• Clinical and Experimental Pediatrics
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• 제58권12호
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• pp.478-483
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• 2015

Purpose: Information on the clinical features of lung abscess, which is uncommon in children, at hospitalization is helpful to anticipate the disease course and management. There is no report concerning lung abscess in Korean children. We aimed to identify the clinical characteristics of pediatric lung abscess and compare the difference between primary and secondary abscess groups. Methods: The medical records of 11 lung abscess patients (7 males and 4 females) from March 1998 to August 2011 at two university hospitals were retrospectively reviewed. The clinical characteristics, symptoms, underlying disease, laboratory and radiologic findings, microbiological results, and treatments were examined. Results: Six patients had underlying structural-related problems (e.g., skeletal anomalies). No immunologic or hematologic problem was recorded. The mean ages of the primary and secondary groups were 2.4 and 5.3 years, respectively, but the difference was not statistically significant. The mean length of hospital stay was similar in both groups (22.8 days vs. 21.4 days). Immunologic studies were performed in 3 patients; the results were within the normal range. Most patients had prominent leukocytosis. Seven and 4 patients had right and left lung abscess, respectively. Staphylococcus aureus, Streptococcus pneumoniae, and antimycoplasma antibodies were detected in both groups. Two patients with primary lung abscess were administered antibiotics in the absence of other procedures, while 8 underwent interventional procedures, including 5 with secondary abscess. Conclusion: The most common symptoms were fever and cough. All patients in the primary group were younger than 3 years. Structural problems were dominant. Most patients required interventional procedures and antibiotics.

• 동의생리병리학회지
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• 제19권4호
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• pp.1078-1081
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• 2005

Lung abscess is often ocuured by aspiration of infectious secretion in stroke patients that has symptom of dysphagia. So we studied the effects of combined eastern and western treatment in lung abscess patient combined with stroke. We performed both antibiotic therapy and herbal medication in a lung abscess patient. We compared a chest x-ray film of early stage of disease with a film of after stage of disease, also compared change of symptom-cough, sputum, flank pain, blood phlem. After dispending antibiotic therapy and herbal medication, a lung abscess patient improved symptoms and in result of chest x-ray. The above results suggest that combined eastern and western trearment can have good effects on improving symptoms of a lung abscess patient.

• Journal of Chest Surgery
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• 제20권3호
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• pp.552-556
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• 1987

During the preantibiotic era, lung abscess carried a high mortality, however, with the introduction of penicillin and subsequently other antibiotics, significant improvement was resulted. Clinical review was performed on 27 cases of lung abscess, those were admitted and treated at the Department. of Thoracic and Cardiovascular Surgery, Chonbuk University Hospital, from 1979 to August, 1986. The following results were obtained. The most common age of occurrence was between the age of 40 and 60 [14 cases] and 22 cases were male patients. The common symptoms were cough, putrid sputum production, fever and chilliness. Numerous etiological factors may play a role in the formation of lung abscess; pneumonia [7 cases], aspiration [5 cases], bronchiectasis [2 cases], liver abscess [1 case] and broncholith [1 case]. The bacteriologic study revealed increased incidence of Enterobacteriaceae [15 cases]. The treatment methods were postural drainage [12 cases]. pneumonostomy [5 cases], lobectomy [8 cases], thoracostomy [2 cases].

• Tuberculosis and Respiratory Diseases
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• 제62권6호
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• pp.540-544
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• 2007

폐농양의 치료 중에 발생하는 기질화 폐렴은 흔하게 관찰 되는 소견은 아니다. 기질화 폐렴은 특별한 원인 없이 발생하기도 하지만, 감염의 치료 과정에서 이차적 기질화 폐렴이 발생 할 수도 있다. 본 증례는 62세 남자 환자에서 폐농양을 치료하는 과정에서 발생한 기질화 폐렴을 경기관지 폐생검을 통해 확인하고 부신피질 호르몬을 투여로 효과적으로 치료한 예를 경험하였기에 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제40권4호
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• pp.449-453
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• 1993

A 64-year-old male was admitted due to abruptly developed, severe dyspnea via local clinic. He had been a heavy smoker and alcoholic for a long time. Chest PA showed huge haziness in right upper lung field. Sputum culture for bacteriology was positive for Klebsiella pneumoniae. Immediately, appropriate antibiotics were administered and artificial ventilation was started. On 40th hospital day, simple chest roentgenogram taken due to sudden aggravated dyspnea showed marked hyperlucency in right upper lung field, suggestive of rupture of abscess cavity and resultant pneumothorax. At that time, chest tube was inserted but air leakage from the chest tube persisted. Chest CT scan taken after chest tube insertion showed the tube inserted into a thin-walled cavity in the above lesion. on 84th hospital day, right upper lobectomy with decortication was performed. Pathologically, cavittary lung abscess was diagnosed on the findings of partial re-epithelialization of ciliated columnar epithelium with severe pulmonary vascular occlusion and extensive fibrous pleural adhesions.

• 동의생리병리학회지
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• 제20권2호
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• pp.292-304
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• 2006

The Atrophy of lung among chronic asthenia disease is a kind of tuberculosis. It is divided in two types. One is the Atrophy of lung with consumptive fever, the other is the Atrophy of lung with consumptive cold. Four prescriptions can be used treat this disease. Pulmonary abscess(肺癰) is infected by poisonous fatcors of wind and heat. It's symptoms like coughing, chest pain, fever and phlegm with pus after coughing are appeared generally, in case of serious condition, pyemia after coughing can be appeared. This disease is applicable to lung abscess, bronchiectasis, lung gangrene. Six prescriptions can be used to treat this disease. Coughing and congestion of the head(咳嗽上氣) is called Lung-distension(肺腸). Its symptom is dyspnea caused by more expiration rather than inspiration. This disease is divided into two types like chronic asthenia type and inflammatory type. Seven prescriptions can be used to treat this disease.

• Tuberculosis and Respiratory Diseases
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• 제43권4호
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• pp.571-578
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• 1996

배 경 : 폐 농양은 괴사된 폐실질에 농이 고이는 질환으로 1940년대 이전까지는 폐 농양은 체외 배액술에 의한 방법이 치료 원칙이었으나 피 이후 파양한 항생제의 발달로 대부분의 폐 농양에서는 항생제와 체위적 배농술을 포함한 내과적 치료법이 매우 효과적으로 이용되어 왔고 내과적 치료에 실패한 경우에 한해서 폐엽 절제를 포함한 외과적 치료 방법이 적용되어 왔다. 농흉은 흉막강내에 농이 고이는 질환으로 흉수 그람 염색상 양성이어야 하고 약제의 효과적인 침투가 어려우므로 내과적인 치료만으로 치유를 기대할 수 없고 흉관삽관 등 수술적인 조작이 필요하다. 하지만 최근 환자의 전신상태가 불량하거나 외과적 폐절제술이 용이하지 않는 경우에 국소 마취로 직경이 작은 카테타를 사용하여 경피적으로 배농시켜 치료하는 방법을 시행하고 있다. 이에 본 연구에서는 한양대학병원에 내원한 폐 농양 10례와 농흉 23례의 환자를 대상으로 pig-tail 도관 배액술을 시행하였기에 이에 대한 치료 효과를 보고하는 바이다. 대상 및 방법 : 1990년 1월 1일부터 1996년 5월 20일까지 한양대학병원에서 입원 치료한 환자중에서 pig-tail 도관을 이용하여 치료한 폐 농양 환자 10례와 농흉 환자 23례를 대상으로 하였고 각 환자들은 도관 배액술 전에 단순 흉부 X-선사진과 흉부 전산화 단층촬영을 하였고 형광 투시 또는 초음파 유도하에서 천자를 시행하였다. 천자후 카테타는 배액이 잘 되는 위치에서 피부에 고정되어었고 매일 배액량을 관찰한 후 3-4일 간격으로 단순 흉부 X-선사진을 검사하여 폐 농양의 크기나 농흉의 크기가 줄고 임상적 호전이 있으면서 배농량이 하루 5ml이하일때 도관을 제거하였다. 결 과 : 원인균은 폐 농양에서는 Staphylococcus aureus aureus 1례, Klebsiella pneumoniae 1례였으며 농흉에서는 결핵균이 14례로 가장 많았고 2례에서는 Streptococcus pneumoniae 였고 나머지에서는 균의 성장을 관찰할 수 없었다. 카테타의 삽입기간은 폐농양에서는 1-2주 사이가 7례(70%)였으며 농흉에서도 1-2주 사이가 14례(60.8%)로 가장 많았다. 경피적 배농은 29례(87.8%)에서 성공적이었으며 그 중 20례(60.6%)에서는 그 크기가 빠르게 감소되었다. 결 론 : 폐 농양과 농흉에서 pig-tail도관을 통한 배농은 항생제 요법과 보조 요법에 반응하지 않는 경우와 외과적인 수술의 어려움이 있는 환자들에서 비교적 안전하게 선택할 수 있는 효과적인 치료 방법으로 생각된다.

• Tuberculosis and Respiratory Diseases
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• 제41권2호
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• pp.120-126
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• 1994

연구배경 : 내과적 치료에 반응이 없는 폐농양 환자와 감염성 낭포환자에서 대체 치료방법은 폐농양 환자에서는 페엽절제술과 같은 수술이나 감염성 낭포환자에서는 계속적 항생제 투여였는데, 저자들은 이와같은 경우 직경이 작은 카테타로 국소마취하에 경피적 배농술을 시행하여 그 치료효과와 부작용을 알아 보고자 본 연구를 시행하였다. 방법 : 1주 이상의 항생제를 포함한 내과적 치료에 반응이 없고, 공동의 직경이 6cm 이상인 만성적 기저질환을 가지는 폐농양 환자 9에와 감염성 낭포환자 3예에서 흉부 단순촬영과 흉부 전산화 단층촬영 후 투시하에 seldinger 방법을 사용하여 8.3~12.3 Fr의 카테타를 삽입 후 배농시키면서 임상경과를 관찰하였다. 결과 : 카테타 삽입 후 농흉이 발생한, 폐암과 동반된 1예를 제외한 8예의 폐농양과 3예의 감염성 낭포에서 경피적 배농술 후 임상적 호전을 보였다. 배농 후 평균 1.9일 내 해열되었고, 평균 배농기간은 9.9일이였다. 7예에서 퇴원 후 1~7개월간 외래 관찰되었으며, 재발 등의 문제는 없었다. 결론 : 내과적 치료에 반응이 없는 거대 폐암 환자에게 경피적 배농술은 효과적이고 안전한 방법이므로, 수술보다 우선적으로 고려되어야 하겠다. 그러나 감염성 낭포환자에 대한 경피적 배농술은 본 연구의 결과만으로 내과적 치료보다 더 안전하고 효과적이라고 할 수 없으므로 더 많은 연구가 있어야 하겠다.

• Tuberculosis and Respiratory Diseases
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• 제66권5호
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• pp.390-395
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• 2009

기관지폐쇄에 의한 폐농양 혹은 공동성 병변에 발생한 암성 농양은 임상 양상 및 방사선학적 소견이 흡인성 폐농양과 흡사하여 감별이 어려워서 폐암을 조기 진단할 수 있는 기회를 놓치기 쉽다. 따라서 항생제에 대한 반응이 뚜렷하지 않거나 선행 요인이 없고 비전형적인 위치에 발생한 폐농양의 경우 악성 병변의 동반 가능성을 염두에 두고 적극적인 검사가 필요하다. 저자들은 발열, 기침, 혈담, 호흡곤란을 주소로 내원하여 폐농양 의심하에 항생제 치료에도 불구하고 병변이 악화된 67세 남자 환자에서 간세침흡인생검을 통해 다발 전이성 농양을 일으킨 편평상피세포암성 농양으로 진단된 예가 있어 문헌 고찰과 함께 보고하는 바이다.

• Journal of Chest Surgery
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• 제2권1호
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• pp.3-12
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• 1969

Prior to availability of antibiotics, lung abscess has been recognized as one of the most serious pulmonary disease, and despite of diminished morbidity and mortality rate with the advent of antibiotics and development of better technique in the fields of surgery on pulmonary disease it continues to be a virulent form of pulmonary supuration. It is the purpose of this paper to present a clinical review of 115 lung abscess treated by surgically at "The National Medical Center" during past 9 years. 1. The most common age of occurrence is between the age of 30 and 50, and 105 cases were male and 31 cases occurred in female. 2. Numerous etiological factors may play a role in the formation of a pulmonary abscess; aspiration in 36 patients of which 2 patients had diabetes, 54 patients had preceding URI or pneumonia, and 5 patients followed liver abscess, one of which in hematogenous route. In 20 patients, no predisposing factor could be determined- 3. Clubbing digits were presented in 26 of 1315 patients suggesting chronicity of the disease, and gastric ulcer were combined in 3 of 136 patints. 4. Apparently the onset was insidious, and the progress was masked by indiscriminate administration of antibiotics for URI and TB remedies under impression of pul. tbc. Previous TB treatments were done in 56.%[76 cases] for one week to two years and administration of antibiotics in 51 cases. 5. 89 cases were on tbe right and 2t5 cascs were on the left side. 51 cases of pneumonectomy and 8 of open drainage, of which 4 of Monaldi procedure, were made and operative mortality rate was 5.2%. Numerous complications such as 8 of empyema, 4 of each bleeding and atelectasis, 2 of BPF, 1 of esophageal fistula and one of pneumothorax which were responded well to prolonged treatment with good results, were obtained. 6. The incidence of Klebsiella and Pseudomonas were increased recently. In these results, we submit the surgery should be performed if the conservative therapy had failed. The resection was most favorable operation for pulmonary abscess though drainage procedure may be of value in certain patients with grave systemic menifestations. In chronic long standing abscess, more complications and high mortality rate were assumable although the prognosis has been improved with the advent of antibiotics, the development of improved surgical technique and complete preoperative care.