• Title/Summary/Keyword: MI complex

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A considerable review on type specimens of Korean vascular plants in the Herbarium of the Komarov Botanical Institute (LE) Addition

  • Grabovskaya-Borodina, Alisa E.;Illarionova, Irina D.;Jang, Hyun-Do;Lee, Byoungyoon;Suh, Min Hwan;Park, Jeong Mi
    • Journal of Species Research
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    • v.7 no.1
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    • pp.73-79
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    • 2018
  • The review provides the information about 46 type specimens on 35 taxa of vascular plants from Korea (Fig. 1), kept in the Herbarium of the Komarov Botanical Institute of the Russian Academy of Sciences in addition to 150 taxa published before. Lectotype of Ligustrum patulum Palib is designated here.

Electrical Characteristics of Poly(ethylene oxide)-urea Complex Films

  • Cho, Mi-Yeon;Cho, Kyoung-Ah;Kim, Sang-Sig
    • Transactions on Electrical and Electronic Materials
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    • v.13 no.3
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    • pp.136-138
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    • 2012
  • The electrical characteristics of complex films composed of poly(ethylene oxide) (PEO) and urea as a function of the urea concentration were examined in this study. Moreover, their structural characteristics were also compared. Depending on the urea concentration, the structural phases were classified as PEO+${\beta}$-phase composite, ${\beta}$-phase+${\alpha}$-phase composites, or ${\alpha}$-phase composite+urea. At urea concentrations below ~0.064 M, the ${\beta}$-phase was dominant in the complex film. Moreover, the conductance increased rapidly with an increase in the urea concentration. For urea concentrations ranging from ~0.064 to ~0.25 M, the ${\beta}$-phase was gradually substituted by the ${\alpha}$-phase. As the film was composed entirely of the ${\alpha}$-phase at urea concentrations greater than ~0.25 M, its conductance was decreased. In this study, the electrical characteristics observed for the different phases are analyzed and discussed.

Insights into the Diverse Roles of miR-205 in Human Cancers

  • Orang, Ayla Valinezhad;Safaralizadeh, Reza;Feizi, Mohammad Ali Hosseinpour
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.2
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    • pp.577-583
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    • 2014
  • The recent discovery of tiny microRNAs (miRNAs) has brought about awareness of a new class of regulators of diverse pathways in many physiological and pathological processes, such as tumorigenesis. They modulate gene expression by targeting plethora of mRNAs, mostly reducing the protein yield of a targeted mRNA. With accumulation of information on characteristics of miR-205, complex and in some cases converse roles of miR-205 in tumor initiation, progression and metastasis are emerging. miR-205 acts either as an oncogene via facilitating tumor initiation and proliferation, or in some cases as a tumor suppressor through inhibiting proliferation and invasion. The aim of this review is to discuss miR-205 roles in different types of cancers. Given the critical effects of deregulated miR-205 on processes involved in tumorigenesis, they hold potential as novel therapeutic targets and biomarkers.

Development of Complex Regional Pain Syndrome after a Snake Bite: A Case Report

  • Seo, Yong Han;Park, Mi Ran;Yoo, Sie Hyeon
    • The Korean Journal of Pain
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    • v.27 no.1
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    • pp.68-71
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    • 2014
  • The occurrence of CRPS after a snake bite was very rare, only two cases were reported worldwide. Here we report a case that the 44-year-old female patient bitten by snakes CRPS type 1 was treated consecutive intravenous regional block, lumbar sympathectomy and antiepileptic drug therapy, also discuss the possible pathophysiology.

Flexible docking of novel antitumor agents into human topoisomerase I-DNA complex with FlexiDock

  • Woo , Su-Na;Kim, Choon-Mi
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.314.2-314.2
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    • 2002
  • DNA topoisomerases catalyze changes in DNA topology through cycles of transient DNA strand breakage and religation. During this process. the active site tyrosine in human DNA topoisomerase Ⅰ(Top Ⅰ) becomes covalently linked to the 3'-ends of a single-stranded nick in the DNA duplex, Stabilization of the Top Ⅰ-DNA cleavable complex is the common initial event leading to the cytotoxicity of top 1 inhibitors. (omitted)

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Thermosome-like Protein from Hyperthermophilic Archaeon Thermococcus Profundus; Purification and Structural Analysis (초고온 Archaeon인 Thermococcus profundus로부터 Thermosome유사 단백질의 분리 및 구조 분석)

  • Kim, Suk-Kyoung;Lee, Mi-Hong;Park, Seong-Cheol;Cheong, Gang-Won
    • Applied Microscopy
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    • v.30 no.4
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    • pp.413-421
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    • 2000
  • We have isolated a large cylindrical protein complex from hyperthermophile archaeon Thermococcus profundus. Structural analysis by image processing of electron micrographs suggests that the complex is composed of two stacked rings of eight subunits each; the ring enclose a central channel. The purified protein was shown to be a homomultimer of 60 kDa subunit (P60 complex). It exhibits an extremely thermostable ATPase activity with a temperature optimum of $80^{\circ}C$. This protein complex may play an important role in the adaptation of thermophile archaeon to life at high temperature.

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Structural Analysis of the Cu-binding Site in the [Cu·dCMP·dCMP-H]1- Complex

  • Jung, Sang-Mi;Kim, Ho-Tae
    • Mass Spectrometry Letters
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    • v.4 no.4
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    • pp.67-70
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    • 2013
  • The Cu-binding site in the $[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ complex was investigated. The tandem mass (MS/MS) spectra of the [$[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ parent ion showed $[dCMP{\cdot}Cu{\cdot}H_2PO_4+CONH]^{1-}$ fragment ions. Therefore, we propose that the Cu cation is simultaneously coordinated to the phosphate site and cytosine moiety in the stable geometry of the $[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ complex. Three geometries for the complex were considered in an attempt to optimize the structure of the $[Cu{\cdot}dCMP{\cdot}dCMP-H]^{1-}$ complex. The ab initio calculations were performed at the $B3LYP/6-311G^{**}$ level.

Research on Current Combination of Public facilities in Metropolitan - Seoul, Daejon, & Pusan - (대도시 공동체 공공시설의 복합화 현황조사 - 서울, 대전, 부산을 중심으로-)

  • Kim, Sun-Mi;Suh, Kuee-Sook
    • Proceeding of Spring/Autumn Annual Conference of KHA
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    • 2008.04a
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    • pp.334-338
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    • 2008
  • The purpose of this study is to examine present situation of complex community center and to develop complex community center which is considered character of the region. The method of this study was research on internet and interview with public institution by phone about the kind, scale, present situation, complex form of public institution which is situated in Seoul, Busan and Daejeon. The results of the study are as follow : 1) There is the most administration institutions in Seoul and Busan and Daejeon has the most welfare facilities among the public institutions. 2) The scale of public institution is the most buildings of $3{\sim}4$ floors. 3) The institution consisted of one facility is more than 50% in complex form. 4) The complex forms are 21 types of similar facilities and 36 types of different facilities. Therefore, public institutions were attached in Seoul, various types of facilities were not placed in Busan and Daejeon or the number of public institution has been increased continuously, but complex institution considered by social request is difficult to find.

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Prion Protein Does Not Interfere with SNARE Complex Formation and Membrane Fusion

  • Yang, Yoo-Soo;Shin, Jae-Il;Shin, Jae-Yoon;Oh, Jung-Mi;Lee, Sang-Ho;Yang, Joo-Sung;Kweon, Dae-Hyuk
    • Food Science and Biotechnology
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    • v.18 no.3
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    • pp.782-787
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    • 2009
  • In prion disease, spongiform neurodegeneration is preceded by earlier synaptic dysfunction. There is evidence that soluble N-ethylmaleimide sensitive factor attachment receptor (SNARE) complex formation is reduced in scrapie-infected in vivo models, which might explain this synaptic dysfunction because SNARE complex plays a crucial role in neuroexocytosis. In the present study, however, it is shown that prion protein (PrP) does not interfere with SNARE complex formation of 3 SNARE proteins: syntaxin 1a, SNAP-25, and synaptobrevin. Sodium dodecyl sulfate-resistant complex formation, SNAREdriven membrane fusion, and neuroexocytosis of PC12 cells were not altered by PrP. Thus, PrP does not alter synaptic function by directly interfering with SNARE complex formation.