에 힘입어 기존의 IP망을 코어 네트워크로 사용하는 이종망간의 통합서비스가 주를 이루고 있다. 이에 따른 사용자들의 요구로 고품질 멀티미디어 데이터 서비스 지원의 QoS와 멀티미디어 서비스를 끊김없는 이동성(Seamless Mobility)에 대해서 지원할 수 있는 핸드오버기법이 필수적이게 되었다. 이중 끊김없는 이동성 지원하기 위해 MIP(Mobile IP)기법이 제안되었고, 이를 향상시킨 FMIP(Fast Handover for. MIP), HMIP(Hierarchical MIP) 그리고 PMIP(Proxy MIP)까지 제안되었다. 본 논문에서는 IMS망의 P-CSCF의 SIP프로토콜과 PMIP핸드오버 기법을 연동하는 PTSA(PMIP To SIP Agent)를 두어 IMS망에서 적용할 수 있는 향상된 PMIP 핸드오버 기법을 제안한다.

LPS로 유발된 마우스 대식세포의 케모카인류 염증인자 생성에 미치는 백삼이중탕 및 홍삼이중탕의 영향비교 (Effect of White Ginseng-Ejung-tang and Red Ginseng-Ejung-tang Water Extract on Production of Chemokines and IL-21 in LPS-induced RAW 264.7 Mouse Macrophages)

  • 박완수
    • 동의생리병리학회지
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    • 제27권6호
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    • pp.795-801
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    • 2013
  • The purpose of this study is to investigate effects of White Ginseng-Ejung-tang (EG) and Red Ginseng-Ejung-tang (ER) water extract on production of various cytokines such as interleukin (IL)-21, IL-25, IL-$28{\beta}$, erythropoietin (EPO), Exodus-2, monocyte chemotactic protein (MCP)-5, macrophage inflammatory protein (MIP)-$3{\alpha}$, MIP-$3{\beta}$, Fractalkine, and TARC in RAW 264.7 mouse macrophages stimulated by lipopolysaccharide (LPS). Levels of cytokines were measured by High-throughput multiplex bead array cytokine assay based on xMAP (multi-analyte profiling beads) technology. ER significantly decreased levels of IL-21, IL-25, IL-$28{\beta}$, EPO, Exodus-2, MCP-5, MIP-$3{\alpha}$, MIP-$3{\beta}$, TARC, and fractalkine for 24 h incubation at the oncentrations of 25 and 100 ${\mu}g/mL$ in LPS-induced RAW 264.7 (P < 0.05). But EG did not show any significant effect. These results suggest that ER has anti-inflammtory property related with its inhibition on the production of IL-21, IL-25, IL-$28{\beta}$, and chemokines such as EPO, MCP-5, MIP-$3{\alpha}$, MIP-$3{\beta}$, Fractalkine, Exodus-2, and TARC in LPS-induced macrophages.

진폐 정밀/요양기관과 요양기관의 흉부 방사선분야 정도관리 비교 (Comparison of Quality Control for Chest Radiography between Special Examination and Medical Institution for Pneumoconiosis)

  • 이원정
    • 한국콘텐츠학회논문지
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    • 제11권2호
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    • pp.322-330
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    • 2011
  • 전국 33개 진폐요양기관 흉부 방사선분야 정도관리 실태조사를 실시하여 정밀/요양기관(17개)과 요양기관(16개)에 대해 산업안전보건연구원 진폐정도관리 평가표를 이용하여 촬영기술, 판독환경 및 화질평가 결과를 비교 분석하였다. 촬영기술과 판독환경은 연구자가 직접방문하여 평가하였고, 화질평가는 각 진폐 요양기관에서 보내온 영상을 기관마다 10장씩 무작위추출하여 2명의 흉부 영상의학과 전문의가 영상에 대한 어떤 정보도 모르는 상태에서 개별적으로 실시하였다. 정밀/요양기관과 요양기관 사이, 흉부 방사선 촬영 장치의 성능, 사용기간, 촬영방법에서는 유의한 차이가 없었지만, 단순 흉부 촬영조건에서 관전압과 그리드 비에서 유의한 차이가 있었다. 또한, 촬영기술과 판독환경평가에서는 정밀/요양기관이 요양기관 보다 유의하게 높았고, 화질평가에서도 높았지만 유의한 차이는 없었다. 따라서, 진폐합병증이 있는 요양환자의 신뢰성있고 정확한 진단을 위해서는 요양기관의 흉부 방사선분야 정도관리 향상을 위한 외부평가 및 교육이 필요하다.

Effectiveness of Multi Interventional Package on Selected Parameters of Metabolic Syndrome among Women - A Pilot Study

  • Elizabeth, Attonassary Jose;Aruna, Swaminathan;Mercy, Parayidathil Joseph
    • 대한간호학회지
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    • 제50권4호
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    • pp.523-532
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    • 2020
  • Purpose: The purpose of the study was to compare the effectiveness of multi interventional package (MIP) and lifestyle interventions (LI) on physiological parameters of women with metabolic syndrome, to compare the effectiveness of MIP and LI on biochemical parameters of women with metabolic syndrome and to compare the effectiveness of MIP and LI on socio-psychological parameters of women with metabolic syndrome. Methods: A quasi experimental nonequivalent control group design with two experimental groups and one control group was used to collect data from 60 self-help group women. Samples were selected by multistage sampling. Reflexology foot massage, dietary modification, moderate intensity exercise and structured education were given to MIP group and dietary modification, moderate intensity exercise and structured education were given to LI group for 12 weeks. Control group received routine care. Demographic and clinical data sheets were used to collect basic information. Knowledge was assessed by a knowledge questionnaire. Physiological (weight, body mass index, waist circumference and blood pressure) and biochemical parameters (HDL, triglycerides and FBS) were assessed before and after the intervention. Results: The study found significant change in the physiological and biochemical parameters of metabolic syndrome as well as knowledge among the MIP group and LI group compared to the control group (p <.001). Conclusion: MIP and LI are effective in controlling the parameters of metabolic syndrome. Hence the guidance may be provided to women with metabolic syndrome for adopting necessary lifestyle changes as well as reflexology foot massage to control the physiological and biochemical parameters of metabolic syndrome.

Comparison of the effects of different-sized airways in inspiratory trainers on maximal inspiratory pressure and rating of perceived exertion scale in healthy young people

  • Hwang, Young-In;Kim, Ki-Song
    • Physical Therapy Rehabilitation Science
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    • 제7권1호
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    • pp.18-22
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    • 2018
  • Objective: This study aimed to investigate the effect of different-sized airways of the inspiratory muscle trainer (IMT) on maximal inspiratory pressure (MIP) and the rating of perceived exertion, as measured by the modified Borg scale (m-Borg). Design: Cross-sectional study. Methods: Twenty healthy subjects (10 men, 10 women) volunteered for the study. The spirometry was used to measure MIP. The trial order of the three spirometry conditions was chosen randomly. After measuring the MIP and before taking the final break, each of the conditions were immediately measured using the m-Borg. All subjects used the IMT with an airway diameter of 5-, 6-, and 7-mm. Results: The MIP significantly decreased with the decreasing airway diameter of the IMT (p<0.001), and the differences in all three conditions (7- and 6-mm, 6- and 5-mm, and 7- and 5-mm airways) were significant (p<0.05). The RPE significantly increased with the decreasing airway diameter of the IMT (p<0.001), and the differences in all three conditions (7- and 6-mm, 6- and 5-mm, and 7- and 5-mm airways) were significant (p<0.05). Conclusions: Decreasing the airway diameter of the IMT decreased the MIP and increased the m-Borg. In regards to physical exercise within the clinical setting, the m-Borg could be a useful as a prior monitoring method to prevent dyspnea for patients with narrowed airways (blocked with secretion or sputum in pulmonary disease) and the different-sized airways of the IMT could be applied as a useful tool to improve MIP for prevention of pulmonary disease.

소청용장(小靑龍湯)이 생쥐의 폐(肺) 대식세포(大食細胞) Cytokine 귀전자(遣傳子) 발현에 미치는 영향 (Effects of Sochungyong-tang on Cytokine Gene Expression in Mouse Alveolar Macrophage)

  • 박인기;심성용;변학성;김경준
    • 한방안이비인후피부과학회지
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    • 제18권3호
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    • pp.1-17
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    • 2005
  • In many recent studies, molecular biological methods have been used to investigate the role of cytokines in pathogenesis of lung disease. This Experiment was conducted to investigate the effects of Sochungyong-tang on gene expressions in Mouse Alveolar Macrophage. Fer this purpose, we observed the cytokines ($IL-1{\beta}$, IL-6, IL-10, iNOS, $MIP-1{\alpha},\;MIP-1{\beta},\;MIP-1{\gamma},\;TGF-{\beta},\;TNF-{\alpha}$). We picked the alveolar macrophage out of mice and cultured it. We analyzed the cytokine gene expression by reverse transcription-PCR. The results obtained were as follows : 1 . Sochungyong-tang showed inhibitory effects on $IL-1{\beta}$ in time and concentration. 2. Sochungyong-tang showed inhibitory effects on IL-6 in time and concentration. 3. Sochungyong-tang showed inhibitory effects on IL-10 in concentration. 4. Sochungyong-tang showed inhibitory effects on iNOS. 5. Sochungyong-tang showed inhibitory effects on $TGF-{\beta}$ in time and concentration. 6. Sochungyong-tang showed on inhibitory effects on $MIP-1{\alpha},\;MIP-1{\beta},\;MIP-1{\gamma}$, $TCF-{\beta}$, $TNF-{\alpha}$. According to above results, it is supposed that Sochungyong-tang has the inhibitory effects on cytokine gene expression in mouse alveolar macrophage and can be usefully applied for curing inflammatory process of lung disease. Advanced studies are required to investigate the cure mechanism of Sochungyong-tang in the future.

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