• Proceedings of the Korean Society for Rock Mechanics Conference
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• 2004.04a
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• pp.123-140
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• 2004

저준위 방사성폐기물 안전성 평가를 위해서 안전성 평가 대상에 관한 기술이 이해당사자들이 이해하기 명확하고 쉽게 설정되어야 한다. 방사선적 안전성 평가 시나리오란 처분장으로부터 유출된 방사성 물질들이 공학적 방벽과 천연 방벽을 거쳐 생태계로 어떻게 이동하는가에 대한 설명으로 안전성 평가를 위한 일종의 대본과 같은 역할을 한다. 본 논문에서는 핵종 이동 현상을 RES(Rock Engineering System) 방법론에 의거 기술하였다. 국내 처분장의 특성을 고려하여 처분 시설은 연안에 동굴 처분 방식으로 건설된다고 가정하여 생태계를 산정하고, 공학적 및 천연 방벽들이 처분장 설계 시 예상한 기능들을 수행한다고 가정하여, 기준 시나리오를 설정하였다. 또한 다양한 설계 고려 요소들을 고려하여 대안 시나리오들을 도출하고자 하였다. 도출된 시나리오의 주요 항목들을 평가하기 위해서 AMF(Assessment Method Flowchart)를 도출하였다. 주어진 지형 조건에 따라 확률론적 방사선적 안전성 평가를 위해 각 지층 구조별 이동 거리 및 시간을 CONNECTFLOW를 이용해 산정하고, 그 결과들을 Response surface method를 이용해 확률 밀도함수로 도출하여 방사선적 안전성 종합 평가 코드인 MASCOT-K의 입력 자료로 활용되도록 하였다.

• Food Science and Biotechnology
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• v.14 no.6
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• pp.854-859
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• 2005

Although action modes of equol and genistein have been extensively studied, their precise roles in tumor cells remain elusive. To address possible effects of these compounds on protein expression in mammary tumor cells, proteins modulated in MCF-7 mammary tumor cells when incubated in absence and presence of 10 uM equol or genistein were identified through 2-dimensional gel electrophoresis, MALDI-TOF MS/MS, and NCBInr database search using Mascot software. Most proteins differentially expressed in MCF-7 cells after treatment with 10 uM genistein or equol were identified as being the same. Exposure to both compounds caused decreased cellular expression of RNA-binding protein regulatory subunit and oncogene DJ1 tubulin beta-1 chain, and increased expression of heterogeneous ribonucleoproteins F and L, KH-type splicing regulatory protein, and translation elongation factor EF-Tu precursor. Genistein and equol at dose used in this study showed common action mechanism.

• BMB Reports
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• v.41 no.7
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• pp.516-522
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• 2008

The glycation of BSA leads to protein/peptide modifications that result in the formation of AGEs. AGEs react with the amino groups of N-terminal amino acid residues, particularly arginine and lysine residues. Enhanced AGE formation exists in the blood and tissues of diabetics, as well as in aging and other disorders. The Identification of AGEs is of great importance. Mass spectrometry has been applied to identify and structurally elucidate AGEs. Here, we report on the identification of AGE-peptides and AGE precursors based on relative mass changes as a result of specific AGE formation. HPLC-ESIMS, ESI-MS/MS, and the Mascot database were used. The relative mass changes due to the specific type of AGE formation were added to the identified peptides followed by a manual search of the glycated samples, which resulted in the identification of seven peptides for the formation of five AGEs, namely CML, pyrraline, imidazolone A, imidazolone B, and AFGP. Four glycated peptides (FPK, ECCDKPLLEK, IETMR, and HLVDEPQNLIK) were identified in the formation of AGE-precursors.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2007.11a
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• pp.714-717
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• 2007

This paper presents the findings that may be useful for establishing safety policies involved with safety plan, program, and control relative to fatal accidents in construction job site. The fatal accident investigation database maintained by Korean Production Household Mascot Safety Industrial Complex is accessed. The 5 years fatal accidents occurred in 2002 to 2006 were analyzed. The statistic relative to the fatal accidents in different project types is obtained using different classifications such as occupation, years of experience, accident type, and time in a day. This research would contribute to ensure the effectiveness of safety policy so as to enhance worker safety.

• Journal of the Korean School Mathematics Society
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• v.9 no.4
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• pp.539-556
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• 2006

Tessellations are the pattern of iterations of geometric transformation. We can find them in the works of Escher, the famous Dutch artist. Also, We can find the beauty of tessellations in traditional Korean house doors, old Korean architecture, palace walls, and so forth. In this article, the figures of patterns we present are a pig, a frog, Tchiucheonwhang (the mascot of Korean football supporters), and figures by Escher, using the computer geometric program, GSP (Geometer's Sketchpad). We wanted to investigate the gender differences on students' achievement and disposition toward mathematics in constructing tessellations. The results indicated that if students were supported with well prepared instructional materials which helped students make their own figures, female students in particular would be more interested in learning geometric transformation.

• Journal of Digital Contents Society
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• v.19 no.6
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• pp.1061-1068
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• 2018

Design is already an integral part of our lives and is in many different forms. Creating a variety of designs has made it more important to establish the value of the design, and maintaining consistency through correct use and distribution of the developed design as important as development. The 2018 Pyeongchang Winter Olympic Games and the Winter Paralympics, which were held at the groval level, played an important role in creating and operating diverse contents to promote Korea to the world. He created emblems with the motif of " Hangul, " which can reflect Korean characteristics, and a mascot that reveals the identity of the competition. The generated contents were created as design guides for the convenience of users (sponsors, media, relevant agencies, etc.) and managed through the Design Distribution System (DDS). The researcher wants to determine the effectiveness and value of the design distribution and management system based on the results obtained by operating the DDS of POCOG.

• Proceedings of the Korea Society of Poultry Science Conference
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• 2004.11a
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• pp.37-38
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• 2004

Salmonella gallinarum is a pathogen that is capable of causing disease in Korean native chicken. Although Salmonella gallinarum is important world-wide pathogens of poultry, little is understood of the mechanisms of pathogenesis of Salmonella gallinarum in the chicken. This study was to investigate chicken liver proteins affected by infection of Salmonella gallinarum in Korean native chicken. The differentially expressed proteins of chicken livers were identified by using 2-dimensional electro- phoresis (2D-E) and mass spectrometry (MS). We detected more than 300 protein spots on silver stained 2D gels using pH 3∼10 gradients. Three differentially expressed protein spots were analyzed by MALDI-TOF MS and MS/MS. The obtained MS and MS/MS data were searched against a protein database using the Mascot search engine. Further researches on the identified proteins can give valuable information of mechanism of pathogenesis in chicken.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.5
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• pp.638-644
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• 2007

Differences of meat qualities between Japanese Black and Holstein have been known in Japan, however, the causative proteins and/or the genetic background have been unclear. The aim of this study was to identify candidate proteins causing differences of the meat qualities between the two breeds. Using technique of two-dimensional gel electrophoresis, protein profiling was compared from samples of the longissimus dorsi muscle and subcutaneous adipose tissue. Five protein spots were observed with different expression levels between breeds. By using LC-MS/MS analysis and Mascot program, three of them were identified as ankyrin repeat protein 2, phosphoylated myosin light chain 2 and mimecan protein. Subsequently, we compared the DNA coding sequences of three proteins between breeds to find any nucleotide substitution. However, there was no notable mutation which could affect pI or molecular mass of the proteins. The identified proteins may be responsible for different characteristics of the meat qualities between Japanese Black and Holstein cattle.

• Journal of the Korean Institute of Landscape Architecture
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• v.30 no.2
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• pp.79-87
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• 2002

This landscape design proposal was presented to a design competition for the KangWon Province Police Agency(KPA). The site, about 27,711 $m^2$, is located at 293-4 Udu-dong, Chunchun, KangWon-Do. Design objectives of the KPA were to build a symbolic place which fall community members with pride, to elevate an identity and status of the KPA by creating a landscape correspondent to the concept of the building design, to provide community residents with a space to enjoy cultural and social activities, and to make environment friendly space. The main concept was developed by one of characteristics of the traditional spatial structure of Korea known as an, 'Open and Closed spatial structure.'By re-interpreting the traditional spatial structure and applying it to the site, the design met the various desires of the KPA. The site is primarily segmented into 6 sub spaces; entrance space Podori plaza, symbolic court, police billeting area, sports area, and rear rest area. The entrance space, Podori plaza, and symbolic court on the south-west part of the site represent the publicity of the site as the concept of ″open space.″ On the contrary, considering the specialty of police affairs, the north-east part of the site, which contains the police billeting area and rest area, were designed to maintain security by using the concept of ″closed space.″ To express an identity of the KPA, 'Podori', a police mascot, the plaza was designed and is suppose to function as the hub of the community. In the front section of the plaza, a symmetrical planting pattern, centering the strong axis, was introduced to strengthen its symbolic meaning. Traditional window frames such as the pattern of 'Pisal-jige'and 'Umulsal-jige' were used for the paving system which is applied as the environment friendly design. Site facilities and furnitrue were placed at every important spot in order to connect various spaces organically. As these well-tied spaces properly shared their function, spatial sequence and management would be promoted. The entire space was designed to allow free access of handicapped people. This proposal is meant to create a new image of KangWon province and to enhance the way of inhabitants' think about their community.

• Journal of Digital Contents Society
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• v.18 no.1
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• pp.47-54
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• 2017

In this research, I analyze cases of character packages in Japane, extract the concept of design that was loved by consumers and inmates and succeeded in marketing, and aim to establish the logic and principle. In addition, in the future, when introducing and utilizing the character package design in Korea, this research intends to make a guideline for the development of objective validity and empathic package design. After identifying the design concept and finding the principle by targeting package design of five character of Tohato which mixed various media and expanded sales, I want to find out the cause of success. Therefore, I have studied the theory and principles of enterprise and creative in product strategy through case analysis of character design concept and character package design. As a result, a design that leaving the functional side, having a story, making memories, and inducing a sense of closeness was as a successful case of renewal. In the package design, in some cases, package design execution is more important under the theoretical system according to consumer behavior analysis and Promotion of bold design concept of the design for the success of that concept, deviated from the existing principle.