• Title/Summary/Keyword: M-H loop

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Analysis of characteristic linear Halbach array (영구자석 선형 Halbach 배열의 특성 해석)

  • Jang, S.M.;Cha, S.D.;Lee, S.H.;Kim, B.S.;Sung, H.K.;Cho, H.J.
    • Proceedings of the KIEE Conference
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    • 2001.07b
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    • pp.892-894
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    • 2001
  • This paper presents analysis linear Halbach array. For the theoretical aspects of this paper, the time variation of electric field related quantities is insignificant. A result of analytical method to calculate the magnetic flux density compared with a result of numerical method. Also when linear Halbach array moves above a closed loop, a developed force between linear Halbach array and a closed loop is analyzed.

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Development of reverse transcription loop-mediated isothermal amplification assays for point-of-care testing of avian influenza virus subtype H5 and H9

  • Zhang, Songzi;Shin, Juyoun;Shin, Sun;Chung, Yeun-Jun
    • Genomics & Informatics
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    • v.18 no.4
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    • pp.40.1-40.8
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    • 2020
  • Avian influenza (AIV) outbreaks can induce fatal human pulmonary infections in addition to economic losses to the poultry industry. In this study, we aimed to develop a rapid and sensitive point-of-care AIV test using loop-mediated isothermal amplification (LAMP) technology. We designed three sets of reverse transcription LAMP (RT-LAMP) primers targeting the matrix (M) and hemagglutinin (HA) genes of the H5 and H9 subtypes. RT-LAMP targeting the universal M gene was designed to screen for the presence of AIV and RT-LAMP assays targeting H5-HA and H9-HA were designed to discriminate between the H5 and H9 subtypes. All three RT-LAMP assays showed specific amplification results without nonspecific reactions. In terms of sensitivity, the detection limits of our RT-LAMP assays were 100 to 1,000 RNA copies per reaction, which were 10 times more sensitive than the detection limits of the reference reverse-transcription polymerase chain reaction (RT-PCR) (1,000 to 10,000 RNA copies per reaction). The reaction time of our RT-LAMP assays was less than 30 min, which was approximately four times quicker than that of conventional RT-PCR. Altogether, these assays successfully detected the existence of AIV and discriminated between the H5 or H9 subtypes with higher sensitivity and less time than the conventional RT-PCR assay.

Design of Cartesian Feedback Loop Linearization Chip for UHF Band (UHF 대역용 Cartesian Feedback Loop 선형화 칩 설계)

  • Kang, Min-Soo;Chong, Young-Jun;Oh, Seung-Hyeub
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.21 no.5
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    • pp.510-518
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    • 2010
  • In this paper, the designed and implemented results of CFL linearization chip which can be used in mobile radio and TRS terminal of UHF band(380~910 MHz), using $0.6\;{\mu}m$ BiCMOS process based on Si, are shown. As gain control circuits for modifying transmit power are inserted not only in feedback path but also in forward path, the stability of CFL is maintained. And, DC-offset correction function of S/H structure, which is suitable for walkie-talkie PTT operation and is easily implemented, is realized. The performance test results of transmitter show that the regulation of FCC emission mask at PEP 3 W(34.8 dBm) is satisfied when the CQPSK modulated signal is fed and more than 30 dBc improvement of 3rd order IMD is achieved when two-tone signal is inputted.

Design and Estimation of a Spindle System for Centerless Grinding Machine (무심연삭기 주축계의 설계 및 성능평가)

  • Park C.H.;Hwang J.H.;Oh Y.J.;Cho S.J.
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2005.06a
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    • pp.86-89
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    • 2005
  • Design and estimation of a spindle system which was composed of grinding spindle and regulating spindle for the centerless grinding of ferrule was performed and prototypes of each spindle were manufactured. Loop stiffness of the spindle system was 130 N/${\mu}m$. Although the value was lower than the target value of 150 N/${\mu}m$, as there included 20% of the safety factor, it was enough to machine the ferrule. Rotational accuracies of each spindle were about 0.2${\mu}m$ at the primary speed of 2,300 rpm(grinding spindle) and 300 rpm(regulating spindle). Temperature rises at the same speed were about $4.4\;\~\;4.7^{\circ}C$ in the case of grinding spindle and $1.8^{\circ}C$in the case of regulating spindle, which were well agreed with the designed value. From these results, it was estimated that the prototype of spindle system had a enough performances for the centerless grinding machine to machine the ferrule.

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The Magnetic Characteristics of Co-Cr Thin Films Deposited by Facing Targets Sputtering (대향타겟식 스퍼터로 제작된 Co-Cr 박막의 자기적 특성)

  • Kim, K.H.;Son, I.H.;Kim, M.H.;Kim, J.H.;Nakagawa, S.;Naoe, M.
    • Proceedings of the KIEE Conference
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    • 1997.07d
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    • pp.1320-1322
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    • 1997
  • The distribution of coercivity in the thickness direction were investigated by using Kerr hysteresis loop tracer for the Co-Cr films deposited by Facing Targets Sputtering apparatus. It $H_{c{\bot}}(S)- H_{c{\bot}}(I)$ correlated strongly with ${\Delta}H_c$, which represents the degree of distribution of coercivity. Furthermore, the Cr content was varied in order to improve the coercivity of intial growth layer $H_{c{\bot}}(I)$ took a maximum value of 750 Oe and the distribution of coercivity became sharper at the Cr content of 25 at.%.

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Ginsenoside Rh2 reduces m6A RNA methylation in cancer via the KIF26B-SRF positive feedback loop

  • Hu, Chunmei;Yang, Linhan;Wang, Yi;Zhou, Shijie;Luo, Jing;Gu, Yi
    • Journal of Ginseng Research
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    • v.45 no.6
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    • pp.734-743
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    • 2021
  • Background: The underlying mechanisms of the potential tumor-suppressive effects of ginsenoside Rh2 are complex. N6-methyladenosine (m6A) RNA methylation is usually dysregulated in cancer. This study explored the regulatory effect of ginsenoside Rh2 on m6A RNA methylation in cancer. Methods: m6A RNA quantification and gene-specific m6A RIP-qPCR assays were applied to assess total and gene-specific m6A RNA levels. Co-immunoprecipitation, fractionation western blotting, and immunofluorescence staining were performed to detect protein interactions and distribution. QRT-PCR, dual-luciferase, and ChIP-qPCR assays were conducted to check the transcriptional regulation. Results: Ginsenoside Rh2 reduces m6A RNA methylation and KIF26B expression in a dose-dependent manner in some cancers. KIF26B interacts with ZC3H13 and CBLL1 in the cytoplasm of cancer cells and enhances their nuclear distribution. KIF26B inhibition reduces m6A RNA methylation level in cancer cells. SRF bound to the KIF26B promoter and activated its transcription. SRF mRNA m6A abundance significantly decreased upon KIF26B silencing. SRF knockdown suppressed cancer cell proliferation and growth both in vitro and in vivo, the effect of which was partly rescued by KIF26B overexpression. Conclusion: ginsenoside Rh2 reduces m6A RNA methylation via downregulating KIF26B expression in some cancer cells. KIF26B elevates m6A RNA methylation via enhancing ZC3H13/CBLL1 nuclear localization. KIF26B-SRF forms a positive feedback loop facilitating tumor growth.

Development of a irradiation strategy within a closed loop control system for the laser adjustment of deformation

  • Hutterer, A.;Hagenah, H.;Geiger, M.
    • 제어로봇시스템학회:학술대회논문집
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    • 2003.10a
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    • pp.2313-2318
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    • 2003
  • By means of flexible forming processes in sheet metal manufacturing it is possible to produce parts of complex geometry within short manufacturing time. These procedures are suitable especially for prototyping or adjustment of deformation. Here formative procedures like laser forming are increasingly important, because they make the large-scale-like production of the prototypes with the required materials possible. High accuracy and reproducibility of the products is the precondition of the production. Due to the lack of a forming tool, complex geometries can hardly be manufactured within tolerances. To overcome this problem an automatic closed loop control system for the adjustment of deformations has been developed. An important element of the closed loop control system is the definition of a suitable irradiation strategy for laser forming. For the determination of the irradiation strategy a lot of influences must be taken into consideration from the field of material, geometry and laser. In this paper the improved closed loop control system and the development of an irradiation strategy for 4 mm deep buckles in an ALMgSi1 sheet will be represented. This system can be used e.g. in the automated adjustment of hail damage in car bodies or deformation by heat treatment.

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A Study on the Operating Characteristics and System Modelling of Closed Loop Type Thermosyphon (루프형태의 밀폐형 Thermosyphon의 작동특성과 시스템 모델링에 관한 연구)

  • Kang, M.C.;Kang, Y.H.;Lee, D.G.
    • Journal of the Korean Solar Energy Society
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    • v.22 no.2
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    • pp.39-47
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    • 2002
  • The thermosyphon SDHWS and the loop type thermosyphon systems are widely used for domestic hot water system. The loop type thermosyphon is a circulation device for transferring the heat produced at the evaporator to the condenser area in the loop. In this study, the operating characteristics of various working fluids being used have been identified. The working fluids employed in the study were ethanol. water, and a binary mixture of ethanol and water. The volume of working fluid used in this study were 30%, 40%, 50%, 60% and 70% of evaporator volume. It is observed that, in the thermosyphon with low volume of working fluid, such as 30% or 40%, the fluid was dried out. The flow pattern and mechanism of the heat transfer were identified through this study. Flow patterns of the binary mixture working fluid were also investigated, and the patterns were recorded in the camera. The system parameters were calculated using the thermal performance data. Modelling of the system was carried out using PSTAR method and TRNSYS program.

Development of a gamma irradiation loop to evaluate the performance of a EURO-GANEX process

  • Sanchez-Garcia, I.;Galan, H.;Nunez, A.;Perlado, J.M.;Cobos, J.
    • Nuclear Engineering and Technology
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    • v.54 no.5
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    • pp.1623-1634
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    • 2022
  • A new irradiation loop design has been developed, which provides the ability to carry out radiolytic resistance studies of extraction systems simulating process relevant conditions in an easy and simple way. The step-by-step loop configuration permits an easy modification of settings and has a relative low volume requirement. This irradiation loop has been initially set up to test the main EURO-GANEX process steps: the lanthanide (Ln) and actinide (An) co-extraction followed by the transuranic (TRU) stripping. The performance and changes in the composition have been analyzed during the irradiation experiment by different techniques: gamma spectroscopy and ICP-MS for the extraction and corrosion behavior of the full system, and HPLC-MS and Raman spectroscopy to determine the degradation of the organic and aqueous solvents, respectively. The Ln and An co-extraction step and the corrosion that occurred during the first irradiation step revealed the favorable expected results according to literature. The effects of acidity changes occurred during the irradiation process, the presence of stainless corrosion products in solution as well as the new possible degradation compounds have been explored in the An stripping step. The results obtained demonstrate the importance of developing realistic irradiation experiments where different factors affecting the performance can be easily studied and isolated.

The development of multi-loop generator control system with IGBT converter (IGBT를 이용한 디지털 다중화 발전기 제어시스템 개발)

  • Lee, J.H.;Ryu, H.S.;Sin, M.S.;Lim, T.H.
    • Proceedings of the KIEE Conference
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    • 2004.07d
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    • pp.2266-2268
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    • 2004
  • 전력수요의 증대로 발전기 전압제어를 통해 전력계통의 안정과 양질의 전력공급의 중요한 역할을 하는 여자시스템의 중요성이 한층 더 증대되었다. 본 논문은 선진 외국 제작사 기술에 전적으로 의존하고 있는 발전기 제어시스템을 순수 국내기술로 개발하여 교체하기 위해 제어시스템의 개발내용과 모의시험 및 현장 적용을 통한 시험 및 성능을 평가한 내용을 기술하였다.

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