• Journal of Internet Computing and Services
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• v.12 no.4
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• pp.15-26
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• 2011

As quick and secure mobility service is becoming a critical issue in the ubiquitous environment. Internet Engineering Task Force (IETF) has done a lot of meaningful work in order to cope with the critical issues, which is a key technology of guaranteeing the legally and safely using of network resources, they has proposed Hierarchical Mobile IPv6 (HMIPv6) to complement for such problems as handover latency and signaling overhead in existing MIPv6. Most of the current research about HMIPv6 focuses on how to optimize the interactive processes between the HMIPv6 and AAA (Authentication, Authorization, Accounting) protocol. This paper describes a cost-effective hierarchical authentication scheme, which makes its focus on minimizing the authentication latency in AAA processing. In this scheme, a hierarchical AAA architecture is proposed, in which the AAA servers are deployed on the Mobility Anchor Point (MAP), the Root AAA server manages several Leaf AAA servers and the Brokers on behalf of the AAA server in home domain. The simulation results shows that the proposed scheme reduces the handoff and authentication latency evidently compared to the previous traditional authentication combination modeling.

• Journal of Advanced Navigation Technology
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• v.12 no.2
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• pp.91-99
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• 2008

In this paper, we implemented an wireless remote control and monitoring system by using Globalstar satellite modem. This system is composed of the data terminal equipment of Globalstar data communication system using microcontroller, C8051F023, and WGIS(Web-based GIS) user program. We tested the wireless remote control and monitoring system with data terminal equipment and user program how to work properly, and verified that the user could confirm the data from the data terminal equipment, which can provide the status of input/output devices and the information of location with the main and control dialog by GIS(Geographic Information System) program. For data communication of between data terminal equipment and user program, we programed PPP and TCP/IP protocol to communicate with each other. Some GIS tools used in this program are ArcView and MapObject from ESRI to offer various visual mapping information to the user.

• Journal of the Korea Society of Computer and Information
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• v.12 no.6
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• pp.235-242
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• 2007

Network Mobility Basic Support protocol reduces location-update signaling by making network movements transparent to the mobile nodes (MNs) behind the mobile router (MR), but causes some problems such as sub-optimal routing and multiple encapsulations. This paper proposes an Route Optimization Employing HMIP Extension for Mobile Networks (ROHMIP) scheme for nested nubile networks support which introduces HMIP concept with relation information between MNNs behind a MR and the MR in order to localize handoff, to optimize routing and especially reduce handoff signal overhead. With ROHMIP, a mobile network node (MNN) behind a MR performs route optimization with a correspondent node (CN) as the MR sends a binding update message (BU) to mobility anchor point (MAP) via root-MR on behalf of all active MNNs when the mobile network moves. This paper describes the new mechanisms and provides simulation results which indicate that our proposal reduces transmission delay, handoff latency and signaling overhead.

• Bulletin of the Korean Chemical Society
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• v.28 no.12
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• pp.2303-2309
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• 2007

Expressed protein ligation (EPL) technique, joining recombinantly expressed proteins to polypeptides, has been widely adopted for addressing various biological questions and for drug discovery. However, joining two recombinant proteins together is sometimes difficult when proteins are expressed insoluble and unrefoldable, because ligation-active proteins via intein-fusion are obtainable when they are folded correctly. We overcame this limitation coexpressing target protein with additional methionine aminopeptidase (MAP) which enhances removal of the initiation methionine of recombinantly expressed protein. Our approach demonstrated that two domains of 46 kDa 5-Enolpyruvylshikimate-3-phosphate (EPSP) synthase, a target of herbicide glyphosate, were successfully joined by native chemical ligation, although its C-terminal domain was expressed as an inclusion body. The intein-fused N-terminal fragment of EPSP synthase (EPSPSN, residues 1-237) was expressed and the ligation-active thioester tagged N-terminal fragment (EPSPSN-thioester) was purified using a chitin affinity chromatography and mercapto-ethanesulphonate (MESNA) as intein thiolysis reagent. Its Cterminal fragment (EPSPSC, residues Met237-238CYS-427), expressed as an inclusion body, was prepared from an additional MAP-expressing strain. Protein ligation was initiated by mixing ~1 mM of EPSPSN-thioester with ~2 mM of EPSPSCCYS (residues 238CYS-427). Also we found that addition of 2% thiophenol increased the ligation efficiency via thiol exchange. The ligation efficiency was ~85%. The ligated full-length EPSP synthase was dissolved in 6 M GdHCl and refolded. Circular dichroism (CD) and enzyme activity assay of the purified protein showed that the ligated enzyme has distinct secondary structure and ~115% specific activity compared to those of wild-type EPSP synthase. This work demonstrates rare example of EPL between two recombinantly expressed proteins and also provides hands-on protein engineering protocol for large proteins.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.28 no.12A
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• pp.964-974
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• 2003

With increasing use of a personal mobile computer. the Mobile IPv6 is one of the main protocols that support mobility and complies with IPv6 specification. Similar to the mobile IPv6, the mobile IPv6 also has limitations on fast moving condition. The Hierarchical Mobile IPv6 is a solution that overcomes these limitations. The Hierarchical Mobile IPv6 is a micro mobility protocol that supports fast mobile IP handover and reduces signaling overhead with Mobility Anchor Point(MAP). But until now no paging method is applied to the Hierarchical Mobile IPv6 to reduce unnecessary signaling overhead and power consumption of mobile nodes. So, the paging mechanism for the Hierarchical Mobile IPv6 is proposed in this paper. the mechanism is implemented by making use of the destination option header and extension function and the last location algorithm. The results show that the Hierarchical Mobile IPv6 with the paging ability reduces the traffic of mobile networks by removing unnecessary binding update packet generated whenever handover takes place. Also, the larger the paging size is. the less the number of BU(Binding Update) massage generated.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.5B
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• pp.413-420
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• 2006

HMIPv6 is designed to reduce the signaling load to external network and improve handover speed of MN by including Mobility Anchor Point(MAP) in local handover. However in this case of macro handover, it's just used pervious MIPv6 handover algorithm. So, it occurs packet loss and transmission delay problem. In this paper, we propose the mechanism applying the HMIPv6 for Fast Handover to choose suitable to the condition buffering handover. The condition for the selection is result distance measurement between MN and CN, between MN and NAR. Furthermore, using F-SNOOP protocol, it is possible to improve wireless network performance. Wireless network has high Bit Error Rate(BER) characteristic because of path loss, fading, noise and interference. TCP regards such errors as congestion and starts congestion control. This congestion control makes packet transmission rate low. However, F-SNOOP improves TCP performance based on SNOOP and Freeze TCP that use Zero Window Advertisement(ZWA) message when handoff occurs in wireless network.

• Biomedical Science Letters
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• v.29 no.4
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• pp.263-273
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• 2023

This study aimed to investigate effect of scalp acupuncture (SA) and repetitive transcranial magnetic stimulation (rTMS) intervention on neuromotor function in photothrombotic cerebral infarction (PCI) rat model. Sixty male SD rats were used. PCI was induced on M1 cortex of right frontal lobe. SA was performed at the Qianding (GV21), Xuanli (GB6) acupoints of ipsilesional M1. Low-frequency rTMS was delivered to contralesional M1. All rats were randomly divided into 4 groups: group A, normal (n, 15); group B, PCI without any stimulation intervention (n, 15); group C, PCI with SA (n, 15); group D, PCI with rTMS (n, 15). Rota-rod test and Ladder rung walking test (LWT) were done weekly for 8 weeks after PCI. SA or rTMS was started from post-PCI 4^th day as protocol for 8 weeks. H/E stain and IHC were done. Western blot and qRT-PCR study were performed for MAP2 and BDNF from ipsilesional M1 peri-infarction tissue. Brain MRI study was conducted to quantify the volume of cerebral infarction. As a result, left forelimb and hindlimb function significantly improved more in group C and D than control group, with expressed more BDNF and MAP2. And brain MRI showed focal infarction of right M1 after PCI, and infarction volume progressively decreased in group C and D than group B from post-PCI 5^th to 8^th week. SA or rTMS was more effective than no intervention group on neuromotor function of PCI rat model. The functional recovery was associated with stimulation intervention-related neurogenesis.

• Journal of Korean Society of Forest Science
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• v.102 no.4
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• pp.608-616
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• 2013

The objective of this study was to suggest contingent valuation method, simple random sampling method, systematic sampling method, maximum practice area method, and overlay practice area method as the estimation methods for forest management area to estimate carbon dioxide sink by forest management as stated in Article 3.4 of the Kyoto Protocol. A case study for Chungcheongbuk-do was performed using maximum practice area method which was thought of as the most rational method within MRV(Measurable, reportable and verifiable). The forest management ratio was defined as forest management area over the total forest area. Based on the definition of forest management activity, forest area was divided into practice forest land and non-practice forest land. The area of forest mangement for practices was based on the 'National Forest Management Information System' and the history of practices from the 'Proposals on Private Management Information Database'. The area of forest management for non-practices was based on the public used forest land from 'Categorial map of forest land'. It was shown that the forest management area of Chuncheongbuk-do was 115,566 ha for practice forest land, and 131,008 ha for non-practice forest land. The forest managent ratio was 49.7% of the total forest area of 495,806 ha. This study made possible to the estimation of the forest management ratio under Kyoto Protocol, and had an advantage in searching for a practical method of forest management plan in which the forest management ratio could be enhanced.

• Journal of the Korea Society of Computer and Information
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• v.21 no.12
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• pp.11-18
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• 2016

Magnetic resonance image (MRI) is widely used in brain research field and medical image. Especially, non-invasive brain activation acquired image technique, which is functional magnetic resonance image (fMRI) is used in brain study. In this study, we investigate brain activation occurred by LED light stimulation. For investigate of brain activation in experimental small animal, we used high magnetic field 9.4T MRI. Experimental small animal is Balb/c mouse, method of fMRI is using echo planar image (EPI). EPI method spend more less time than any other MRI method. For this reason, however, EPI data has low contrast. Due to the low contrast, image pre-processing is very hard and inaccuracy. In this study, we planned the study protocol, which is called block design in fMRI research field. The block designed has 8 LED light stimulation session and 8 rest session. All block is consist of 6 EPI images and acquired 1 slice of EPI image is 16 second. During the light session, we occurred LED light stimulation for 1 minutes 36 seconds. During the rest session, we do not occurred light stimulation and remain the light off state for 1 minutes 36 seconds. This session repeat the all over the EPI scan time, so the total spend time of EPI scan has almost 26 minutes. After acquired EPI data, we performed the analysis of this image data. In this study, we analysis of EPI data using statistical parametric map (SPM) software and performed image pre-processing such as realignment, co-registration, normalization, smoothing of EPI data. The pre-processing of fMRI data have to segmented using this software. However this method has 3 different method which is Gaussian nonparametric, warped modulate, and tissue probability map. In this study we performed the this 3 different method and compared how they can change the result of fMRI analysis results. The result of this study show that LED light stimulation was activate superior colliculus region in mouse brain. And the most higher activated value of segmentation method was using tissue probability map. this study may help to improve brain activation study using EPI and SPM analysis.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2009.04a
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• pp.145-150
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• 2009

In this paper, we introduce about the implementation of geospatial database middleware for construction of next generation digital map. This middleware supports global transactions based on the distributed and heterogeneous data store circumstance, geospatial data processing which does not follow standard, global schema management, object management based UFID and large scale data process. In addition, this supports creating, managing, calling for user defined procedures that can help making business logic of middleware user. User defined procedure interface is designed using CORBA and RMI protocol. In this paper, we describe the implementation of distributed object oriented database middleware which use variable data store.