• FOCUS: LIFE SCIENCE
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• 제1호
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• pp.8.1-8.3
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• 2024

Ultra-high performance liquid chromatography (UHPLC) systems are integral to modern analytical laboratories, necessitating careful maintenance and operation protocols to ensure optimal performance. This document provides comprehensive guidelines for the proper shutdown and reactivation of UHPLC systems to prevent damage and maintain operational efficiency. • Shutdown: Remove the column and replace it with a union to avoid blockages. Flush the system with a compatible solvent mix, clean mobile phase reservoirs to prevent microbial growth, flush the pump with storage solvent, and clean the autosampler, including the needle and injection port. • Reactivation: Inspect the system for wear or damage, gradually reintroduce mobile phases starting with a weak solvent, reinstall the column securely, and perform system checks on baseline stability, pressure consistency, and detector performance. By adhering to these guidelines, laboratories can ensure the longevity and reliability of their UHPLC systems, maintaining high analytical performance and minimizing downtime. These procedures help prevent common issues such as blockages, contamination, and component wear, thereby supporting efficient and accurate analytical operations.

• Journal of Magnetics
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• 제21권3호
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• pp.425-430
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• 2016

The aim of this study was to measure the setup variation for X (lateral), Y (longitude), and Z (vertical) by taking magnetic megavoltage computed tomography (MVCT) before treating the brain, oropharynx, lung, and prostate patients on helical tomotherapy. In this study, 30 patients were chosen for each of the treatment areas, and their skin was labeled with a mark on a treatment planning reference point when taking CT. We preceded MVCT prior to tomotherapy and then conducted an auto registration based on the bony landmarks; image registration was used for automatically matching the patient's setup. Lastly, we confirmed and evaluated the translation coordinates of the images for 30 patients. The following shows the comparison result of the setup errors of each part: X (lateral) showed the highest setup errors with $3.44{\pm}2.05$ from Lung; Y (longitude) showed the highest setup errors showing $3.40{\pm}2.87mm$ from Prostate; and Z (vertical) showed the highest setup errors showing $6.62{\pm}4.38mm$ from Lung. This result verifies that the setup error can be prevented by taking MVCT before the treatment, and Planning Target Volume (PTV) margins can be reduced by referring to the resulting value of each treatment part. Ultimately, the dosage of the normal organs can be decreased as well as any side effects.

• 한국치위생학회지
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• 제15권6호
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• pp.1027-1032
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• 2015

Objectives: The purpose of the study is to investigate the attitude toward medical health information in the dental hygiene students. Methods: The subjects were 370 dental hygiene college students in the metropolitan area. A self-reported questionnaire was completed by 350 students from March 2 to May, 3, 2014. Except 20 incomplete answers, data were analyzed by frequency analysis, t-test, and one-way ANOVA using SPSS 12.0 program. The questionnaire consisted of general characteristics of the subjects, satisfaction of internet use, and attitude toward medical health information. Results: Most of the students had personal computers and they did not receive computer education. The students used internet in the variety of the fields. Satisfaction level was 3.28 by 5 point Likert scale. The attitude toward medical health information was 3.20. They would not use computer if possible, and the score was 3.50 points that was the highest mark. There was no statistically significant difference in medical health information by the general characteristics of the subjects. Conclusions: The attitude toward medical health information was not fully satisfactory in many fields. The curriculum for the dental hygiene must include step-by-step computer course and the computer education must provide the diverse educational opportunities for the students.

• 약학회지
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• 제32권1호
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• pp.86-94
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• 1988

Some rheological properties of subfractions for dextran in the molecular weights range from $3{\times}10^4$ to $2{\times}10^6$ was investigated at room temperature. The dependence of the viscosity on concentration, shear rate, pH & ionic strength, temperature and solvent effect was observed. From the experimental data the Mark-Houwink viscosity equation in water at $25^{\circ}C$ was determined for samples having the molecular weight ranging from $3{\times}10^4$ to $2{\times}10^6$ as$[{\eta}]=3.1{\times}10^{-3}\;Mw^{0.39}(in\;dl/g)$. The intrinsic stiffness of the dextran backbone was estimated by evaluating the 'characteristic ratio' $C_{\infty}$, which is below the 0.082. In the concentrated region, the viscosity was decreased with increasing shear rate and was exponentially decreased with raising temperature, the viscosity showed the maximum value at neutral condition. From the experimental data, it was concluded that dextran chain, linked by the ${\alpha}-1$, 6-glucosidic linkage, behaves like a flexible random coil chain in aqueous solution, dextran solutions were pseudoplastic power law fluids among the empirical models of non-Newtonian behavior. Urea was an active reagent which increases the viscosity and swells dextran while pyrididine and glycerol were inactive reagents. Also, it could be estimated that the formation of gel structure is promote to the neutral state, the molecular weight larger than $2{\times}10^5$, when electrolytic concentration is IN and Ureas is use to solvent.

• 항공우주기술
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• 제12권1호
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• pp.128-136
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• 2013

최근 자율 비행에 대한 관심이 증가하면서 다양한 센서를 통한 자기 위치 인식 연구가 진행되고 있다. 특히 GPS와 같은 자기 위치를 확보할 수 없는 실내 환경의 경우, 다른 방법을 통해 자기 위치를 파악해야 한다. 실내 환경에서 자기 위치 파악에는 여러 가지 방법이 있지만 영상을 통한 위치 인식 기술이 각광을 받고 있다. 본 논문에서는 마크를 통한 영상 기반의 위치 인식 연구에 대해 설명하고, 실제 비행체에 적용하여 자율 비행하는 방법에 대해 제안한다. 그리고 마크가 없는 실제 환경에서도 위치를 인식할 수 있도록 실시간 3차원 지도 생성을 통한 위치 인식 방법에 대해서도 논의한다.

• 한국유체기계학회 논문집
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• 제18권1호
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• pp.20-28
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• 2015

The pump-turbine impeller is the key component of pumped storage power plant. Current design methods of pump-turbine impeller are private and protected from public viewing. Generally, the design proceeds in two steps: the initial hydraulic design and optimization design to achieve a balanced performance between pump mode and turbine mode. In this study, the 3D inverse design method is used for the initial hydraulic impeller design. However, due to the special demand of high performance in both pump and reverse mode, the design method is insufficient. This study is carried out by modifying the geometrical parameters of the blade which have great influence and need special consideration in obtaining the high performance on the both modes, such as blade shape type at low pressure side (inlet of pump mode, outlet of turbine mode) and the blade lean at blade high pressure side (outlet of pump mode, inlet of turbine mode). The influence of the geometrical parameters on the performance characteristic is evaluated by CFD analysis which presents the efficiency and internal flow results. After these investigations of the geometrical parameters, the criteria of designing pump-turbine impeller blade low and high sides shape is achieved.

• Journal of Communications and Networks
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• 제11권3호
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• pp.287-296
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• 2009

Although asymptotic bounds of wireless network capacity have been heavily pursued, the answers to the following questions are still critical for network planning, protocol and architecture design: Given a three-dimensional (3D) network space with the number of active users randomly located in the space and using the wireless communication technology, what are the expected per-flow throughput, network capacity, and network transport capacity? In addition, how can the protocol parameters be tuned to enhance network performance? In this paper, we focus on the ultra wideband (UWB) based wireless personal area networks (WPANs) and provide answers to these questions, considering the salient features of UWB communications, i.e., low transmission/interference power level, accurate ranging capability, etc. Specifically, we demonstrate how to explore the spatial multiplexing gain of UWB networks by allowing appropriate concurrent transmissions. Given 3D space and the number of active users, we derive the expected number of concurrent transmissions, network capacity and transport capacity of the UWB network. The results reveal the main factors affecting network (transport) capacity, and how to determine the best protocol parameters, e.g., exclusive region size, in order to maximize the capacity. Extensive simulation results are given to validate the analytical results.

• 대한치매학회지
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• 제17권3호
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• pp.120-129
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• 2018

Background and Purpose: Prospective memory (PM) has a known relationship with frontal function, and PM decline has been observed in amnestic mild cognitive impairment (aMCI). Cerebral small vessel disease, as evidenced by white matter hyperintensities (WMHs), is linked to frontal dysfunction. This study was undertaken to evaluate the relationship between PM decline and WMHs in patients with aMCI. Methods: Of 74 enrollees with aMCI, 69 completed this prospective study. We compared total scores and sub-scores of the Prospective and Retrospective Memory Questionnaire (PRMQ) administered at baseline and 3 months later, stratifying patients by degree of WMHs. Results: A significant decline was seen in PRMQ total scores and PM scores at the 3-month mark in patients with moderate (vs. mild) degrees of WMHs ($-2.8{\pm}7.2$ vs. $0.2{\pm}7.1$; p=0.032). In addition, patients with moderate (vs. mild) degrees of deep WMHs (DWMHs) showed greater PM decline, whereas PM loss in patients with mild, moderate, or severe degrees of periventricular WMHs (PVWMHs) did not differ significantly. Conclusions: Findings of this study indicate that the burden of WMHs is consistently implicated in PM deterioration experienced by patients with aMCI, and signifies greater PM decline, especially in instances of extensive DWMHs. Greater attention to the change of PM is therefore needed in aMCI patients with WMHs.

• 한국해양학회지
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• 제5권1호
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• pp.37-40
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• 1970

삼치, Scomberomorus niphonius (Cuvier et Valenciennes), 는 우리나라 수출전략어종중 가장 중요한 위치를 차지하고 있는 어종의 하나이며 1968년도 삼치총어획고는 7,590 M/T으로서 7억1천4백여만원선에 달하였으며 이중 거의 전량이 수출되고 있다. 이와같이 경제적 위치가 높은 어종인데도 불구하고 삼치자원에 대한 조사연구보고는 전혀 없어 이 자원에 대한 조사연구가 절실히 요망되어 왔었다. 필자는 자원해석을 행함에 있어서 무엇보다 기분적인 지견이 되는 성장과 년령과의 관계를 구명하기 위한 제1차 조사작업으로 삼치의 년령사정법에 관한 문제를 취급하였다. 1969년에 발생한 서남해안 일대의 코레라 사태와 제한된 연구기간등으로 인한 계절적 자료의 부족으로 상기목적에 적합한 표분을 계통적으로 수집하기 못해 완전한 검토는 못하였지만 일부 1969년도 자료를 분석한 결과 춘추골로서 년령사정이 가능하다는 것을 알게 되어 이에 그 개요를 보고한다.

• 융합신호처리학회논문지
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• 제12권4호
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• pp.333-340
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• 2011

한국천문연구원은 한일상관센터 (Korea-Japan Correlation Center, KJCC)에 2009년부터 한일공동VLBI상관기(Korea-Japan Joint VLBI Correlator, KJJVC)를 설치하여 운영하고 있다. 한일공동VLBI상관기는 한국우주전파관측망(Korean VLBI Network, KVN), VERA(VLBI Exploration of Radio Astrometry), JVN(Japanese VLBI Network) 및 공동 관측망 등에서 관측한 VLBI(Very Long Baseline Interferometer) 데이터를 상관처리하고, 과학적 목적을 위해 관측데이터를 처리하는 전용 계산기로 사용된다. KJJVC는 각 구성시스템 사이의 데이터 입출력 규격으로 VLBI 국제표준인 VSI(VLBI Standard Interface)를 따르고 있다. 특히 관측된 데이터를 상관처리하기 위해 고속재생기인 Mark5B시스템과 동기재생처리장치(Raw VLBI Data Buffer, RVDB) 사이에는 1024 Mbps급으로 데이터가 전송된다. 고속 데이터 전송에 있어 발생하는 전자기 방해 (Electromagnetic Interference, EMI)는 관측데이터의 손실을 야기 시키며, 전송 케이블의 길이가 길수록 손실 발생빈도가 많고, 디지털 데이터 신호의 전압레벨을 감소시켜 데이터 인식 오류를 초래한다. 따라서 본 논문에서는 VSI 규격의 통신에서 발생하는 EMI 잡음 정도를 측정하고, 데이터 손실을 최소화할 수 있는 방법으로 1) RC 필터를 사용한 방법, 2) Microstrip 라인을 이용한 임피던스 매칭, 3) Differential line driver를 이용한 신호 복원 방법 등을 제안하였다. 각 제안방법들의 유효성을 확인하기 위해 제안방법들은 시뮬레이션과 실험적인 구현을 통하여 성능시험을 수행하였으며, 각각의 제안 방법이 VSI 규격의 고속 데이터 전송에 유효함을 확인하였다.