• 한국재료학회지
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• 제22권7호
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• pp.342-345
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• 2012

The dielectric properties and phase transformation of poled <001>-oriented $Pb(Mg_{1/3}Nb_{2/3})O_3-x%PbTiO_3$(PMN-x%PT) single crystals with compositions of x = 20, 30, and 35 mole% are investigated for orientations both parallel and perpendicular to the [001] poling direction. An electric-field-induced monoclinic phase was observed for the initial poled PMN-30PT and PMN-35PT samples by means of high-resolution synchrotron x-ray diffraction. The monoclinic phase appears from $-25^{\circ}C$ to $100^{\circ}C$ and from $-25^{\circ}C$ to $80^{\circ}C$ for the PMN-30PT and PMN-35PT samples, respectively. The dielectric constant (${\varepsilon}$)-temperature (T) characteristics above the Curie temperature were found to be described by the equation$(1/{\varepsilon}-1/{\varepsilon}_m)^{1/n}=(T-T_m)/C$, where ${\varepsilon}_m$ is the maximum dielectric constant and $T_m$ is the temperature giving ${\varepsilon}_m$, and n and C are constants that change with the composition. The value of n was found to be 1.82 and 1.38 for 20PT and 35PT, respectively. The results of mesh scans and the temperature-dependence of the dielectric constant demonstrate that the initial monoclinic phase changes to a single domain tetragonal phase and a to paraelectric cubic phase. In the ferroelectric tetragonal phase with a single domain state, the dielectric constant measured perpendicular to the poling direction was dramatically higher than that measured in the parallel direction. A large dielectric constant implies easier polarization rotation away from the polar axis. This enhancement is believed to be related to dielectric softening close to the morphotropic phase boundary.

• 한국측량학회지
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• 제35권6호
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• pp.563-572
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• 2017

본 연구의 목적은 회전익 UAV를 이용하여 1cm 미만의 GSD를 갖는 초고해상도 영상을 취득하기 위해 비행고도, 비행속도, 카메라 셔터의 노출시간, 자동초점조절 사용 여부가 영상의 시각적 해상도에 미치는 영향을 객관적으로 분석하는 것이다. 아울러 다양한 형태의 항공표적에 대한 인식 용이성을 평가하는 것도 목표로 한다. 이를 위해 35mm 크기의 7952*5304 화소 CMOS 센서와 55mm 단렌즈를 이용하여 비행고도 20m부터 120m에서 20m 간격으로 촬영하고 영상의 시각적 해상도를 분석하였다. 결과로 자동초점조절을 사용한 경우 시각적 해상도는 이론적인 GSD에 비하여 1.1~1.6배로 나타났고, 자동초점조절을 사용하지 않은 경우 1.5~3.5배로 나타났다. 다음으로 비행고도 80m에서 5m/s로 정속 비행하면서 카메라의 노출 시간을 1/60sec에서 1/2000sec까지 1/2씩 줄이면서 촬영하고 시각적 해상도를 분석하였다. 허용 흐려짐을 1 화소로 가정할 때 최장 노출 시간을 준수한 경우 시각적 해상도 는 이론적인 GSD이 비하여 1.3~1.5배로 나타났고, 초과한 경우 1.4~3.0배로 나타났다. A4 용지에 항공표적을 출력하여 비행고도 80m 이내에서 촬영하면 상용소프트웨어를 이용하여 코드화된 항공표적을 자동으로 인식할 수 있으며, 자동 인식이 불가능한 고도에서도 다양한 형태의 일반 항공표적 및 코드화된 항공표적을 큰 어려움 없이 수동으로 인식할 수 있었다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5957-5961
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• 2015

Background: We designed this randomized controlled trial (RCT) to assess whether lobaplatin-based concurrent chemotherapy might be superior to cisplatin-based concurrent chemotherapy for FIGO stage II and III cervical cancer in terms of efficacy and safety. Materials and Methods: This prospective, open-label RCT aims to enroll 180 patients with FIGO stage II and III cervical cancer, randomly allocated to one of the three treatment groups (cisplatin $15mg/m^2$, cisplatin $20mg/m^2$ and lobaplatin $35mg/m^2$), with 60 patients in each group. All patients will receive external beam irradiation (EBRT) and high-dose-rate intracavitary brachytherapy (HDR-ICBT). Patients in cisplatin $15mg/m^2$ and $20mg/m^2$ groups will be administered four cycles of $15mg/m^2$ or $20mg/m^2$ cisplatin intravenously once weekly from the second week to the fifth week during EBRT, while patients inthe lobaplatin $35mg/m^2$ group will be administered two cycles of $35mg/m^2$ lobaplatin intravenously in the second and fifth week respectively during pelvic EBRT. All participants will be followed up for at least 12 months. Complete remission rate and progression-free survival (PFS) will be the primary endpoints. Overall survival (OS), incidence of adverse events (AEs), and quality of life will be the secondary endpoints. Results: Between March 2013 and March 2014, a total of 61 patients with FIGO stage II and III cervical cancer were randomly assigned to cisplatin $15mg/m^2$ group (n=21), cisplatin $20mg/m^2$ group (n=21) and lobaplatin $35mg/m^2$ group (n=19). We conducted a preliminary analysis of the results. Similar rates of complete remission and grades 3-4 gastrointestinal reactions were observed for the three treatment groups (P=0.801 and 0.793, respectively). Grade 3-4 hematologic toxicity was more frequent in the lobaplatin group than the cisplatin group. Conclusions: This proposed study will be the first RCT to evaluate whether lobaplatin-based chemoraiotherapy will have beneficial effects, compared with cisplatin-based chemoradiotherapy, on complete remission rate, PFS, OS, AEs and quality of life for FIGO stage II and III cervical cancer.

• Journal of Applied Biological Chemistry
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• 제63권3호
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• pp.259-265
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• 2020

두충나무(Du-zhong, Eucommia ulmoides Oliver)의 잎과 껍질로 부터 얻어진 50% 에탄올 추출물의 항산화 활성을 확인하였다. 두충나무 잎과 껍질 추출물의 수율은 각각 8.1±0.31과 17.4±0.89%, 총 폴리페놀 함량은 각각 64.1±3.35와 42.4±2.38 ㎍ GAE/mg, 총 플라보노이드 함량은 각각 24.0±3.15와 36.7±3.18 ㎍ QE/mg으로 나타났다. 두충나무 잎과 껍질 추출물은 농도에 비례하여 양이온라디칼, 유리라디칼과 아질산염을 소거하였고, 환원력을 증가시켰으며 지질과산화를 억제하였다. 두충나무 잎과 껍질 추출물의 ABTS 양이온라디칼 소거에 대한 EC₅₀값은 각각 560.6±17.65와 1,357.4±8.45 ㎍/mL이었고, DPPH 유리라디칼 소거에 대한 EC₅₀값은 각각 574.2±14.70과 2,103.1±108.59 ㎍/mL로 나타났다. 또한 두충나무 잎과 껍질 추출물의 환원력에 대한 EC₅₀값은 각각 319.9±13.42와 705.9±26.08 ㎍/mL였고, 아질산염 소거에 대한 EC₅₀값은 각각 2,329.2±35.11과 5,467.6±243.92㎍/mL로 나타났다. 두충나무 잎 추출물은 74.8 ㎍/mL의 농도에서, 껍질 추출물은 177.2 ㎍/mL의 농도에서 linoleic acid의 과산화를 각각 70.0 및 79.1% 억제하였다. 두충나무 잎 추출물은 껍질 추출물에 비해 높은 항산화 활성을 보유하고 있었다.

• 전기전자학회논문지
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• 제7권2호
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• pp.236-244
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• 2003

본 논문에서는 기존에 값비싼 BiCMOS 공정으로 주로 구현되던 이동통신 단말기용 RF단 및 IF단 회로들을 CMOS 회로로 설계하고, 최종적으로 PCS 대역 송신용 CMOS RF/IF 단일 칩을 설계하였다. 설계된 회로는 IF PLL 주파수합성기, IF Mixer, VGA등을 포함하는 IF 단과, SSB RF Mixer 블록과 구동 증폭기를 포함하는 RF 단으로 구성되며, 디지털 베이스밴드와 전력증폭기 사이에 필요한 모든 신호처리를 수행한다. 설계된 IF PLL 주파수합성기는 100kHz의 옵셋 주파수에서 -114dBc/Hz의 위상잡음 특성을 보이며, lock time은 $300{\mu}s$보다 작고, 3V 전원에서 약 5.3mA의 전류를 소모한다. IF Mixer 블록은 3.6dB의 변환이득과 -11.3dBm의 OIP3 특성을 보이며, 3V 전원에서 약 5.3mA의 전류를 소모한다. VGA는 모든 이득 설정시 3dB 주파수가 250MHz 보다 크며, 약 10mA의 전류를 소모한다. 설계된 RF단 회로는 14.93dB의 이득, 6.97dBm의 OIP3, 35dBc의 image 억압, 31dBc의 carrier 억압 등의 특성을 보이며, 약 63.4mA의 전류를 소모한다. 설계된 회로는 현재 $0.35{\mu}m$ CMOS 공정으로 IC 제작 중에 있다. 전체 칩의 면적은 $1.6㎜{\times}3.5㎜$이고 전류소모는 84mA이다.

• 마이크로전자및패키징학회지
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• 제13권4호
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• pp.57-63
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• 2006

칩 스택 패키지의 삼차원 interconnection에 적용을 위해 폭 $75{\sim}10\;{\mu}m$, 길이 3mm의 트랜치 비아에 대해 전기도금전류밀도 및 전류모드에 따른 Cu filling 특성을 분석하였다. 직류모드로 $1.25mA/cm^{2}$에서 Cu filling한 경우, 트랜치 비아의 폭이 $75{\sim}35{\mu}m$ 범위에서는 95% 이상의 높은 Cu filling ratio를 나타내었다. 직류 전류밀도 $2.5mA/cm^{2}$에서 Cu filling한 경우에는 $1.25mA/cm^{2}$ 조건에 비해 열등한 Cu filling ratio를 나타내었으며, 직류모드에 비해 펄스모드가 우수한 Cu filling 특성을 나타내었다.

• 한국동물생명공학회지
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• 제35권1호
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• pp.12-20
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• 2020

Cell adhesion plays an important role in the differentiation of the morphogenesis and the trophectoderm epithelium of the blastocyst. In the porcine embryo, CDH1 mediated adhesion initiates at compaction before blastocyst formation, regulated post-translationally via protein kinase C and other signaling molecules. Here we focus on muscle RAS oncogene homolog (M-RAS), which is the closest relative to the RAS related proteins and shares most regulatory and effector interactions. To characterize the effects of M-RAS on embryo compaction, we used gain- and loss-of-function strategies in porcine embryos, in which M-RAS gene structure and protein sequence are conserved. We showed that knockdown of M-RAS in zygotes reduced embryo development abilities and CDH1 expression. Moreover, the phosphorylation of ERK was also decreased in M-RAS KD embryos. Overexpression of M-RAS allows M-RAS KD embryos to rescue the embryo compaction and blastocyst formation. Collectively, these results highlight novel conserved and multiple effects of M-RAS during porcine embryo development.

• 한국식품영양학회지
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• 제35권4호
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• pp.259-267
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• 2022

The purpose of this study was to evaluate the antioxidative activities of jeolpyun containing Cnidium officinale M extract (2%, 4%, 6%, 8%) by total polyphenol contents, electron donating ability on 2,2-diphenyl-1-picrylhydrazyl (DPPH), scavenging ability of superoxide anion radical and decomposing ability of hydrogen peroxide. In chromaticity analysis, the brightness significantly decreased with increasing Cnidium officinale M extract content. Jeolpyun containing 8% Cnidium officinale M extract revealing the highest value for the redness and the yellowness, 1.07, 12.70, respectively. The total polyphenol contents of jeolpyun containing 8% Cnidium officinale M extract were the highest content of 4,213 ㎍ gallic acid equivalent (GAE)/mL. The total polyphenol contents revealed significant difference (p<0.05). Jeolpyun containing 8% Cnidium officinale M extract revealing the highest electron donating ability (83.55%). The electron donating abilities were significantly related at p<0.05. The scavenging abilities of superoxide anion radical for jeolpyun containing 4% Cnidium officinale M extract revealed the highest ability (0.01676). There was no significant difference. The hydrogen peroxide decomposing ability for jeolpyun containing 8% Cnidium officinale M extract revealed the most hydrogen peroxide decomposing ability (-0.193) and the hydrogen peroxide decomposing ability revealed a significant difference (p<0.05).

• 전력전자학회:학술대회논문집
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• 전력전자학회 2013년도 전력전자학술대회 논문집
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• pp.443-444
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• 2013

This paper deals with development of 35hp Electric Tractor. First, Motor and inverter are designed and manufactured suitable for the 35hp diesel tractor. Then these are apply to electric tractor. Also, We confirm performance of electric tractor as driving and field operating test.

• Ocean and Polar Research
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• 제35권1호
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• pp.51-61
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• 2013

Two surveys were conducted in January 2006 and September 2007 with multibeam echosounder to investigate the dune shape, migration rate, and bedload transport rate using dune-tracking method on an offshore sand ridge at southern Gyeonggi Bay. The migration rates of dunes range from 1.8 $myr^{-1}$) to 56.0 $myr^{-1}$), at the upper northwestern side of sand ridge towards the southwest direction and from the center of the sand ridge towards the northeast direction respectively. Large (i.e. length 10-100 m) dunes show faster migration (0.3-23.4 $myr^{-1}$) ) than very large (i.e. length > 100 m) dunes because larger dunes have required a larger volume of sediments to be displaced. The decreases in dimensions and migration rates of dunes from the center of sand ridge to the lower part of southeastern side on the sand ridge can be ascribed to the decrease of sandy sediments availability, tidal currents with depth, and the coarsening of surface sediments from the crest of the sand ridge to the trough. Bedload transport rates on the basis of migration rates and dune dimensions decrease from 74.5 $m^2yr^{-1}$) at C transect to 35.6 $m^2yr^{-1}$) at R-02 transect.