• Korean Journal of Applied Biomechanics
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• v.15 no.2
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• pp.93-102
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• 2005

The purpose of this study was to examine the effect of step length on the joint moment. The subjects were 4 undergraduate and graduate students in their 20s with normal legs. The subjects were individually tested by the running timer at the walking speed of 0.67m/s, 134m/s, and 2.46m/s. The step length was regulated to -10% of normal, normal and +10% of normal step length using foot print. The walking performances of each subjects were filmed using a high speed video camera. The raw data were analyzed by LabVIEW Graphical Program and these data were analyzed by ANOVAs and Scheffe. The results of this study were as follows: The maximum dorsiflexion moment of the ankle joint increased as the step length increased only at the fast walking speed. Although there wasn't significant difference shown in the plantar flexion moment, regular pattern in the plantar flexion moment which increased as the step length increased was found. The first maximum extension moment of the knee joint increased only at the normal walking speed, but there appeared no significant difference in the maximum flexion and second extension moment. The maximum extension moment of the hip joint increased at the normal and fast walking speed. Although there wasn't significant difference, regular pattern in flexion moment which increased as the step length increased was found.

• Korean Journal of Applied Biomechanics
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• v.13 no.3
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• pp.163-180
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• 2003

This paper aims at collecting the guantitative data of kenematic variables by analysing the gait patterns of the normal adult men and the handicapped. The gait motions were taped with 4 video cameras, the cinematographic analyses were performed by the DLT technique of three dimensional image treatment. The following results were obtained in the analysis of the variables: 1. The ratio of stance time and swing time did not show any significant difference in the groups of the normal men and the handicapped when both foot of the former and the right feet of the latter were compared. The stride peeriod time of these two groups were 1.12 and 1.11 second, respectively. 2. In the handicapped group, the step width was wider, the step length and stride length were shorter, and especially, the step length of the right foot was shorter, 3. The small vertical displacement of left toes of the handicapped group showed that the heal contact and the left midstance are almost simultaneous. 4. The two groups have almost the same horizontal displacement of the center of gravity and the same vertical rate of extension. In view of the velocity of the center of gravity the normal adults showed the constant speed of movement. However, the handicapped adults were reduced from the right midstance to the right toe-off. 5. The handicapped showed prominently low angle on the left toe-off in the ankle joint angle, they also had the tendency to walk in the patterns of extended knee in the knee joint angle. Both the handicapped and the normal had the hyperextension on the toe-off in the hip joint angle. In the back and front angle of body, both showed the slightly back-sided walking positions. 6. Both groups had the abduction of both feet in foot placement angle, but the handicapped did not show serious abduction of left midstance.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.2
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• pp.76-81
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• 2010

Purpose: This study examined how the degrees of muscle activity of Rectus Femoris and Tibialis Anterior during the four phases of walking vary according to three different treadmill slopes of $0^0$, $7^0$, and $15^0$. Methods: Subjects were 14 randomly selected healthy students attending G University in Seoul, Korea who had never had articular problems with lower limb and had no difficulties walking at the time of study. Results: 1) With respect to Rectus Femoris, in every phase of both forward and backward walking, there were significant differences among all of the slope degrees (p <.05), while the activity increased with increased slope degrees in every phase of backward walking. 2) For Tibialis Anterior, only in P2 and P3 of both forward and backward walking there were significant differences in every slope (p <.05). Conclusion: Both Rectus Femoris and Tibialis Anterior were found to be more active during backward walking compared to backward walking. In addition, the activity degree of Rectus Femoris was high between the early part of two foot support phase and the early part of one foot support phase, whereas that of Tibialis Anterior was high between the early part of one foot support phase and the latter part of both foot support phase.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.1207-1210
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• 2004

As many humans age, degenerative lumbar spinal stenosis (DLSS) becomes a major cause of lower limb discomfort and disability. By surgical treatment method of DLSS, the existing surgical treatment methods using internal fixation have showed degeneration changes of an adjacent vertebrae and loss of lumbar spine lordosis-kyphosis due to eliminating a motion. For solving the problems of internal fixation, a novel interspinous spacer has been developed to treat DLSS by surgical treatment method. In this study, we evaluated the biomechanical effects of the interspinous spacer on the kinematics of the porcine lumbar spine before and after insertion of the implant. For this purpose, a device that is capable of measuring 3-D motions were built based on direct linear transformation (DLT) algorithm written with MATLAB program. Results showed that in extension, a change of the mean angle between the intact and the implanted specimens at L4-L5 was 1.87 degree difference and the implant reduced the extension range of motion of the L4-L5 (p＆lt;0.05). But the range of motion in flexion, axial rotation and lateral bending at the adjacent segments was not statistically affected by the implant. In conclusion, we thought that interspinous spacer may have remedical value for DLSS by flexing human lumbar spine.

• Tuberculosis and Respiratory Diseases
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• v.51 no.3
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• pp.270-274
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• 2001

A functional upper airway obstruction due to a vocal cord dysfunction(VCD) is characterized by a paradoxical adduction of the vocal cords throughout the respiratory cycle with no obvious organic cause for the obstruction. It commonly occurs paroxysmally and imitates acute asthmatic attacks, often in patients with coexisting asthma. They present with episodes of dyspnea associated with inspiratory wheezing that persists despite conventional asthma treatment and a flattening of the inspiratory limb of the flow-volume curve ; an adduction of the vocal cord during inspiration. Failure to recognize concurrent vocal cord dysfunction and asthma has led not only to the excessive use of bronchodilators and corticosteroids, but also to intubation and tracheostomy. Here, we report a case of coexistent obstructive pulmonary disease and functional upper airway obstruction due to a vocal cord dysfunction where a bronchoscopy showed a paradoxical vocal cord motion and typical features of a variable extrathoracic obstruction and a lower airway obstruction on the Flow-volume loop during a symptomatic period.

• Journal of Nutrition and Health
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• v.15 no.4
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• pp.258-267
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• 1982

This study was performed to investigate the effect of different levels of protein and iron in the diet upon Fe, Cu and Zn metabolism in rat during four weeks of growing period. Forty-five male weanling rats of Sprague-Dawley strain weighing $68.5{\pm}1.1g$ were divided into 9 groups and each group was given with one of the 9 different kinds of diets for four weeks. The three dietary protein levels used were 5, 20 and 40% and Fe levels 0, 35, and 350 ppms. The results obtained were summarized as following ; 1) Food intake and body weight gain in 20%(SP) and 40%(HP) dietary protein groups tended to be significantly higher than 5%(LP) protein groups. Protein efficiency ratio (PER) was higher in LP groups than in HP and SP groups. With dietary Fe levels, there were no significant differences among groups in food intake, body weight gain, and PER. 2) In LP groups, the Fe concentrations in liver, kidney, and hind limb muscle were higher than in SP and HP groups. Regarding with dietary protein levels, the liver Cu concentrations in LP groups were slightly higher, but the liver Zn concentrations were lower in LP groups. The Fe concentrations in liver and kidney tended to decrease with decrease in dietary Fe levels, but Cu and Zn concentrations showed no consistent tendency with dietary Fe levels. 3) The Fe, Cu and Zn concentrations in serum were not different from dietary treatments except that the serum Fe concentrations increased slightly in LP groups. 4) The Fe and Cu concentrations in urine tended to be higher in HP groups. Fecal Cu and Zn concentrations showed no significant differences in dietary protein or Fe levels, but the Fe concentrations tended to increase with increase in dietary Fe levels.

• Archives of Plastic Surgery
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• v.36 no.3
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• pp.299-305
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• 2009

Purpose: Recently, the incidence of malignant melanoma has been steadily increasing. Malignant melanoma is already known to have poorer prognosis than other primary skin cancers. Despite the poor prognosis, it is relatively less known to the public so that a number of patients visit hospital carrying advanced stage tumor. Yet, extensive study about malignant melanoma is currently insufficient, and specific guidelines and statistical figures in Korea are almost inexistent. Therefore, authors reviewed patients with malignant melanoma who have visited our hospital for last 14 years. Methods: Between January 1994 and January 2008, 62 patients were diagnosed with malignant melanoma at our hospital. A retrospective study was performed with data from patients' charts and biopsy results. Annual incidence, mean age of onset, gender, tumor location, tumor thickness, pathologic ulceration, clinicopathologic subtype, and clinical AJCC stage were evaluated. Analysis of factors associated with survival were performed using the Cox proportional hazard model. Kaplan - Meier method was used to generate survival curves. Results: Clinicopathologic features of 62 patients (32 male, 30 female) with average age of 57 years were evaluated. Most lesions were found in lower limb, and the most common subtype was acral lentiginous melanoma. We could also find that age, tumor thickness, and clinical stage were the only significant prognostic factors. Conclusion: Clinicopathologic features of malignant melanoma were analyzed in this study, but the result is not ready to be generalized because the number of cases is too small. Further study must be performed to report clinical guidelines for prognosis and treatment for malignant melanoma patients in Korea.

• Journal of the Korean Society of Physical Medicine
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• v.3 no.2
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• pp.97-102
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• 2008

Purpose : The purpose of this study was to find the effect of foot bath on blood pressure(BP) following treadmill exercise. Methode : Subject of study were forty healthy males without any cardiovascular, musculoskeletal, and neurologic diseases. Following twenty minutes walking at a speed of 5m/s on the treadmill, ten twenty subjects in experimental group received foot bath, on the dominant lower limb while sitting in chair. Foot bath was applied to the level of the lateral and medial malleoli keeping the temperature of the paraffin bath at $40{\pm}0.5^{\circ}C$. Twenty subjects in control group took a rest sitting in chair in a comfortable position. BP was measured in right brachial artery. BP was measured five times(before exercise, immediately after exercise, 5 minutes, 10 minutes, and fifteen minutes after exercise). Results : The study showed that for diastolic blood pressure, there was no significant difference between the experimental and the control group. However, systolic blood pressure(SBP) increased significantly after exercise compared with SBP before exercise (p<.05). In addition, SBP in five minutes after exercise decreased significantly compared with SBP in immediately after exercise (p<.05). On the other hand, the control group had significant difference between SBP measured before exercise and SBP measured at the other measure time (p<.05). In five minutes after exercise, SBP in experimental group had significant difference with SBP in control group (p<.05). Similarly, in ten and fifteen minutes after exercise, SBP in experimental group had significantly difference with SBP in control group (p<.05). Conclusion : Consequently it was confirmed that when foot bath was applied, the increased BP induced by the exercise returned to normal range rapidly.

• Journal of the Korean Society of Physical Medicine
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• v.13 no.3
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• pp.39-47
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• 2018

PURPOSE: The purpose of this investigation was to conduct a systemic review of studies that examine the effects of strengthening exercise on gait ability and GMFM in children with cerebral palsy and propose a standard for cerebral palsy therapy based on a meta-analysis of the studies. METHODS: An extensive literature search was conducted using databases including the KISS (Korean studies Information Service System), RISS, DBpia, PubMed and ScienceDirect, with the following search terms: 'Strengthening Exercise,' 'Resistance Exercise,' 'Gait ability,' 'GMFM' or 'cerebral palsy'. RESULTS: Eleven studies were included in this review and the duration of the intervention varied from 5 to 24 weeks. The number of application per week was mostly 2-3 times, while 5 intervention per week was adopted in a few cases. The total number of intervention applied varied from 18 to 36 and the respective effect sizes of GMFM on crawling and sitting were very high (1.075 and .881) while those of GMFM on standing and walking were very low(.206 and .125). The effect size was for gait speed was only .221. CONCLUSION: Trunk exercise and lower limb exercise effectively improved GMFM in children with cerebral palsy, resulting in improved outcomes in sitting and crawling. The results of this study will be useful for designing evidencebased cerebral palsy therapy programs.

• The Korean Journal of Pain
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• v.31 no.1
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• pp.10-15
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• 2018

Background: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the activities of the primary afferent fibers at the dorsal horn. Methods: In experiment 1, 45 rats were assigned to Control, Allo small-dose (0.16 mg/kg), and Allo large-dose (1.6 mg/kg) groups (n = 15 in each). The weight bearing and mechanical withdrawal thresholds of the hind limb were measured before and at 2, 24, 48, and 168 h after Brennan's surgery. In experiment 2, 16 rats were assigned to Control and Allo (0.16 mg/kg) groups (n = 8 in each). The degree of spontaneous pain was measured using the grimace scale after the surgery. Activities of the primary afferent fibers in the spinal cord (L6) were evaluated using immunohistochemical staining. Results: In experiment 1, the withdrawal threshold of the Allo small-dose group was significantly higher than that of the Control group at 2 h after surgery. Intergroup differences in weight bearing were not significant. In experiment 2, intergroup differences in the grimace scale scores were not significant. Substance P release in the Allo (0.16 mg/kg) group was significantly lower than that in the Control group. Conclusions: Systemic administration of Allo inhibited mechanical allodynia and activities of the primary afferent fibers at the dorsal horn in a rat postoperative pain model. Allo was proposed as a candidate for postoperative pain management.