• Title/Summary/Keyword: MIMICS

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A Rare Case of Küttner Tumor Originating from Submandibular Gland (악하선에 발생한 Küttner 종양 1예)

  • Choi, Byeong Il;Kang, Min Seok;Kim, Min Ki;Lim, Beom Jin;Byeon, Hyung Kwon
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.2
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    • pp.66-69
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    • 2015
  • $K{\ddot{u}}ttner$ tumor is a benign inflammatory disease of the salivary gland that clinically mimics a malignant tumor because of its presentation as a unilateral painless hard mass. However the precise cause of this disease is still unknown. Pathologically, it is characterized by infiltration of IgG4-positive plasma cells. Also, it is accompanied with an elevated level of plasma IgG4. We report one case of $K{\ddot{u}}ttner$ tumor of the right submandibular gland in a 37 year old woman.

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Development of Dental Chewing Masticator (치과용 저작 매스티케이터의 개발)

  • Lee, Kwon-Yong;Jung, Il-Young;Park, Sung-Ho;Jeon, Seung-Beom
    • Proceedings of the Korean Society of Tribologists and Lubrication Engineers Conference
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    • 2002.05a
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    • pp.255-258
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    • 2002
  • Dental chewing masticator, which is an essential device for evaluating the wear of dental resin and the interfacial failure between the filling resin and enamel of tooth used in conservative dentistry, was developed. This dental chewing masticator mimics the chewing motion and loading by adapting DC motor and rotary cam system. Chewing loading of 49N was imposed by computer-displacement control, loadcell, LM guide, and spring system. Extracted tooth was fixed into a holding jig, and this jig was mounted with rubber pad on the $15^{\circ}$inclined surface to consider the lateral movement of periodontal ligament. A water bath was installed for providing the environment of inside mouth and for circulating the $5^{\circ}C-55^{\circ}C$ water to evaluate the effect of hydrothermal cycling on the damage of resin filled teeth during long-term chewing activity.

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Impact Bending Test Simulations of FH32 High-strength Steel for Arctic Marine Structures

  • Choung, Joonmo;Han, Donghwa;Noh, Myung-Hyun;Lee, Jae-Yik;Shim, Sanghoon
    • Journal of Advanced Research in Ocean Engineering
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    • v.2 no.1
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    • pp.28-39
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    • 2016
  • This paper provides theoretical and experimental results to verify the crashworthiness of FH32 high-strength steel for arctic marine structures against ice impact. Assuming that side-shell structures of the Korean arctic research vessel, ARAON, with ice-notation PL10, collide with sheet ice, one-third-scale test specimens with a single transverse frame are manufactured. Impact-bending tests were conducted using a rigid steel striker that mimics sheet ice. Drop height was calculated by considering the speed at which sheet ice is rammed. Prior to impact-bending tests, tensile coupon tests were conducted at various temperatures. The impact-bending tests were carried out using test specimens fully fixed to the inside bottom frame of a cold chamber. The drop-weight velocity and test specimen deformation speed were measured using a high-speed camera and digital image correlation analysis (DICA). Numerical simulations were carried out under the same conditions as the impact-bending tests. The simulation results were in agreement with the test results, and strain rate was a key factor for the accuracy of numerical simulations.

Sound Improvement of Violin Playing Robot Applying Auditory Feedback

  • Jo, Wonse;Yura, Jargalbaatar;Kim, Donghan
    • Journal of Electrical Engineering and Technology
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    • v.12 no.6
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    • pp.2378-2387
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    • 2017
  • Violinists learn to make better sounds by hearing and evaluating their own playing though numerous practice. This study proposes a new method of auditory feedback, which mimics this violinists' step and verifies its efficiency using experiments. Making the desired sound quality of a violin is difficult without auditory feedback even though an expert violinist plays. An algorithm for controlling a robot arm of violin playing robot is determined based on correlations with bowing speed, bowing force, and sound point that determine the sound quality of a violin. The bowing speed is estimated by the control command of the robot arm, where the bowing force and the sound point are recognized by using a two-axis load cell and a photo interrupter, respectively. To improve the sound quality of a violin playing robot, the sounds information is obtained by auditory feedback system applied Short Time Fourier Transform (STFT) to the sounds from a violin. This study suggests Gaussian-Harmonic-Quality (GHQ) uses sounds' clarity, accuracy, and harmonic structure in order to decide sound quality, objectively. Through the experiments, the auditory feedback system improved the performance quality by the robot accordingly, changing the bowing speed, bowing force, and sound point and determining the quality of robot sounds by GHQ sound quality evaluation system.

Stress-induced Cardiomyopathy during Pulmonary Resection (Takotsubo Syndrome) - A case report -

  • Lee, Seok-Kee;Lim, Seung-Pyung;Yu, Jae-Hyeon;Na, Myung-Hoon;Kang, Shin-Kwang;Kang, Min-Woong;Oh, Hyun-Kong
    • Journal of Chest Surgery
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    • v.44 no.4
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    • pp.294-297
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    • 2011
  • Stress-induced cardiomyopathy is caused by emotional or physical stressors and mimics acute myocardial infarction, though Stress-induced cardiomyopathy is characterized by reversible left ventricular (LV) apical ballooning in the absence of significant coronary artery disease. We describe a 51-year-old male who underwent left upper lobectomy for non-small cell lung cancer, and during which cardiogenic arrest occurred due to stress-induced cardiomyopathy, successfully managed by intra-aortic balloon pumping and extracorporeal membrane oxygenation.

A study on the optimal sizing and topology design for Truss/Beam structures using a genetic algorithm (유전자 알고리듬을 이용한 트러스/보 구조물의 기하학적 치수 및 토폴로지 최적설계에 관한 연구)

  • 박종권;성활경
    • Journal of the Korean Society for Precision Engineering
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    • v.14 no.3
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    • pp.89-97
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    • 1997
  • A genetic algorithm (GA) is a stochastic direct search strategy that mimics the process of genetic evolution. The GA applied herein works on a population of structural designs at any one time, and uses a structured information exchange based on the principles of natural selection and wurvival of the fittest to recombine the most desirable features of the designs over a sequence of generations until the process converges to a "maximum fitness" design. Principles of genetics are adapted into a search procedure for structural optimization. The methods consist of three genetics operations mainly named selection, cross- over and mutation. In this study, a method of finding the optimum topology of truss/beam structure is pro- posed by using the GA. In order to use GA in the optimum topology problem, chromosomes to FEM elements are assigned, and a penalty function is used to include constraints into fitness function. The results show that the GA has the potential to be an effective tool for the optimal design of structures accounting for sizing, geometrical and topological variables.variables.

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A Study on Motion Planning Generation of Jumping Robot Control Using Model Transformation Method (모델 변환법을 이용한 점핑 로봇 제어의 운동경로 생성에 관한 연구)

  • 서진호;산북창의;이권순
    • Journal of the Korean Society for Precision Engineering
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    • v.21 no.4
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    • pp.120-131
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    • 2004
  • In this paper, we propose the method of a motion planning generation in which the movement of the 3-link leg subsystem is constrained to a slider-link and a singular posture can be easily avoided. The proposed method is the jumping control moving in vertical direction which mimics a cat's behavior. That is, it is jumping toward wall and kicking it to get a higher-place. Considering the movement from the point of constraint mechanical system, the robotic system which realizes the motion changes its configuration according to the position and it has several phases such as; ⅰ) an one-leg phase, ⅱ) in an air-phase. In other words, the system is under nonholonomic constraint due to the reservation of its momentum. Especially, in an air-phase, we will use a control method using state transformation and linearization in order to control the landing posture. Also, an iterative learning control algorithm is applied in order to improve the robustness of the control. The simulation results for jumping control will illustrate the effectiveness of the proposed control method.

Development of the Mammalian Expression Vector System that can be Induced by IPTG and/or Lactose

  • Myung, Seung-Hyun;Park, Junghee;Han, Ji-Hye;Kim, Tae-Hyoung
    • Journal of Microbiology and Biotechnology
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    • v.30 no.8
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    • pp.1124-1131
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    • 2020
  • Techniques used for the regulation of gene expression facilitate studies of gene function and treatment of diseases via gene therapy. Many tools have been developed for the regulation of gene expression in mammalian cells. The Lac operon system induced with isopropyl β-D-1-thiogalactopyranoside (IPTG) is one of the employed inducible systems. IPTG mimics the molecular structure of allolactose and has a strong affinity for the corresponding repressor. IPTG is known to rapidly penetrate into mammalian cells and exhibits low toxicity. In the present study, we developed a new inducible expression system that could regulate the expression of genes in mammalian cells using IPTG. Here we confirm that unlike other vector systems based on the Lac operon, this expression system allows regulation of gene expression with lactose in the mammalian cells upon transfection. The co-treatment with IPTG and lactose could improve the regulatory efficiency of the specific target gene expression. The regulation of gene expression with lactose has several benefits. Lactose is safe in humans as compared to other chemical substances and is easily available, making this technique very cost-effective.

Computational modeling of the atmospheric boundary layer using various two-equation turbulence models

  • Juretic, Franjo;Kozmar, Hrvoje
    • Wind and Structures
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    • v.19 no.6
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    • pp.687-708
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    • 2014
  • The performance of the $k-{\varepsilon}$ and $k-{\omega}$ two-equation turbulence models was investigated in computational simulations of the neutrally stratified atmospheric boundary layer developing above various terrain types. This was achieved by using a proposed methodology that mimics the experimental setup in the boundary layer wind tunnel and accounts for a decrease in turbulence parameters with height, as observed in the atmosphere. An important feature of this approach is pressure regulation along the computational domain that is additionally supported by the nearly constant turbulent kinetic energy to Reynolds shear stress ratio at all heights. In addition to the mean velocity and turbulent kinetic energy commonly simulated in previous relevant studies, this approach focuses on the appropriate prediction of Reynolds shear stress as well. The computational results agree very well with experimental results. In particular, the difference between the calculated and measured mean velocity, turbulent kinetic energy and Reynolds shear stress profiles is less than ${\pm}10%$ in most parts of the computational domain.

MiR-323-5p acts as a Tumor Suppressor by Targeting the Insulin-like Growth Factor 1 Receptor in Human Glioma Cells

  • Lian, Hai-Wei;Zhou, Yun;Jian, Zhi-Hong;Liu, Ren-Zhong
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10181-10185
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    • 2015
  • Background: MicroRNAs, small noncoding RNA molecules, can regulate mammalian cell growth, apoptosis and differentiation by controlling the expression of target genes. The aim of this study was to investigate the function of miR-323-5p in the glioma cell line, U251. Materials and Methods: After over-expression of miR-323-5p using miR-323-5p mimics, cell growth, apoptosis and migration were tested by MTT, flow cytometry and cell wound healing assay, respectively. We also assessed the influence of miR-323-5p on the mRNA expression of IGF-1R by quantitative real-time reverse transcriptase PCR (qRT-PCR), and on the protein levels by Western blot analysi. In addition, dual-luciferase reporter assays were performed to determine the target site of miR-323-5p to IGF-1R 3'UTR. Results: Our findings showed that over-expression of miR-323-5p could promote apoptosis of U251 and inhibit the proliferation and migration of the glioma cells. Conclusions: This study demonstrated that increased expression of miR-323-5p might be related to glioma progression, which indicates a potential role of miR-323-5p for clinical therapy.