• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2021년도 학술발표회
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• pp.350-350
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• 2021

한국건설기술연구원의 돌발홍수연구센터는 돌발홍수예측 시스템을 구축하여 2019년부터 전국에서의 돌발홍수정보를 제공하고 있다. 2019년에는 초단기 예측 모델인 Macgill Algorithm for Precipitation-nowcast by Lagrangian Extrapolation(MAPLE) 알고리즘으로부터 생산된 초단기 예측 강우를 활용하여 동(읍/면) 단위로 1시간 선행 예보를 제공하였다. 2020년에는 추가로 초단기 예측 강우와 수치예보 자료를 병합한 예측 병합 강우 자료를 생산하여 예측 선행시간을 1시간에서 3시간까지 확장하였다. 돌발홍수예측 시스템의 목표는 도시 및 산지소하천에서의 돌발홍수에 대응하기 위한 정보를 실시간으로 사용자에게 제공하여 수재해에 빠르게 대응하는 것이다. 이에 돌발홍수예측 시스템은 2019년부터 실시간으로 운영하여 홍수기에 보다 빠른 돌발홍수정보를 제공해왔다. 본 연구에서는 2020년 우기에 운영된 돌발홍수시스템에 대한 평가를 수행하였다. 이를 위해 부산(07.23), 대전(07.29), 서울(08.01), 경기-충북(08.02)에서 발생한 수재해 사례를 분석하였다.

• 한국음향학회지
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• 제23권4호
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• pp.288-295
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• 2004

천해는 속도가 빠르고 강한 간섭표적으로 인하여 신호단편 (snapshot) 수가 제한되어 인접한 느리고 약한 표적을 탐지하기 어려운 환경이다. 천해환경에서 적응정합장처리에 적용하여 고소음의 간섭표적의 효과를 줄일 수 있는 도파관 공간의 간섭표적 필터링 기법을 제안하였다. 이를 위하여 NDC (null direction constraint)를 적용한 MCM (multiple constraint method) 기법을 새로운 공간간섭 필터로 제안하였다. NDC는 복제음장을 이용하여 CSDM (cross-spectral density matrix)에 포함되어있는 강한 소음원 성분을 강제적으로 걸러줌으로서, 부엽 준위가 낮아지고 저소음표적 신호의 이득을 복원시킨다. 이 기법을 Pekeris 도파관에서의 시뮬레이션 및 동해에서 수행한 정합장처리 실험인 HAPLE03 (matched acoustic properties and localization experiment)의 수직선배열 자료에 적용하였으며, 그 결과 인접한 저소음 표적의 SBNR (signal-to-background-and-noise ratio)이 MVDR (minimum variance distortionless response)과 NSP (null space projection) 보다 향상되었다.

• 박물관보존과학
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• 제5권
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• pp.31-36
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• 2004

본 실험은 현재 박물관에서 사용하고 있거나 사용 검토 중이던 목재수종 6종(물푸레나무, 삼나무, 흑호두나무, 솔송나무, 오동나무, 단풍나무)을 대상으로 금속부식 영향을 조사한 것이다. 부식 테스트의 방법으로는 실험하고자 하는 재료와 test 시편(금속시편)을 일정 온습도에서 장시간 노출시키면서 재료가 시편에 미치는 영향을 관찰하는 Oddy test를 사용하였다. 6종의 나무 자재를 대상으로 실시한 Oddy test 결과 수종에 따라 금속부식의 형태가 조금씩 다르게 나타났으며, blank를 제외한 대부분의 철(Fe)과 납(Pb)시편에서는 표면전체에 부식이 발생하였다. 또한 구리(Cu)시편에서도 정도는 다르지만 모든 시편에서 조금씩 변색이 된 것을 관찰할 수 있었다.

• 한국산학기술학회논문지
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• 제15권11호
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• pp.6739-6745
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• 2014

은행속에 속하는 산청목은 중국과 한국 북동부지역에 널리 분포하는 자생 식물로 전통적으로 항염증제로 사용되었으며 현재까지 항우울에 대한 효능과 그에 대한 면역변화에 대한 연구는 미흡한 실정이다. 본 연구실에서는 100, 200, 그리고 400 mg/kg 농도의 산청목추출물을 실험쥐에게 경구투여를 실행하였으며 강제수영실험을 통하여 항우울효과를 평가 그리고 혈 중 코티솔, ACTH, 그리고 사이토카인의 농도를 측정하였다. 실험 결과 실험쥐에 경구투여한 산청목 투입량이 증가함에 따라 강제수영실험에서의 행동불능시간이 감소하였으며 수중공포에 의해 분비유도된 사이토카인 농도 또한 감소함을 볼 수 있었다. 특히 코티솔, IL-6 과 $IL-1{\beta}$농도가 산청목 투입군에서 유의하게 감소함을 알 수 있었다. 산청목 경구투여군에서의 부동시간의 감소와 전염증성 사이토카인의 저하를 종합하여 볼 때 산청목의 항염증 효능으로 인한 작용에 의하여 강제수영 실험에서 항우울효과가 발현했다고 간주된다.

• Clinical and Experimental Pediatrics
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• 제55권9호
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• pp.322-329
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• 2012

Purpose: Aeroallergens are important causative factors of allergic diseases. Previous studies on aeroallergen sensitization rates investigated patients groups that had visited pediatric allergy clinics. In contrast, we investigated sensitization rates in a general population group of elementary school to teenage students in Incheon, Jeju, and Ulsan. Methods: After obtaining parental consent, skin-prick tests were performed on 5,094 students between March and June 2010. Elementary school students were tested for 18 common aeroallergens, whereas middle and high school students were tested for 25 allergens. The 25 allergens included Dermatophagoides pteronyssinus, Dermatophagoides farinae, pollen (birch, alder, oak, Japanese cedar, pine, willow, elm, maple, Bermuda grass, timothy grass, rye grass, orchard grass, meadow grass, vernal grass, mugwort, Japanese hop, fat hen, ragweed, and plantain), and mold (Penicillatum, Aspergillus, Cladosporium, and Alternaria). Results: The sensitization rates in descending order were 25.79% (D. pteronyssinus ), 18.66% (D. farinae ), 6.20% (mugwort), and 4.07% (willow) in Incheon; 33.35% (D. pteronyssinus ), 24.78% (D. farinae), 15.36% (Japanese cedar), and 7.33% (Alternaria) in Jeju; and 32.79% (D. pteronyssinus), 30.27% (D. farinae), 10.13% (alder), and 8.68% (birch) in Ulsan. The dust mite allergen showed the highest sensitization rate among the 3 regions. The sensitization rate of tree pollen was the highest in Ulsan, whereas that of Alternaria was the highest in Jeju. The ragweed sensitization rates were 0.99% in Incheon, 1.07% in Jeju, and 0.81% in Ulsan. Conclusion: The differences in sensitization rates were because of different regional environmental conditions and distinct surrounding biological species. Hence, subsequent nationwide studies are required.

• 보험의학회지
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• 제18권
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• pp.107-110
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• 1999

The disorders of congenital metabolic errors causing mental retardation can be prevented by early diagnosis and treatment. We analysed 144,000 neonatal blood samples for phenyketonuria(PKU), maple syrup urine disease(MSUD), homocystinuria(HCU) and histidinuria(HE) by bacterial inhibition method, and galactosemia(GAL) by Paigen method. In our survey, the positive were 4 samples in PKU(4mg/dl;2, 6mg/dl;1, 8mg/dl;1), 8 samples in MSUD(4mg/dl;2, 6mg/dl;2, 8mg/dl;3, 10mg/dl;1), 4 samples in HCU(4mg/dl;2, 6mg/dl;2), 4 samples in Galactosemia(4mg/dl;2, 6mg/dl;1, 8mg/dl;1), respectively. while, no one was positive in HE. The frequncy rate were 1/36,000 for PKU, HCU and GAL, 1/18,000 for MSUD, respectively. But those for HE couldn't be detected in our survey. In this study, the hightest frequency rate was 1/18,000 of MSUD, following were 1/36,000 for PKU, HCU and GAL, respectively. As results our data, it is our opinion that neonatal screening should be performed in terms of national policies for ealy diagnosis and theraphy.

• 대한한의학원전학회지
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• 제29권2호
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• pp.31-54
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• 2016

Objectives : The goal of this paper is to research what affected diagrams of liver originated from Mingtangzangfutu while they were changed. Methods : Diagrams of liver in Traditional Chinese and Japanese medical books had been gathered as many as possible. After they were divided into ones which were originated from Mingtangzangfutu and the others, diagrams originated from Mingtangzangfutu, were again classified into 4 filiations according to Huang Longxiang(黃龍祥)'s standard. Apart from his classification, they were analysed by 4 form factors, e.g. shape, number, veins and petiole of leafs. Results : Reliability of this methods had been confirmed by the correspondence with Huang's 14 standard books, before 29 diagrams of liver were derived from 33 books including 13 books that Huang had already suggested. The lobes of liver in most of diagrams resembled 7 lanceolate or long oval leafs, or a maple leaf with 6 indentations, 4 left lobes and right 3 ones. In most of diagrams, veins of leafs were described variously, and petioles of leafs were drawn more shortly or longer. Analysing 29 diagrams by 4 form factors proved that Huang's classification had crossing features among 4 filiations. This phenomenon implied the painters or doctors drawing diagrams might not convince if the shape of liver was correct or not. Although veins and petiole of leafs in diagrams of liver could be compared with tissues in liver in modern human anatomy, diagrams were not been affected by dissection from Yuan(元) to middle Qing(淸) dynasty. Conclusions : Lingshu(靈樞), Nanjing(難經) and Wang Bing would had constantly acted on 29 diagrams of liver, since diagram of liver originated from Mingtangzangfutu, appeared first in Zhenjiujuying(鍼灸聚英). But they did not come from dissection during same periods.

• 박물관보존과학
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• 제20권
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• pp.93-106
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• 2018

국내 악기 박물관에 전시되어 있는 악기는 목재, 석재, 금속, 가죽, 흙 등 다양한 재질로 구성되어 있다. 그 중 유기재료로 제작된 악기는 시간 경과에 따라 물리적·화학적·생물학적인 손상이 발생한다. 이러한 악기를 보존·복원하는 경우, 소리를 내는 악기라는 특성상 악기재료의 연구뿐만 아니라 제작자의 의도와 제작기법에 대한 연구가 동시에 진행되어야 한다. 이에 따라 17세기에 제작된 더블베이스를 대상으로 마감층을 연구하였다. 마감층은 표면관찰과 FT-IR, SEM-EDS를 이용한 정성분석을 실시하였고 바탕재인 목재 수종분석을 통해 제작자가 사용한 재료와 제작기법을 확인하였다. 목재 수종은 단풍나무류로 식별되었고 수지의 일종인 곰마라카(Gommalacca)를 주 용매인 알코올로 혼합하여 마감처리를 진행하였다. 이 결과를 바탕으로 마찌니 조반니 파올로(Maggini Giovanni Paolo) 더블베이스 마감층 제작방법을 재현하여 바이올린을 제작하였다.

• 대한한방소아과학회지
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• 제13권2호
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• pp.41-77
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• 1999

The purpose of this research is that infant artificial feeding products is used in clonic with the study on characteristic, ingredients and indication of geneal and special modified milks. The result is as follows. 1. The main ingredients of four company products-Maeil , Namyang, Pasteur, Aebout is similar but the functional is different 2. General infant formula is divided into 100days, 5-6months, 12months, 24months and 36months out of consideration for growth and development of infant. 3. The indication and sorts of the special infant formula used at a hospital is as follows. PKU-1, PKU-2 formula is available for phenylketonuria. MPA formula is available for propionic acidemia and methylmalonic acidomia. UCD is available for urea cycle disorder Leucine-free formula is available for isovaleric acidemia. Maeil LP is available for hypocalcemia. MCT formula is available for indigestion and malabsorption of fat. BCAA-free formula is available for Maple syrup urine disease. Protein-free formula is available for limit of protein uptake or mixture of peculiar amino acid or higher uptake of mineral, vitamin, calory. Methionine-free formula is available for homocystinuria and hypermethioninemia. Premature infant is available for premature and low birth weight. 4. The special infant formula published in nation is as follows. Maeil soy A, Maeil MF1, Namyang hope doctor and Maeil HA is available for diarrhea. Maeil HA, Maeil HA-21 and Namyang hope allergy is available for hypoallergy. Maeil soy A is available for diarrhea of milk allergy. Maeil MF1 or Namyang hope doctor is available for acute bacterial or viral temporal diarrhea. Maeil HA is available for allergic chronic diarrhea. Maeil HA and Namyang hope allergy as eHP-formula is available for chronic diarrhea for lactose intolerance and milk allergy. Maeil-21 as pHP-formula for neonates with allergy family, allergic symptoms such as atopic dermatitis, asthma except digestive system.

• 대한유전성대사질환학회지
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• 제11권1호
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• pp.52-73
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• 2011

Since we have started organic acid analysis on Jul. 1997, we have been collecting data about organic acidemias in Korea. The data presented here is our 3 years experience in organic acid analysis. We have collected 712 samples from major university hospitals all over the Korea, large enough for relatively accurate incidence of organic acid disorders. We are using solvent extraction method with ethylacetate, MSTFA for derivatization and quantitation of 83 organic acids simultaneously. Out of 712 patients sample, 498 patients sample (70%) showed no evidence of organic acid abnormalities. Out of 214 remaining samples we have found very diverse disorders such as methylmalonic aciduria(6), propionic aciduria (10), biotinidase deficiency (6), maple syrup urine disease (3), isovaleric aciduria (4), tyrosinemia type II (4), tyrosinemia type IV (1), glutaric aciduria type I (1), glutaric aciduria type II (22), 3-methylglutaconic aciduria type I (3), 3-methylglutaconic aciduria type III (7), HMG-CoA lyase deficiency (1), hyperglyceroluria (2), cytosolic 3-ketothiolase deficiency (55), mitochondrial 3-ketothiolase deficiency (3), 3-hydroxyisobutyric aciduria (2), L-2-hydroxyglutaric aciduria (2), fumaric aciduria (2), lactic aciduria with combined elevation of pyruvate (most likely PDHC deficiency) (28), lactic aciduria without combined elevation of pyruvate (most likely mitochondrial respiratory chain disorders) (35), SCAD deficiency (3), MCAD deficiency (1), 3-methylcrotonylglycineuria (1), orotic aciduria (most likely urea cycle disorders) (7) and 2-methylbranched chain acyl-CoA dehydrogenase deficiency (1). In conclusion, though the incidence of indivisual organic acidemia is low, the incidence of overall organic acidemia is relatively high in Korea. Most of the patients showed some signs of neurological dysfunction. In other words, organic acid analysis should be included in the diagnostic work up of all neurological dysfunctions.