• Title/Summary/Keyword: MD-2

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제15회 산란계 경제능력 검정 성적

  • 국립종축장;대한양계협회
    • KOREAN POULTRY JOURNAL
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    • v.13 s.146
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    • pp.108-116
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    • 1981
  • 제15회 산란계 경제능력검정에는 총 13개 계군이 출품되었으며 능력검정 결과를 요약하면 다음과 같다. 1. 육추율, 육성율, 성계생존율 이번회 검정계의 육추율은 13개 계군 평균 97.72$\%$로서 14회 99.7$\%$와 비슷하다. 특히 이번 검정에서 육추기간 중 한마리의 폐사도 없는 구는 3구였으며 9구 만이 79.64$\%$로 육추율이 가장 낮았는데 그 원인은 1개 검정소에서 육추기간 중 백혈병으로 인한 폐사수가 많았기 때문으로 보인다. 육성율 평균은 99.07$\%$로서 14회 99.0$\%$와 같았고 한마리의 폐사도 없는 구는 11구로서 최고 육성율을 보였다. 성계 생존율은 평균이 90.14$\%$로서 14회의 92.6$\%$에 비슷 하였으며 13구는 97.98$\%$로서 상당히 좋은 성적을 보였으며 6구, 7구 9구, 10구 및 11구는 90$\%$이하로 성계생존율은 5회 점검 이후 점차 높아 졌는데 이유는 MD백신이 개발되어 이의 접종으로 인한 마렉병의 발생을 예방 할 수 있었던 것으로 생각된다. 2. 성 성숙일령 15회 검정에서 13개 계군의 평균 성 성숙 일령은 163일에서 14회 161일과는 비슷하였는데 성 성숙 일령은 육성기의 사료 급여와 사양관리에 따라서 영향을 많이 받는 형질이므로 더 이상의 고찰이 필요하지 않다. 성 성숙이 제일 빠른구는 5구의 154일이었고 늦은 구는 9구의 168일 이었는데 그 차는 14일이였다. 3. 산란율 및 산란지수 이번 검정계군의 평균 산란율은 70.14$\%$로서 14회에 73.8$\%$와 약 3.6$\%$가 낮았다. 한편 최고 산란율을 나타낸 구는 5구의 73.86$\%$였으며 산란율이 제일 낮은 구는 11구의 65.95$\%$였다. 산란지수의 평균은 232.02로서 14회의 246.5보다는 14.5개가 적었는데 이는 산란율에서와 같은 경향치 였다. 최고 산란 지수를 보인 구는 5구의 250.69였고 2구와 3구, 8구, 13구도 240이상으로서 상당이 좋은 성적을 보였으며 9구는 204.82로서 산란지수가 최하위 였고 최상위와 최하위와의 산란지수의 차이는 무려 45.87이었다. 4. 사료 요구율 13개 계군의 평균사료 요구율은 2.67로서 14회 2.68과 비슷하였다. 사료 요구율이 제일 낮았던구는 3구의 2.56이였고 사료 요구율이 제일 높았던 구는 9구의 2.78이였다. 5. 난중 13개 계군의 평균난중은 60.72g으로서 14회 59.08g보다는 약간 무거웠는데 난중은 다른 형질에 비하여 유전력이 높은 형질인 것을 감안할 때 사양관리 면에서의 영향이 아니고 출품계군의 구성에 의한 영향인 것으로 생각된다. 8회 검정 성적 중 난중이 제일 무거운 구는 4구의 63.32g이었고 제일 가벼운 구는 5구의 58.08g이었다. 6. 체중 300일령 평균체중은 1,966.33.g으로 14회 1,986.7g보다는 가벼웠는데 체중 역시 유전력이 높은 형질로서 이 차이는 검정계군의 구성에 따른 차이로 생각 된다. 500일령 체중의 평균은 1,985.68g으로 14회의 1,994.9g보다는 약간 가벼웠으나 500일령 체중에 있어서와 같이 검정계군의 구성에 따른 차이로 생각 된다. 7. 사료 섭취량 육추기간 중의 1일 1수당 평균사료 섭취량은 32.97g으로 14회 34.82g보다 적었는데 이것 역시 출품계군의 구성에 있어 겸용종 내지 유색종의 비율이 낮았던 데에 기인한 것으로 생각된다. 육성기의 1일 1수당 사료섭취량은 70.06g으로서 14회의 70.91g과 같았고 산란기간 중의 1일 1수당 사료섭취량은 평균이 113,54g으로서 14회 115.81g과 비교할 때 큰 차가 없었으며 특히 11구는 118.61g으로 가장 사료를 많이 섭취 했는데 산란기 수당 사료 섭취량은 해가 거듭될수록 적어지는 경향이었다. 8. 경제성 13개 검정계군이 총 수입은 45,405원으로 계란 판매 수입은 86.4$\%$였고 폐계 판매수입은 13.59$\%$였으며 총 지출은 33,657원으로 사료비의 지출비율이 95.5$\%$였고 초생추대가 4.5$\%$였다.

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Pharmacokinetics of ofloxacin in Patients with Multidrug-Resistant Tuberculosis (다제내성결핵 환자에서 ofloxacin의 약동학적 분석)

  • Park, Seung-Kyu;Yoon, Young-Ran;Lee, Woo-Chul;Jun, Hyung-Min;Shon, Ji-Hong;Kim, Kyoung-Ah;Park, Ji-Young;Shin, Jae-Gook
    • Tuberculosis and Respiratory Diseases
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    • v.52 no.2
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    • pp.128-136
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    • 2002
  • Background: There are few studies that have reported on the pharmacokinetic(PK) disposition of fluoroquinolones in patients with multi-drug resistant tuberculosis(MDR-Tb), even though fluoroquinolones are frequently co-prescribed to those patients. In this study, the PK disposition of ofloxacin, a fluoroquinolone, was evaluated in patients with MD R -Tb. Methods: Twenty patients with MDR-Tb were given 2nd line Tb drugs including ofloxacin (300mg twice a day), prothionamide, cycloserine, para-aminosalicylic acid, kanamycin, and streptomycin. The patients were grouped according to their body mass index(BMI) as an index of emaciation (group A : 18.5$\leq$BMI <23, group B : BMI < 18.5). Blood samples were serially drawn and urine samples were collected upto 24 hours after the last dose of those drugs at steady state (over 1 month). The ofloxacin concentrations were determined using HPLC (High Performance Liquid Chromatography). Results: The AUC of ofloxacin in group B was greater than that in group A ($31.4{\pm}8.9{\mu}g/ml{\cdot}h$ vs. $24.1{\pm}6.2{\mu}g/ml{\cdot}h$)(Check the symbols), (p<0.05). The total clearance(Cl/F) of ofloxacin was $0.16{\pm}0.03$ L/h/kg in group A, and $0.14{\pm}0.03$ L/h/kg in group B. The half-lives of ofloxacin in two groups were similar (group A : $5.3{\pm}0.8$ hours, group B : $5.7{\pm}0.9$ hours). In addition, the other PK parameters in two groups were also similar. Conclusions: The pharmacokinetics of ofloxacin in patients with MDR-Tb appears to be comparable with those of normal subjects, and the extent of emaciation appears to have an influence on the pharmacokinetics of ofloxaicn in chronic debilitated MDR-Tb patients.

Comparison of γ-aminobutyric acid and isoflavone aglycone contents, to radical scavenging activities of high-protein soybean sprouting by lactic acid fermentation with Lactobacillus brevis (발아 고단백 콩의 Lactobacillus brevis 젖산발효에 의한 가바와 이소플라본 함량 및 라디칼 소거활성의 비교)

  • Hwang, Chung Eun;Haque, Md. Azizul;Lee, Jin Hwan;Joo, Ok Soo;Kim, Su Cheol;Lee, Hee Yul;Um, Bong Sik;Park, Kyung Sook;Cho, Kye Man
    • Food Science and Preservation
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    • v.25 no.1
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    • pp.7-18
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    • 2018
  • In this study, soy-powder yogurt (SPY) with enhanced levels of ${\gamma}$-aminobutyric acid (GABA) and isoflavone aglycone was produced from sprouting high-protein soybeans (HPSs). The fermented steam-HPS sprouts (0 to 4 cm) were fermented (72 h) with Lactobacillus brevis, and the total free amino acids (FAAs) of the formed mixtures were determined to be 79.53, 489.93, 877.55, 780.53, and 979.97 mg/100 mL in the fermented HPS (FHPS), and the fermented steam-HPS with 0 cm (FSHPS-0), 1 cm (FSHPS-1), 2 cm (FSHPS-2), and 4 cm sprouting lengths (FSHPS-4), respectively. The levels of glutamic acid (GA) and GABA were observed to be the highest, 100.31 and 101.60 mg/100 mL, respectively, in the unfermented HPS (UFSHPS-1, 1 cm) and FSHPS-1 sprouts, respectively. Moreover, the total contents of the isoflavone glycoside form decreased proportionally to the increasing total levels of isoflavone aglycones after fermentation in FSHPS-0, FSHPS-1, FSHPS-2, and FSHPS-4. The levels of isoflavone aglycones were detected as 350.34, 289.15, 361.61, 445.05, and $491.25{\mu}g/g$ in FHPS, FSHPS-0, FSHPS-1, FSHPS-2, and FSHPS-4, respectively. While FSHPS-1 exhibited the highest DPPH (63.28%) and ABTS (73.28%) radical scavenging activities, FSHPS-4 contained the highest isoflavone aglycone ratio (81.63%). All in all, the FSHPS-1 mixture prepared in this study exhibited high GABA content and functional prosperity, thereby making it suitable for potential applications in the soy-dairy industry.

Response of the Growth Characteristics and Phytochemical Contents of Pepper (Capsicum annuum L.) Seedlings with Supplemental LED Light in Glass House (LED 보광처리가 고추(Capsicum annuum) 묘의 생장과 Phytochemical 함량에 미치는 영향)

  • Azad, Md. Obyedul Kalam;Chun, Ik-Jo;Jeong, Jeong-Hak;Kwon, Soon-Tae;Hwang, Jae-Moon
    • Journal of Bio-Environment Control
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    • v.20 no.3
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    • pp.182-188
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    • 2011
  • This research was conducted to evaluate the effect of supplemental light-emitting diode (LED) light on growth characteristics and phytochemical content of pepper (Capsicum annuum L.) seedling using LED blue (470 nm, B), red (660 nm, R), blue + red (BR), far red (740 nm, FR) and UV-B (300 nm) light treatment, and without artificial light. Photon flux of LED light was 49, 16, 40, 5.0 and $0.82{\mu}mol\;m^{-2}s^{-1}$ for B, R, BR, FR, and UV-B light, respectively, during experiment. Supplemental LED light duration was $16hr\;day^{-1}$ and UV-B light duration was 10 min. per day after sunset up to 15 days (12 days after germination) of plants age. In our research, growth characteristics and phytochemical content of pepper seedlings were greatly influenced by supplemental LED light compare to control treatment. Red light increased the number of leaves, number of nodes, leaf width and plant fresh weight by 34%, 27%, 50% and 40%, respectively. Blue light increased the leaf length by 13%, and stem length and length of inter node were increased by 17% and 34%, respectively under grown far red light. After 15 days of light treatments phytochemical concentrations of pepper plants were significantly changed. Blue light enhanced the total anthocyanin and chlorophyll concentration by 6 times and 2 times, respectively. Red light increased the total phenolic compound at least two folds meanwhile far red light reduced the ascorbic acid and antioxidant activity 31% and 66%, respectively compared to control treatment.

Effect of Nandrolone Decanoate on Disuse Muscle Atrophy and Bone Beating in Dogs (개에서 불용성 근위축과 골절 치유에 대한 Nandrolone decanoate의 효과)

  • Yun Seong-jin;Lim Ji-hey;Rahman Md. Mizanur;Byeon Ye-eun;Kim Wan-hee;Kweon Oh-kyeong
    • Journal of Veterinary Clinics
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    • v.22 no.4
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    • pp.336-341
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    • 2005
  • Anabolic steroid compounds are widely used for the increase of muscle mass, density of bone and athletic ability. The present study conducted to evaluate the effects of nandrolone decanoate (ND), one of the anabolic steroid compounds, on disuse muscle atrophy and healing process of bone in dogs. Twenty physically healthy dogs of both sexes were used in this experiment and divided into three groups: group A (control), group B (low dose M-1.5 mg/kg) and group C (high dose ND-7.5 mg/kg). One-mm strip of full thickness bone was excised from the radius below the pronator teres muscle for the artificial fracture and then the fractured ends were fixed in apposition with bone plate leaving 1mm gap, and finally immobilized externally by Robert John's bandage for 4 weeks. ND was administered intramuscularly once a week far 8 weeks. Body weight, muscle mass change and fracture gap of the bone were evaluated immediately after surgery, and 2, 4, and 8 weeks after surgery. The rates of muscle mass change 8 weeks after surgery were $-2.75\pm0.16\%,\;1.68\pm0.11\%\;and\;1.74\pm0.48\%$ in groups A, B and C, respectively. The significant increase (p<0.05) of muscle mass increments were found in the treated groups. The fibrous connective tissue layer in the fracture gaps of the treated groups increased more than the control, especially in the group C at 4th week. More dense fibrous connective tissue were found in the treated groups at 8th week. Collectively, our results suggested that ND was an effective anabolic agent for the immobilized disuse muscle and bone healing.

A MORPHOMETRIC STUDY ON THE PREFORMED STAINLESS STEEL CRORWNS OF SOME BRANDS (유치용 수종 기성금속관의 형태에 대한 계측학적 연구)

  • Han, Eun-Ok;Lee, Ji-Hyun;Kim, Shin;Jeong, Tae-Sung
    • Journal of the korean academy of Pediatric Dentistry
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    • v.39 no.2
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    • pp.145-152
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    • 2012
  • Whenever pediatric dentists choose the preformed stainless steel crowns for restoration of primary molars, we usually prefer the crown forms that most fit to the abutment teeth. Despite some previous reports on significant ethnic difference in the size and shape of tooth crowns in primary dentition, only the imported products have been available to date, which might show some discrepancy with tooth anatomy of Korean. However, a domestic product of preformed stainless steel crown has been marketed recently that is expected to show more accurate fit to the primary tooth of Korean. To investigate the morphological characteristics of primary molars of Korean children, their mesiodistal and buccolingual diameters from the dental casts of 263 children in Pusan and Kyungsangnamdo province were measured by digital calipers. The measured data were compared with those of the three types of preformed stainless steel crowns(3M ESPE Stainless Steel Primary Molar Crown, Kids Crown, Sankin Anatom Primary Crown) by statistical processes with regression analysis. The results were as follows: 1. In every primary molar crown of three brands, the bucco-lingual width to mesio-distal width ratio (MD-BL ratio) showed higher values compared with those of natural teeth. 2. While the products of 3M ESPE and Shinhung showed similar features, those of Sankin showed some difference from both, and these difference was more marked in mandibular primary molars. 3. The nearer is the mesio-distal width of the crown to the average, the better was the adaptation of the preformed crown, and the reverse was true. 4. The teeth which revealed more discrepancy between preformed crown and natural tooth were upper and lower first primary molars.

An Exploratory Empirical Study on Shopping Choice in Retail Channels by the Selective Characteristics of Foods (상품 선택 특성에 따른 쇼핑채널 선택에 관한 연구: 식품 MD를 중심으로)

  • Ha, Kwang-Ok;Lee, Jung-Hee
    • The Journal of Small Business Innovation
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    • v.20 no.1
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    • pp.35-46
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    • 2017
  • The purpose of this study is to obtain the implications for establishing a marketing strategy for retailers by analyzing whether the consumer's preference for products (food) is influenced by on-line, off-line, and omni-channel preferences. The research model consisted of the effects of consumers' food selection characteristics on business preference and omni channel preference. The results of analysis based on 477 questionnaires are summarized as follows. First, food purchasing characteristics that utilize the seven characteristics of (1) freshness of food, (2) taste, (3) quality and safety, (4) tasting, (5) food function and information, (6) country of origin, and (7) brand loyalty, has various effects on types of business preference, omni-channel preference. The adopted hypotheses were selected in order of brand loyalty (5 times), freshness (3 times), tasting (3 times), and origin (1 time). The selective attributes on foods are: (1) what kind of brand, (2) how good the freshness is, (3) tasting. (4) The country of origin is to be compressed. Actually consumers seem to utilize only the core selective factors that are appropriate to the characteristics of the distribution channel rather than all of them in the shopping of the food, and there is three characteristics on Convenience Store and only one or two factors in the other types of business. Second, in the analysis of the omni-channel preference analysis, food selection characteristics has been shown to have a limited effect, which is attributed to the fact that the consumer has not yet understood the concept of omni channel. Third, the results of this study suggest that there is a need to reflect the selection characteristics of foods that have diverse influences by business type in the marketing strategies. Because consumers make reasonable consumption to use both on-line and off-line simultaneously, consumers who use Omni Channel focus on quality and safety of food, identify products through tasting, pursue brands that can trust anywhere. Customers who pursue rationality will have a high preference for using Omni Channel. Product choice characteristic has significant effect on omni-channel preference. For a few years, omni-channel strategy of retailers meets with a difficulty. This study make a first attempt to study omni-channel preference changing retailing paradigm.

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Henoch-$Sch{\ddot{o}}nlein$ Nephritis in Children (소아 Henoch-$Sch{\ddot{o}}nlein$ 신염의 추적 관찰)

  • Jang, Hee-Suk;Hong, In-Hee;Go, Cheol-Woo;Koo, Ja-Hun;Kwak, Jung-Sik
    • Childhood Kidney Diseases
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    • v.4 no.2
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    • pp.120-126
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    • 2000
  • Purpose : This retrospective study has been undertaken to find out the clinical outcome of children with HS nephntis and its relationship with initial clinical presentation and/or renal pathologic finding. Patients and methods : Study population consisted of 59 children with HS nephritis who have been admitted to the Pediatric department of Kyungpook University Hospital from 1987 to 1999, and biopsy was done with indications of heavy proteinuria (> 1 g/m2/day) lasting over 1 month, nephrotic syndrome, and persistent hematuria and/or proteinuria over 1 year. Patients were divided clinically into 3 groups ; isolated hematuria, hematuria with proteinuria and heavy proteinuria (including nephrotic syndrome). Biopsy findings ore graded from I-V according to International Study of Kidney Disease in Children (ISKDC). Results : Mean age of presentation was $8.1{\pm}3.0$ years and slight male preponderance m noted (33 boys md 26 girls). Histopathologic grading showed Grade I ; 2, Grade II ; 44, and Grade III ; 13 cases. Clinical outcome at the follow-up period of 1-2 year (49 cases) and 3-4 years (30 cases) shooed normal urinalysis in 75 (30.6$\%$) and 18 cases (60.0$\%$), persistent isolated hematuria in 20 (40.8$\%$) and 2 cases (6.7$\%$), hematuria with proteinuria in 11 (22.5$\%$) and 8 cases (26.6$\%$), and persistent heavy proteinuria in 3 (6.1$\%$) and 2 cases (6.7$\%$) respectively. Clinical outcome according to histopathologic grading showed the frequency of normalization of urinalysis being lower in Grade III compared to grade I or II. Clinical outcome according to initial clinical presentation showed no relationship to the normalization or urinalysis at follow-up periods. However, 15-20$\%$ of children with initial heavy proteinuria showed persistent heavy proteinuria (3 out of 20 cases at 1-2 years, and 2 out of 10 case at 3-4 years of follow-up periods). Conclusion : The majority of children with HS nephritis (histopathologic grade I, II, III) improved within 3-4 years and persistent heavy proteinuria was seen only in a kw of children with initial clinical presentation of heavy proteinuria.

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THE EFFECTS OF CRYSTAL GROWTH ON SHEAR BOND STRENGTH OF ORTHODONTIC BRACKET ADHESIVES TO ENAMEL SURFACE (Crystal growth에 의한 법랑질 표면처리가 교정용 브라켓 접착제의 전단결합강도에 미치는 영향)

  • Lee, Young-Jun;Park, Young-Guk
    • The korean journal of orthodontics
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    • v.27 no.5 s.64
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    • pp.839-852
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    • 1997
  • It has been submitted that different ion solutions containing sulfate induce crystal growth and might substitute conventional acid etching for pretreatment of enamel in orthodontic bonding(${\AA}rtun$ et al., Am. J. Orthod. 85, 333, 1984). This investigation was designed to evaluate the relevance of crystal growth on the enamel surface as an alternative to conventional acid etching in direct bonding of orthodontic brackets. Annexing Li2SO4, MgSO4, K2SO4 respectively in the solution with $25\%$ polyacrylic md 0.3M sulfuric acids were employed to enhance the crystal growth. Human bicuspids were treated with various parameters as combinations of crystal growth and glass ionomer cement, crystal growth and orthodontic resin, acid etching and orthodontic resin for an investigative purpose. Crystal growth solution containing MgSO4 showed the highest shear bond strength(15.6MPa) within the groups of bonding brackets with glass ionomer cement(p<0.01). Bonding with glass ionomer cement on the surface of crystal growth demonstrated higher shear bond strength than with orthodontic resin(p<0.001). Bonding with glass ionomer cement on the surface treated with crystal growth solution containing MgSO4 or K2SO4 was not different shear bond strength statistically from bonding with orthodontic resin on the acid-etched surface. It suggests that bonding brackets with glass ionomer cement on the surface treated with crystal growth solution containing MgSO4 or K2SO4 is a potential alternative to bonding with resin on the acid etched sufrace.

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The nanoleakage patterns of experimental hydrophobic adhesives after load cycling (Load cycling에 따른 소수성 실험용 상아질 접착제의 nanoleakage 양상)

  • Sohn, Suh-Jin;Chang, Ju-Hae;Kang, Suk-Ho;Yoo, Hyun-Mi;Cho, Byeong-Hoon;Son, Ho-Hyun
    • Restorative Dentistry and Endodontics
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    • v.33 no.1
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    • pp.9-19
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    • 2008
  • The purpose of this study was: (1) to compare nanoleakage patterns of a conventional 3-step etch and rinse adhesive system and two experimental hydrophobic adhesive systems and (2) to investigate the change of the nanoleakage patterns after load cycling. Two kinds of hydrophobic experimental adhesives, ethanol containing adhesive (EA) and methanol containing adhesive (MA), were prepared. Thirty extracted human molars were embedded in resin blocks and occlusal thirds of the crowns were removed. The polished dentin surfaces were etched with a 35 % phosphoric acid etching gel and rinsed with water. Scotchbond Multi-Purpose (MP), EA and MA were used for bonding procedure. Z-250 composite resin was built-up on the adhesive-treated surfaces. Five teeth of each dentin adhesive group were subjected to mechanical load cycling. The teeth were sectioned into 2 mm thick slabs and then stained with 50 % ammoniacal silver nitrate. Ten specimens for each group were examined under scanning electron microscope in backscattering electron mode. All photographs were analyzed using image analysis software. Three regions of each specimen were used for evaluation of the silver uptake within the hybrid layer. The area of silver deposition was calculated and expressed in gray value. Data were statistically analyzed by two-way ANOVA and post-hoc testing of multiple comparisons was done with the Scheffe's test. Silver particles were observed in all the groups. However, silver particles were more sparsely distributed in the EA group and the MA group than in the MP group (p < .0001). There were no changes in nanoleakage patterns after load cycling.