• Title/Summary/Keyword: MAT1A

Search Result 605, Processing Time 0.024 seconds

Studies on the Breeding of Cold Hardiness and Technique of Overwintering Cultivation in Citrus (감귤(柑橘)의 내한성(耐寒性) 품종육성(品種育成) 및 내한(耐寒) 재배기술(栽培技術)에 관(關)한 연구(硏究))

  • Kim, Chi-moon;Song, Ho-kyung;Kim, Chung-suk
    • Korean Journal of Agricultural Science
    • /
    • v.4 no.2
    • /
    • pp.126-140
    • /
    • 1977
  • Present studies were carried out for breeding cold resistant clones of Citrus, improving overwintering techniques of Citrus in Jeju island as well as other southern region, Result obtained were as follows 1. In the vinyl house covered with two sheets of straw mat, 12 indivuals were found as non-injury and 15 were slightly injured by leaf freeging test at $-9^{\circ}C$ for 2 hours treatment. 2. In the condition of vinyl house covered with straw mat and viny film mulching and heat-in by sun-light, the inside temperature of vinyl house were not lowered below $-3^{\circ}C$ and the ground temperatura in vinyl house keeps above $0^{\circ}C$ during winter though outdoor temperature were lower by $-15^{\circ}C$(Daejeon area). 3. The vinyl tunnel inside the vinyl house and vinyl film mulching on ground position showed greater effectiveness for preventing heat loss from house but there were no significant difference between the color of vinyl film covered the tunnel. 4. In the vertical distribution of maximum temperature in vinyl house, the upper space was slightly higher than the lower position at high temperature condition, while minimum temperature was distributed as higher as the middle position, ground surface and upper position in order at low temperature condition 5. In the horizontal distribution of temperature in vinyl house, ground and surface-temperature of north side was lower than the other sides, and citrus planted within 30cm from north side wall died by cold injury and in the other side near wall appeared slight symptom of cold injury. 6. The insulating trench ($30{\times}30{\times}30cm$) packed with straw bundle installed under north wall might be effective to prevent heat loss of ground temperature. 7. In cloudy and snowy day, the temperature difference between indoor and outdoor were less, and the indoor temperature were maintained highly during night due to the effect of prevention of heat loss. 8. The highest temperature in a day was observed at about P.M. 3 both inside and outside of vinyl house and the lowest temperature was observed at about A.M. 6. The difference between the highest and lowest temperature of indoor in a sunny day was $19^{\circ}C$, compared with $9^{\circ}C$ on a cloudy or snowy day in late November. Especially, lowering of temperature in a snowy day was so less that the curve of temperature change was comparatively constant, 9. If the effective methods of citrus cultivation in vinyl house with improved clone such as hardiness. semi-dwarf and spur type are applied, it might be possible to cultivate the citrus tree safely in Jeju island as well as other southern rejion and to magnity the cultivation of citrus tree.

  • PDF

Molecular analysis on the pharmacological actions of oriental medicines in stomach cancer cells (수종 한약제의 위암세포에 대한 항암작용 효능 검색 및 약리작용에 관한 분자생물학적 연구)

  • Kim, Jin-Seong;Lee, Ji-Whyang;Ryu, Bong-Ha;Park, Jae-Hoon;Ji, Sung-Gil;Yoo, Jin-Hwa
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
    • /
    • v.5 no.1
    • /
    • pp.47-60
    • /
    • 1999
  • Traditional oriental medicines have been used for treatment of various kinds of human cancers for long times and some of them proven to be effective clinically. However, the pharmacological actions and mechanisms related to cancer treatment are generally unknown. In an effort to clarify the action mechanisms of several oriental medicines used for cancer treatments, we planned this experimental procedures. We selected Cordyceps sinensis (冬蟲下草), Punellae Herba (夏枯草), Rehmanniae Radix (熟地黃), Paeoniae Radix (白芍藥), Oldenlandiae Herba (白花蛇舌草), Partulaceae Herba (馬齒? ), Scdopendra subspinipes mutilans (蜈蚣), Mylabris Phalerara (班蟄), Phellinus igniarius(桑黃), Ganodermae Lignum(靈芝) for evaluation, which have been used for patients of gastric cancers. The twenty grams of medicines were boiled in 100ml of water for 1 hour and filtered with $0.2\;{\mu}m$ pore-sized filter unit to remove insoluble particles. Initially we evaluated the effects oriental medicines on growth inhibition in stomach cancer cells. The gastric cancer cell line, AGS, was cultured in RPMI 1640 supplemented with l0% heat-inactivated fetal bovine serum and treated with $10{\mu}l$ oriental medicines per 1ml of medium up to 48 hours. The specimens were subjected to MTT assay for evaluation of growth inhibition. We found mat Mylabris phalerata (班蟄) markedly suppressed the growth of cancer cells as shown in results. Next, we checked the effects of oriental medicines on cancer on cell cycles and apptosis. Mylabrls phalerata (班蟄) inhibited cell cycle progression of cancer cells a compared with control cells and cells treated with other medicines. In addition, Mylabri phalerata (班蟄) induced apoptosis in 30-40% of stomch cancer cells within 24 hours. Other oriental medicines used for this experiments did not show apoptosis-inducing effects on cancer cells. Finally, we determined the expression levels of genes associated with cell cycle and apoptosis. The expressions of Bcl-2 and bcl-XL were downregulated by the treatment of Mylabris phalerata (班蟄). However, the expression levels of genes related to cell cycles were not altered significantly. In conclusion, we found that Mylabris phalerata (班蟄) has in vivo gowth-inhibiting and apptosis-inducing effects on stomach cancer cells. However, we think that at least animal experiments are necessay for evduations.

  • PDF

Fall Risk Assessment of the Elderly living in Nursing Home (노인요양시설 거주 노인의 낙상 위험요인 조사 연구)

  • Yang, Sun-Hee;Park, Young-Hae;Cho, Hae-Sook;Baek, Hee-Chong
    • Journal of Korean Academic Society of Home Health Care Nursing
    • /
    • v.12 no.2
    • /
    • pp.1-15
    • /
    • 2005
  • Purpose: This study was conducted to assess the fall risk factors. Method: The subjects were 87 persons who were older than 65 years living at 28 nursing home in Seoul and Gyunggi province. Subjects were interviewed using RAFS II for intrinsic factor and the environmental factor were assessed using a structured questionnaire from Oct. to Dec. in 2004. The data were analyzed by SPSS(ver. 12.0) programs, using descriptive statistics, $x^2$-test, and t-test. Result: The 37.9% of the subjects experienced the fall, and its average number is $1.94\pm1.75$. The Women's experience of the fall was higher than that of the men, but it was no significant difference with gender. There was no significant difference with the age and duration of living. The mean of the intrinsic risk factor was 13.38 in total score 39 points marks on the RAFS II scales. The intrinsic risk factor score of the fallen group 15.71 was significantly higher than the non-fallen group 12.10. The variables of recent fall experience(t=4.72, p=0.000) and urinary dysfunction(t=2.64, p=0.010) was significantly higher than the non-fallen group. The highest variable of the intrinsic factor was the age and the variables of drug intake, balance, chronic disease, recent fall experience, urinary dysfunction were followed in order. The mean of the environmental risk factor was 0.24 points. No significant differences were shown in environmental risk factor between the fallen and the non-fallen groups. To the fallen group, the place of entrance was the highest risky environmental factor. To see in area dimension, the floor surfaces was the highest risky environmental factor and equipment and illumination factor was the following risky elements in order. In the total score of environmental risk factors based on the ares, the fallen group was 0.26 and the non-fallen group was 0.24, but there were no significant differences between the groups. Conclusion: This results suggested that visual protection strategy, set up the safety device in the place of entrance and inner stairway, bathroom and nonskid mat in the nursing home would be contribute to the prevention of the fall for the elderly.

  • PDF

Applications of Surface Cover Materials for Reduction of Soil Erosion (토양유실 저감을 위한 지표피복재 적용)

  • Won, Chul-hee;Shin, Min-hwan;Choi, Yong-hun;Shin, Jae-young;Park, Woon-ji;Choi, Joong-dae
    • Journal of Korean Society on Water Environment
    • /
    • v.27 no.6
    • /
    • pp.848-854
    • /
    • 2011
  • The objective of this research was to experimentally test the effect of rice straw mats on the reduction of runoff, sediment and discharge under a laboratory scale with different rainfall intensity and slopes. We used the small runoff plots of $1m{\times}1m{\times}0.65m$ ($L{\times}W{\times}H$) in size were filled with loamy sand. Experimental treatments were bare (control), rice straw mats + PAM(SP), rice straw mats + PAM + sawdust(SPS) and rice straw mats + PAM + rice husks(SPR); slope of 10% or 20%; and rainfall intensity of 30 or 60 mm/hr. Runoff volume and coefficient from covered plots were significantly lower than those from control plots. Under the 30 mm/hr and 10% simulations, average runoff coefficient of covered plots decreased more than 92%. Under 60 mm/hr and 20% simulations, the ratios were between 39.8~58.1%. Under the condition of 30 mm/hr rainfall and 10% slope, sediment discharge from covered plots was practically zero. And at 20% plots, sediment reduction ratio was more than 95%. Under the condition of 60 mm/hr rainfall, sediment reduction ratio of 10 and 20% plots ranged between 86.3~95.3% and between 79.8~86.5%, respectively. The differences in initial runoff time, runoff and sediment discharge among different cover materials were not significant. Rainfall intensity showed higher impact on initial runoff time, runoff, and sediment discharge than slope. It was also shown that even if runoff reduction by surface cover were low, sediment discharge reduction could be very significant and contribute to improve the water quality of streams in sloping agricultural regions. It was concluded that the use of straw mat and PAM on sloping agricultural fields could reduce soil erosion and muddy runoff significantly and help improve the water quality and aquatic ecosystem in receiving waters.

The effects of music listening, autogenic training, and music-assisted autogenic training on the quality of life, relaxation responses, and daily living of migraine patients

  • Lee, Suyeon
    • Journal of Music and Human Behavior
    • /
    • v.2 no.1
    • /
    • pp.67-85
    • /
    • 2005
  • The purpose of this study was to investigate the effect of music listening, autogenic training, and music-assisted autogenic training on the quality of life, physiological and psychological relaxation responses, and daily living in a population of migraine patients. Forty migraine patients, ranging 20 to 60 years, were referred to the researcher by their physicians and participated in the study. A convenience control-group pretest-posttest design was employed. The participants were randomly assigned to one of four groups: music listening (ML), autogenic training (AT), music-assisted autogenic training (MAT), or a control group participants, with n = 10 participants per group. The participants in experimental groups received four 30-minute sessions with an assigned treatment, once a week during a 4-week experiment period. The participants in the control group continued their regular medical treatment as prescribed by the doctor without receiving any other relaxation treatment. However, they were still aware of the research and their responsibilities for the study. The Migraine Assessment (MIDAS) and Migraine-Specific Quality of Life (MSQOL) questionnaire were used to investigate a migraine patients' quality of life collected before and after the 4-week experiment for all subjects. The physiological and psychological relaxation responses of migraine patients were measured by relaxation levels and forehead temperature recorded before and after each treatment session for the participants in three treatment conditions. The effect of the relaxation treatments on daily living of migraine patients was examined through the frequency and intensity of migraine headaches, and the amount of medication taken for migraine headaches during the 4-week experiment as recorded in participants' diary for all participants. The results found significant differences from pre- to posttest on the MIDAS, MSQOL, and relaxation levels while no significant was found among the groups. The analysis of forehead temperature showed no significant difference from pre- to posttest and among the groups. A one-way ANOVA was performed on the frequency, intensity, and amount of medication taken for migraine headaches during the 4-week experiment period. While results yielded no significant difference among the groups, the data indicate that the participants in the three treatment groups reported fewer migraine headaches, lower degrees of headache intensity, and less medication taken for migraine headaches than participants in the control group. A conclusion drawn from this study is that music listening itself as a relaxation treatment, or as an adjunct to other relaxation techniques can be effective in the treatment of migraine headaches.

  • PDF

Effect of the Soft Soil Layer on the Vertical Response of a Structure Excited with the Vertical Component of Earthquakes (연약지반이 수직방향 지진하중을 받는 구조물의 수직방향 반응에 미치는 영향)

  • 김용석
    • Journal of the Earthquake Engineering Society of Korea
    • /
    • v.3 no.1
    • /
    • pp.113-122
    • /
    • 1999
  • The importance of the vertical response of a structure was well recognized after the Hyogoken-Nanbu earthquake of Japan. However, most of the seismic design codes does not specified the site sail profiles, and the sail and foundations conditions were mostly neglected in the vertical seismic analyses of a structure. In this paper, the effects of foundation size, sail layer depth under the foundation, foundation embedment and pile foundation on the vertical seismic response spectra for both surface and embedded mat foundation were studied to investigate the effects of the soft soil layer on the vertical response of a structure excited with the vertical components of Taft and El Centro earthquakes, considering the sail profile types of $S_A,S_C,S_E$ in UBC-97, the medium and large size foundations, the soil layer depth under the foundation of 30 and 60m, the foundation embedment of 0 and 15m, and the precast reinforced concrete bearing piles installed in the soft soil deposit. According to the study results, the foundation size has a little effect on the vertical seismic response, However, the soil layer depth under the foundation of 60m has to be considered for the vertical seismic analysis of a structure as for the horizontal one. The embedded pile foundations as well as the surface ones built on the soft soil layer amplified the vertical seismic response of a structure very much.

  • PDF

Experimental Study on Field Applicability of Tightened Coupler with Two-Way Threading (양방향 나사산 체결방식을 활용한 완전밀착형 커플러의 시공성 분석)

  • Park, U-Yeol;Hong, Seong-Wook;Yang, Jin-Kook;Ko, Suck-Hwa;An, Sung-Hoon
    • Journal of the Korea Institute of Building Construction
    • /
    • v.14 no.1
    • /
    • pp.87-93
    • /
    • 2014
  • A tightened coupler with two way-threading is suggested to overcome the previous one-way threaded coupler. The experiment and a mock-up test were conducted to analyze the constructability of the suggested coupler. The aim of the mock-up test was to assemble the suggested coupler in horizontal rebar of mat footing and vertical rebar of semi-fabricated column bars. The method using the suggested coupler in semi-fabricated column bars is developed by analyzing the problem of fabricated column bars using the one-way threaded coupler. The result of the mock-up test showed that the time required to assemble the suggested coupler in the horizontal bars is shorter than it is for the one-way threaded coupler. In addition, the method using the suggested coupler in semi-fabricated column bars has advantages such as lower working loads, supporting safe work and strongly tightening the rebar. From these results, it is revealed that the suggested coupler is adequate to use in rebar work in terms of cost, quality and time.

Analysis of Behavior on GCP Composite Ground Considering Loading and Foundation Conditions (하중 및 기초조건에 따른 GCP 복합지반의 거동분석)

  • Kim, Gyeong-Eop;Park, Kyung-Ho;Kim, Dae-Hyeon
    • Journal of the Korean Geosynthetics Society
    • /
    • v.17 no.1
    • /
    • pp.127-137
    • /
    • 2018
  • Gravel Compaction Pile (hereinafter referred to as GCP) is a ground improvement technique by packing crushed stones on fragile clay ground, pressing it, and forming stakes on the foundation. Although many researchers have analyzed stress behavior of GCP composite ground on domestic GCP technique using laboratory experiment and field experiment, analyses of stress behavior according to the difference of stiffness of mat foundation loaded on the upper foundation of GCP composite ground have not been done actively. Therefore, this study aimed to identify the stress concentration ratio in accordance with the difference of basis stiffness by interpreting figures. To perform this, replacement ratio was changed and modelled using ABAQUS, software for finite element analysis and analyzed the stress concentration ratio, amounts of settlement, and maximum amounts of horizontal displacement of composite ground in accordance with the difference of stiffness. An analysis showed that the stress concentration ratio of rigid foundation was highly assessed than unloading of flexible foundation in case of unloading, while amounts of settlement under flexible unloading condition were slightly higher than under rigid condition. This indicates that the characteristic of stress behavior on the different stiffness of upper foundation needs to be clarified. In addition, the maximum horizontal displacement was generated in a constant level regardless of the difference of stiffness.

Development and Utilization of KASP Markers for the Identification of Three Types of Ephedra Herbs (마황 3종 판별을 위한 KASP 마커 개발과 활용)

  • Boreum, Park;Sun Hee, Lee;Kyung-Moon, Han;Jin Woo, Hwang;Hyung il, Kim;Sun Young, Baek
    • Korean Journal of Pharmacognosy
    • /
    • v.53 no.4
    • /
    • pp.226-233
    • /
    • 2022
  • Ephedra herbs are defined as stem of Ephedra sinica , Ephedra intermedia and Ephedra equisetina in the Korean Pharmacopoeia. It is important to use pure herbs to derive the safety and efficacy of herbal medicine. However, the identification of these herbs by conventional taxonomic methods is difficult. Recently, many studies have applied these DNA barcoding for the identification of herbal medicinal species using standard DNA markers. In this study, we report a case study in which the identification of Ephedra species was done by DNA barcoding. For identification of Ephedra species, 17 samples were collected, and a reference DNA barcode library was developed using 6 markers (rbcL, matK, ITS2, ycf1, ycf3, and rpoC2). To develop KASP-SNP markers, we selected 4 markers (ycf1, ycf3, rpl2, and rbcL), which were able to distinguish three Ephedra species. In the result, the specific markers for each of the three Ephedra were clustered into FAM-positive section, whereas non-targeted plants were clustered either HEX-positive or negative section. Therefore, we have developed KASP assay that allow rapid and easy Ephedra species identification using three KASP markers.

Centrifuge Model Tests on Trafficability of Very Soft Ground Treated with Geotextile and Sand Mat (토목섬유와 모래로 처리된 초연약지반의 장비주행성에 대한 원심모형실험)

  • Jun, Sang-Hyun;Lee, Jong-Ho;Yoo, Nam-Jae
    • Journal of the Korean Geotechnical Society
    • /
    • v.26 no.3
    • /
    • pp.13-23
    • /
    • 2010
  • In this study, centrifuge model tests with 50 g gravitational condition were performed to evaluate the bearing capacity of very soft ground, improved by spreading geotextile and sand on the surface of ground, for the heavy machinery to be able to access. For undrained shear strength of ground model, prepared with the clay sampled from the field, being in the range of 3.1~11.7 kPa, bearing capacity tests were performed with the model footing and the loading system built to simulate the heavy machinery on the ground model treated with geotextile and sand. Test results were compared with theoretically and numerically evaluated ones. Test results about load-settlement curves showed that the bearing capacity increases with the increase of the undrained shear strength of ground. Punching shear or local shear failure was also observed. For a relatively low undrained shear strength of ground, settlement behavior is found to be crucial to evaluating the trafficability of machinery whereas bearing capacity becomes a dominant factor with the increase of undrained shear strength of ground. The method for assessing the bearing capacity of the ground related to trafficability of machinery is presented by acquiring the regression relationship between the contact pressure of machinery and settlements using load-settlement curves with the change of the undrained shear strength. Furthermore, results of numerical analyses about load-settlement relation are in relatively good agreement with those of centrifuge model test.