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THE APPLICATION OF STOCHASTIC ANALYSIS TO POPULATION GENETICS MODEL

  • Choi, Won
    • Journal of applied mathematics & informatics
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    • v.23 no.1_2
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    • pp.455-460
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    • 2007
  • In allelic model $X=(x_1,\;x_2,\;{\cdots},\;x_d)$, $$M_f(t)=f(p(t))-{\int}_0^t\;Lf(p(t))ds$$ is a P-martingale for diffusion operator L under the certain conditions. In this note, we try to apply diffusion processes for countable-allelic model in population genetic model and we can define a new diffusion operator $L^*$. Since the martingale problem for this operator $L^*$ is related to diffusion processes, we can define a integral which is combined with operator $L^*$ and a bilinar form $<{\cdot},{\cdot}>$. We can find properties for this integral using maximum principle.

Priming Conditions to Improve Germination of Salvia (Salvia splendens F.) Seeds (샐비아(Salvia splendens F.) 종자의 발아촉진을 위한 Priming 조건에 관한 연구)

  • Jeong, Yeon-Ok;Kang, Seong-Mo;Cho, Jeoung-Lai
    • Horticultural Science & Technology
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    • v.18 no.2
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    • pp.98-102
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    • 2000
  • This experiment was conducted to determine the effect of chemicals and their concentrations, priming temperature and duration, and different germination temperature on germinability of salvia seeds. The highest percentage of germination was obtained with 50 or 100 mM $KH_2PO_4$, or with -0.50 or -0.75 MPa PEG 8000. When number of days to attain 50% of the final germination percentage (T50) and mean number of days to germination (MDG) were taken into account, 50 mM $KH_2PO_4$ or -0.50 MPa PEG was most effective for early germination. No seeds germinated when primed in $K_3PO_4$ or NaOH solution. Priming the seeds at $20^{\circ}C$ was better than priming at $15^{\circ}C$ or $25^{\circ}C$. Priming at $20^{\circ}C$ for 4 or 6 days reduced the MDG by 2.3 days compared with nonprimed seeds. Seeds primed with -0.50 MPa PEG at $20^{\circ}C$ showed a high germination percentage with reduced T50 and MDG. When seeds were primed in a mixture of -0.50 MPa PEG and 50 mM $KH_2PO_4$ solution and germinated at $30^{\circ}C$ or $35^{\circ}C$, percent germination was lower than nonprimed seeds. However, the combined treatment retained the priming effect for reducing T50 and MDG.

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Immunological Characterization of Full and Truncated Recombinant Clones of ompH(D:4) Obtained from Pasteurella multocida (D:4) in Korea

  • Kim, Young-Hwan;Cheong, Ki-Young;Shin, Woo-Seok;Hong, Sung-Youl;Woo, Hee-Jong;Kwon, Moo-Sik
    • Journal of Microbiology and Biotechnology
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    • v.16 no.10
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    • pp.1529-1536
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    • 2006
  • We cloned a gene of ompH(D:4) from pigs infected with P. multocida D:4 in Korea [16]. The gene is composed of 1,026 nucleotides coding 342 amino acids (aa) with a signal peptide of 20 aa (GenBank accession number AY603962). In this study, we analyzed the ability of the ompH(D:4) to induce protective immunity against a wild-type challenge in mice. To determine appropriate epitope(s) of the gene, one full and three different types of truncated genes of the ompH(D:4) were constructed by PCR using pET32a or pRSET B as vectors. They were named ompH(D:4)-F (1,026 bp [1-1026] encoding 342 aa), ompH(D:4)-t1 (693 bp [55-747] encoding 231 aa), ompH(D:4)-t2 (561 bp [187-747] encoding 187 aa), and ompH(D:4)-t3 (540 bp [487-1026] encoding 180 aa), respectively. The genes were successfully expressed in Escherichia coli BL21(DE3). Their gene products, polypeptides, OmpH(D:4)-F, -t1, -t2, and -t3, were purified individually using nickel-nitrilotriacetic acid (Ni-NTA) affinity column chromatography. Their $M_rs$ were determined to be 54.6, 29, 24, and 23.2 kDa, respectively, using SDS-PAGE. Antisera against the four kinds of polypeptides were generated in mice for protective immunity analyses. Some $50{\mu}g$ of the four kinds of polypeptides were individually provided intraperitoneally with mice (n=20) as immunogens. The titer of post-immunized antiserum revealed that it grew remarkably compared with pre-antiserum. The lethal dose of the wild-type pathogen was determined at $10{\mu}l$ of live P. multocida D:4 through direct intraperitoneal (IP) injection, into post-immune mice (n=5, three times). Some thirty days later, the lethal dose ($10{\mu}l$) of live pathogen was challenged into the immunized mouse groups [OmpH(D:4)-F, -t1, -t2, and -t3; n=20 each, two times] as well as positive and negative control groups. As compared within samples, the OmpH(D:4)-F-immunized groups showed lower immune ability than the OmpH(D:4)-t1, -t2, and -t3. The results show that the truncated-OmpH(D:4)-t1, -t2, and -t3 can be used for an effective vaccine candidate against swine atrophic rhinitis caused by pathogenic P. multocida (D:4) isolated in Korea.

Filtering Rate with Effect of Water Temperature and Size of Two Farming Ascidians Styela clava and S. plicata, and a Farming Mussel Mytilus edulis (수온과 개체크기에 따른 양식산 미더덕, 흰멍게, 진주담치의 여수율)

  • KIM Yong Sool;Moon Tae Seok
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.2
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    • pp.272-277
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    • 1998
  • Filtering rates of two farming ascidians Styela clava and S. plicata, and of a farming mussel Mytilus edulis were experimentally investigated with reference to effects of water temperature and size. Absorptiometric determinations of filtering rates were carried out in a closed system with experimental animals being decreased indicate dyes neutral red. Optical density (OD) of 440 nm in path length 22 mm cell used as the indication of food particles absorption was appeared directly in proportion with the concentration of neutral red dyes. The filtering rate F is calculated by Kim's equation $F\;=\;V(1-e^{-z})$, where V is the water volume ($\ell$) in the experimental jar, and Z is the decreasing coefficient of OD as meaning of instantaneous removal speed as In $C_t\;=\;In\;C_{o}-Z{\cdot}t$, in this formula $C_t$ is OD at the time t. Filtering rate of S. clava increased as exponential function with increasing temperature while not over critical limit, and the critical temperature for filtering rate was assumed to be between $28^{\circ}C$ and $29^{\circ}C$. In case of S. plicata, the critical temperature was to be below $13^{\circ}C$, and through the temperature range $15\~25^{\circ}C$ appeared a little difference in level even though with significant. M. edulis was not appear any significant effects by water temperature less than $29^{\circ}C$. The model formula derived from the results is as below, where F is filtering rate (${\ell}/hr/animal$), T is water temperature ($^{\circ}C$), and DW is dry meat weight (g) of experimental animal. $$S.\;Clava;\;F\;=\;e xp\;(0.119\;T-4.540)\;(DW)^{0.6745},\;T<29^{\circ}C$$) $$S.\;plicata;\;F\;=\;e xp\;(A_t)\;(DW)^{0.5675},\;(13^{\circ}C $$[A_t =-8.56+0.6805\;T-0.0153\;T^2]$$ $$M.\;edulis;\;F\;=\;0.3844\;(DW)^{0.4952},\;<29^{\circ}C$$)

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Studies on the Isolation, Purification and Characterization of a Cx Enzyme Produced by Pyricularia oryzae, $C-7^{+t}$ (도열병균에서 추출한 Cx효소의 순화 및 특성에 관한 연구)

  • Kim, Sang-Ho;Kim, W.S.
    • The Korean Journal of Mycology
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    • v.10 no.2
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    • pp.67-73
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    • 1982
  • The $(NH_4)_2\;SO_4$ (70%) treated crude enzymes from the culture filtrates of the$C-7^{+t}$ strain of Pyricularia oryzae which was grown on 2% CMC (carboxymethyl cellulose) for 8 days at $28^{\circ}C$ were chromatographied on Sephadex G-150 and DEAE-Sephadex A-25 columns. From the chromatography, three fractions of CMCase$(C_x)$ was examined using Na-CMC as substrate. The $C_x$ enzyme activity was optimal at pH 6.0 and $40^{\circ}C$, stable up to $40^{\circ}C$. The values of Km and Vmax of the enzyme were $2.8{\times}10\;mM$ and 5.9m moles/hour, respectively. The molecular weight determined by Sephadex G-150 column chromatography was around 80,000. Approximately sevenfold purified $C_x$ enzyme gave a single protein band on the polyacrylamide gel electrophoresis.

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Simulation-based Yield-per-recruit Analysis of Sandfish Arctoscopus japonicus in the East Sea of Korea Subjected to Natural Mortality Conditions (모의실험을 통한 한국 동해 도루묵(Arctoscopus japonicus)의 자연사망 계수 조건에 따른 가입당 생산 분석)

  • Kyunghwan Lee;Ho Young Soh;Giphil Cho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.56 no.3
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    • pp.331-340
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    • 2023
  • To estimate the biological reference points, suitable for fisheries management of sandfish Arctoscopus japonicas in the East Sea of Korea, we simulated the yield-per-recruit (Y/R) from age 0 to 6 (0-2,555 days). The stimulation was based on two instantaneous natural mortality conditions: size-dependent (Mt, d-1) and constant (Mcons, d-1); Subsequently, the biological reference points of the two mortality conditions was compared. Mt decreased from 0.0075 d-1 to 0.0018 d-1 depending on growth, and Mcons remained constant at 0.0011 d-1 for all ages. Our Y/R model showed that the maximum yield of Mcons was 14 times higher than that of the Mt. The length at first capture to maximize the harvest at the F0.1 points of the two natural mortality conditions was Lc,t=10.2 cm (TL) and Lc,cons=17 cm (TL). We concluded that Mt was more suitable for estimating M than Mcons; this is because Lc,t showed minimal difference from the current fishing regulations (11 cm, TL), and Mt reflected more biological characteristics than Mcons. We suggest that 10.2 cm and 0.8 as the suitable length at first capture and corresponding age, respectively for efficient fisheries management of sandfish.

ON SOLVABILITY OF THE DISSIPATIVE KIRCHHOFF EQUATION WITH NONLINEAR BOUNDARY DAMPING

  • Zhang, Zai-Yun;Huang, Jian-Hua
    • Bulletin of the Korean Mathematical Society
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    • v.51 no.1
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    • pp.189-206
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    • 2014
  • In this paper, we prove the global existence and uniqueness of the dissipative Kirchhoff equation $$u_{tt}-M({\parallel}{\nabla}u{\parallel}^2){\triangle}u+{\alpha}u_t+f(u)=0\;in\;{\Omega}{\times}[0,{\infty}),\\u(x,t)=0\;on\;{\Gamma}_1{\times}[0,{\infty}),\\{\frac{{\partial}u}{\partial{\nu}}}+g(u_t)=0\;on\;{\Gamma}_0{\times}[0,{\infty}),\\u(x,0)=u_0,u_t(x,0)=u_1\;in\;{\Omega}$$ with nonlinear boundary damping by Galerkin approximation benefited from the ideas of Zhang et al. [33]. Furthermore,we overcome some difficulties due to the presence of nonlinear terms $M({\parallel}{\nabla}u{\parallel}^2)$ and $g(u_t)$ by introducing a new variables and we can transform the boundary value problem into an equivalent one with zero initial data by argument of compacity and monotonicity.

Development of Image Post-processing System for the Cerebral Perfusion Information Mapping of MR Image (MR영상의 뇌관류 정보 Mapping을 위한 영상후처리 시스템개발)

  • 이상민;강경훈;장두봉;김광열;김영일;신태민
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.4 no.1
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    • pp.131-138
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    • 2000
  • This paper works on development of an algorithm for mapping of cerebral perfusion parameters using the gamma-variate curve fitting. The signal intensity variate curve according to time measured in each pixel of perfusion MRI is nonlinear, and various hemodynamic parameters are not computed accurately. Levenberg-Marquardt algorithm(LMA), nonlinear optimum algorithm with high convergent speed and stability, is used to compute them. That is, the signal intensity variate curve is fitted by the gamma-variate function. Various hemodynamic parameters - Cerebral Blood Volume(C.B.V), Mean Transit Time(M.T.T), Cerebral Blood Flow(C.B.F), Time-to-Peak(T.T.P), Bolus Arrival Time(B.A.T), Maximum Slope(M.S) - are computed using LMA.

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MULTI-POINT BOUNDARY VALUE PROBLEMS FOR ONE-DIMENSIONAL p-LAPLACIAN AT RESONANCE

  • Wang Youyu;Zhang Guosheng;Ge Weigao
    • Journal of applied mathematics & informatics
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    • v.22 no.1_2
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    • pp.361-372
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    • 2006
  • In this paper, we consider the multi-point boundary value problems for one-dimensional p-Laplacian at resonance: $({\phi}_p(x'(t)))'=f(t,x(t),x'(t))$, subject to the boundary value conditions: ${\phi}_p(x'(0))={\sum}^{n-2}_{i=1}{\alpha}_i{\phi}_p(x'({\epsilon}i)),\;{\phi}_p(x'(1))={\sum}^{m-2}_{i=1}{\beta}_j{\phi}_p(x'({\eta}_j))$ where ${\phi}_p(s)=/s/^{p-2}s,p>1,\;{\alpha}_i(1,{\le}i{\le}n-2){\in}R,{\beta}_j(1{\le}j{\le}m-2){\in}R,0<{\epsilon}_1<{\epsilon}_2<...<{\epsilon}_{n-2}1,\;0<{\eta}1<{\eta}2<...<{\eta}_{m-2}<1$, By applying the extension of Mawhin's continuation theorem, we prove the existence of at least one solution. Our result is new.