• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9335-9339
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• 2014

Background: To determine the frequency of primary circulating prostate cells (CPC) detection according to age and serum PSA levels in a cohort of men undergoing screening for prostate cancer and to determine the diagnostic yield in those men complying with the criteria for prostate biopsy. Materials and Methods: A prospective study was carried out to analyze all men evaluated in a hospital prostate cancer screening program. Primary CPCs were obtained by differential gel centrifugation and detected using standard immunocytochemistry using anti-PSA, positive samples undergoing a second process with anti-P504S. A malignant primary CPC was defined as PSA+ P504S+, and a test positive if 1 cell/4ml was detected. The frequency of primary CPC detection was compared with age and serum PSA levels. Men with a PSA >4.0ng/ml and/or abnormal rectal examination underwent 12 core prostate biopsy, and the results were registered as cancer/no-cancer and compared with the presence/absence of primary CPCs to calculate the diagnostic yield. Results: A total of 1,117 men participated; there was an association of primary CPC detection with increasing age and increasing serum PSA. Some 559 men underwent initial prostate biopsy of whom 207/559 (37.0%) were positive for primary CPCs and 183/559 (32.0%) had prostate cancer detected. The diagnostic yield of primary CPCs had a sensitivity of 88.5%, a specificity of 88.0%, and positive and negative predictive values of 78.3% and 94.9%, respectively. Conclusions: The use of primary CPCs for testing is recommended, since its high negative predictive value could be used to avoid prostate biopsy in men with an elevated PSA and/or abnormal DRE. Men positive for primary CPCs should undergo prostate biopsy. It is a test that could be implemented in the routine immunocytochemical laboratory.

• Journal of Families and Better Life
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• v.23 no.6 s.78
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• pp.155-165
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• 2005

The pupose of this study is to investigate the effect of irrational relationship beliefs on marital duality of married men and women and to find out what sub-scales of irrational relationship beliefs have effect on marital quality. The data were collected from 301 married men and 302 married women living with their unmarried children in the metropolitan area around Seoul. All the respondents were asked to answer the self-reporting questionnaires. The analysis includes frequencies, means, 1-test, one-way ANOVA, Duncan test, and hierarchical multiple regression models. the major findings are as follows. 1) The level of irrational relationship beliefs is below the average, and the married women show slightly higher level of irrational relationship beliefs than the men. On the other hand, the level of marital quality of the married men and women is slightly above the average with no difference between the men and the women. 2) In the case of the married men, the sub-scales of irrational relationship beliefs that have significantly negative effect on the marital quality are 'partners cannot change', 'disagreement is destructive,' and 'sexes are different' 3) In the case of the married women, the sub-scales of irrational relationship beliefs that have significantly negative effect on the marital quality are 'partners cannot change' and 'disagreement is destructive' According to the result of this study, irrational relationship beliefs have negative effect on marital quality. However, the effect of each sub-scales shows slight differences in gender. The finding of this study suggests that a promoting marital promoting marital qualify by reducing the irrational relationship beliefs should take the gender differences into consideration.

• Nutrition Research and Practice
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• v.12 no.1
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• pp.47-51
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• 2018

BACKGROUND/OBJECTTIVES: The purposes of the study were to investigate folate intakes and plasma folate concentrations as well as estimate folate status in Korean healthy adults. SUBJECTS/METHODS: A total of 254 healthy 19- to 64-year-old adults (68 men and 186 women) living in Seoul metropolitan area, Gumi, and Kwangju, Korea participated. Three consecutive 24-hour dietary recalls, information on folate supplementation, and fasting blood samples were collected from the subjects. RESULTS: The mean dietary folate intakes were 587.4 and $499.2{\mu}g$ dietary folate equivalent (DFE)/day for men and women, respectively. The median dietary intakes of men and women were 566.6 and $474.6{\mu}g\;DFE/day$, respectively. Forty subjects (16.7% of total) less total folate than the estimated average requirement (EAR). Folate intakes of 23.3% of men and 34.8% of women aged 19-29 years did not meet the EAR for folate. Major food sources consumed for dietary folate were baechukimchi (Chinese cabbage kimchi), rice, spinach, eggs, and laver, which provided 44% of dietary folate intake for the subjects. Plasma folate concentrations were 23.4 nmol/L for men and 28.3 nmol/L for women, and this level was significantly lower in men than in women. Approximately 13% of men and 3% of women were folate-deficient, and the percentages of subjects showing folate concentrations lower than 10 nmol/L were 27.9% of men and 6.4% of women. CONCLUSIONS: Folate intakes of Korean adults in this study were generally adequate. However, one-third of young adults had inadequate folate intakes.

• Journal of the Korean Home Economics Association
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• v.43 no.3 s.205
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• pp.199-219
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• 2005

The purpose of this study was to examine how life-changes after divorce, individual resources, and interpersonal resources affect post-divorce adjustment. Especially it focuses on gender differences. Data were collected from 114 divorced men and 112 divorced women in their 20s and 30s with the inclusion criteria of 1) having hen divorced for at least 6 months but less than 5 years, and 2) not having remarried after divorce. AH divorced men and women were interviewed with self-report questionnaires. The analysis included frequencies, means, t-test, crosstabs, and hierarchical multiple regression models. The major findings were as follows. 1) Divorced women were better adjusted than divorced men. 2) Fnancial satisfaction and health problems were important factors for both divorced men and women. 3) There were gender differences in the variables that affected post-divorce adjustment. Social support and significant others' attitude toward divorce influenced post-divorce adjustment for divorced men. For divorced women, negative change in financial circumstances, their own attitude toward divorce and divorce initiation found significant. This study showed that there were gender differences in the factors affecting Post)divorce adjustment. The findings of this study suggest that a program for supporting divorced men and women should consider gender differences.

• Journal of The Korea Institute of Healthcare Architecture
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• v.27 no.1
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• pp.17-34
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• 2021

Purpose: The purpose of this study was to find out the difference in the priority level of recognition for universal design application in public spaces by gender. Method: ANOVA(analysis of variance) and post-hoc test were conducted to determine the priority level of recognition and pattern for the disabled, non-disabled, and experts classified into males and females. Results: There was no gender difference in the comparison by sector for all males and females. However, in comparing of domains and facilities, women showed a higher level of recognition than men in the building sector and cross domain. When comparing space consumers and producers by dividing them into male and female groups, women showed a higher level of recognition than men in producers, but there was no gender difference between consumers. In comparison by sector, domain and facility, women producers also showed a higher level of recognition in the road sector, park and recreation sector, sidewalk domain, four-spaces in the park and recreation sector, and six-spaces in the building sector than men producers. Also, in the building sector, women producers and consumers showed a higher recognition level than men. Comparing the disabled, non-disabled people and experts by dividing them into male and female groups, in the case of non-disabled people and experts, women showed a higher level of recognition than men, while men showed a higher level of recognition than women in the disabled. In addition, there were differences in recognition patterns in many spaces and facilities by gender. Implications: This study is meaningful in comparing the differences in the priority level of recognition and patterns between men and women to apply universal design for people of all ages and both sexes.

• Molecules and Cells
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• v.21 no.2
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• pp.251-260
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• 2006

During mitosis, genomic integrity is maintained by the proper coordination of anaphase entry and mitotic exit via mitotic checkpoints. In budding yeast, mitotic exit is controlled by a regulatory cascade called the mitotic exit network (MEN). The MEN is regulated by a small GTPase, Tem1p, which in turn is controlled by a two-component GAP, Bfa1p-Bub2p. Recent results suggested that phosphorylation of Bfa1p by the polorelated kinase Cdc5p is also required for triggering mitotic exit, since it decreases the GAP activity of Bfa1p-Bub2p. However, the dispensability of GEF Lte1p for mitotic exit has raised questions about regulation of the MEN by the GTPase activity of Tem1p. We isolated a Bfa1p mutant, $Bfa1p^{E438K}$, whose overexpression only partially induced anaphase arrest. The molecular and biochemical functions of $Bfa1p^{E438K}$ are similar to those of wild type Bfa1p, except for decreased GAP activity. Interestingly, in $BFA1^{E438K}$ cells, the MEN could be regulated with nearly wild type kinetics at physiological temperature, as well as in response to various checkpoint-activating signals, but the cells were more sensitive to spindle damage than wild type. These results suggest that the GAP activity of Bfa1p-Bub2p is responsible for the mitotic arrest caused by spindle damage and Bfa1p overproduction. In addition, the viability of cdc5-2 ${\Delta}bfa1 $ cells was not reduced by $BFA1^{E438K}$, suggesting that Cdc5p also regulates Bfa1p to activate mitotic exit by other mechanism(s), besides phosphorylation.

• Journal of the Ergonomics Society of Korea
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• v.31 no.1
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• pp.247-254
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• 2012

Objective: The objective of the study is to analyze adult men's somatotype characteristics, age range from 20s to 50s comparing the direct anthropometric measurement values and to provide the basis information for developing clothing patterns. Background: The comparative study among the age groups is very fundamental to understand the body characteristics of each subjects group. Therefore, comparison of body measurements in age groups was applied in this study. Method: The anthropometric data from the $5^{th}$ Anthropometry of Size Korea(2004) and $6^{th}$ Anthropometry of Size Korea(2010) were applied for the data analysis. Results: As a result, the chest depth/chest width index(the value of chest depth divided by chest width) was increased and the waist depth/waist width index was decreased in all age groups. In addition, the hip depth/hip width index was decreased in age of 20's and 50's. This means that the chest width and hip width were decreased and the waist width were increased. From the data of the 5th Size Korea, the obese men(BMI: 25~30) in the 50s showed the highest percentage of 47.1%, and 44.8% of obese men(BMI: 25~30) in the 40s recorded the highest rate base on the data of the 6th Size Korea. Conclusion: It is concluded that the some differences were showed between the 5th anthropometric data and the 6th data. In particular, obesity tendencies of men in their 20's and 30's were observed significantly compared to other age groups. Application: These findings from the study can be utilized men's wear design and construction that reflect body characteristics.

• Korean Journal of Applied Biomechanics
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• v.13 no.3
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• pp.133-149
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• 2003

The purposes of present study were to determine the major check-points of golf swing from the review of previous studies, and to suggest additional information on the teaching theory of golf. The golf swing motion of 6 male and female elite university golf players were filmed with 16mm Locam II high speed cameras at the speed of 200f/s, and variables such as time, displacement, angle, velocity were calculated and analyzed by 3D Cinematography using DLT method. The results were: 1. Differences were shown in the ratio of weight distribution on the feet, cocking angle, take-back velocity, club-head velocity at impact depending upon the physical characteristics and club used for swing. 2. Time for the down-swing and impact were $0.27{\sim}0.29s$ in men and $0.29{\sim}0.32s$ in women, which was 1/3 of the time for the back-swing. Women showed longer total swing time than men because of longer time in back-swing, follow-through and finish. 3. Men showed larger range of motion in shoulder and knee joints than women, on the other hand women showed larger range of motion in hip joint than men. 4. Cocking motion and right elbow flexion were occurred at the top of back-swing and cocking release was occurred at the moment of impact. Maximum rotations of shoulder and hip joints were found between the top of back-swing and down-swing phase. 5. Women showed lower back-swing velocity than men, and men showed higher club velocity(men: $38.2{\sim}38.6m/s$, women: $35.1{\sim}36.4m/s$) than women.

• Journal of Nutrition and Health
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• v.39 no.7
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• pp.684-691
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• 2006

Abdominal obesity (AO) is a strong risk factor for type 2 diabetes and cardiovascular disease, which has shown a remarkable increase in Korea. This study aimed to identify prevalence of AO and related risk factors in Korean adults. A total of 5,132 men and women aged 20-85 years old from the 2001 Korean National Health and Nutrition Examination Survey were included in the analyses. AO was defined as waist circumference >=90 cm in men and >=85 cm in women as proposed by Korean Society of Obesity. Multiple logistic regression was carried out to identify risk factors for AO. Three models were specified: (i) demographic and socioeconomic factors (model 1: age, education, poverty income ratio, employment), (ii) lifestyle factors and covariates (model 2: physical activity, cigarette smoking, alcohol consumption, dietary quality, type 2 diabetes, co-morbidity) and (iii) demographic, socioeconomic and lifestyle factors (model 3). The prevalence of AO was 24.1 % in men, 23.5% in women. High poverty income ratio in men and low education attainment in women were risk factors for AO in model. 1. There was a significant association of AO with alcohol consumption, physical inactivity and dietary quality in men, alcohol consumption and cigarette smoking in women. These factors except alcohol consumption in men became insignificant in model 3. This findings underscore the importance of developing AO prevention programs in Korea that target the at risk groups identified in this study. A program focusing on low income men or less educated women would be more efficient.

• Journal of the Korean Society of Clothing and Textiles
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• v.33 no.1
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• pp.1-10
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• 2009

The purpose of this study was to investigate the effects of the types and the colors of men's casual wear, hairstyles, and the methods of stimulus manufacture on men's image perception. The subjects were 360 women from the metropolitan area of Seoul. The clothing types used for the study were a sweater and a jumper(casual jacket) with jean pants. The clothing colors were beige, indigo, and red. Two hairstyles, the short and the medium length hairs, were compared. Two types of stimuli, the photograph and the computer simulation picture, were used. The results of the factor analysis disclosed five dimensions on men's image: neatness, individuality, ability, activity, and sociability. In general, the photograph stimuli were evaluated more positively in activity, individuality, and sociability than the picture stimuli. The sweaters were perceived higher in ability, activity, and sociability than the jumpers. The Indigo color was evaluated as neat. The medium length hairstyles were perceived as neat and the short hairstyles were perceived as sociable. The jumpers were evaluated lower in individuality in the picture stimuli than in the photograph stimuli. The beige and indigo colors were evaluated to be neater in the picture stimuli than in the photograph. When using the picture stimuli, the men's image wearing the sweaters with the medium length hairstyles were evaluated lower in individuality. When using the photograph stimuli, the men's image wearing the sweater with the short hairstyles were evaluated higher in activity. Men's image wearing the indigo jumper and the beige sweater with medium length hairs were evaluated as high in neatness.