Kim, Dong-Keun;Ahn, Chi-Hyuk;Hwang, Mi-Jin;Lee, Yeon-Hee;Kang, Soo-Kyung;Auh, Q-Schick;Hong, Jung-Pyo;Chun, Yang-Hyun
Journal of Oral Medicine and Pain
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v.41
no.2
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pp.61-71
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2016
Purpose: This study was designed to evaluate the comparison between the subjective and the objective evaluation of pain control effect in masticatory muscle pain depending on time and dose change. Methods: The patients were recruited to this study and diagnosed according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Experimental group were divided into three groups; saline injection group (n=10), morphine 1.5 mg injection group (n=10), and morphine 3.0 mg injection group (n=10). Evaluation list was the subjective pain evaluation (visual analogue scale, McGill pain questionnaire) and the objective pain evaluation (pressure pain threshold [PPT], pressure pain tolerance [PTO]). The subjective and the objective pain evaluation were performed at the times of just before injection, 10 minutes, 30 minutes, 1 hour, 24 hours, and 48 hours after injection. Then, data were statistically analyzed. Results: The results were as follows: 1) There is no statistically significant difference between the results of the subjective and the objective pain evaluation with regard to the short-term (within 1 hour) analgesic effect of morphine sulfate. 2) However, after 1 hour of injection, while the subjective pain evaluation score still decreased, the objective pain evaluation didn't show significant changes in PPT and PTO (1 hour, p<0.05; 24 hours, p<0.01; 48 hours, p<0.001). 3) In comparison to changes in the dose, the McGill pain questionnaire was the most statistically effective method among the subjective pain evaluations (1.5 mg, p<0.05; 3 mg, p<0.01). Conclusions: Therefore, it was revealed that the subjective pain evaluation was more effective to evaluate long-term pain control, and that the McGill pain questionnaire could be an effective way to evaluate pain control depending on dose changes. It requires further investigations with time and dose extension.
This study proposed new instance selection using neural network with weighted fuzzy membership functions(NEWFM) based on Takagi-Sugeno(T-S) fuzzy model to improve the classification performance. The proposed instance selection adopted weighted average defuzzification of the T-S fuzzy model and an interval selection, same as the confidence interval in a normal distribution used in statistics. In order to evaluate the classification performance of the proposed instance selection, the results were compared with depending on whether to use instance selection from the case study. The classification performances of depending on whether to use instance selection show 77.33% and 78.19%, respectively. Also, to show the difference between the classification performance of depending on whether to use instance selection, a statistics methodology, McNemar test, was used. The test results showed that the instance selection was superior to no instance selection as the significance level was lower than 0.05.
In comparison with the long and continuous his-tory of research in the general area of stress and coping, theoretical and clinical interest in family stress and adaptation is a recent phenomenon. To understand the phenomena of family behavior, a comprehensive theoretical framework is needed to us provide an adequate background to for research. This study was designed to develop and test a hypothetical model for family stress and adaptation in families with handicapped children. A hypothetical model was constructed on the basis of the family stress theory developed by McCubbin etc. The model included six paths. For the purpose of model testing, empirical data was collected from May to August, 1992. The subjects of the study were 190 parents of chidren in five special schools and one private institute in Seoul and Choong Nam. An SPSS P $C^{+}$ and PC-LISREL 7.13 computer programs were used for descriptive and covariance structure analysis. The results of the study are as follows. (1) Family Stress(${\gamma}$$_{3l}$=-.288, T=-4.942) had a direct effect on Family Adaptation. (2) Family Functioning ($\beta$$_{21}$=-.373, T=5.595) had a direct effect on Situational Definition. (3) Family Functioning ($\beta$$_{31}$ =.334, T=5.375) had a direct effect on Family Adaptation. (4) Situational Definition( a2=.270, T=4.285) had a direct effect on Family Adaptation The model was supported by the empirical data. Thus it is suggested that the model could be adequately applied to family nursing care of families with a mentally handicapped child. In particular, the nursing interventions that enhance family functioning and the situational definition would improve family adaptation in families with mentally handicapped children.n.n.
Purpose: This study was to examine effects of muscle electric stimulation on chronic knee pain, activities of daily living, and living satisfaction for Korean elderly women. Methods: The design was a nonequivalent control group pretest-posttest study. Subjects were 60 (experimental: 30, control: 30) elderly women 65 years old or above with good orientation and communication. The experimental treatment was electric stimulation on both thigh quadriceps muscles for 15 minutes per time, 3 times per week, for a total of 12 weeks. Measures were the S-F McGill Pain Questionnaire and Arthritis Impact Measurement Scale for chronic knee pain, activities measurement of daily living for activities of daily living, and living satisfaction measurement for living satisfaction. Data was analyzed through the SPSS Win 12.0. Results: Chronic knee pain by S-F MPQ (t=43.563, p=.000) and chronic knee pain by AIMS (t=31.364, p=.000) were significantly decreased in the experimental group, and the activities of daily living (t=124.353, p=.000) and living satisfaction (t=71.268, p=.000) were significantly increased in the experimental group for Korean elderly women. Conclusion: Muscle electrical stimulation decreased chronic knee pain, and increased the activities of daily living and living satisfaction for Korean elderly women. Further studies for muscle electric stimulation need to be done.
This study was designed to develop and lest a structural model for paternal adaplation and family stress in the families with the handicapped children. A hypothetical model was constructed on the basis of family stress theory developed by McCubbin etc. The model included 6 theoretical concepts and 11 paths. For the purpose of the model testing, empirical data were collected from May to August, 1992. The subject of the study constituted 190 mothers whose children admitted in the five special schools and one privale institutes in Seoul and Choong Nam. In data analysis, SPSS PC+ and PC-LISREL 7.13 computer program were utilized for descriptive and covariance structure analysis. The results of lhe study were as follows. (1) Hypothetical model showed a good fit to the empirical data [Chi-square = 21.19 (df = 7, P = o. 003), Goodness of Fit Index=O.986, Adjusted Goodness of Fit Indes=0.946, Root Mean Square lesidual=0.048), Non Normed Fit Index = 0.80, Normed Fit Index=0.91]. (2) The results of Hypothesis testing indicated: 1) Social support(${\gamma}_11=.238$, T=2.352), Family Functioning(${\gamma}_12=.729$, T=5.957) had direct effects on situational definition. 2) life event stress(${\gamma}_23=.284$, T=5.220) had direct effects on the effect of the handicapped chid on the family. 3) Family functioning(${\gamma}_32=-.239$, T= -3.370) had direct effects on paternal adapation. From the above results, the significance of this study can be delineated as follows : The construction and testing of the comprehensive model seem to be the first trial in Korea. The model was supported by empirical dala. Thus it was suggested that model could be adequately applied to framily nusing care with the handicapped.
Yu Zhang;Woocheol Kwon;Ho Yun Lee;Sung Min Ko;Sang-Ha Kim;Won-Yeon Lee;Suk Joong Yong;Soon-Hee Jung;Chun Sung Byun;JunHyeok Lee;Honglei Yang;Junhee Han;Jeanne B. Ackman
Korean Journal of Radiology
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v.22
no.5
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pp.829-839
/
2021
Objective: To compare the diagnostic performance of contrast-enhanced radial T1-weighted gradient-echo 3-tesla (3T) magnetic resonance imaging (MRI) and computed tomography (CT) for the detection of visceral pleural surface invasion (VPSI). Visceral pleural invasion by non-small-cell lung cancer (NSCLC) can be classified into two types: PL1 (without VPSI), invasion of the elastic layer of the visceral pleura without reaching the visceral pleural surface, and PL2 (with VPSI), full invasion of the visceral pleura. Materials and Methods: Thirty-three patients with pathologically confirmed VPSI by NSCLC were retrospectively reviewed. Multidetector CT and contrast-enhanced 3T MRI with a free-breathing radial three-dimensional fat-suppressed volumetric interpolated breath-hold examination (VIBE) pulse sequence were compared in terms of the length of contact, angle of mass margin, and arch distance-to-maximum tumor diameter ratio. Supplemental evaluation of the tumor-pleura interface (smooth versus irregular) could only be performed with MRI (not discernible on CT). Results: At the tumor-pleura interface, radial VIBE MRI revealed a smooth margin in 20 of 21 patients without VPSI and an irregular margin in 10 of 12 patients with VPSI, yielding an accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and F-score for VPSI detection of 91%, 83%, 95%, 91%, 91%, and 87%, respectively. The McNemar test and receiver operating characteristics curve analysis revealed no significant differences between the diagnostic accuracies of CT and MRI for evaluating the contact length, angle of mass margin, or arch distance-to-maximum tumor diameter ratio as predictors of VPSI. Conclusion: The diagnostic performance of contrast-enhanced radial T1-weighted gradient-echo 3T MRI and CT were equal in terms of the contact length, angle of mass margin, and arch distance-to-maximum tumor diameter ratio. The advantage of MRI is its clear depiction of the tumor-pleura interface margin, facilitating VPSI detection.
In order to study the effect of sawdustboard combined with plastic chips, 0.5mm($T_1$), 1mm($T_2$), 1.4mm($T_3$) thick nylon fiber. polypropylene rope fiber(RP), and 0.23mm thick moth-proof polypropylene net fiber(NP) were cut into 0.5, 1, 2cm long plastic chips. Thereafter, sawdustboard combined with plastic chips prepared as the above and plastic non-combined sawdustboard(control) were manufactured into 3 types of one-, two-, and three layer with 5 or 10% combination level. By the discussions and results at this study, the significant conclusions of mechanical and physical properties were summarized as follows: 1. The MORs were shown in the order of 3 layer> 2 layer> 1 layer among plastic non-combined boards, and $T_3$ < $T_2$ < $T_1$ < RP (NP(5%) < NP(l0%) among plastic combined boards. In 2cm long plastic chip in 1 layer board, the highest strength through all the composition was recognized. 1 layer board showing the lower strength with 0.5cm plastic chip rendered to the bending strength improvement by 2 or 3 layer board composition. On the other hand, 2 or 3 layer combined with 1, 2cm long polypropylene net fiber chips incurred MOR's conspicuous decrease requiring optimum plastic chip combined level and consideration to combined type. 2. MOE in plastic non-combined 3 layer board exhibited sandwich construction effect by higher resin content application to surface layer in the order of 3layer>1layer>2layer with the highest stiffness of the board combined with polypropylene chip, while nylon chip-combined board had little difference from plastic non-combined board. In relevant to length and layer effect, 3 layer board combined with the 0.5cm long polypropylene net fiber chip in 5% and 10% combined level presented 34-43% and 44-76% stiffness increase against plastic non-combined board(control), respectively. Moreover, in 1 layer board, 30% stiffness increase with 10% against 5% combined level in the 1 and 2cm long polypropylene net fiber chip was obtained. 3. Stress at proportional limit(Spl) showing the fiber relationship (r: 0.81-0.97) between MOR presented in the order of 1 layer<2 layer<3 layer in plastic non-combined board. Correspondingly, combined effect by layer and plastic chip length was similar to MOR's. 4. Differently from previous properties(MOR, MOE, Spl). work to maximum load(Wml) of 2 layer board approached to that of 3 layer board. Conforming the above phenomenon. 2 layer combined with 0.5cm long polypropylene net fiber chip kept the greater work than 1 layer. The polypropylene combined board superior to nylon -and plastic non - combined board seemed to have greater anti - failing capacity. 5. Internal bond strength(IB), in contrast to MOR's tendency. showed in the order of T1
In mice, supplementation of t10,c12 conjugated linoleic acid (CLA) increases liver mass and hepatic steatosis via increasing uptake of fatty acids released from adipose tissues. However, the effects of t10,c12 CLA on hepatic lipid synthesis and the associated mechanisms are largely unknown. Thus, we tested the hypothesis that gut microbiota-producing t10,c12 CLA would induce de novo lipogenesis and triglyceride (TG) synthesis in HepG2 cells, promoting lipid accumulation. It was found that treatment with t10,c12 CLA ($100{\mu}M$) for 72 h increased neutral lipid accumulation via enhanced incorporation of acetate, palmitate, oleate, and 2-deoxyglucose into TG. Furthermore, treatment with t10,c12 CLA led to increased mRNA expression and protein levels of lipogenic genes including SREBP1, ACC1, FASN, ELOVL6, GPAT1, and DGAT1, presenting potential mechanisms by which CLA may increase lipid deposition. Most strikingly, t10,c12 CLA treatment for 3 h increased phosphorylation of mTOR, S6K, and S6. Taken together, gut microbiota-producing t10,c12 CLA activates hepatic de novo lipogenesis and TG synthesis through activation of the mTOR/SREBP1 pathway, with consequent lipid accumulation in HepG2 cells.
Journal of The Korean Society of Integrative Medicine
/
v.3
no.2
/
pp.9-16
/
2015
Purpose: The purpose of this research was to ascertain the effect of Micro-current on a pain, balance, of knee joint in the patients with degenerative arthritis. Method: The 30 subjects who had micro-current in this research and randomly assigned into two group, an experiment group and a control group. micro-current was applied to 15 subject in the experiment group after general physical therapy. experiment group was applies general therapies and micro-current stimulation. The measurement were analyzed by using SPSS(V.20). In order to compare the post to the amount of pre-changes and post-changes of each group, the paired t-test was used. The difference between the experiment group and the control group was analyzed by using the analysis of convariance. Results: The results of this study were as follows; 1) In VAS measures, the pain point was significantly decreased in both the experimental and the control group. 2) Mc Gill Pain Questionnaire(MPQ), the pain point was significantly decreased in both the experimental and the control group. 3) TUG measures, the second was significantly decreased in both the experimental and the control group. 4) Weight distribution measures, the authority was significantly decreased in both the experimental and the control group. Conclusion: The micro-current is considered a degenerative knee arthritis that can be presented as an effective physical therapy intervention.
Purpose: This study was conducted to investigate the effects of foot reflexzone massage on state - anxiety and discomfort of ovarian cancer patients receiving chemotherapy. Method: A quasi experimental design with a non equivalent control group and non synchronized design was used. The experiment was conducted from October 1, 2003 to September 30, 2004. The subjects consisted of 40 patients admitted to C University Hospital. Twenty subjects were assigned to the experimental group and received foot reflexzone massage everyday for 3 days. The other 20 subjects were in the control group and received routine care. Foot reflexzone massage was done on both feet of the subjects for 30 minutes for 3 days using standard protocol. The 'State-Anxiety Inventory' developed by Spielberger was used to measure the degree of state-anxiety. Discomfort was assessed using the 'Symptom Distress Scale' of McCorkle and Young. Data was analyzed by a SAS program using t-test, Wilcoxon signed rank sum test and Wilcoxon rank sum test. Results: State-anxiety and discomfort of subjects receiving foot reflexzone massage were significantly lower than those of the control group. Conclusion: These findings indicate that foot reflexzone massage could be an effective nursing intervention for relieving state-anxiety and discomfort in ovarian cancer patients.
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