• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2008년도 추계학술발표대회
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• pp.846-848
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• 2008

최근들어 MPSoC 프로그래밍 방법에 대한 많은 연구들이 이루어지고 있다. 예전부터 연구가 진행된 모델 기반 프로그래밍 접근이나 UML 같은 모델기반 언어부터 최근에 많이 연구되고 있는 MPI[1] 나 OpenMP[2] 기반의 프로그래밍 방법, 그리고 그 외에도 다양한 접근 방식의 방법론이 연구되어 있다. 하지만 현재까지 대부분의 연구는 최종 결과물이 C 언어 형태로 나오게 되어 있다. 즉 MPSoC 환경을 위한 컴파일러가 따로 제작되어야 하고 이 점은 다양한 이종 MPSoC 환경이 존재한다는 점에서 컴파일러 제작에 많은 부담이 발생한다. 본 논문 본인이 이전에 연구했던 MPSoC 프로그래밍 플랫폼과 플랫폼에서 사용되는 입력 정보의 형태를 설명한다. 그리고 입력정보 형태를 변형하여 재겨냥성(retargetable) 컴파일러와 연동이 가능하게 하여 최종 결과물을 바이너리 형태로 생성할 수 있도록 한다.

• Journal of Animal Science and Technology
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• 제65권5호
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• pp.1105-1109
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• 2023

Pedi coccus acidilactici CACC 537 was isolated from canine feces and reported to have probiotic properties. We aimed to characterize the potential probiotic properties of this strain by functional genomic analysis. Complete genome sequencing of P. acidilactici CACC 537 was performed using a PacBio RSII and Illumina platform, and contained one circular chromosome (2.0 Mb) with a 42% G + C content. The sequences were annotation revealed 1,897 protein-coding sequences, 15 rRNAs, and 56 tRNAs. It was determined that P. acidilactici CACC 537 genome carries genes known to be involved in the immune system, defense mechanisms, restriction-modification (R-M), and the CRISPR system. CACC 537 was shown to be beneficial in preventing pathogen infection during the fermentation process, help host immunity, and maintain intestinal health. These results provide for a comprehensive understanding of P. acidilactici and the development of industrial probiotic feed additives that can help improve host immunity and intestinal health.

• 한국의학물리학회지:의학물리
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• 제25권4호
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• pp.242-247
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• 2014

호흡연동방사선치료(respiratory-gated radiation therapy)법을 적용한 세기조절방사선치료(intensity-modulated radiation therapy, IMRT) 시 환자의 호흡에 의한 장기 움직임 크기에 따른 계산된 선량분포와 측정된 선량분포의 차이를 분석하고자 한다. 치료를 완료한 폐암과 간암 환자 4명을 선택하였다. 한 환자당 5개의 조사면 총 20개의 조사면을 갠트리 각도를 모두 $0^{\circ}$로 변경하여 치료계획시스템(Eclipse Ver. 8.1, Varian Medical Systems, Inc., USA)으로 다시 계산하였다. 치료계획과 동일한 조건으로 각 IMRT 조사면을 2차원 이온전리함배열(MatriXX, IBA Dosimetry, Germany)을 자체 제작한 호흡모 플랫폼(respiratory simulating platform)위에 놓고 0, 1.0, 2.0, 및 3.0 cm 씩 호흡 움직임을 모사하여 일반적으로 치료에 사용되는 연동창 범위인 30~70% 위상을 선택하여 호흡연동방사선치료법으로 조사하여 선량분포를 측하였다. 계산된 선량분포와 측정된 선량분포의 2차원적 비교를 위해 소프트웨어(Omni-pro I'mRT, IBA Dosimetry, Germany)를 이용하여 3 mm/3%의 기준으로 감마 지표(gamma index)로 비교하였다. 움직임이 없을 때 감마 지표의 합격률이 평균 98.63% 였으며, 움직임을 1.0, 2.0, 3.0 cm으로 모사할 경우 합격률이 각각 평균 98.59%, 97.82%, 95.84%로 낮아졌다. 따라서 실제 환자에 대해 호흡연동방사선치료법을 적용한 세기조절방사선치료 시 병소의 움직임이 2 cm가 넘을 경우 ITV (internal target volume) 여유분을 크게 설정하거나 연동창을 좁게 선택하여야한다.

• 한국항행학회논문지
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• 제16권1호
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• pp.158-162
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• 2012

본 논문에서는 2.4GHz 대역에서 적용 가능한 무선 LAN용 모뎀을 설계 제안하였으며, 실제 PCB로 제작되어 데이터 송수신을 확인하였다. 본 논문에서 제안하고 있는 모뎀의 경우, 메인 프로그램을 처리하기 위해 기저대역처리용 프로세서는 처리속도, 동작전압과 신뢰성을 고려하여 현재 Wi-Fi모뎀에 많이 적용되고 있는 Ralink사의 RT2870을 사용하였다. RT2870은 현재 무선 LAN의 표준을 완벽히 지원하며, 다양한 변조방식을 지원하고 있으며, 2.4GHz와 5GHz대역을 모두 지원하는 칩이다. 또한 본 논문에서는 출력된 변조신호를 2.4GHz대역의 무선으로 전송하기 위하여 RF 처리용 칩인 RT2850을 적용하였으며, 40MHz 대역을 사용하여 2.422~2.462GHz의 무선 대역을 점유하도록 설계하였다. 제안된 모뎀은 저렴한 비용으로 향후 2.4GHz 대역의 무선인터넷 모뎀으로의 사용이 가능하며, 본 설계를 바탕으로 Wi-Fi기반의 개인통신기기 또는 무선 기반 POS시스템 개발에 적극 활용이 가능하다. 특히, 안드로이드 기반 개인용 무선단말기의 모뎀으로 적용이 가능하며 이를 이용하여 다양한 제품으로의 확대가 가능할 것으로 기대된다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2021년도 학술발표회
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• pp.161-161
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• 2021

본 연구에서는 금강 상류의 용담댐 유역(930.0 km²)을 대상으로 Sentinel-1 SAR(Synthetic Aperture Radar) 및 Sentinel-2 MultiSpectral Instrument(MSI) 위성영상을 활용한 토양수분 산출연구를 수행하였다. 연구에 사용된 자료는 10 m 해상도의 Sentinel-1 IW(Interferometric Wide swath) mode GRD(Ground Range Detected) product의 VV(Vertical transmit-Vertical receive) 및 VH(Vertical transmit-Horizontal receive) 편파자료와 Sentinel-2 Level-2A Bottom of Atmosphere(BOA) reflectance 자료를 2019년에 대해 각 6일 및 5일 간격으로 구축하였다. 위성영상의 Image processing은 SNAP(SentiNel Application Platform)을 활용하여 Sentinel-1 영상의 편파 별(VV, VH) 후방산란계수와 Sentinel-2의 적색(Band-4) 및 근적외(Band-8) 영상을 생성하였다. 토양수분 산출 모형은 다중선형회귀모형(Multiple Linear Regression Model)을 활용하였으며, 각 지점에 해당하는 토양 속성별로 모형을 생성하였다. 모형의 입력자료는 Sentinel-1 위성의 편파별 후방산란계수, Sentinel-1 위성에서 산출된 식생지수 RVI(Radar Vegetation Index)와 Sentinel-2 위성에서 산출된 NDVI(Normalized Difference Vegetation Index)를 활용하여 식생의 영향을 반영하고자 하였다. 모의 된 토양수분을 검증하기 위해 6개 지점의 TDR(Time Domain Reflectometry) 기반 실측 토양수분 자료를 수집하고, 상관계수(Correlation Coefficient, R), 평균제곱근오차(Root Mean Square Error, RMSE) 및 IOA(Index of Agreement)를 활용하여 전체 기간 및 계절별로 나누어 검증할 예정이다.

• International Journal of Advanced Culture Technology
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• 제7권4호
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• pp.313-320
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• 2019

Nowadays, as the availability of tiny, low-cost microcomputer increases at a high level, mobile robots are experiencing remarkable enhancements in hardware design, software performance, and connectivity advancements. In order to control Turtlebot 2, several algorithms have been developed using the Robot Operating System(ROS). However, ROS requires to be run on a high-cost computer which increases the hardware cost and the power consumption to the robot. Therefore, design an algorithm based on low-cost hardware is the most innovative way to reduce the unnecessary costs of the hardware, to increase the performance, and to decrease the power consumed by the computer on the robot. In this paper, we present a path-finding algorithm for TurtleBot 2 based on low-cost hardware. We implemented the algorithm using Raspberry pi, Windows 10 IoT core, and RPLIDAR A2. Firstly, we used Raspberry pi as the alternative to the computer employed to handle ROS and to control the robot. Raspberry pi has the advantages of reducing the hardware cost and the energy consumed by the computer on the robot. Secondly, using RPLIDAR A2 and Windows 10 IoT core which is running on Raspberry pi, we implemented the path-finding algorithm which allows TurtleBot 2 to navigate from the starting point to the destination using the map of the area. In addition, we used C# and Universal Windows Platform to implement the proposed algorithm.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.437-442
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• 2015

Aim: To establish a pancreatic cancer stem cell model using human pancreatic cancer cells in nude mice to provide a platform for pancreatic cancer stem cell research. Materials and Methods: To establish pancreatic cancer xenografts using human pancreatic cancer cell line SW1990, nude mice were randomly divided into control and gemcitabine groups. When the tumor grew to a volume of $125mm^3$, they treated with gemcitabine at a dose of 50mg/kg by intraperitoneal injection of 0.2ml in the gemcitabine group, while the mice in control group were treated with the same volume of normal saline. Gemcitabine was given 2 times a week for 3 times. When the model was established, the proliferation of pancreatic cancer stem cells was observed by clone formation assay, and the protein and/or mRNA expression of pancreatic stem cell surface markers including CD24, CD44, CD133, ALDH, transcription factors containing Oct-4, Sox-2, Nanog and Gli, the key nuclear transcription factor in Sonic Hedgehog signaling pathway was detected by Western blot and/or RT-PCR to verify the reliability of this model. Results: This model is feasible and safe. During the establishment, no mice died and the weight of nude mice maintained above 16.5g. The clone forming ability in gemcitabine group was stronger than that of the control group (p<0.01). In gemcitabine group, the protein expression of pancreatic cancer stem cell surface markers including CD44, and ALDH was up-regulated, the protein and mRNA expression of nuclear transcription factor including Oct-4, Sox-2 and Nanog was also significantly increased (P<0.01). In addition, the protein expression of key nuclear transcription factor in Sonic Hedgehog signaling pathway, Gli-1, was significantly enhanced (p<0.01). Conclusions: The pancreatic cancer stem cell model was successfully established using human pancreatic cancer cell line SW1990 in nude mice. Gemcitabine could enrich pancreatic cancer stem cells, simultaneously accompanied by the activation of Sonic Hedgehog signaling pathway.

• The Plant Pathology Journal
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• 제31권2호
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• pp.108-114
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• 2015

Curvularia lunata is an important maize foliar fungal pathogen that distributes widely in maize growing area in China, and several key pathogenic factors have been isolated. An yeast two-hybrid (Y2H) library is a very useful platform to further unravel novel pathogenic factors in C. lunata. To construct a high-quality full length-expression cDNA library from the C. lunata for application to pathogenesis-related protein-protein interaction screening, total RNA was extracted. The SMART (Switching Mechanism At 5' end of the RNA Transcript) technique was used for cDNA synthesis. Double-stranded cDNA was ligated into the pGADT7-Rec vector with Herring Testes Carrier DNA using homologous recombination method. The ligation mixture was transformed into competent yeast AH109 cells to construct the primary cDNA library. Eventually, a high qualitative library was successfully established according to an evaluation on quality. The transformation efficiency was about $6.39{\times}10^5$ transformants/$3{\mu}g$ pGADT7-Rec. The titer of the primary cDNA library was $2.5{\times}10^8cfu/mL$. The numbers for the cDNA library was $2.46{\times}10^5$. Randomly picked clones show that the recombination rate was 88.24%. Gel electrophoresis results indicated that the fragments ranged from 0.4 kb to 3.0 kb. Melanin synthesis protein Brn1 (1,3,8-hydroxynaphthalene reductase) was used as a "bait" to test the sufficiency of the Y2H library. As a result, a cDNA clone encoding VelB protein that was known to be involved in the regulation of diverse cellular processes, including control of secondary metabolism containing melanin and toxin production in many filamentous fungi was identified. Further study on the exact role of the VelB gene is underway.

• 한국운동역학회지
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• 제14권2호
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• pp.85-103
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• 2004

This study was conducted to determine what effects would the midsole hardness of running shoes have on shoe flex angle and maximum propulsive force. Furthermore, the relationship between the shoes flex angle and maximum propulsive force was elucidated in order to provide basic data for developing running shoes to improve sports performances and prevent injuries. The subjects employed in the study were 10 college students majoring in physical education who did not have lower limbs injuries for the last one year and whose running pattern was rearfoot strike pattern of normal foot. The shoes used in this study had 3different hardness, shore A 40(soft), 50(medium) and 60(hard). The subjects were asked to run at a speed of $4{\pm}0.08m/sec$, and their movements were videotaped with 2 S-VHS video-cameras and measured with a force platform. And the following results were obtained after analyzing and comparing the variables. 1. Although the minimum angle of shoes flex angle was estimated to appear at SFA4, it appeared at SFA2 except in those shoes with the hardness of 40. 2. The minimum angle of shoes flex angle was $145.1^{\circ}$ with barefoot. Among the shoes with different hardness, it was the smallest when the hardness was 50 at $149.9^{\circ}$. The time to the minimum angle was 70.7% of the total ground contact time. 3. Maximum propulsive force according to midsole hardness was the largest when the hardness was 50 at $1913.9{\pm}184.3N$. There was a low correlation between maximum propulsive force and shoes flex angle.

• Journal of Korean Neurosurgical Society
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• 제65권4호
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• pp.572-581
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• 2022

Objective : Compared to microscopes, exoscopes have advantages in field-depth, ergonomics, and educational value. Exoscopes are especially well-poised for adaptation into fluorescence-guided surgery (FGS) due to their excitation source, light path, and image processing capabilities. We evaluated the feasibility of near-infrared FGS using a 3-dimensional (3D), 4 K exoscope with near-infrared fluorescence imaging capability. We then compared it to the most sensitive, commercially-available near-infrared exoscope system (3D and 960 p). In-vitro and intraoperative comparisons were performed. Methods : Serial dilutions of indocyanine-green (1-2000 ㎍/mL) were imaged with the 3D, 4 K Olympus Orbeye (system 1) and the 3D, 960 p VisionSense Iridium (system 2). Near-infrared sensitivity was calculated using signal-to-background ratios (SBRs). In addition, three patients with brain tumors were administered indocyanine-green and imaged with system 1, with two also imaged with system 2 for comparison. Results : Systems 1 and 2 detected near-infrared fluorescence from indocyanine green concentrations of >250 ㎍/L and >31.3 ㎍/L, respectively. Intraoperatively, system 1 visualized strong near-infrared fluorescence from two, strongly gadolinium-enhancing meningiomas (SBR=2.4, 1.7). The high-resolution, bright images were sufficient for the surgeon to appreciate the underlying anatomy in the near-infrared mode. However, system 1 was not able to visualize fluorescence from a weakly-enhancing intraparenchymal metastasis. In contrast, system 2 successfully visualized both the meningioma and the metastasis but lacked high resolution stereopsis. Conclusion : Three-dimensional exoscope systems provide an alternative visualization platform for both standard microsurgery and near-infrared fluorescent guided surgery. However, when tumor fluorescence is weak (i.e., low fluorophore uptake, deep tumors), highly sensitive near-infrared visualization systems may be required.