• Journal of Chest Surgery
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• v.27 no.7
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• pp.587-597
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• 1994

To study the recovery pattern of pulmonary function after decortication, the author performed serial pulmonary function tests using spirometry before and at lst., 3rd., 4th. week, lst., 3rd., 6th. month and 1st. year in 36 patients who underwent decortication from January 1989 to September 1991 at the Department of Thoracic and Cardiovascular Surgery, Pusan National University Hospital, Pusan, Korea. Patients were divided into 3 groups by the degree of compression of lung parenchyme. Group I was classified below 20%, Group II between 21 to 40%, Group III above 41%. Their serial changes of pulmonary function test were compared. The obtained results were as follows; 1. Maximal voluntary ventilation was recovered in 1st post perative week and even greater improvement was noted in group III in which ratio to 44 % of the preoperative value. 2. Vital capacity reached nearly to preoperative values in 3rd postoperative week and had increased much further to 26 % above the preoperative figure in group II. 3. Forced expiratory volume in 1 second returned rather slowly in 3rd-4th postoperative week and the mean VC was improved more higher in group II than the other groups following decorti cation. 4. There was an greatest improvement over all tests[MW, VC, FEV1] in 2nd decade which ratios to preoperative value were 34, 25 and 22 % respectively.

• Journal of Korean Physical Therapy Science
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• v.23 no.1
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• pp.9-17
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• 2016

Background and Purpose : Effects of smokers's jogging exercises on oxygen uptake, ventilation, heart rate, and vital-capacity of normal adults have not been studied in details on. In this study, people that had completed the established jogging exercises was selected for the study. We could examine the effects of imposed jogging in smokers who might be considered by an experienced physical therapist to be well practiced and proficient in this exercises. Subjects and Methods : A total number of 24 young healthy subjects participated in a randomized crossover controlled study and completed the study. The subjects of this study were divided into jogging and controlled groups which were composed 14 people respectively. The members of exercise group had jogging exercises 50 minutes a day, five times a week, for 5 weeks in same conditions, otherwise controlled group did not. Results : The results of this study were as follows. The jogging group demonstrated significant increases in cardiopulmonary function, vital-capacity and exercise capacity, compared with control group, which demonstrated no change in baseline measurements of 5 weeks. Conclusion : Jogging exercises can increase cardiopulmonary function in people after they have undergone successful PA. These results suggested that it was improved on cardiopulmonary function and lung capacity, since jogging exercise had. The results of this study could be applied for valuable criterion cardiopulmonary function. It is necessary to selects in various groups of the purpose of enhancing confidence in of this research.

• Physical Therapy Rehabilitation Science
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• v.10 no.3
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• pp.289-296
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• 2021

Objective: The purpose of this study was to changes in respiratory function due to differences in mask blocking grade, and effects on cardiovascular function during aerobic exercise. Design: Comparative study using paired t-test and analysis of variance measures. Methods: Male and female subjects were randomly divided into 4 groups according to mask blocking grade and measured respiratory functions before and after wearing the mask using spirometers, and their cardiovascular capabilities were measured using pulse oxygen meters and blood pressure meters before and after running for 10 minutes wearing mask. Used paired t-test, one-way ANOVA and Bonferroni post-test to compare the differences according to the mask blocking grade. Results: The experimental results verified that three groups except for the Non-mask group had a significant reduction in all values of FVC, FEV1, MVV, and PEF after wearing a mask compared to those before wearing a mask(p<0.05). Also a significant difference in cardiovascular functions was also observed after aerobic exercises wearing mask in all groups and there was a significant difference between all four groups(p<0.05). Conclusions: Lung patients with poor breathing, elderly and children with poor lung function, and professional groups who need to wear masks and take high-intensity work or aerobic movements are encouraged to take frequent breaks in advance, wear masks and social distancing at moderate and low levels.

• Journal of Chest Surgery
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• v.50 no.5
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• pp.399-402
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• 2017

We report the case of a patient with penetrating chest trauma (right chest) who had undergone a left pneumonectomy due to pulmonary tuberculosis 24 years ago. We performed an emergent thoracotomy, finding an opening of the penetrating wound in a lower-lobe basal segment of the right lung. A stapled tractotomy was performed along the tract. Bleeding control and air-leakage control was done easily and rapidly. The patient was discharged without any complications on the seventh day of admission. Tractotomy can be a good option for treating penetrating lung injuries in patients with limited lung function who need emergent surgery.

• Journal of Chest Surgery
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• v.35 no.1
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• pp.64-67
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• 2002

Eisenmenger's syndrome is the disease of right to left shunt developing from the increased pulmonary vascular resistance caused by excessive pulmonary blood flow in patients with abnormal connections of systemic to pulmonary blood passage. The heart-lung transplantation was the only curative method in early transplantation period, but good results after bilateral lung transplantation have been reported as the fact that right heart function improved by only lung transplantation. We successfully carried out bilateral sequential single lung transplantation in a 34-year-old female patient with Eisenmenger's syndrome with large PDA. We report this case with a brief review of the literature.

• Journal of Chest Surgery
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• v.2 no.1
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• pp.25-40
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• 1969

Lung homotransplantation was performed in 15 pairs of dog. Methotrexate and R.E.S. blocking were used to prolong the survival time. Details of handling the transplant, operative technique and management of the recipient were discussed and following results were obtained: 1]. 7 dogs out of 15 dogs of homotransplantation of lung were survived beyond 3 days. In the group of dogs treated with methotrexate, the average survival was 8.5 days, and in the group of dogs treated with R.E.S. blocking, the average survial was 9.7 days with longest survival of 17 days. 2]. The causes of immediate postoperative death in homotransplantation of dogs were lung edema and disruption of bronchial anastomosis. 3]. The main causes of death in successful homotransplantation dogs which were survived beyond 3 days were infection of lung parenchyma and bronchial necrosis rather than the occurence of graft rejection. 4]. Graft rejection was not revealed even after 7 days of operation in the group treated with methotrexate as well as in the group treated with R. E.S. blocking. This finding made it suggest that the R. E.S. blocking may be effective to control the rejection reaction. 5]. Even though the pulmonary function of transplanted lung was revealed the evidence of severe impairment immediate after operation by bronchospirometry, it was increased gradually and 10 days after operation the minute ventilation and oxygen uptake were decreased 8%, 13% respectively less than pre-operative one.

• BMB Reports
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• v.54 no.8
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• pp.425-430
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• 2021

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces coronavirus disease 2019 (COVID-19) and may increase the risk of adverse outcomes in lung cancer patients. In this study, we investigated the expression and function of mucin 1 (MUC1) after SARS-CoV-2 infection in the lung epithelial cancer cell line Calu-3. MUC1 is a major constituent of the mucus layer in the respiratory tract and contributes to pathogen defense. SARS-CoV-2 infection induced MUC1 C-terminal subunit (MUC1-C) expression in a STAT3 activation-dependent manner. Inhibition of MUC1-C signaling increased apoptosis-related protein levels and reduced proliferation-related protein levels; however, SARS-CoV-2 replication was not affected. Together, these results suggest that increased MUC1-C expression in response to SARS-CoV-2 infection may trigger the growth of lung cancer cells, and COVID-19 may be a risk factor for lung cancer patients.

• Communications for Statistical Applications and Methods
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• v.28 no.2
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• pp.119-134
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• 2021

Lung cancer is one of the leading causes of cancer deaths in the world. Investigation of mortality rates is pivotal to adequately understand the determinants causing this disease, allocate public health resources, and apply different control measures. Our study aims to analyze and forecast age-specific US lung cancer mortality trends. We report functions of mortality rates for different age groups by incorporating functional principal component analysis to understand the underlying mortality trend with respect to time. The mortality rates of lung cancer have been higher in men than in women. These rates have been decreasing for all age groups since 1990 in men. The same pattern is observed for women since 2000 except for the age group 85 and above. No significant changes in mortality rates in lower age groups have been reported for both gender. Lung cancer mortality rates for males are relatively higher than females. Ten-year predictions of mortality rates depict a continuous decline for both gender with no apparent change for lower age groups (below 40).

• The Journal of Internal Korean Medicine
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• v.10 no.1
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• pp.105-123
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• 1989

Yuk Gi (六氣) in oriental medicine have influence on the body and, the body which adapt itself to the change of Yuk Gi, can maintain the activity of life, so five vital organs of the body have relation to Yuk Gi. The relation between Lung and Jo (燥) is well described from Whang Jae Nai Kyung (黃帝內經), the oldest book in oriental medicine, to the old books of Chung (淸) dynasty and modern documents. By the way, when autumn has come and the environment become dry, clear and mild ability of lung is losed. It's because dryness evil (燥邪) occured the trouble of Lung. The following results were obtained according to these facts which is considreed peviodically and bibliographically. 1. According to flourishing the functional activities of dryness (燥氣), as reducing the functional activities of water (水氣) of upper portion of the body cavity (上焦), Kidny Water (腎水) is not nutrited and Fire-Heat (火熱) is activiting, which is evoking the disease of Lung. 2. In the disease of Lung, there are many diseases because of dryness evil (燥邪), thinking that, which methods of treatment are the principal one of 'Clear up the lung and moisten dryness (淸肺潤煥)'. I found that Lung and Jo (燥) have the relation of intimacy. 3. Creating the vital essence of the kidney (腎水) to the functional activities of the lung (肺氣) is in prosperous condition, the functional activities of fire (火氣) stabilize the function of Lung become normal condition which wear said in the literary.

• Tuberculosis and Respiratory Diseases
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• v.63 no.4
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• pp.323-330
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• 2007