• Tuberculosis and Respiratory Diseases
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• v.51 no.3
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• pp.201-210
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• 2001

Background : Approximately 10-13% of patients with interstitial lung disease(ILD) die of lung cancer, and patients with ILD have been reported to have a 7 fold higher incidence of lung cancer compared to the normal population. Recently, overexpression of the p53 and p21 proteins were observed in the epithelial cells from pathologic specimens of ILD. Overexpression of these proteins may result from chronic or recurrent DNA damage by unknown causes of inflammation. However, these proteins may also contribute to oncogenesis if other genetic alterations such as K-ras are superimposed. Methods : Immunohistochemical stains for p53 and K-ras proteins were performed with pathologic specimens from 38 cases with ILD(M/F : 27/11, mean agea : $54{\pm}10$ years) and from 10 control subjects. Results : The p53 protein was expressed in 21.1% (8/38 ILD cases) and K-ras protein expression was observed in 65.8% (25/38 ILD cases). However, neither p53 nor the K-ras protein staining was observed in the control subjects. Conclusion : A significant proportion of cases with ILD expressed the p53 and K-ras proteins in their bronchial epithelial cells. These proteins may be potentially oncogenic with the addition of further genetic alterations. However, to clarify the significance of these findings, further studies looking for correlations with the incidence of lung cancer and other genetic changes are needed.

• The korean journal of orthodontics
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• v.37 no.3 s.122
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• pp.171-181
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• 2007

Objective: The present study was aimed at an analytical formulation of the micro-implant related torque as a function of implant size, i.e. the diameter and length, screw size, and the bony resistance at the implant to bone interface. Methods: The resistance at the implant to cancellous bone interface $(S_{can})$ was assumed to be in the range of 1.0-2.5 MPa. Micro-implant model of Absoanchor (Dentos Inc. Daegu, Korea) was used in the course of the analysis. Results: The results showed that the torque was a strong function of diameter, length, and the screw height. As the diameter increased and as the screw size decreased, the torque index decreased. However the strength index was a different function of the implant and bone factors. The whole Absoanchor implant models were within the safe region when the resistance at the implant/cancellous bone $(=S_{can})$ was 1.0 or less. Conclusion: For bone with $S_{can}$ of 1.5 MPa, the cervical diameter should be greater than 1.5 mm if micro-implant models of 12 mm long are to be placed. For $S_{can}$ of 2.0 MPa, micro-implant models of larger cervical diameter than 1.5 mm were found to be safe only if the endosseous length was less than 8 mm.

• Korean Journal of Environment and Ecology
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• v.16 no.1
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• pp.34-45
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• 2002

Of the four tidal flat areas(Yeocha-ri, Dongmak-ri, Sundu-ri and Donggum-ri) on Southern Ganghwa Island, the distribution of migratory waterbirds showed a difference in the numbers of individuals and species. Higher numbers of individuals and species were observed on the Yeocha-ri tidal flat. The dominant waterbirds species at the four areas was the Dentin(Calidris alpina). This species showed an occupancy rate(42.0-79.1%) on the Yeocha-ri tidal flat, which was much higher relative to the other areas. The Yeocha-ri tidal flats were higher relative to MSL than the other tidal flats. When the Dongmak-ri tidal flat was covered by sea water, the Yeocha-ri tidal flat was 0.0317$\textrm{km}^2$ in area and on this space we observed many resting waterbirds. The biomass of the waterbirds' potential prey on the Yeocha-ri tidal flat was higher(1.6~2.5$\times$) than other tidal flats. Twenty-three species and 266 individuals were found on the Yeocha-ri tidal flat, which was higher than the tidal flats. The food of Dunlin, which was the dominant species in these four areas, was mainly Reticunassa festiva and Umbonium thomasi(Gastropoda) and Perinereis aibuitensis(Polychaeta). A Dunlin(38.11g) used to eat 1,295 individuals of these food items for daily basal energy. Gastropod, its density was highest on Yeocha-ri tidal flats. The distribution of waterbirds seemed to be closely related with the distribution of the benthos, space and safety of resting site. We suggest that the environments of tidal flats, which are rich foraging habitats, are important factors for conservation of waterbirds.

• Korean Journal of Food Science and Technology
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• v.48 no.2
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• pp.147-152
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• 2016

This study was conducted to investigate the physicochemical quality properties and provide basic data for the activation of traditional Kamju of juice type product prepared by mixing malt and extruded rice collet powder. Malt extracts were prepared by extracting the mixture of malt and water at a weight ratio of 25:75 after soaking for 2 h at $45^{\circ}C$. Rice collet powder was prepared by adjusting the barrel temperature to $95^{\circ}C$, screw speed to $3.07{\times}g$, discharge port diameter to 7 mm and a raw material input to 50 kg/h, the powder was then ground to a particle size of 80 mesh. The physicochemical characteristics (pH, color, viscosity, reducing sugars, number of viable cells, free amino acids) and sensory evaluations were conducted at various time points during the saccharification and at different mixing ratios of the extruded rice collet powder to malt extract (5:95, 15:85, 25:75, 35:65, each at $55^{\circ}C$ for 9 h). As a result, with an increase in the proportion of the extruded rice collet powder and saccharification time, the physicochemical properties of traditional Kamju significantly improved (p<0.05). A mixing ratio of 35:65 rice collet powder to malt extract and a saccharification time of 9 h were found to be the most desirable conditions. However, based on the sensory evaluation, a mixing ratio of rice collet powder and malt extract of 25:75 and a saccharification time of 5 h resulted in the most preferable palatability of traditional Kamju (p<0.05). Therefore, the mixing ratio and saccharification time should be determined to provide a better choice with respect to the taste and economic aspects of traditional Kamju.

• Journal of Life Science
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• v.26 no.4
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• pp.419-430
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• 2016

Powdery mildew disease caused by Podosphaera xanthii is a major concern for Cucumis melo production worldwide. Knowledge on genetic behavior of the related genes and their modulating phytohormones often offer the most efficient approach to develop resistance against different diseases. Mildew Resistance Locus O (MLO) genes encode proteins with seven transmembrane domains that have significant function in plant resistance to powdery mildew fungus. We collected 14 MLO genes from ‘Melonomics’ database. Multiple sequence analysis of MLO proteins revealed the existence of both evolutionary conserved cysteine and proline residues. Moreover, natural genetic variation in conserved amino acids and their replacement by other amino acids are also observed. Real-time quantitative PCR expression analysis was conducted for the leaf samples of P. xanthii infected and phyto-hormones (methyl jasmonate and salicylic acid) treated plants in melon ‘SCNU1154’ line. Upon P. xanthii infection using 7 different races, the melon line showed variable disease reactions with respect to spread of infection symptoms and disease severity. Three out of 14 CmMLO genes were up-regulated and 7 were down-regulated in leaf samples in response to all races. The up- or down-regulation of the other 4 CmMLO genes was race-specific. The expression of 14 CmMLO genes under methyl jasmonate and salicylic acid application was also variable. Eleven CmMLO genes were up-regulated under salicylic acid treatment, and 7 were up-regulated under methyl jasmonate treatments in C. melo L. Taken together, these stress-responsive CmMLO genes might be useful resources for the development of powdery mildew disease resistant C. melo L.

• Journal of the Korean earth science society
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• v.38 no.4
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• pp.269-282
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• 2017

In this study, the surface broadband emissivity ($3.0-14.0{\mu}m$) was calculated using the multiple linear regression model with narrow bands (channels 29, 30, and 31) emissivity data of the Moderate Resolution Imaging Spectroradiometer (MODIS) on Earth Observing System Terra satellite. The 307 types of spectral emissivity data (123 soil types, 32 vegetation types, 19 types of water bodies, 43 manmade materials, and 90 rock) with MODIS University of California Santa Barbara emissivity library and Advanced Spaceborne Thermal Emission & Reflection Radiometer spectral library were used as the spectral emissivity data for the derivation and verification of the multiple linear regression model. The derived determination coefficient ($R^2$) of multiple linear regression model had a high value of 0.95 (p<0.001) and the root mean square error between these model calculated and theoretical broadband emissivities was 0.0070. The surface broadband emissivity from our multiple linear regression model was comparable with that by Wang et al. (2005). The root mean square error between surface broadband emissivities calculated by models in this study and by Wang et al. (2005) during January was 0.0054 in Asia, Africa, and Oceania regions. The minimum and maximum differences of surface broadband emissivities between two model results were 0.0027 and 0.0067 respectively. The similar statistical results were also derived for August. The surface broadband emissivities by our multiple linear regression model could thus be acceptable. However, the various regression models according to different land covers need be applied for the more accurate calculation of the surface broadband emissivities.

• Korean Journal of Soil Science and Fertilizer
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• v.6 no.4
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• pp.221-226
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• 1973

In order to investigate the silica effect of insufficient wollastonite to the official standard (above than 15% of suluble silica (N/2 HCl) on rice plant as silica fertilizer, 9 kinds of wollastonites and slag were adopted to examine the amount of silica absorbed by rice straw during growing period, and soluble silica of wollastonites extracted by 7 buffer solutions were compared with silica content in rice straw. Crystalls of ingredient in wollastonite ores were identified by X-ray diffractometer. The results were that silica content of rice plant at growing stages were increased as same ratio of soluble silica. content in wollastonite. Wollastonite containing more than 10% of souble silica (N/2 HCl) could be applied as fertilizer because absorbed amount of silica by rice plant from them are higher than from slag which contained 30% of soluble silica. Wollastonite powder mixed with impure ores in which soluble silica could not be extracted had the same effect on silica absorption of straw as wollastonite powder which contained conformable amount of soluble silica. The soluble silica of wollastonite extracted by buffer solutions (2% citric acid, N. NaOAc, N. $NH_4OAc$, Petermann solution, 0.1M. EDTA, and Hot water) had high significant relation to silica content in rice straw, but soluble silica extracted N/2 hydrochloric acid solutilon, also, had deep relation to them in rice straw. The adequate solution to extract silica from wollastonites is N/2 hydrochloric acid solution because its extracted silia amount is much higher than other solution (about one hundred times) and can be determined by gravimetric analysis. X-ray diffraction pattern would identify qualitatively purity of wollastonite, and large amount of soluble silica was extracted from wollastonite which was appeared to be weathered.

• The Korean Journal of Ecology
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• v.24 no.5
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• pp.281-288
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• 2001

The relationships between the growths of Abies koreana W. and climatic factors were analyzed by the use of tree-ring analysis at the subalpine belt of Mt. Halla National Park. The four cores were extracted from each 21 trees at north-facing slope (1,900m a.s.1.). The site chronology was established on the periods from 1912 to 1999. The growth of A. koreana was very poor, in particular in the years of 1982, 1988 and 1996. Simple correlation was employed to analyze the relationship between the growth of A. koreana and climatic factors. The result of simple correlation indicates that the growth of A. koreana represent positive correlations both with the mean temperatures of April and previous November, and the precipitation of previous December and January. The presence of large number of frost-damaged scars in the individual trees of A. koreana implies that local freezing temperature conditions at Mt. Halla have occurred in 1964, 1965 and 1966. The correlations between the fir chronology SOI(Southern Oscillation Index) of previous January, February and November were significantly positive. The growth ratio of A. koreana demonstrates that this species is sensitive to seasonal variations. As the winter temperature rises, the growth ratio of A. koreana decreases, on the other hand, the increase of autumn temperature accelerates the growth ratio of A. koreana. The growth decline of A. koreana was observed from 51 cores out of the 54 cores, and the overall growth declines have initiated at 1978, 1982 and 1988. Distinct growth decline of A. koreana in the range of 70% is noticed at 34 cores out of the 51 cores. The decline of, A. koreana growth appears to be related to the winter temperature which has increased since mid-1970s.

• The Korean Journal of Ecology
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• v.25 no.5
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• pp.341-348
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• 2002

Correlations among the island area, distance to mainland, latitude, longitude, human impacts, diversity and composition of vascular plants were investigated by analyzing data on 261 islands(10.3% of total number of islands in Korea) selected from the annual reports for 'the natural evironment survey of the uninhabited islands in Korea' published by 'Ministry of Environment' during three years from 1999. The area of surveyed 261 islands ranged 1,100 to 961,000㎡(average of 75,000㎡), and the distance to mainland ranged 0.15 to 51.5km (average of 14.9km). Total number of plant species recorded in those islands was 1,109 species throughout 30 families, and mean mumber of plant species of each island was 98.7 species. Native species were 1,003 species (90.4%), and exotic species were 106 species(9.6%). The families with the largest number of species was the Compositae with 114 species, and followed in the order of Gramineae(90), Leguminosae(54), and Rosaceae(53). The result of multi-dimensional scaling analysis based on the plant species composition showed that 261 islands were distinctly divided into two groups, western sea group(131 islands) and southern sea group(130 islands). The islands of western sea group(average area of 93,000㎡) had greatly larger area than them of southern sea group(average area of 57,000㎡), but the average number of species (average species of 192) per island were less than in southern sea group (average species of 233). And, the partitioning into two groups was responsible for the species restricted to southern than to western sea group. Therefore, this results suggest that the distribution pattern and the composition of plant species could be also affected by the latitude of the island. When the species-area model was applied to total island and plant species, these results indicate that the island area was the most significant predictor of plant species diversity, and the distance to mainland and the human impacts were also shown to be significant predictors of plant species richness. But when applied to both groups of islands by the stepwise selection method, the result showed that islands of southern sea group were greatly affected by the factors such as human impacts, distance to mainland and longitude than western sea group. For the purpose of conservation of natural ecosystem on the uninhabited islands in Korea, we will also examine how the human impacts and the invasion of exotic plant species will disturb the native species diversity.

• Journal of Animal Environmental Science
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• v.13 no.2
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• pp.113-120
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• 2007

This study was conducted to measure Nitrogen(N), Phosphate($P_2O_5$), Potassium ($K_2O$), Organic matter(OM) and Moisture content of liquid pig manure by Near Infrared Spectroscopy(NIRS) and to develop an alternative and analytical instrument which are used for measurement of N, $P_2O_5$, $K_2O$, OM, and Moisture contents for liquid pig manure. The liquid pig manure sample's transmittance spectra were measured with a NIRS in the wavelength range of 400 to 2,500 nm. Multiple linear regression and partial least square regression were used for calibrations. The correlation coefficient(RSQ) and standard error of calibration(SEC) obtained for nitrogen were 0.9190 and 2.1649, respectively. The RSQ for phosphate, potassium, organic matter and moisture contents were 0.9749, 0.5046, 0.9883 and 0.9777, and the SEC were 0.5019, 1.9252, 0.1180 and 0.0789, respectively. These results are indications of the rapid determination of components of liquid pig manure through the NIR analysis. The simple analytical instrument for liquid pig manure consisted of a tungsten halogen lamp for light source, a sample holder, a quartz cell, a SM 301 spectrometer for spectrum analyzer, a power supply, an electronics, a computer and a software. Results showed that the simple analytical instrument that was developed can approximately predict the phosphate, organic matter and moisture content of the liquid pig manure when compared to the analysis taken by NIRS. The low predictability value of potassium however, needs further investigation. Generally, the experiment proved that the simple analytical instrument was reliable, feasible and practical for analyzing liquid pig manure.