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Comparison of Bone Volume Measurements Using Conventional Single and Dual Energy Computed Tomography (전산화단층영상검사에서 단일에너지와 이중에너지를 이용한 뼈 부피측정의 비교)

  • Kim, Yung-kyoon;Park, Sang-Hoon;Kim, Yon-Min
    • Journal of radiological science and technology
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    • v.40 no.2
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    • pp.253-259
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    • 2017
  • The study examines changes in calcium volume on born by comparing two figures; one is measured by dual energy computed tomography(DECT) followed by applying variation in monochromatic energy selection(keV), material decomposition(MD), and material suppressed iodine(MSI) analysis, and the other is measured by conventional single source computed tomography(CSCT). For this study, based on CSCT images taken by using human mimicked phantom, 70, 100, 140 keV and MSI, MD material calcium weighting(MCW) and MD material iodine weighting(MIW) of DECT were applied respectively. Then calculated calcium volume was converted to Agatston score for comparison. Volume of human mimicked phantom was in inverse proportion to keV. The volume decreased while keV increased(p<0.05). The most similar DECT volumes were reconstructed at 70 keV, the difference was showed $35.8{\pm}12.2$ for rib, femur ($16.1{\pm}24.1$), pelvis($13.7{\pm}18.8$), and spine($179.0{\pm}61.8$). However, the volume of MSI was down for each organ; the volume of rib was 5.55%, femur(76.34%), pelvis(55.16%) and spine(87.58%). The volume of MSI decreased 55.9% for rib, femur(80.7%), pelvis(69.6%) and spine(54.2%) while MD MIW reduced for rib(83.51%), femur(87.68%), pelvis(86.64%), and spine(82.62%). With the results, the study found that outcomes were affected by the method which examiners employed. When using DECT, calcium volume of born dropped with keV increased. It also found that the most similar DECT images were reconstructed at 70 keV. The results of experiments implied that the users of MSI and MD should be cautious of errors as there are big differences in scores between those two methods.

Repeated-Dose Toxicity Study of Pediococcus pentosaceus MD1, an Anti-Helicobacter pyroli Activity Lactic Acid Bacteria Isolated from Kimchi, in Rats (김치로부터 분리한 Helicobacter pyroli 억제능 유산균 Pediococcus pentosaceus MD1의 흰쥐에 대한 반복투여독성 연구)

  • Lee, Jae-Joon;Lee, Yu-Mi;Chang, Hae-Choon;Lee, Myung-Yul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.36 no.8
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    • pp.975-982
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    • 2007
  • The purpose of this study was to investigate repeated-dose toxicity in male and female rats orally administered with Pediococcus pentosaceus MD1, an anti-Helicobacter pyroli producing lactic acid bacteria isolated from kimchi. Sprague-Dawley rats were divided into 4 groups, 10 animals in each group. The test article was administered once daily by gavage to rats at dose levels of 0, 500, 1,000 and 2,000 mg/kg for 4 weeks. No test article-related deaths and clinical findings in both sexes of rats during the study period were resulted. In addition, no differences were found between control and treated groups in body weight changes, food intake consumption and water consumptions. Hematological parameters, serum biochemical analysis and any other findings did not also show any significant or dose-dependent alterations. There were no alterations in absolute and relative organ weights by the administration of Pediococcus pentosaceus MD1. These results suggest that no-observed-adverse-effect level (NOAEL) of Pediococcus pentosaceus MD1 is considered to be more than 2 g/kg in male and female rats.

Fourier Transform Infrared Spectroscopic Studies of Hydrothermal Illites (열수변질 기원 일라이트의 FTIR 연구)

  • 추창오;김수진
    • Journal of the Mineralogical Society of Korea
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    • v.13 no.1
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    • pp.37-43
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    • 2000
  • Fourier transform 적외선 분광기를 사용하여 원적외선 (<200 cm-1) 영역과 중간적외선 (400-4000 cm-1) 영역에서 열수기원 일라이트의 층간 결합상태와 화학조성간의 관계를 해석하였다. 중간 적외선 영역에서는 2M1 다형의 Al-O-Al 및 Al-O-Si 결합이 1Md 형의 것보다 강한 것으로 나타났다. 원적외선 영역에서는 세 종류의 K-O 결합이 111-114, 135-143 및 167-168 cm-1에서 인지되었다. 2M1과 1Md 다형간의 가장 큰 차이는 2M1형의 층간결합이 1Md형보다 상대적으로 강하여 K가 층간에 보다 강하게 결합되어 있다는 점이며, 두 다형의 층간결합의 상태는 서로 상이하다. K-Oinner band는 (OH) stretching band의 진동수가 높을수록 커지며, (OH) stretching band는 팔면체의 양이온 (Fe+Mg)의 함량에도 영향을 받는 것으로 나타났다.

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Clinical Features of Deep Neck Infections and Predisposing Factors for Mediastinal Extension

  • Kang, Shin-Kwang;Lee, Seok-Kee;Oh, Hyun-Kong;Kang, Min-Woong;Na, Myung-Hoon;Yu, Jae-Hyeon;Koo, Bon-Seok;Lim, Seung-Pyung
    • Journal of Chest Surgery
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    • v.45 no.3
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    • pp.171-176
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    • 2012
  • Background: Deep neck infections (DNI) can originate from infection in the potential spaces and fascial planes of the neck. DNI can be managed without surgery, but there are cases that need surgical treatment, especially in the case of mediastinal involvement. The aim of this study is to identify clinical features of DNI and analyze the predisposing factors for mediastinal extension. Materials and Methods: We reviewed medical records of 56 patients suffering from DNI who underwent cervical drainage only (CD group) and those who underwent cervical drainage combined with mediastinal drainage for descending necrotizing mediastinitis (MD group) from August 2003 to May 2009 and compared the clinical features of each group and the predisposing factors for mediastinal extension. Results: Forty-four out of the 56 patients underwent cervical drainage only (79%) and 12 patients needed both cervical and mediastinal drainage (21%). There were no differences between the two groups in gender (p=0.28), but the MD group was older than the CD group (CD group, $44.2{\pm}23.2$ years; MD group, $55.6{\pm}12.1$ years; p=0.03). The MD group had a higher rate of co-morbidity than the CD group (p=0.04). The CD group involved more than two spaces in 14 cases (32%) and retropharyngeal involvement in 12 cases (27%). The MD group involved more than two spaces in 11 cases (92%) and retropharyngeal involvement in 12 cases (100%). Organism identification took place in 28 cases (64%) of the CD group and 3 cases of (25%) the MD group (p=0.02). The mean hospital stay of the CD group was $21.5{\pm}15.9$ days and that of the MD group was $41.4{\pm}29.4$ days (p=0.04). Conclusion: The predisposing factors of mediastinal extension in DNI were older age, involvement of two or more spaces, especially including the retropharyngeal space, and more comorbidities. The MD group had a longer hospital stay, higher mortality, and more failure to identify causative organisms of causative organisms than the CD group.

Perforation of Meckel's Diverticulum in Children (소아에서 발생한 천공성 메켈게실)

  • Ghil, Tae-Hwan;Yun, Jung-Hoon;Kim, Sang-Woo;Huh, Young-Soo
    • Advances in pediatric surgery
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    • v.8 no.1
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    • pp.28-32
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    • 2002
  • Meckel's diverticulum (MD) occurs in approximately 2 % of the population. The major complications of MD are bleeding, intestinal obstruction, infection and perforation. Perforation is the least common but most serious complication, the incidence od which is about 5-10 %. The causes of perforation are inflammatory diverticulitis and peptie ulceration. the purpose of study is to review the characteristics of perforated MD in children. Six patients with perforated MD who had been operated upon at the Department of Pediatric Surgery, Yeungnam University Hospital from April 1984 to July 2001 were included. Male predominated in a ratio of 5:1 and there were 2 neonates. The chief complaints were abdominal pain and distension. Half of the children showed a past history of bloody stools. The average age was 4 year and 9 months. The mean distance from the ileocecal valve to the diverticulum was 60 cm. Average length of the diverticulum was approximately 3 cm and width was 1.7 cm. The perforation site was the tip of the diverticulum in 3 cases, the base in 2 cases and along the lateral border in one. In two patients, ectopic gastric mucosa was found in the specimen. All of the patients were operated upon with a diagnosis of peritonitis of unknown etiology. In conclusion, when a child shows symptoms of acute abdomen or peritonitis, especially in boys, with the history of bloody stools and episodic abdominal pain, perforated MD should be suspected.

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Duration Magnitude and Local-Duration Magnitude Relations for Earth-quakes of 1979-1998 Recorded at KMA Network (한반도 지진의 지속규모식에 관한 연구)

  • 박삼근
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 1998.10a
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    • pp.421-435
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    • 1998
  • An empirical formula for estimating duration magnitude(MD)is determined by analyzing 619 epicentral distance-duration data set, obtained from earthquakes of 1989-1998 recorded at the KMA network. Based on two assumptions: 1) observed signal duration decreases with increasing epicentral distance, and 2) seismographs of KMA are set at low-gain and therefore inclusion of sensitivity correction term in the equation is not necessary, scaling predicted duration at epicenter to Tsuboi's local magnitude yielded the duration magnitude equation: MD =2.0292$\times$log$\tau$+0.00123Δ-1.4017 for 1/0$\leq$ML$\leq$5.0, where $\tau$is total signal duration(sec)and Δis epicentral distance(km). Event by event comparison of ML values against MD estimates for t152 events shows that for events having a same ML the difference in MD estimates reaches as high as 1.1 magnitude units. So, to test the usefulness of the duration magnitude equation, we have calculated ML-MD relations by which duration magnitude estimates are converted to local magnitudes ("predicted" ML, say) which are then compared with the directly determined local magnitude values. Except for events with stations where duration is anomalously reestimates(predicted ML) which are in an agreement within a 0.2 magnitude units with the corresponding ML values. Although this study could gain some insights into magnitudes of the past events, we still need to re-examine all the observables in order to obtain more reliable and precise information about magnitude and hypocenter location. So we will pursue a new local-magnitude scaling, as well as refinement of the duration magnitude equation, starting soon with re-reading the amplitudes-arrival time records of (and hence relocating) 250+earthquakes of 1979-present recorded at the KMA network. Thus, with more reliable and precise earthquake parameters determined we would better understand the recent seismicity and related tectonic process within and adjacent region to the Korean peninsula.peninsula.

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Draft Genome Sequence of Mycobacterium abscessus Treated with a Fluoroquinolone in a Time-Dependent Manner

  • Du-Gyeong Han;Ji-A Jeong;Sung-Kyoung Lee;Seong-Han Kim;Se-Mi Jeon
    • Microbiology and Biotechnology Letters
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    • v.52 no.2
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    • pp.211-214
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    • 2024
  • This study aimed to confirm the induction of resistance to other drug classes by treating Mycobacterium abscessus with moxifloxacin, a fluoroquinolone used for treating nontuberculous mycobacteria infection, and to obtain genetic data for improving treatment. The reads were assembled and analyzed using reference strain sequence data, and the whole-genome and transcriptome sequences of four strains (MD2, MD4, MD6, and MD8) were reported. Antibiotic resistance was not induced by moxifloxacin treatment; however, transcriptomic analysis revealed that the expression of genes responding to stress was upregulated.

Na Borosilicate Glass Surface Structures: A Classical Molecular Dynamics Simulations Study (소듐붕규산염 유리의 표면 구조에 대한 분자 동역학 시뮬레이션 연구)

  • Kwon, Kideok D.;Criscenti, Louise J.
    • Journal of the Mineralogical Society of Korea
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    • v.26 no.2
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    • pp.119-127
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    • 2013
  • Borosilicate glass dissolution is an important chemical process that impacts the glass durability as nuclear waste form that may be used for high-level radioactive waste disposal. Experiments reported that the glass dissolution rates are strongly dependent on the bulk composition. Because some relationship exists between glass composition and molecular-structure distribution (e.g., non-bridging oxygen content of $SiO_4$ unit and averaged coordination number of B), the composition-dependent dissolution rates are attributed to the bulk structural changes corresponding to the compositional variation. We examined Na borosilicate glass structures by performing classical molecular dynamics (MD) simulations for four different chemical compositions ($xNa_2O{\cdot}B_2O_3{\cdot}ySiO_2$). Our MD simulations demonstrate that glass surfaces have significantly different chemical compositions and structures from the bulk glasses. Because glass surfaces forming an interface with solution are most likely the first dissolution-reaction occurring areas, the current MD result simply that composition-dependent glass dissolution behaviors should be understood by surface structural change upon the chemical composition change.

Effects of Exercise-Based Intervention Before and After Lung Cancer Surgery: A systematic review in pubmed database (허파암 수술 전과 후에 적용한 운동의 효과: PubMed 내 연구에 대한 체계적 문헌고찰)

  • Boram Oh;Heesu Kim;Sookyoung Park
    • Journal of The Korean Society of Integrative Medicine
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    • v.11 no.2
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    • pp.23-35
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    • 2023
  • Purpose : Lung cancer induces a decrease in physical activity and a deterioration of respiratory ability. Exercise is an effective treatment to reduce side effects of anti-cancer treatments, also influence the survival and successful rehabilitation in lung cancer patients. However, there is insufficient evidence to show which period is the most effective to apply exercise for lung cancer patients. Therefore, this study was conducted to evaluate the efficacy of exercise-based interventions before and after surgery. Methods : Clinical trials (CTs) and randomized controlled trials (RCTs) reported in PubMed database were investigated. The trials investigated in this study were published for 10 years before August 20, 2022. The risk of bias was judged according to the Cochrane guideline. The materials included in this meta-analysis were 6-minute walk test (6MWT), pulmonary function, and quality of life (QOL). Results : 1 CT and 9 RCTs were selected in current study. In the meta-analysis, exercise increased 6MWT in preoperation (mean difference [MD] 29.49; 95 % confidence interval [CI] .99 to 57.99; p=.04; I2=0 %), 3 months postoperation (MD 54.97; 95 % CI 31.85 to 78.09; p<.001; I2=45 %) and 6 months postoperation (MD 85.59; 95 % CI 45.06 to 126.12; p<.001; I2=47 %). Exercise, also enhanced the lung function such as FEV1/FVC (%) in postoperation (MD 7.64; 95 % CI 6.26 to 9.02; p<.001; I2=19 %). Additionally, exercise improved QOL, such as preoperative EORTC-QLQ-C30-LC13 in mental function (MD 3.21; 95 % CI .64 to 5.79; p=.01; I2=0 %) and postoperative SF-36 in mental component summary (MD 9.24; 95 % CI 4.94 to 13.54; p<.001; I2=0%). Conclusion : These results indicate that exercise-based intervention can elevate the ability to exercise and the mental componentof QOL within 3 months.

Mineralogy and Genesis of Hydrothermal Deposits in the South-eastern Part of Korean Peninsula:(2) Bobae Sericite Deposits (우리나라 동남부 지역의 열수광상에 대한 광물학적 및 광상학적 연구:(2) 보배견운모 광상)

  • 김수진;추창오;박희인;노진환
    • Journal of the Mineralogical Society of Korea
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    • v.4 no.2
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    • pp.129-140
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    • 1991
  • Two illite polytypes, 2M1 and 1Md, have been identified from the sericite deposits of the Bobae mine, Kimhae, Kyungsangnam-do. Each polytype has characteristic grain size, chemical composition, and occurrence. 2M1 illite occurs predominantly in the sericitic alteration zone, while 1Md illite occurs predominantly in the propylitic alteration zone, implying that the former was formed in the higher temperature than the latter. Illites can be subdivided into two types based on their crystal sizes;(1) the $\mu\textrm{m}$-sized illite which is below 0.01mm(100$\mu\textrm{m}$) in size and consists of 2M1 and 1Md type, (2) the mm-sized illite which is above 0.01mm in size and consists only of 2M1 type. Especially illite below 1$\mu\textrm{m}$ is premominantly of 1Md type. Therefore, it seems likely that illite crystal size is to some extent related to the polytype. XRD data show that there is no interstratified layer in illites regardless of the crystal size and polytype. Activity of muscovite component of the $\mu\textrm{m}$-sized illite is 0.843 while that of the mm-sized illite is 0.790. However, the latter is more similar to muscovite in crystal structure than the former is. The mm-sized illite has less Al and more Kthan the $\mu\textrm{m}$-sized illite. In both illites, Si contents show a positive relation to octahedral Mg. Fluid inclusion study and mineral association show that the formation temperature of illite is $270-330^{\circ}C$. The major chemical processes leading to the formation of sericitic deposit as well as the alteration zones are the leaching of SiO2 from the country rock and the addition of Al2O3 and K2O into the sericitic ores.

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