• Title/Summary/Keyword: M1 M2

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Chlorophyll-a Concentrations of Microplankton and Nannoplankton in the Coastal Seas of Korea in Fall (가을철 한국주변해역의 Microplankton 및 Nannoplankton의 클로로필함량과 분포)

  • CHO Chang-Hwan
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.18 no.1
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    • pp.63-66
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    • 1985
  • Phytoplankton (microplankton and nannoplankton) biomass as chlorophyll-a concentrations ana ratios of nannoplanktons ($size<60{\mu}m$) to total phytoplanktons ($size<300{\mu}m$) were measured in the coastal waters of Korea in fall, 1983. Chlorophyll-a concentrations of total phytoplankton ranged from 0.202 to 1.350 $mg/m^3$ with a mean and standard deviation, $0.597{\pm}0.287\;mg/m^3$, Chlorophyll-a concentrations of the nannoplankton ranged from 0.100 to $0.855\;mg/m^3$ with a mean and standard deviation, $0.372{\pm}0.201\;mg/m^3$, and it accounted for 25.4 to $83.3\%$ with an average $62.2\%$ to total phytoplankton biomass as chlorophyll-a concentrations. The amounts of chlorophyll-a concentrations of total phytoplankton in the water column below the surface area of $1m^2$ varied from 16.12 to $17.67\;mg/m^2$ with a mean $17.01\;mg/m^2$.

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The Significance of Plasma Urokinase-type Plasminogen Activator and Type 1 Plasminogen Activator Inhibitor in Lung Cancer (폐암에서 혈장 Urokinase-Type Plasminogen Activator 및 Type 1 Plasminogen Activator Inhibitor의 의의)

  • Park, Kwang-Joo;Kim, Hyung-Jung;Ahn, Chul-Min;Lee, Doo-Yun;Chang, Joon;Kim, Sung-Kyu;Lee, Won-Young
    • Tuberculosis and Respiratory Diseases
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    • v.44 no.3
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    • pp.516-524
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    • 1997
  • Background : Cancer invasion and metastasis require the dissolution of the extracellular matrix in which several proteolytic enzymes are involved. One of these enzymes is the urokinase-type plasminogen activator(u-PA), and plasminogen activator inhibitors(PAI-1, PAI-2) also have a possible role in cancer invasion and metastasis by protection of cancer itself from proteolysis by u-PA. It has been reported that the levels of u-PA and plasminogen activator inhibitors in various cancer tissues are significantly higher than those in normal tissues and have significant correlations with tumor size and lymph node involvement. Here, we measured the concentration of plasma u-PA and PAI-1 antigens in the patients with lung cancer and compared the concentration of them with histologic types and staging parameters. Methods : We measured the concentration of plasma u-PA and PAI-1 antigens using commercial ELISA kit in 37 lung cancer patients, 21 benign lung disease patients and 24 age-matched healthy controls, and we compared the concentration of them with histologic types and staging parameters in lung cancer patients. Results : The concentration of u-PA was $1.0{\pm}0.3ng/mL$ in controls, $1.0{\pm}0.3ng/mL$ in benign lung disease patients and $0.9{\pm}0.3ng/mL$ in lung cancer patients. The concentration of PAI-1 was $14.2{\pm}6.7ng/mL$ in controls, $14.9{\pm}6.3ng/mL$ in benign lung disease patients, and $22.1{\pm}9.8ng/mL$ in lung cancer patients. The concentration of PAI-1 in lung cancer patients was higher than those of benign lung disease patients and controls. The concentration of u-PA was $0.7{\pm}0.4ng/mL$ in squamous cell carcinoma, $0.8{\pm}0.3ng/mL$ in adenocarcinoma, 0.9ng/mL in large cell carcinoma, and $1.1{\pm}0.7ng/mL$ in small cell carcinoma. The concentration of PAI-1 was $22.3{\pm}7.2ng/mL$ in squamous cell carcinoma, $22.6{\pm}9.9ng/mL$ in adenocarcinoma, 42 ng/mL in large cell carcinoma, and $16.0{\pm}14.2ng/mL$ in small cell carcinoma. The concentration of u-PA was 0.74ng/mL in stage I, $1.2{\pm}0.6ng/mL$ in stage II, $0.7{\pm}0.4ng/mL$ in stage IIIA, $0.7{\pm}0.4ng/mL$ in stage IIIB, and $0.7{\pm}0.3ng/mL$ in stage IV. The concentration of PAI-1 was 21.8ng/mL in stage I, $22.7{\pm}8.7ng/mL$ in stage II, $18.4{\pm}4.9ng/mL$ in stage IIIA, $25.3{\pm}9.0ng/mL$ in stage IIIB, and $21.5{\pm}10.8ng/mL$ in stage IV. When we divided T stage into T1-3 and T4, the concentration of u-PA was $0.8{\pm}0.4ng/mL$ in T1-3 and $0.7{\pm}0.4ng/mL$ in T4, and the concentration of PAI-1 was $17.9{\pm}5.6ng/mL$ in T1-3 and $26.1{\pm}9.1ng/mL$ in T4. The concentration of PAI-1 in T4 was significantly higher than that in T1-3. The concentration of u-PA was $0.8{\pm}0.4ng/mL$ in M0 and $0.7{\pm}0.3ng/mL$ in M1, and the concentration of PAI-1 was $23.6{\pm}8.3ng/mL$ in M0 and $21.5{\pm}10.8ng/mL$ in M1. Conclusions : The plasma levels of PAI-1 in lung cancer were higher than benign lung disease and controls, and the plasma levels of PAI-1 in T4 were significantly higher than T1-3. These findings suggest involvement of PAI-1 with local invasion of lung cancer, but it should be confirmed by the data on comparison with pathological staging and tissue level in lung cancer.

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Mutual Authentication and Key Establishment Protocol to Implement Secure M2M Communication Environments (안전한 M2M 통신 구축을 위한 상호인증 및 키 교환 프로토콜)

  • Eun, Sun-Ki;Jeon, Seo-Kwan;Ahn, Jae-Young;Oh, Soo-Hyun
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.20 no.1
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    • pp.73-83
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    • 2010
  • Recently, as IT technologies developed, communication technologies of a various forms that satisfied convenience of user are being researched. Among various research, unlike traditional forms of communication, M2M communication is getting attention that without any control or involvement of people to establish communication between devices. However, the M2M communication could more easily be exposed to many security problems such as data exposure, data theft, unauthorized change and delete and privacy. Therefore, in this paper, we derive security requirements and propose the M2M communication architecture that provide a secure M2M communication environment. Also, we propose a secure mutual authentication and key establishment protocol between a M2M device or gateway domain and a M2M network domain. The proposed protocol is secure against replay attack, impersonation attack and protect a user privacy and tracing.

Analysis of Patient Effective Dose in PET/CT; Using CT Dosimetry Programs (CT 선량 측정 프로그램을 이용한 PET/CT 검사 환자의 예측 유효 선량의 분석)

  • Kim, Jung-Sun;Jung, Woo-Young;Park, Seung-Yong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.14 no.2
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    • pp.77-82
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    • 2010
  • Purpose: As PET/CT come into wide use, it caused increasing of expose in clinical use. Therefore, Korea Food and Drug Administration issued Patient DRL (Diagnostic Reference Level) in CT scan. In this study, to build the basis of patient dose reduction, we analyzed effective dose in transmission scan with CT scan. Materials and Methods: From February, 2010 to March 180 patients (age: $55{\pm}16$, weight: $61.0{\pm}10.4$ kg) who examined $^{18}F$-FDG PET/CT in Asan Medical Center. Biograph Truepoint 40 (SIEMENS, GERMANY), Biograph Sensation 16 (SIEMENS, GERMANY) and Discovery STe8 (GE healthcare, USA) were used in this study. Per each male and female average of 30 patients doses were analyzed by one. Automatic exposure control system for controlling the dose can affect the largest by a patient's body weight less than 50 kg, 50-60 kg less, 60 kg more than the average of the three groups were divided doses. We compared that measured value of CT-expo v1.7 and ImPACT v1.0. The relationship between body weight and the effective dose were analyzed. Results: When using CT-Expo V1.7, effective dose with BIO40, BIO16 and DSTe8 respectably were $6.46{\pm}1.18$ mSv, $9.36{\pm}1.96 $mSv and $9.36{\pm}1.96$ mSv for 30 male patients respectably $6.29{\pm}0.97$ mSv, $10.02{\pm}2.42$ mSv and $9.05{\pm}2.27$ mSv for 30 female patients respectably. When using ImPACT v1.0, effective dose with BIO40, BIO16 and DSTe8 respectably were $6.54{\pm}1.21$ mSv, $8.36{\pm}1.69$ mSv and $9.74{\pm}2.55$Sv for 30 male patients respectably $5.87{\pm}1.09$ mSv, $8.43{\pm}1.89$ mSv and $9.19{\pm}2.29$ mSv for female patients respectably. When divided three groups which were under 50 kg, 50~60 kg and over 60 kg respectably were 6.27 mSv, 7.67 mSv and 9.33 mSv respectably using CT-Expo V1.7, 5.62 mSv, 7.22 mSv and 8.91 mSv respectably using ImPACT v1.0. Weight and the effective dose coefficient analysis showed a very strong positive correlation(r=743, r=0.693). Conclusion: Using such a dose evaluation programs, easier to predict and evaluate the effective dose possible without performing phantom study and such dose evaluation programs could be used to collect basic data for CT dose management.

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Effects of Presoaking Treatments on Emergence of Tea (Camellia sinensis) Seeds (파종전처리가 차나무 종자의 출아에 미치는 영향)

  • Shim, Doobo;Jeon, Seung-Ho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.65 no.2
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    • pp.156-160
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    • 2020
  • Emergence and early growth changes of stratification condition of tea (Camellia sinensis) seeds were investigated in 7 treatments (control, pH 4, pH 10, 70% ethanol (EtOH), 10 mM H2O2, 100 mM H2O2, and physical shock (5.9 J)). Ethanol treatment was toxic and did not induce emergence. The emergence rate was 36.7% in the control, 26.7% under pH 10, 46.7% under pH 4, 48.3% under physical shock, 51.7% under 10 mM H2O2, and 65.0% under 100 mM H2O2 treatments. It was higher by approximately 178% in the H2O2 treatment as compared to the control. Plant height was 6.5 cm in the control, 6.6 cm under pH 10, 7.6 cm under pH 4, 7.8 cm under physical shock, 8.3 cm under 10 mM H2O2, and 9.1 cm under 100 mM H2O2 treatments. Leaf length and leaf width were also higher under the H2O2 treatment. Therefore, hydrogen peroxide treatment induced emergence and increased the uniformity of early growth.

1-(2-) Prime Ideals in Semirings

  • Nandakumar, Pandarinathan
    • Kyungpook Mathematical Journal
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    • v.50 no.1
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    • pp.117-122
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    • 2010
  • In this paper, we introduce the concepts of 1-prime ideals and 2-prime ideals in semirings. We have also introduced $m_1$-system and $m_2$-system in semiring. We have shown that if Q is an ideal in the semiring R and if M is an $m_2$-system of R such that $\overline{Q}{\bigcap}M={\emptyset}$ then there exists as 2-prime ideal P of R such that Q $\subseteq$ P with $P{\bigcap}M={\emptyset}$.

Direct Bonding of Si II 1.3$\mu\textrm{m}$-SiO$_2$/1.3$\mu\textrm{m}$-SiO$_2$ II SOI substrates prepared by FLA method (선형접합기를 이용한 Si II 1.3$\mu\textrm{m}$-SiO$_2$/1.3$\mu\textrm{m}$-SiO$_2$ II SOI 기판의 직접접합)

  • 송오성;이영민;이상현;이진우;강춘식
    • Journal of the Korean institute of surface engineering
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    • v.34 no.1
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    • pp.33-38
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    • 2001
  • 10cm-diameter Si(100)∥$1.3\mu\textrm{m}$-X$1.3_2$X$1.3\mu\textrm{m}$-$SiO_2$∥Si(100) afers were prepared using a fast linear annealing (FLA) equipment. 1.3$\mu\textrm{m}$-thick $SiO_2$ films were grown by dry oxidation process. After cleaning and premating the wafers in a class 100 clean room, they were heat treated using with the FLA and conventional electric furnace. Bonded area and bond strength of wafer pairs were measured using a infrared (IR) camera and razor blade crack opening method, respectively. It was confinmed that the bonded area by FLA was around 99% and the bond strength value reached 2172mJ/$\m^2$, which is equivalent to theoritical bond strength. Our result implies that thick $SiO_2$ SOI may be prepared more easily by using $SiO_2$$SiO_2$ bonding interfaces then those of Si/$SiO_2$'s.

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The Action of ATP on Phospholipase $A_2$Activation in C6 Cells (C6세포에서 phospholipase $A_2$활성에 대한 ATP의 작용)

  • 심상수;김명준;윤신희;김창종;조양혁
    • YAKHAK HOEJI
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    • v.45 no.4
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    • pp.413-418
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    • 2001
  • To investigate action of ATP on ischemia-induced brain injury, we measured phospholipase $A_2$activity and nitric oxide (NO) production in C6 cells. ATP alone did not have any influence on phospholipase $A_2$activity but increased NO production. Glutamate (1 mM) significantly increased phospholipase $A_2$activity whereas did not increased NO production. ATP significantly inhibited phospholipase $A_2$activation induced by 0.1 $\mu$M A23187, 1 mM glutamate and 1 mM $H_2O$$_2$, but did not inhibited 1 $\mu$M PMA-induced phospholipase $A_2$activation. From the above results, it is suggested that the action of ATP in C6 cells has dual actions, such as the inhibition of agonist-induced phospholipase $A_2$activation and the increase of NO production.

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Hydrothermal Synthesis of PZT Powders. (수열법에 의한 PZT분말 합성 연구)

  • 최승도;박병규
    • Korean Journal of Crystallography
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    • v.8 no.2
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    • pp.97-104
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    • 1997
  • Hydrothermal synthesis of PbZ1-xTixO3 has been investigated. Syntheses were performed using lead acetate triphdrate as Pb source, Ti/Zr gel by hydrolizing Ti-isopropoxide as Tiand Zr source and Zr-propoxide and KOH (0.5m, 1m, 2m) as mineralizer. The hydrothermal synthesis has been examined at 140℃, 150℃ and 160℃. Synthesized PZT powders showed a rectangular shape and were agglomerate. At 1m and 2m KOH concentrations PZT powders were synthesized the respective time of 8 hrs and 1hr but at 0.5m KOH concentration phase pure PZT powders were not synthesized for 5days reaction. At the conditions of low temperature and low KOH concentration unreacted Ti/Zr gel remained although synthesized powders were almost PZT. The size of PZT powders increased with KOH concentrations. PbO solid solutions were formed as intermediate phases and these were classified to PbO-10%TiO2 solid solution and PbO-3% TiO-3% TiO2 solid solution.

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Effects of Taraxacum mongolicum Extract on Blood Glucose Levels and Lipid Profiles in Streptozotocin-Induced Diabetic Rats

  • Hye Kyoung Han;Eun Young Choi
    • The Korean Journal of Food And Nutrition
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    • v.36 no.1
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    • pp.50-57
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    • 2023
  • This study was designed to evaluate antihyperglycemic and antihyperlipidemic effects of ethanol extracts of Taraxacum mongolicum(T.m.) on streptozotocin (STZ)-induced diabetic rats. Sprague-Dawley rats were randomly assigned to five groups: normal (NC), STZ-control (DC), and three experimental groups. Diabetes was induced in Sprague-Dawley rats with a single intravenous injection [45 mg/kg body weight (b.w.)] of STZ. An ethanol extract of T.m. was orally given to diabetic rats for 14 days. Three experimental groups were additionally treated with T.m. extract at doses of 1 g/kg b.w./day for T.m.-1, 2 g/kg b.w./day for T.m.-2, and 3 g/kg b.w./day for T.m.-3. Oral administration of T.m.-2 significantly increased their body weights. T.m.-1 and T.m.-2 significantly decreased aspartate aminotransferase (AST) levels than DC. T.m.-1 and T.m.-2 group significantly decreased blood glucose levels. Total cholesterol, triglycerides, and free fatty acids were significantly decreased whereas high-density lipoprotein cholesterol was significantly increased in groups treated with T.m. extract than those in the DC group. These results support the fact that administration of T.m. extract can reduce hyperglycemia and hyperlipidemia risk in diabetic rats.