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Promotion of excisional wound repair by a menstrual blood-derived stem cell-seeded decellularized human amniotic membrane

  • Farzamfar, Saeed;Salehi, Majid;Ehterami, Arian;Naseri-Nosar, Mahdi;Vaez, Ahmad;Zarnani, Amir Hassan;Sahrapeyma, Hamed;Shokri, Mohammad-Reza;Aleahmad, Mehdi
    • Biomedical Engineering Letters
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    • v.8 no.4
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    • pp.393-398
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    • 2018
  • This is the first study demonstrating the efficacy of menstrual blood-derived stem cell (MenSC) transplantation via decellularized human amniotic membrane (DAM), for the promotion of skin excisional wound repair. The DAM was seeded with MenSCs at the density of $3{\times}10^4cells/cm^2$ and implanted onto a rat's $1.50{\times}1.50cm^2$ full-thickness excisional wound defect. The results of wound closure and histopathological examinations demonstrated that the MenSC-seeded DAM could significantly improve the wound healing compared with DAM-treatment. All in all, our data indicated that the MenSCs can be a potential source for cell-based therapies to regenerate skin injuries.

Study on torso body types of adult males over 178cm tall (178cm 이상의 키 큰 성인남성에 대한 체간부 체형 유형화 연구)

  • Kim, Min-jung
    • The Research Journal of the Costume Culture
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    • v.30 no.5
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    • pp.675-688
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    • 2022
  • The purpose of this study is to analyze the body type characteristics of tall adult men aged 20 to 69 years to present base material on body dimensions for men's clothing companies. The research method comprised statistical analysis of 3D measurements after selecting items from the 8th Korean human body size survey related to the torso body types of 495 adult men who were at least 178cm tall. As a result, six factors were extracted, and the total explanatory variable of the entire factor was shown to be 80.499%. As a result of cluster analysis using this as an independent variable, three types were derived: Type 1, "a normal body type with an oval cross-sectional shape" (37.6%), with a larger vertical size and an oval chest cross-sectional shape compared to other types; Type 2: a "cylindrical thick body shape" (31.1%), which is the first stage of BMI obesity, with narrow shoulders and a cylindrical shape with a round cross-section; Type 3, "a body shape with broad shoulders and developed chest parts" (31.3%), with a horizontal size similar to Type 2 above the waist, but similar to Type 1 below. The results of this study are expected to be used as a basis for a clothing dimension system and clothing development for tall men reflecting the characteristics of the torso.

Analysis of the 50s and 60s Middle-Aged Men's Upper Body Type - Using on the 8th Size Korea's Direct Measurement Data - (50-60대 중장년 남성의 상반신 체형 분석 - 사이즈 코리아 제 8차 직접측정자료를 중심으로 -)

  • Jin Hee Lee
    • Journal of the Korea Fashion and Costume Design Association
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    • v.25 no.4
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    • pp.1-11
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    • 2023
  • The purpose of this study was to characterize the upper body shape of men in their 50s and 60s by analyzing direct measurement data. Sixty one direct measurement items were analyzed. Subjects (n = 752) were classified based on 5 factors into 4 body types. In order to acquire accurate upper body shape information by analyzing body type using the 8th Size Korea direct measurement data, body shapes were classified through factor and cluster analysis. As a result of the comparative analysis of the upper body measurements from the 5th to the 8th Size Korea measurement, it was found that waist circumference item tended to increase significantly from the 5th Size Korea measurements. The upper body type of middle aged males were classified using five factors: the trunk obesity factor, the trunk vertical factor, the width of the back shoulder, the vertical factor behind the back, and the length factor of the upper body. Middle-aged men were classified into four body types through cluster analysis. Type 1 is relatively short with big arms, Type 2 has wide shoulders and thin arms, and in Type 3, the upper body is relatively long. Type 4 is the most obese upper body.

Studies on the Modeling of the Three-dimensional Standard Face and Deriving of Facial Characteristics Depending on the Taeeumin and Soyangin (소양인, 태음인의 표준 3차원 얼굴 모델링 개발 및 그 특성에 관한 연구)

  • Lee, Seon-Young;Hwang, Min-Woo
    • Journal of Sasang Constitutional Medicine
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    • v.26 no.4
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    • pp.350-364
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    • 2014
  • Objectives This study was aimed to find the significant features of face form according to the Taeeumin and Soyangin by analyzing the three-dimensional face information data. Also, making standard face of the Taeeumin and Soyangin was an object of this study. Methods We collected three-dimensional face data of patients aged between 20~45 years old diagnosed by a specialist of Sasang constitutional medicine. The data were collected using a 3D scanner, Morpheus 3D(Morpheus Corporation, KOREA). Extracting a face feature point total of 64, was set to 332 pieces(height, angle, ratio, etc.) of each variable between feature points. ANOVA test were used to compare the characteristics of subjects according to the Taeeumin and Soyangin. Results When not to consider gender, the Taeeumin and Soyangin were different from the 18 items(3 items in the ear, 9 items in the eye, 1 item in the nose, 1 item in the mouth, 4 items in the jaw). When to consider gender, the Taeeumin and Soyangin men were different from the 6 items(1 item in the ear, 2 items in the nose, 3 items in the face). And the Taeeumin and Soyangin women were different from 17 items(1 item in the ear, 10 items in the eye, 2 items in the nose, 1 item in the mouth, 3 items in the face). Conclusions These results show Taeeumin's face(both men and women) width of the right and left is larger than the length of the top and bottom. Compared to men of Soyangin, men of Taeeumin has greater wings of the nose. Compared to women of Soyangin, women of Taeeumin has longer length of the eye. Soyangin's face(both men and women) length of the top and bottom is larger than the width of the right and left. Compared to men of Taeeumin, men of Soyangin has smaller wings of the nose. Compared to women of Taeeumin, women of Soyangin has more stereoscopic facial features at the top and bottom of the lateral face. Also, by accumulating three-dimensional face data, this study modeled the standard facial features by Taeeumin and Soyangin. These results may be helpful in the development of Sasang constitutional diagnostics utilizing the characteristics of the facial form at later.

Relationship of Socioeconomic Factors with Medical Utilization for Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia in a South Korean Community (지역사회 성인남성에서의 하부요로증상 및 전립선비대증 의료이용과 사회경제적 요인의 관련성)

  • Kim, Han-Hae;Kong, Kyoung-Ae;Lee, Hun-Jae;Yoon, Ha-Na;Lee, Bo-Eun;Moon, Ok-Ryun;Park, Hye-Sook
    • Journal of Preventive Medicine and Public Health
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    • v.39 no.2
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    • pp.141-148
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    • 2006
  • Objectives : We wanted to evaluate the medical underutilization for benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) among Korean elderly men and we wanted to determine their associated factors. Methods : This study was conducted on 239 men with LUTS and 116 men with BPH who were compatible with the diagnostic criteria from a total of 641 participants. These participants were over 50 years old and they were randomly chosen in a community-based study for estimating the prevalence of BPH. Using a self-reported questionnaire, we surveyed the sociodemographics, health status, quality of life, lower urinary tract symptoms, medical utilization and reasons for not seeking treatment. Results : Only 27.6% of the men with LUTS and 31.0% of the men with BPH reported having visited a doctor for urinary symptoms. The reasons for not visiting a doctor were, in order of responses from the group with LUTS: 'considered the symptoms as a part of the normal ageing process', 'not enough time to visit a doctor', 'financial difficulty' and 'the symptoms were not severe or bothersome'. Regarding BPH, the responses were the same as those of the group with LUTS however, 'financial difficulty' placed second. Among the men with experience of visiting a doctor for urinary symptoms, 33.3% of those with LUTS and 28.1% of those with BPH were not treated. The most common reason in both groups was 'the symptoms were not severe to be treated'. On a multiple logistic regression analysis, the larger size household (odds ratio (OR) 3.03, 95% confidence interval (CI)=1.40-6.54) and an unsatisfactory quality of life related with urinary symptoms (OR 2.98, 95% CI=1.23-7.21) were associated with medical utilization in the group of LUTS. For BPH, the current employment status was related with the medical utilization (OR 2.80, 95% CI=1.10-7.11), in addition to the larger size household (OR 3.24, 95% CI=1.14-9.21). Conclusions : Many men with urinary symptoms do not visit a doctor. This medical underutilization for people with LUTS and BPH may be associated with economic status in Korea.

Observation on Neck Form Changes Related to Aging in Men(Part I) -Using the Sliding Gause Measurement Method- (성인남자 목부위의 연령별 형태변화에 관한 연구(제1보) -슬라이딩 게이지법에 의한 분석-)

  • 이영숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.18 no.2
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    • pp.252-262
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    • 1994
  • As a means to get a better understanding of the kind of form changes to which is subject the neck of the men, in its aging process, several measurement recordings on a vertical and horizontal sections were carried. Subjects were young, middle aged and elder men (15 in their twenties, 11 in their forties and again 11 in their sixties) 1) The analysis of the meansurement results led us to distinguish 3 types of subjects according to the position of the their Adam's apple with regard to the horizontal plane containing their 7th cervical vertebrae point : clearly above (Type I), next to(Type II), clearly below(Type III). We found that young men correspond to the Type I and II, middle aged men to the Type ll and 111 and elder men only to the Type III. 2) The comparison of the horizontal sectional surface contained in the planes corresponding to the 4 points, shows a larger sectional surface for elder men in the Adam's apple plane, accompanied by a change of position of the Adam's apple forwards. As for the front neck point plane, the body sectiolial surface is larger in depth in elder men, without much change in breadth. And for the acromion point plane, we observed also an increase in depth, but with a decrease in breadth corresponding partially to the atrophy of the thoraric cage in eldermen.

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Prediction of Colorectal Cancer Risk Using a Genetic Risk Score: The Korean Cancer Prevention Study-II (KCPS-II)

  • Jo, Jae-Seong;Nam, Chung-Mo;Sull, Jae-Woong;Yun, Ji-Eun;Kim, Sang-Yeun;Lee, Sun-Ju;Kim, Yoon-Nam;Park, Eun-Jung;Kimm, Hee-Jin;Jee, Sun-Ha
    • Genomics & Informatics
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    • v.10 no.3
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    • pp.175-183
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    • 2012
  • Colorectal cancer (CRC) is among the leading causes of cancer deaths and can be caused by environmental factors as well as genetic factors. Therefore, we developed a prediction model of CRC using genetic risk scores (GRS) and evaluated the effects of conventional risk factors, including family history of CRC, in combination with GRS on the risk of CRC in Koreans. This study included 187 cases (men, 133; women, 54) and 976 controls (men, 554; women, 422). GRS were calculated with most significantly associated single-nucleotide polymorphism with CRC through a genomewide association study. The area under the curve (AUC) increased by 0.5% to 5.2% when either counted or weighted GRS was added to a prediction model consisting of age alone (AUC 0.687 for men, 0.598 for women) or age and family history of CRC (AUC 0.692 for men, 0.603 for women) for both men and women. Furthermore, the risk of CRC significantly increased for individuals with a family history of CRC in the highest quartile of GRS when compared to subjects without a family history of CRC in the lowest quartile of GRS (counted GRS odds ratio [OR], 47.9; 95% confidence interval [CI], 4.9 to 471.8 for men; OR, 22.3; 95% CI, 1.4 to 344.2 for women) (weighted GRS OR, 35.9; 95% CI, 5.9 to 218.2 for men; OR, 18.1, 95% CI, 3.7 to 88.1 for women). Our findings suggest that in Koreans, especially in Korean men, GRS improve the prediction of CRC when considered in conjunction with age and family history of CRC.

A Clinical Study on the Decreased Visual Acuity (視力低下에 對한 臨床的 考察)

  • Choi, Eun-Sung;Ryu, Hye-Jeong;Chae, Byung-Yoon
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.9 no.1
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    • pp.146-158
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    • 1996
  • We observed 79 patients, who visited the Department of Oph. & Otorhinolaryngology in Oriental medicine of Kyung Hee University Medical Center from July 1995 to June. 1996, with the complaint of decreased visual acuity. The results were as follows. 1. In the incidence of decreased visual acuity, men's was $46.84\%$(37 cases) and women's was $53.16\%$(42 cases), which showed that more women were suffering decreased visual acuity than men. In the incidence of myopic ametropia and astigmatic ametropia among the total patients, men's was $44.62\%$(29 cases) and $37.50\%$(9 cases) each, and women's was $55.38\%$(36 cases) and $62.50\%$( 15 cases) each, which also showed that more women were suffering myopia and astigmatism than men. 2. The average age of patients was 11.08 years at the first visit. The most were the patients from 6 to 15 years old, with 63 cases($79.74\%$). 3. The age of onset in the decreased visual acuity was mainly 6∼10 years with 45 cases($56.96\%$). In the case of myopic ametropia and astigmatic ametropia, the age of onset was also mainly 6∼10 years with 65 cases($60.00\%$), and with 12 cases($50.00\%$) each. 4. In ABO blood type, the frequency was, A type, O type, B type and AB type in order. In men, O type was the most, while in women, A type. 5. In the liking for cool or warm food or tepidity, the liking for cool food was the most in both men and women. 6. The type of decreased visual acuity was mainly myopic ametropia with 65 cases($82.28\%$). Astigmatic ametropia was $30.38\%$ with 24 cases, hyperopic ametropia $2.53\%$ with 4 cases, and the decreased visual acuity accompanied by amblyopia $7.59\%$ with 4 cases. 7. At the first visit, the average visual acuity of O.D. was 0.29 and that of O.S.. 0.24, which showed that O.S.. is worse than O.D.. The visual acuity below 0.2 was the most, $63.29\%\;in\;O.D..\;72.15\%$ in O.S.. 8. In the treatment period, 4∼7 weeks occupied $35.44\%$ with 28 cases, 8∼11 weeks $30.38\%$ with 24 cases, so the treatment period was mainly these two periods with 52 cases($65.82\%$). 9. The average frequency of acupuncture treatment per week was mainly 2.1∼3.0 times with 45 cases($56.96\%$). In this case, men was 24 cases($53.33\%$) and women 21 cases($46.67\%$), so men was more than women. 10. The frequency of herbal prescription was mainly Gamijungjitang and Gamijingjibogansan with 76 cases($85.39\%$).

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Effect of Satisfaction with the Marriage Support Policy on Marriage Intention among Unmarried Employed Men and Women - Focusing on Unmarried Employed Men and Women of Marriageable Age Residing in the Seoul City and Metropolitan Area - (취업미혼남녀의 결혼지원정책 만족도가 결혼의향에 미치는 영향 - 서울시 및 수도권 결혼적령기 취업 미혼남녀를 중심으로 -)

  • Park, Ju-Hee
    • Journal of Family Resource Management and Policy Review
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    • v.21 no.4
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    • pp.1-15
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    • 2017
  • The purpose of this study was to identify the effect of satisfaction with the marriage support policy on marriage intention among unmarried employed men and women. The study subjects included 300 unmarried working men and women aged over 30 years residing in the Seoul metropolitan area. First, according to the analysis of the subjects' overall tendency towards satisfaction with the marriage support policy and towards marriage intention, the marriage support policy gained the highest level of support in relation to housing for newlywed couples, which scored 3.29 (sd=.93), followed by improvements in corporate and family culture for the purposes of work-family compatibility at 3.24 (sd=.95), wedding loans at 3.18 (sd=1.01), and the paid leave system for marriage preparation at 3.12 (sd=.88). These variables scored slightly higher than the median 3 points. Conversely, satisfaction with the availability of marriage-related information and the provision of opportunities for dating scored 2.65 (sd=.88) and 2.78 (sd=.80), respectively, both of which were slightly lower than the median of 3. The overall mean score for satisfaction with the marriage support policy was 3.03 (sd=.95), which was slightly higher than the median of 3. In regards to marriage intention, the score was 3.32 (sd=1.15) points out of a perfect score of 5, which was slightly higher than the median. This indicated a slightly higher level in terms of the subjects' intention to marry. Second, a hierarchical regression analysis was performed to identify the effect of satisfaction with the marriage support policy on marriage intention among unmarried employed adults. Sociodemographic variables were entered as control variables in the regression at the first stage, and variables relating to satisfaction in a family-friendly social environment were entered at the second stage. When gender, age, educational level, monthly income, period of employment, working hours, and type of employment were inserted in the first stage of regression as control variables, gender, monthly income, period of employment, and type of employment were found to have a significant effect on marriage intention. Marriage intention was found to be greater in unmarried men with higher monthly incomes and longer periods spent working, and in unmarried working men and women engaged in tenured employment work. When variables relating to satisfaction with the marriage support policy were inserted in the second stage of regression, gender, monthly income, type of employment, and satisfaction with direct marriage support had significant effects on marriage intention. It was found that marriage intention was greater in unmarried men whose monthly income was higher, whose employment type was tenured work, and who showed greater satisfaction with direct marriage support.

Health and dietary characteristics of the men and women in their middle age according to health-related quality of life: using the Korea National Health and Nutrition Examination Survey data in 2019 and 2021 (중년 남성과 여성의 건강 관련 삶의 질에 따른 건강 및 식생활 특성: 2019년, 2021년 국민건강영양조사 자료를 이용하여)

  • Sarim Kim;Yoon Jung Yang
    • Journal of Nutrition and Health
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    • v.57 no.3
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    • pp.307-319
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    • 2024
  • Purpose: This study compared the differences in health and dietary characteristics between middle-aged men and women according to their health-related quality of life. Methods: This study used the data from the 2019 and 2021 Korea National Health and Nutrition Examination Survey (KNHANES). The participants were men (n = 1,571) and women (n = 2,179) aged 40-59. A health-related Quality of Life Instrument with eight items (HINT-8) was used to measure the health-related quality of life. The participants were divided into four groups based on their HINT-8 total scores (high, mid-high, mid-low, and low). The general and health characteristics, mental health, and dietary behaviors were compared according to the quality of life. Results: Men with a lower quality of life had lower incomes, were more likely to be single, smoked and drank more, and perceived themselves as slim or obese. Women with a lower quality of life had a higher proportion of older age, obesity, lower education and income, hypercholesterolemia, and hypertriglyceridemia. Both men and women with a lower quality of life had higher proportions of subjectively perceiving poor health, weight gain over the past year, and considering themselves as obese. Both men and women with a lower quality of life had lower consumption frequencies of vegetables/mushrooms/seaweed and fruits. Conclusion: Both men and women with lower health-related quality of life had lower incomes, higher rates of perceiving their health as poor, and consumed vegetables/ mushrooms/seaweed and fruits less frequently, but they showed different characteristics in other aspects. Therefore, policy development tailored to men and women is necessary.