• Journal of Life Science
• /
• v.19 no.8
• /
• pp.1009-1015
• /
• 2009

The beneficial use of sedatives is often required for medically ill patients. This study examined the effect of plant flavonoids and diazepam peripheral-type benzodiazepine receptor (PBR) activation and glucose utilization in breast cancer cells, along with their interactions. In estrogen receptor negative MDA-MB-231 cells, the anti-proliferative activity of fisetin (3,7,3',4'-tetrahydroxyflavone) and diazepam was more prominent than in estrogen receptor positive MCF-7 cells. Unlike PBR ligands, treatment with $10^{-6}$ M concentration of diazepam for 3 days exhibited anti-proliferative effects, while similar to apigenin (4',5,7-Trihydroxyflavone) and fisetin, diazepam hardly affected the PBR mRNA expression by MDA-MB-231 cells. Treatment with $10^{-6}$ M concentration of flavonoids and diazepam for 3 days inhibited the glucose utilization of MDA-MB-231 cells. Treatment with $10^{-6}$ M concentration of flavonoids and diazepam for 6 days showed increased cytotoxicity and reduced the PBR mRNA expression of the MDA-MB-231 cells. Apigenin enhanced diazepam-induced anti-proliferative effects on the MDA-MB-231 cells as well. All together, this study showed the in vitro anti-proliferative activity of flavonoids and diazepam on MDA-MB-231 breast cancer cells, plus additive enhancements. In conclusion, this study provides experimental basis for advanced trials in the future.

• Korean Journal of Food Science and Technology
• /
• v.38 no.1
• /
• pp.82-87
• /
• 2006

Twenty one strains strongly producing protease were isolated from Korean traditional Cheonggukjang. Eight strains selected by sensory evaluation on Cheonggukjang prepared with isolated strains were identified with based on biochemical properties a and 16S rDNA sequencing. Identified strains were Bacillus subtilis MB4, and Bacillus amyloliquefaciens A1, A2, B1, MC1, SB2, SC1, and SD1. Protease activities, important strain selection factor, were higher in Cheongjukjang prepared with B. subtilis MB4 (179.6 Unit) and B. amyloliquefaciens SB2 (201.9 Unit) than commercial traditional Cheonggukjang (97.9 Unit). Sensory evaluation revealed Cheonggukjang prepared with B. subtilis MB4 had flavor very similar to commercial traditional Cheonggukjang. Cheonggukjang prepared with B. suhtilis MB4 (0.0006 Pa s) and commercial traditional Cheonggukjang (0.0002 Pa s) revealed lower viscosities than those of Cheonggukjang prepared with B. amyloliquefaciens SB2, MC1, B1, A1, SD1, A2, and SC1 (0.006 to 0.008 Pa s at 1001/s. Results show Cheonggukjang could be prepared using single strain of B. subtilis MB4, maintaining high protease activity and very similar sensory and viscosity qualities with those of commercial traditional Cheonggukjang.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.33 no.8C
• /
• pp.613-616
• /
• 2008

In this paper, a fine residual frequency offset estimation scheme is proposed for multiband orthogonal frequency division multiplexing ultra-wideband (MB-OFDM UWB) systems. The basic idea of our approach is based on the fact that two adjacent OFDM symbols carry the identical information in the MB-OFDM UWB system, thus removing the need of pilot symbols. The mean square error of the synchronization scheme is evaluated and simulation results are used to verify the effectiveness of the proposed estimator. When compared to the pilot-aided conventional estimator, the proposed estimator has a lower estimation error.

• Proceedings of the Korea Multimedia Society Conference
• /
• 2000.11a
• /
• pp.549-552
• /
• 2000

본 논문은 웹 기반 네트워크 관리 시스템 WNMS(Web-based Network Management System)에 대한 설계 및 구현에 대해 기술한다. WNMS는 크게 네트워크 구성 관리, MIB(Management Information Base: 이하 MIB ) Browser, 그리고 트래픽 모니터링 기능을 갖는다. 네트워크 구성 관리는 관리 서버가구동 되면, 네트워크들과 네트워크 장비들을 찾는다. 이는 관리자에게 전체적인 네트워크 구성을 한눈에 쉽게 파악할 수 있게 한다. MIB Browsers 는 관리자가 직접 SNMP 에이전트의 특정한 관리정보(MIB 노드 값)를 검색 또는 조작할 수 있게 한다. 그리고 트래픽 모니터링은 구성 관리에서 찾아진 네트워크나 네트워크 장비의 트래픽을 실시간으로 그래프로 보여준다

• Proceedings of the Korean Society of Computer Information Conference
• /
• 2023.01a
• /
• pp.405-406
• /
• 2023

일반적으로 네트워크 장비는 원활한 장비 관리를 위해 SNMP라는 프로토콜을 활용한다. SNMP를 활용함에 있어, 각 장비 제조사에서는 고유 기능을 정의하여 사용하기도 하는데 이를 Private MIB이라고 한다. 본 연구에서는 이러한 Private MIB을 대상으로 하는 퍼징(Fuzzing) 기술을 고안하였다. 본 논문에서는 특정 제조사의 Private MIB에 대해 페이로드를 만드는 전략과 실제 페이로드의 생성을 보인다. 이는 수많은 소프트웨어 혹은 장비들의 초기 안전성 평가를 수행하는 데 응용될 수 있을 것으로 기대한다.

• Horticultural Science & Technology
• /
• v.16 no.3
• /
• pp.374-376
• /
• 1998

Effects of traditional fumigation (methyl bromide; MB) and combined fumigation (methyl bromide/phosphide; $MB/PH_3$) on the disinfestation, and phytotoxicity and longevity of cut flowers (lily and rose) were investigated. Combined fumigation with low concentrations of $7/3g/m^3\;(MB/PH_3$) at $10^{\circ}C$ immediately after transportation from harvested place was found to be much more effective in disinfestation of aphid, mite, and thrips than fumigation with $MB\;48g/m^3$ only at $20^{\circ}C$ after simulated transportation for 2 days. Quality and longevity of cut flowers measured after fumigation were better in flowers treated by combined fumigation ($7/3g/m^3,\;MB/PH_3$) at $10^{\circ}C$ for 2.5-3 hrs, irrespective of pretreatment with pulsing solution immediately after transporation, even though phytotoxicity varied with cut flowers fumigated. On the other hand, fumigation with $MB\;48g/m^3$ only at $20^{\circ}C$ after simulated transportation for 2 days showed tendency of enhanced insect disinfestation, but caused phytotoxicity to both lily and rose, regardless of pretreatment and moreover, reduced the longevity of the cut flowers.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.40 no.6
• /
• pp.912-917
• /
• 2011

The sterilization efficacies of various washing solutions on the surfaces of vegetables such as sesame leaves, lettuce, and mini-cabbage were investigated. The washing solutions were tap water (TW), microbubble water (MB), electrolyzed water (EW), and microbubble electrolyzed water (MB＋EW). After Escherichia coli and Bacillus cereus were artificially inoculated onto the surfaces of vegetables, each vegetable was washed for 1, 3, and 5 min with TW, MB, EW 100 (100 mg/L of available chlorine), EW 200 (200 mg/L of available chlorine), MB+EW 100, and MB＋EW 200. The washing efficacy of MB was slightly higher than that of TW, and EW was more effective than MB (p<0.05). In all instances, the sterilization efficacies of MB+EW 100 and MB+EW 200 were higher than those of EW 100 and EW 200 (p<0.05). Thus, MB+EW offers an effective means of reducing the studied microorganisms in a short time period. The MB＋EW washing method provides microbial reduction on the surfaces of various vegetables and enhances the microbiological safety of the vegetables.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.16 no.11 s.102
• /
• pp.1075-1085
• /
• 2005

The purpose of this paper is to design the architecture for synchronization of MB-OFDM UWB system that is being processed the standardization for Alt-PHY of WPAN(Wireless Personal Area Network) at IEEE802.15.3a and to analyze the implementation loss due to 4 parallel synchronization architecture for design or link margin. First an overview of the MB-OFDM UWB system based on IEEE802.15.3a Alt-PHY standard is described. The effects of non-ideal transmission conditions of the MB-OFDM UWB system including carrier frequency offset and sampling clock offset are analyzed to design a full digital architecture for synchronization. The synchronization architecture using 4-parallel structure is then proposed to consider the VLSI implementation including algorithms for carrier frequency offset and sampling clock offset to minimize the effects of synchronization errors. The overall performance degradation due to the proposed synchronization architecture is simulated to be with maximum 3.08 dB of the ideal receiver in maximum carrier frequency offset and sampling clock offset tolerance fir MB-OFDM UWB system.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.28 no.7C
• /
• pp.726-732
• /
• 2003

The paper proposes a motion estimation (ME) technique to reduce computational complexity. It is achieved by skipping ME process for macro-blocks decided to be in no need of the operation. Thus, it is called ME skipping technique(MEST). In general, the ME is composed of integer pixel precision ME (IME) followed by half pixel precision ME (HME). The MEST is performed just before an IME process and makes a decision on skipping the IME process according to a criterion based on ME errors of adjacent macro-blocks (MBs) already encoded. When the IME process for a MB is decided to be skipped, which is called ME skip mode, the IME process is skipped and the integer pixel precision motion vector of the MB is just replaced by a predicted vector and used as the input of HME. On the other hands, the IME processes for MBs in ME non-skip mode are not skipped but normally performed. Accordingly, the MEST is very effective to reduce computational complexity when MBs in ME skip mode is abundant. In addition, when the MEST is applied to video encoder, it contributes to more accurate rate control and more robusaess for channel errors. It is experimentally shown that the MEST has the above advantages while maintaining good reconstructed image quality.

• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.15 no.10
• /
• pp.829-841
• /
• 1990

On assuming that the transmission speed of the original information is the fifth-order transmission speed of the Korea digital multiplex hierarchy (564.992Mb/s), this paper proposes a new structure of the transmission line frame at the terminal repeater system, in order to not only maintain and conserve 565Mb/s optical fiber transmission system but also make the B.S.I. of digital communication network for the optical transmission. And the structure uses the mBIZ transmission line code, which is considered the optimal transmission line code of conventional transmission line codes. System hardware of the transmission line frame structure proposed in this paper is consisted by a method of pulse stuffing after converting the speed of the original information signal sequence at the terminal repeater system for 565Mb/s optical transmission. As a result of this, we can prevent the optical transmission system from a domino phenomenon, the phenomenon of the continuous error multiplication of systems by the transmission error, and suppress timing jitter and the identical consecutive digit number. And also we can improve SNR of the optical transmission system about 2dB because of raising total BER at the optical terminal system up to 10.