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Relationship between Intake of Milk and Milk Products and Bone Health by Sex and Age-Group in Koreans - Using Data from the Korea National Health and Nutrition Examination Survey 2008~2011 (성별, 연령별에 따른 우유·유제품 섭취와 골 건강과의 관련성 - 2008~2011 국민건강영양조사 자료를 이용하여)

  • Baek, Sang Woo;Lee, Heon Ok;Kim, Hyun Ja;Won, Eun Sook;Ha, Young Sik;Shin, Yong Kook;Om, Ae Son
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.46 no.4
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    • pp.513-522
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    • 2017
  • This study was conducted to examine the relationships between milk and milk product intake and bone health. The data from the 2008~2011 Korean National Health and Nutrition Examination Survey (KNHANES) were used for data analysis. Subjects included 4,626 men and 6,144 women aged 19 to 64 years. Daily intake frequency of milk and milk products was obtained using a food frequency questionnaire and divided into two categories: less than one serving per day and more than one serving per day. Bone mineral density (BMD) values of total femur, femoral neck, and lumbar spine were compared based on daily intake frequency, and relationships between milk and milk product daily intake frequency and osteoporosis risk were evaluated based on logistic regression. In men aged 30~39, BMDs of total femur and femoral neck were significantly higher in the group that consumed milk more than one serving per day (P<0.05). Intake frequency of milk and milk products was also significantly related to both BMDs of total femur and femoral neck. The odds ratio (OR) for milk intake frequency (more than one serving per day) compared to intake frequency less than one serving per day was 0.36 [95% confidence interval (CI) 0.21~0.62], and the OR for milk and milk products intake frequency (more than one serving per day) was 0.49 (95% CI 0.28~0.86) in women aged 50~64. These results indicate that increased consumption of milk and its products is associated with reduced risk of bone health disease, and adequate intakes of milk and milk products might play an important role in maintaining optimum bone health. Further research on the causal relationship and dose-response association between milk intake and bone heath using prospective cohort data is required prior to applying the observed results to programs that prevent bone health problems.

Effects of Total Sleep Deprivation on Fine Motor Performance (전수면박탈이 정상인의 미세운동수행 능력에 미치는 영향)

  • Lee, Heon-Jeong;Song, Hyung-Seok;Ham, Byung-Joo;Suh, Kwang-Yoon;Kim, Leen
    • Sleep Medicine and Psychophysiology
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    • v.8 no.2
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    • pp.129-137
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    • 2001
  • Objectives: The purpose of this study is to investigate the effects of 38-hour sleep deprivation on fine motor performance. The Motor Performance Series (MPS) in the Vienna Test System (computerized neurocognitive function tests) was used in this study. Methods: Twenty four subjects participated in this study. Subjects had no past history of psychiatric disorders and physical illness. Subjects had normal sleep-waking cycle without current sleep disturbances and were all right-handed (Annett's Hand Preference Questionnaire: above +9 points). To minimize the learning effects, familiarization with the Vienna Test System was performed one day before the study. Subjects were to get up at 6:00 in the morning after getting enough sleep according to his or her usual sleep-wake cycle. After awakening, subjects remained awake for 38 hours under continuous surveillance. During two consecutive study days, the subjects tested MPS at 7 AM and 7 PM each day, which means the MPS was done four times in total. During the experiment, anything that could affect the subjects' sleep such as coffee, tea, alcohol, a nap, tiring sports, and all medications were prohibited. Results: In MPS, the fine motor functions of both hands decreased after 38 hours of sleep deprivation. The decrement in motor performance was prominent in the dominant right hand. In the right hand, the total number of tapping was reduced (p<.005), and the number of misses (p<.05) and the length of misses (p<.05) of line tracking, the total length of inserting a short pin (p<.01), the total length of inserting a long pin (p<.05), and the number of misses in aiming (p<.05) increased. Such performance decrement was distinct in the morning sessions. Conclusions: These results suggest that fine motor performance decrement during sleep deprivation is predominant in the right hand, which exerts maximal motor function. The finding of decrement in motor function in tapping during sleep deprivation also suggested that the time required for exhaustion of muscles is shortened during sleep deprivation. More deterioration of motor performance was shown in the morning, which could be explained as circadian rhythm effects.

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Protective Effects of Chaenomeles sinensis Koehne Extract on Ethanol-induced Liver Damage in Rat (에탄올에 의해 유발된 간독성에 대한 모과 추출물의 보호효과)

  • Lee, Yu-Mi;Lee, Jae-Joon;Shin, Hyoung-Duck;Lee, Myung-Yul
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.10
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    • pp.1336-1342
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    • 2006
  • This study was performed to investigate the effect of ethanol extract of Chaenomeles sinensis Koehne (CS) on alcohol-induced liver damage in rats. Male Sprague-Dawley rats weighing $135{\pm}10g$ were divided into 6 groups for 4 weeks; normal group (ND), alcohol (35%, 10 mL/kg/day) treated group (ET), CS ethanol extract 200 mg/kg/day treated group (ND-CSL), CS ethanol extract 400 mg/kg/day treated group (ND-CSH), CS ethanol extract 200 mg/kg/day and alcohol treated group (ET-CSL), and CS ethanol extract 400 mg/kg/day and alcohol treated group (ET-CSH). The body weight gain and food efficiency ratio were no differences between ND and ET. There were increases in the activities of serum alanine aminotransferase (ALT), asparate aminotransferase (AST), and alkaline phosphatase (ALP) in ET. On the other hand, the administration of CS decreased ALT, AST and ALP activities in serum. It was also observed that the hepatic activities of superoxide dismutase (SOD), catalase, glutathione peroxidase (GSH-Px) and xanthine oxidase (XO) increased by alcohol treatment were also markedly decreased in the CS administered groups as compared with ET. The activities of hepatic SOD, catalase, GSH-Px and XO were riot significantly different among the normal diet groups. Contents of thiobarbituric acid reactive substances (TBARS) were increased by the administration of alcohol, on the other hand, the administration of CS reduced TBARS value in the liver. In addition, the content of glutathione (GSH) in the liver was decreased by alcohol administration, however, GSH increased after administering CS. In conclusion, the administration of alcohol develops the hyperoxidation of liver lipids through tile increase in enzymes activity related to the lipid peroxiation, however, it was decreased after administring CS. Thus, CS may have a possible protective effect on ethanol-induced hepatotoxicity in rat liver.

Effect of Nutrient Supply Cut-off Periods Before Harvest on Storability of Chicon (수확 전 단수처리가 치콘 저장성에 미치는 영향)

  • Jung, Hyun-Jin;Choi, In-Lee;Son, Jin-Sung;Seo, Hyun-Taek;Won, Jae-Hee;Kang, Ho-Min
    • Journal of Bio-Environment Control
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    • v.20 no.4
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    • pp.406-411
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    • 2011
  • This study was conducted to find out the effect of cut-off period (0 hour, 3 hours, 6 hours, 12 hours, and 24 hours) to supply nutrient solution for chicon forcing at that was predrying treatment on the storability of chicon. The cut-off treatment increased dry matter rate, respiration rate, and ethylene production rate. The dry matter rate of chicon increased, as the cut-off period increased, but the respiration rate and ethylene production rate of chicon was highest in 12 hours and 6 hours cut-off treatment, respectively, and then their rates decreased, as the cut-off period prolonged. The weight loss at cut-off 6 hours treatment was lower than other treatments during $10^{\circ}C$ storage temperature. The cut-off 6 hours treatment showed higher carbon dioxide and oxygen concentration in 10,000 cc/$m^2$/day/atm oxygen permeability film package during storage period than control and showed a little predrying effect but was not statistically significant. At $4^{th}$ day, the ethylene concentration reached higher than other storage day and after that decreased but was not statistically significant. The quality of chicon for 3 hours, 6 hours, 24 hours cut-off treatments on storability showed higher than other treatments, accordingly. The 6 hours cut-off treatment showed the inhibited effect of the degree of browning of chicon cutting plane. The effect of 6 hours cut-off treatment on storability of chicon showed proper predrying effect, reduced moisture loss and browning inhibition apparently during $10^{\circ}C$ storage.

Effects of Postharvest Treatments of Calcium, Lysophosphatidyl ethanolamine (LPE), and 1-Methylcyclopropene (1-MCP) on the Fruit Quality during Simulated Marketing in Asian Pears (Pyrus pyrifolia Nakai) (모의유통 환경에서 동양배 품질에 미치는 수확 후 칼슘, Lysophosphatidyl ethanolamine (LPE), 1-Methylcyclopropene (1-MCP) 처리의 영향)

  • Lee, Ug-Yong;Choi, Jin-Ho;Lee, Jin-Wook;Kim, Joonyup;Kim, Ui-Dong;Chun, Jong-Pil
    • Journal of Bio-Environment Control
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    • v.27 no.4
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    • pp.312-318
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    • 2018
  • We investigated the effect of postharvest treatments of calcium chloride, lysophosphatidyl ethanolamine (LPE) or 1-methylcyclopropene (1-MCP) on fruit quality during simulated marketing in Asian pear (Pyrus pyrifolia Nakai). 'Whangkeumbae' pear fruits were immersed in 0.25, 0.5 or 1.0% $CaCl_2$ solution with or without ultrasound (40kHz) at $25^{\circ}C$ for 3min followed by storage at $1^{\circ}C$ for 30 days simulated as abroad exportation. After simulated marketing at $25^{\circ}C$ and 80% relative humidity (RH) up for 10 days, quality parameters were evaluated. Results indicated that the ultrasound and $CaCl_2$ treatment had a synergic effect on keeping the green skin color which showed lower $a^*$ value. The combination treatment of ultrasound and 0.5% and 1.0% $CaCl_2$ significantly reduced internal browning disorders, although severe skin blemish disorder (20-23%) occurred in 1.0% $CaCl_2$ treatment. 'Wonhwang' pears were immersed in 1,000ppm LPE for 3 minutes or were fumigated in 1,000 ppb 1-MCP for 12 hours, respectively. The results of the fruit quality survey during the 21 days of distribution period are as follows. The 1-MCP treatment was maintained at a constant flesh firmness of 33N or higher during the distribution period. The LPE treated fruits had a lower physiological disorder index than the untreated group, but showed a relatively higher value than the 1-MCP treated group. In the case of 1-MCP treatment, the fruit respiration rate was significantly lower than of untreated control ($6.0mL{\cdot}kg^{-1}{\cdot}hr^{-1}$) during the simulaed marketing period. Consequently, it was expected that the postharvest treatments of 0.5% calcium chloride in pararell with ultrasound and 1-MCP fumigation can help to maintain Asian pear quality during distribution period.

Anti-inflammatory effects of Ishige sinicola ethanol extract in LPS-induced RAW 264.7 cell and mouse model (LPS로 유도된 RAW 264.7 Cell과 마우스 모델에 대한 넓패(Ishige sinicola) 에탄올 추출물의 항염증 효과)

  • Kim, Ji-Hye;Kim, Min-Ji;Kim, Koth-Bong-Woo-Ri;Park, Sun-Hee;Cho, Kwang-Su;Kim, Go-Eun;XU, Xiaotong;Lee, Da-Hye;Park, Ga-Ryeong;Ahn, Dong-Hyun
    • Food Science and Preservation
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    • v.24 no.8
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    • pp.1149-1157
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    • 2017
  • Inflammation is the first response of the immune system to infection or irritation in our body. The use of medicinal plants has been widely applied as an alternative source for drug development. One of marine natural resources, the anti-inflammatory effect of Ishige sinicola ethanol extract (ISEE), was evaluated by using LPS-induced RAW 264.7 cell and mice model. As a result, the production of nitric oxide (NO) and pro-inflammatory cytokines (IL-6, IL-$1{\beta}$, TNF-${\alpha}$) were inhibited with increasing concentration of ISEE without any cytotoxicity. Furthermore, ISEE suppressed the expression of not only inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), nuclear factor-kappa B (NF-${\kappa}B$) p65, and mitogen-activated protein kinases (MAPKs), including extracellular signal-regulated kinase (ERK) 1/2, p38, and c-Jun N-terminal kinase (JNK) in a dose-dependent manner. In mice ear edema test, the formation of edema was reduced at the highest dosage of ISEE and the reduction of the number of infiltrated mast cells was observed in histological analysis. These results indicate that ISEE has a potent anti-inflammatory activity and can be used as a pharmaceutical material for many kinds of inflammatory disease.

Changes of Vegetation Structure in Naejangsan District, Najangsan National Park for Twenty Years(1991~2010), Korea (내장산국립공원 내장산지구 20년간(1991~2010년) 식생구조 변화 연구)

  • Bae, Ji-Yoon;Kim, Ji-Suk;Lee, Kyong-Jae;Kim, Jong-Yup;Yeum, Jung-Hun
    • Korean Journal of Environment and Ecology
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    • v.27 no.1
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    • pp.99-112
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    • 2013
  • This study aims to show the changes of characteristics of vegetation structure for 20 years(1991~2010) in Naejangsan National Park. As a result of analysis of actual vegetation, the mixed community of Quercus variabilis and Quercus serrata was distributed with 56.1%, and Q. variabilis community showed in southern steep slope with 17.6%. Pinus densiflora community(5.8%) was observed on the ridge and Carpinu tschonoskii community distributed in the slope of the valley with 6.6%. Zelkova serrata and Prunus sargentii community were distributed in valley. The classification by TWINSPAN, ordination by DCA considering importance percentage and property of vegetation class were divided into 4 communities, which are community I(P. densiflora-Q. variabilis community), community II(Q. variabilis community), community III(C. tschonoskii community) and community IV(Mixed deciduous broad-leaved trees community). The age of Pinus densiflora was 32years old and Q. serrata was 36 years old in the community I, that of Q. variabilis was 64 years old in the community II, Q. serrata was 46 years old and C. tschonoskii was 45 years old in the community III, and Acer palmatum was 54 years old and Cornus controversa was 47 years old in the community IV. As the result of Shannon's index of species diversity, the community Iwas ranged from 0.9751 to 1.4199, community II was ranged from 1.0765 to 1.3278, community III was ranged from 1.0353 to 1.2881, and community IV was ranged from 1.1412 to 1.3807. The change of vegetation structure analyzed through the comparison with results of studies carried out 20 years ago were natural selection of P. densiflora, expansion of Quercus spp. and increase of C. tschonoskii. Especially, A. palmatum is dominated by Q. variabilis in canopy layer like the result of study 20 years ago. A. palmatum was analysed by 14.6% in the canopy layer of only mixed deciduous broad-leaved trees community. As a result of analysis of habitat property of Q. variabilis and A. palmatum, Q. variabilis was distributed in dry area with the low value of pH, O.M., exchangeable cations and Avail. P, and A. palmatum was located in the wet valley with huge value of nourishment. The tendency of reduction of bio-diversity by Sasa borealis is same as previous study but, the distributed areas were reduced in Naejangsan area.

Methodologies for Enhancing Immersiveness in AR-based Product Design (증강현실 기반 제품 디자인의 몰입감 향상 기법)

  • Ha, Tae-Jin;Kim, Yeong-Mi;Ryu, Je-Ha;Woo, Woon-Tack
    • Journal of the Institute of Electronics Engineers of Korea CI
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    • v.44 no.2 s.314
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    • pp.37-46
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    • 2007
  • In this paper, we propose technologies for enhancing the immersive realization of virtual objects in AR-based product design. Generally, multimodal senses such as visual/auditory/tactile feedback are well known as a method for enhancing the immersion in case of interaction with virtual objects. By adapting tangible objects we can provide touch sensation to users. A 3D model of the same scale overlays the whole area of the tangible object so the marker area is invisible. This contributes to enhancing immersion. Also, the hand occlusion problem when the virtual objects overlay the user's hands is partially solved, providing more immersive and natural images to users. Finally, multimodal feedback also creates better immersion. In our work, both vibrotactile feedback through page motors, pneumatic tactile feedback, and sound feedback are considered. In our scenario, a game-phone model is selected, by way of proposed augmented vibrotactile feedback, hands occlusion-reduced visual effects and sound feedback are provided to users. These proposed methodologies will contribute to a better immersive realization of the conventional AR system.

High Resolution Gravity Mapping and Its Interpretation from both Shipborne and Satellite Gravity Data in the Ulleung Basin (울릉분지에서의 선상중력과 위성중력 통합에 의한 중력 해상도 향상 및 해석)

  • Park, Chan Hong;Kim, Jeong U;Heo, Sik;Won, Jung Seon;Seok, Bong Chul;Yu, Hae Su
    • Journal of the Korean Geophysical Society
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    • v.2 no.1
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    • pp.27-38
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    • 1999
  • The errors between track segments or at the cross-over points of shipborne gravity were successfully reduced by applying a cross-over error adjustment technique using satellite gravity. The integration of shipborne and satellite altimeter-implied free-air gravity anomalies after the cross-over error adjustment resulted in a high resolution gravity map which contains both short and long wavelength components. The successful adjustment of the cross-over errors in the shipborne gravity using the satellite gravity suggests that the shipborne gravity can be combined with the satellite anomalies characterized by a stable and long wavelength component. The resulting free-air anomaly map is evenly harmonized with both short and long wavelength anomalies. Thus the corrected anomaly map can be better used for the geological interpretation. Free-air anomalies with more than 140 mGal in total variations generally correspond to the seafloor topographic changes in their regional patterns. A series of gravity highs are aligned from the Korea Plateau to the Oki Island, which are interpreted to be caused by seamounts or volcanic topographies. The gravity minima along the western and southern shelf edge are associated not only with the local basement morphology and thick sediment fill at the continental margin, but also possibly with the crustal edge effect known for passive continental margins. Series of NE-trending linear anomalies are possibly caused by a swarm of volcanic intrusions followed the initial opening of the Ulleung Basin. The linear high anomalies in the Ulleung Plateau are terminated by the straightly NNW-trending anomalies with a sharp gradient in its western boundary which indicates a fault-line scarp. The opposite side adjoined with the fault-line scarp shows no correlation with the fault-line scarp in geometry indicating that the block might be horizontally slided from the north. A gravity high in contrast to the deepening in seafloor toward the northeastern central Ulleung Basin is probably responsible for the thin crust and shallow seated mantle. The gravity minima along the western and southern shelf edge are associated not only with the local basement morphology and thick sediment fill at the continental margin, but also possibly with the crustal edge effect known for passive continental margins. Series of NE-trending linear anomalies are possibly caused by a swarm of volcanic intrusions followed the initial opening of the Ulleung Basin. The linear high anomalies in the Ulleung Plateau are terminated by the straightly NNW-trending anomalies with a sharp gradient in its western boundary which indicates a fault-line scarp. The opposite side adjoined with the fault-line scarp shows no correlation with the fault-line scarp in geometry indicating that the block might be horizontally slided from the north. A gravity high in contrast to the deepening in seafloor toward the northeastern central Ulleung Basin is probably suggestive of a thin crust and shallow seated mantle.

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Separation of Reducing Sugars from Rape Stalk by Acid Hydrolysis and Fabrication of Fuel Pellets from its Residues (산가수분해한 유채대로부터 유리당의 분리 및 이의 잔사로부터 펠릿의 제조)

  • Yang, In;Ahn, Byoung Jun;Kim, Myeong-Yong;Oh, Sei Chang;Ahn, Sye Hee;Choi, In-Gyu;Kim, Yong-Hyun;Han, Gyu-Seong
    • Korean Journal of Plant Resources
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    • v.27 no.1
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    • pp.60-71
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    • 2014
  • This study was conducted to identify the potential of rape stalk as a raw material for biorefinery process of rape flower. At first, rape stalk (RS) was immersed in distilled water (DW), acetic acid (AA), oxalic acid (OA), sulfuric acid (SA) and sodium hydroxide (SH) solutions, and the content of reducing sugars liberated from immersed RS was analyzed. Glucose, xylose, arabinose and sucrose were detected varying with the immersion type. In particular, 1% AA-immersion of RS for 72 hr was the most effective conditions to liberate glucose from RS. Secondly, the RS residues were used for elementary analysis and fabrication of fuel pellets. In addition to the solution type, concentration of immersion solutions (0%, 1%, 2%) and immersion time (24, 72, 120 hr) were used as experimental factors. The contents of nitrogen, sulfur and chlorine reduced effectively through the immersion of RS in DW, AA and OA solutions. For properties of RS-based pellets, bulk density and higher heating value of RS-based pellets greatly increased with the immersion of RS, and the qualities were much higher than those of the A-grade pellet of the EN standards. Ash content decreased remarkably through the immersion of RS, and was satisfied with the A-grade pellet standard. Durability was negatively affected by the immersion of RS, and did not reached to B-grade of the EN standard. In conclusion, acid immersion of RS can be a pretreatment method for the production of fuel pellet and bioethanol, but use of the immersed RS for the production of high-quality pellets might be restricted due to low durability of immersed-RS pellets. Therefore, further studies, such as investigation of detailed immersion conditions, fabrication of mixed pellets with wooden materials and addition of binders, are needed to resolve the problems.