• BMB Reports
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• v.35 no.4
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• pp.364-370
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• 2002

The effect of sodium n-dodecyl sulphate (SDS) on hemoglobin autoxidation was studied in the presence of a 100mM phosphate buffer (pH 7.0) by different methods. These included spectorphotometry, fluorescence technique, cyclic voltametry, differential scanning calorimetry, and densitometry. Spectroscopic studies showed that SDS concentrations up to 1 mM increased deoxy-, decreases oxy-, and had no significant effect on the met- conformation of hemoglobin. Therefore, a SDS concentration up to 1 mM increased the deoxy form of hemoglobin as the folded, compact state and decreases the oxy conformation. The turbidity measurements and differential scanning calorimetry techniques indicated a more stable conformation for hemoglobin in the presence of SDS up to 1mM. Electrochemical studies also confirmed a more difficult oxidation under these conditions. The induction of the deoxy form in the presence of SDS was confirmed by densitometry techniques. The compact structure of deoxyhemoglobin blocks the formation of met-conformation in low SDS concentrations.

• Korean Journal of Optics and Photonics
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• v.5 no.1
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• pp.120-124
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• 1994

PBH-DFB-LD emitting at $1.55\mu\textrm{m}$ wavelength has been fabricated for 2.5 Gbps optical fiber communications. For fabrication of PBH-DFB-LD. inteference expose for grating formation and 3-step LPE epitaxial growth was used. Fabricated PBH-DFB-LD operates in single longitudinal mode with more than 35dB SMSR and its threshold current is less than 15 mA. The operating wavelength is 1530-1550 nm with the temperature dependence of $0.9\AA/^{\circ}C$. Coupling coefficient(K) was estimated as $$97 cm^{-1} by means of stop-band measurement. PBH-DFB-LD fabricated in this experiment can be applicable as light source for 2.5 Gbps optical fiber communication system. ystem.

• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.4
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• pp.895-900
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• 1999

We have examined the effects of mayonnaise on the lipid metabolism and calcium bioavailability of rats by using myonnaise. Sprague Dawley male rats(131$\pm$5g) were divided into four dietary groups[Control (Con, 10% soybean oil), Mayonnaise(M5), 10% Mayonnaise(M10)and 15% Mayonnaise(M15)] were fed ad libitum with experimental diets for four weeks. Final body weight exhibited a decrease in the M10 group, also final thymus organ weight showed a significant decreasing trend(p<0.05). The levels of serum, liver and adipose total lipid were significantly different among the four experimental groups(p<0.05). Serum calcium levels were significantly lower in the M15 group than in among the groups(p<0.05). On the other hand, the elevation of serum cholesterol levels were not clearly observed, but triglyceride levels were elevated the M5 and M15 group. The P/S ratio of adipose tissue were higher in the M10 group(2.35$\pm$0.35) than any other groups. Free EDTA in mayonnaise was 0.0307~0.0387%, moisture 12.46~16.49% and calcium 0.012~0.019%. But commercial mayonnaise contained free EDTA higher than the safe use (0.0075%). Safety problems of EDTA additives resulted from mass processed mayonnaise are arising. Though the evaluation of safety can not reach a conclusion with only one or two clinical case studies. It often simply jumps to conclusion. Therefore more wide ranged discussion and deepened study is required to search for the solution of safety problems.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.404-407
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• 2011

This paper presents a design of current mode PWM/PFM DC-DC Boost converter. This DC-DC Boost Converter operates with PWM mode at the heavy loads and with PFM mode at light loads. The DC-DC boost converter is designed with CMOS 0.35${\mu}m$ technology. It operates at 500KHz and can drive a load current up to 600mA. It has a maximum power efficiency of 92.1%. The total chip area is $1300{\mu}m{\times}1070{\mu}m$ including pads. The DC-DC boost converter operates in a wide range of load currents while occupying a small chip area.

• Korean Journal of Optics and Photonics
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• v.20 no.3
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• pp.175-181
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• 2009

Holographic lithography is one of the potential technologies for next generation lithography which can print large areas (6") as well as very fine patterns ($0.35{\mu}m$). Usually, photolithography has been developed with two target purposes. One was for LCD applications which require large areas (over 6") and micro pattern (over $1.5{\mu}m$) exposure. The other was for semiconductor applications which require small areas (1.5") and nano pattern (under $0.2{\mu}m$) exposure. However, holographic lithography can print fine patterns from $0.35{\mu}m$ to $1.5{\mu}m$ keeping the exposure area inside 6". This is one of the great advantages in order to realize high speed fine pattern photolithography. How? It is because holographic lithography is taking holographic optics instead of projection optics. A hologram mask is the key component of holographic optics, which can perform the same function as projection optics. In this paper, Surface-Relief TIR Hologram Mask technology is introduced, and enables more robust hologram masks than those previously reported that were formed in photopolymer recording materials. We describe the important parameters in the fabrication process and their optimization, and we evaluate the patterns printed from the surface-relief TIR hologram masks.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.31 no.4
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• pp.350-361
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• 1995

For the Purpose of the measurement of drifting condition of the anchovy drift gill net, some experiments were carried out in M. S Seong-Yang at the near sea of Kampo harbor in Korean east sea from August to October 1994, by using three set of GPS equipped with her net. The main results obtained are as follows : 1) In fixed position by GPS at Taebyon, the radius of 95% probability and shifted distance from standard position were respectively 79.8m, 21.0m. 2) The mean values of PDOP and HDOP of GPS at Taebyon were respectively 3.5, 1.9 and the stability of the position by GPS at Taebyon was found to be very high. 3) In the fishing ground of the position from Lat. $35^{\circ}$ 41.5'N to $Lat^{\circ}$. 43.5', from Long. $129^{\circ}$ 32.0'E to Long. $129^{\circ}$ 32.5'E, the direction of the whole stretched drift gill net was $190^{\circ}$ and the direction of the whole casted net was $200^{\circ}$ when casting the net was finished. When whole net was found to be drifting into the direction of $170^{\circ}\;to\;180^{\circ}$, and the mean drifting speed of that was 0.82kt. 4) In the fishing ground of the position from Lat. $35^{\circ}$ 44.0'N to Lat. $35^{\circ}$ 45.2'N, from Long. $129^{\circ}$ 30.1'E to Long. $129^{\circ}$ 31.2'E, the direction of the whole stretched net was 20$^{\circ}$ and the direction of the whole stretched net was $20^{\circ}$ when casting the net was finished. When hauling the net, the direction of the spreaded net appeared from the North into the South and the whole net was found to be drifting into the direction of $210^{\circ}\;to\;220^{\circ}$, and the mean drifting speed of that was 0.75kt. 5) In the fishing ground of the positioning from Lat. $35^{\circ}$ 44.9'N to Lat. $35^{\circ}$ 46.0'N, Long. $129^{\circ}$ 33.0'E to Long. $129^{\circ}$ 34.0'E, the direction to the whole stretched net was $35^{\circ}$ and the direction of the whole casted net was $50^{\circ}$ when casting the net was finished. When hauling the net, the direction of the spreaded net appeared into the South from the East and the whole net was found to be drifting into the direction of $330^{\circ}\;to\;40^{\circ}$, and the mean drifting speed of the was 0.63kt.

• The Korean Journal of Zoology
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• v.35 no.4
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• pp.489-496
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• 1992

The karyotypes of 4 Korean Myotis species (M. mystucinus gracilis, M. jormous tsuensis, M. duubentonii ussuriensis and M. macrodoctvlusp and 2 Pipistrelfus species (p. coreensis and p. abramusl belonging to the Vespertilionidae were examined. The 4 Mvotis species had the karyotypes of 2n : 44 with FN : 50 (M. m. gracilis and M. f. tsuensisl or 52 (M. d. ussuriensis and M. mncrodactylus). Furthermore the karyotype of R obrumus (2n : 26, FN : 441 seemed advanced compared with that of U coreensis (2n : 44, FN : 501 which is similar to the original karyotype of Mvotis species (2n : 44, FN : 50).

• Korean Journal of Medicinal Crop Science
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• v.20 no.1
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• pp.8-15
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• 2012

The present study investigated an ethanol extract of Chaenomeles sinensis fruit (CSF) for possible neuroprotective effects on neurotoxicity induced by amyloid ${\beta}$ protein ($A{\beta}$) (25-35) in cultured rat cortical neurons and also for antidementia activity in mice. Exposure of cultured cortical neurons to $10{\mu}M\;A{\beta}$ (25-35) for 36 h induced neuronal apoptotic death. At $0.1-10{\mu}g/m{\ell}$, CSF inhibited neuronal death, elevation of intracellular calcium concentration ($[Ca^{2+}]_i$), and generation of reactive oxygen species (ROS) induced by $A{\beta}$ (25-35) in primary cultures of rat cortical neurons. Memory loss induced by intracerebroventricular injection of mice with 15 nmol $A{\beta}$ (25-35) was inhibited by chronic treatment with CSF (10, 25 and 50 mg/kg, p.o. for 7 days) as measured by a passive avoidance test. CSF (50 mg/kg) inhibited the increase of cholinesterase activity in $A{\beta}$ (25-35)-injected mice brain. From these results, we suggest that the antidementia effect of CSF is due to its neuroprotective effect against $A{\beta}$ (25-35)-induced neurotoxicity and that CSF may have a therapeutic role for preventing the progression of Alzheimer's disease.

• Journal of Sensor Science and Technology
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• v.5 no.2
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• pp.1-8
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• 1996

In this paper, We have designed silicon pressure sensor with center-bossed diaphragm which improving sensitivity and linearity by reducing diaphragm deflection. Designed center-bossed pressure sensor showed maximum deflection of $0.125{\mu}m$, maximum stress of $2.24{\times}10^7 Pa$ and sensitivity of 27.67 mV/V.psii. As a result, diaphragm deflection was reduced to 1/160 that of diaphragm thickness and 1/35 that of square diaphragm. Also, sensitivity was increased 19 times compared to square diaphragm.

• Korean Journal of Microbiology
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• v.30 no.3
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• pp.213-217
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• 1992

Glucosyltransferase of Streptococcus mutans NCTC 10449 was purified and characterized. It relates with production of insoluble glucan in dental caries. The molecular weight was estimated to be 152.000. The optimum pH and temperature was 6.5 and $35^{\circ}C$. respectively. The enzyme was stable in alkaline pH. The Michaelis constants of the enzyme for releasing of fructose were 48 mM. Hydrolysis rate of insolut~le glucan by tlextranase was higher in S. mutuns NCTC 10449 than that of strains isolated from saliva.