• Structural Engineering and Mechanics
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• v.13 no.2
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• pp.231-239
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• 2002

The problem of dynamic analysis of truss structures based on probability is studied in this paper. Considering the randomness of both physical parameters (elastic module and mass density) of structural materials and geometric dimension of bars respectively or simultaneously, the stiffness and mass matrixes of the elements and structure have been built. The structure dynamic characteristic based on probability is analyzed, and the expressions of numeral characteristics of inherence frequency random variable are derived from the Rayleigh's quotient. The method of structural dynamic analysis based on probability is developed. Finally, two examples are given.

• Nuclear Engineering and Technology
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• v.51 no.2
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• pp.556-560
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• 2019

To provide high shunt impendence with low power losses, an 81.25 MHz continuous wave (CW) radio frequency quadrupole (RFQ) accelerator has been designed and machined as parts of the Low Energy Accelerator Facility (LEAF). In this paper, the mechanical structure and the main processing technology of the RFQ cavities are described according to the physical and geometric parameters requirements of the RFQ. The fabrication of the RFQ has been completed and the test results agree well with the design requirements. The RFQ accelerator will work in Institute of Modern Physics, Chinese Academy of Sciences in 2018.

• Journal of Hydrospace Technology
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• v.2 no.2
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• pp.24-35
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• 1996

This paper describes parameter identification techniques formulated for the estimation of maneuvering coefficients of a submerged body. The first part of this paper is concerned with the identifiability of the system parameters. The relationship between a stochastic linear time-invariant system and the equivalent dynamic system is investigated. The second is concerned with the development of the numerically stable identification technique. Two identification techniques are tested; one is the ma7mum likelihood (ML) methods using the Holder & Mead simplex search method and using the modified Newton-Raphson method, and the other is the modified extended Kalman filter (MEKF) method with a square-root algorithm, which can improve the numerical accuracy of the extended Kalman filter. As a results, it is said that the equations of motion for a submerged body have higher probability to generate simultaneous drift phenomenon compared to general state equations and only the ML method using the Holder & Mead simplex search method and the MEKF method with a square-root algorithm gives acceptable results.

• Archives of Pharmacal Research
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• v.25 no.6
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• pp.984-988
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• 2002

The issue of whether or not the presence NOx (NO and oxidized metabolites) in the hepatocytes at pathological levels affects the functional activity of transport systems within the sinusoidal membrane was investigated. For this purpose, the effect of the pretreatment of isolated hepatocytes with sodium nitroprusside (SNP), a spontaneous NO donor, on the sinusoidal uptake of tributylmethylammonium (TBuMA) and triethylmethyl ammonium (TEMA), representative substrates of the organic cation transporter (OCT), and taurocholate, a representative substrate of the $Na^+$/taurocholate cotransporting polypeptide (NTCP), was measured. The uptake of TBuMA and TEMA was not affected by the pretreatment, as demonstrated by the nearly identical kinetic parameters for the uptake ($i.e., V_{max}, K_{m} and CL_{linear}$). The uptake of mannitol into hepatocytes was not affected, demonstrating that the membrane integrity remained constant, irregardless of the SNP prutreatment. On the contrary, the uptake of taurocholate was significantly inhibited by the pretreatment, resulting in a significant decrease in V_{max}$, thus providing a clear demonstration that NOx preferentially affects the function of NTCP rather than OCT on the sinusoidal membrane. A direct interaction between NOx and NTCP or a decrease in $Na^+/K^+$ ATPase activity as the result of SNP pretreatment might be responsible for this selective effect of NOx.

• Journal of the Korean Data and Information Science Society
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• v.26 no.4
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• pp.885-894
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• 2015

It is necessary to forecast the electricity demand for reliable and effective operation of the power system. In this study, we try to categorize a functional data, the mean curve in accordance with the time of daily power demand pattern. The data were collected between January 1, 2009 and December 31, 2011. And it were converted to time series data consisting of seasonal components and error component through log transformation and removing trend. Functional clustering by Ma et al. (2006) are applied and parameters are estimated using EM algorithm and generalized cross validation. The number of clusters is determined by classifying holidays or weekdays. Monday, weekday (Tuesday to Friday), Saturday, Sunday or holiday and season are described the mean curve of daily power demand pattern.

• Geomechanics and Engineering
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• v.15 no.5
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• pp.1029-1038
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• 2018

A superposition-iteration (S-I) model is proposed to simulate the jet grouting pre-reinforcing impact for a shallow-buried tunnel. The common model is deduced by theoretical (force equilibrium) analysis and then transformed into the numerical formulation. After applying it to an actual engineering problem, the most obvious deficiency was found to be continuous error accumulation, even when the parameters change slightly. In order to address this problem, a superposition-iteration model is developed based on the basic assumption and superposition theory. First, the additional deflection between two successive excavation steps is determined. This is caused by the disappearance of the supporting force in the excavated zone and the soil pressure in the disturbed zone. Consequently, the final deflection can be obtained by repeatedly superposing the additional deflection to the initial deflection in the previous steps. The analytical solution is then determined with the boundary conditions. The superposition-iteration model is thus established. This model was then applied and found to be suitable for real-life engineering applications. During the calculation, the error induced by the ill-conditioned problem of the matrix is easily addressed. The precision of this model is greater compared to previous models. The sensitivity factors and their impact are determined through this superposition-iteration model.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.6
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• pp.453-462
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• 2020

Chronic joint pain due to loss of cartilage function, degradation of subchondral bone, and related conditions are common plights of an arthritis patient. Antioxidant compounds could solve the problems in arthritic condition. The objective of this study was to evaluate the anti-arthritic activity of D-carvone against complete Freund's adjuvant (CFA)-induced arthritis in rats. D-carvone was orally administered for 25 days at the doses of 30 and 60 mg/kg against CFA-induced arthritic rats. Changes in body weight, paw swelling, organ index, hematological parameters, oxidative stress markers, inflammatory cytokines, and histopathology were recorded. Oral treatment of D-carvone significantly improved the body weight, reduced the paw swelling, edema formation, and organ index in arthritic rats. The levels of white blood cells were reduced, red blood cells and hemoglobin levels were improved in D-carvone treated arthritic rats. Lipid peroxidation levels were lowered whereas enzymatic and non-enzymatic antioxidants were significantly elevated by D-carvone administration against arthritic rats. D-carvone significantly modulated inflammatory cytokine levels and improved the ankle joint pathology against CFA-induced arthritic inflammation. In conclusion, D-carvone proved significant anti-arthritic activity against CFA-induced arthritis in rats.

• Knee surgery & related research
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• v.30 no.4
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• pp.293-302
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• 2018

Purpose: High tibial valgus osteotomy (HTO) is a well-established surgical procedure for patients with medial compartment osteoarthritis (OA) of the knee. The hybrid closed-wedge HTO (CWHTO) procedure permits extensive correction in patients with severe deformities or patellofemoral joint OA. The aim of this study was to report the short-term results in a consecutive series of patients treated with hybrid CWHTO. Materials and Methods: We retrospectively evaluated the clinical outcomes and radiographic parameters in 29 consecutive knees that underwent hybrid CWTHO to correct medial compartment OA at an average follow-up of 52.6 months. Clinical outcomes were assessed using the Lysholm score and knee scoring system of the Japanese Orthopedic Association (JOA). The Kellgren-Lawrence grading system and pre- and postoperative mechanical axis (MA), femorotibial angle (FTA), posterior tibial slope, and patella height were assessed. Results: The FTA and MA significantly changed from $180.7^{\circ}$ to $170.4^{\circ}$ and from $22.0^{\circ}$ to $60.2^{\circ}$, respectively. No significant differences were observed between the mean pre- and postoperative posterior tibial slope, Insall-Salvati ratio, or Caton-Deschamps index. The postoperative JOA and Lysholm scores significantly improved from 76.7 to 95.8 and from 58.8 to 90.2, respectively. Conclusions: Satisfactory outcomes can be achieved with hybrid CWHTO in patients with medial OA.

• Nuclear Engineering and Technology
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• v.51 no.1
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• pp.257-262
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• 2019

The control of microstructure is critical for the porous fuel particles used for infiltrating actinide nuclides. This study concerns the effect of heating processes on properties and microstructure of the fuel particles. The uniform gel precursor beads were synthesized by a microfluidic sol-gel process and then the porous $CeO_2$ microspheres, as a surrogate for the ceramic nuclear fuel particles, were obtained by heating treatment of the gel precursors. The fabricated $CeO_2$ microspheres have a narrow size distribution and good sphericity due to the feature of microfluidics. The effects of heating processes parameters, such as heating mode and peak temperatures on the properties of microspheres were studied in detail. An optimized heating mode and the peak temperature of $650^{\circ}C$ were selected to produce porous $CeO_2$ microspheres. The optimized heating mode can avoid the appearance of broken or crack microspheres in the heating process, and as-prepared porous microspheres were of suitable pore size distribution and pore volume for loading minor actinide (MA) solution by an infiltration method that is used for fabrication of MA-bearing nuclear fuel beads. After the infiltration process, $1000^{\circ}C$ was selected as the final temperature to improve the compressive strength of microspheres.

• Animal Bioscience
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• v.34 no.2
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• pp.205-212
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• 2021

Objective: The purpose of present study was to investigate the effects of condensed molasses fermentation solubles (CMS) on lactation performance, rumen fermentation, nutrient digestibility, and serum parameters of dairy cows. Methods: A total of 75 healthy Holstein cows with the same parity (milk production = 35±2.5 kg, body weight = 570±28 kg) were randomly selected and divided into 5 groups. One group served as control group (CON; no CMS), whereas the other 4 groups were CMS1 (accounted for 1% of the diet), CMS2 (2%), CMS3 (3%), and CMS4 (4%). All cows were fed regularly three times each day at 0800, 1600, and 2400 h. Cows received diet and water ad libitum. The experiment lasted for 60 days. Results: Results showed that the dry matter intake, milk yield, and protein of CMS2 were maximum and higher (p<0.05) than CMS4. The ruminal pH was observed less than 6 in CMS3 and CMS4 groups. No noticeable difference of microbial protein was found between CON and CMS2 groups, while the microbial protein in these groups was higher (p<0.05) than CMS3 and CMS4 groups. The apparent digestibility of dry matter, organic matter, and crude protein in CMS2 group was higher (p<0.05) than CMS3 and CMS4 groups. Compared to CMS3 and CMS4 groups, the CMS2 group increased (p<0.05) the serum concentrations of immunoglobulin G and immunoglobulin M on d 60. Conclusion: Therefore, it is practicable that CMS substitutes for a part of concentrates in lactating cows' diets, but higher addition of CMS (more than 3% of the diet) could decrease production performance of dairy cows as seen in the present study.