• Annals of Clinical Neurophysiology
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• v.6 no.2
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• pp.85-91
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• 2004

Background: Needle electromyography (EMG) and motor evoked potential (MEP) of the genioglossus (tongue) are difficult to perform in evaluations of the craniobulbar region in amyotrophic lateral sclerosis (ALS). Therefore, we investigated the yields of needle EMG and MEP recorded from the upper trapezius, since it receives innervation from the lower medulla and upper cervical cord. Methods: Needle EMG and MEP of the upper trapezius were obtained in 17 consecutive ALS patients. The needle EMG parameters recorded included abnormal spontaneous activity and motor unit action potential (MUAP) morphology. An upper motor neuron (UMN) lesion was presumed when either response to cortical stimulation was absent, or the central conduction time was delayed (>mean+2SD). Results: Of the five patients with bulbar-onset ALS, four had abnormalities in the upper trapezius and four in the tongue by needle EMG. In contrast, of the 12 patients with limb-onset ALS, 11 had abnormalities in the upper trapezius, and only five in the tongue. When MEP was performed, it was found that three of the five patients with bulbar symptoms and three of the six patients with isolated limb involvement had abnormal MEP findings. Conclusions: Electrophysiological studies of the upper trapezius are more sensitive those of the tongue in patients without bulbar symptoms. Thus, needle EMG and MEP of the upper trapezius are alternative tools for assessing bulbar and rostral neuraxial involvement in the diagnosis of ALS.

• Nutritional Sciences
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• v.4 no.1
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• pp.34-38
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• 2001

The purpose of this study was to compare the energy expenditure of normal-weight and overweight Korean middle-aged women (40-60 yr). Middle-aged oveweight ($BMI\;{\geq}\;25$, n= 20) and normal-weight women were ($BMI\;{\leq}\;23$, n = 20) were recruited in Seoul. Anthropometric measurements, body composition, energy intake, daily activity time, and energy costs of some daily activities were measured. Energy expenditure at rest and while reading the newspaper, washing dishes, mopping the floor, and walking on a treadmill at 1.0, 2.0, 3.5mph were measured by indirect calorimeter and total daily energy expenditure was estimated by summation of energy costs of different activities. The overweight group had significantly higher values of body weight, triceps skinfold thickness, thigh circumference, waist circumference, hip circumference, BMI, WTR, WHR, body surface area, percentage body fat, fat mass, fat free mass (FFM), and muscle mass compared to normal-weight group. The energy intakes of both groups were close to RDA and other nutrient intake status was also satisfactory. There were no significant differences in intakes of energy and nutrients between the two groups. Overweight subjects showed lower energy expenditure per kg body weight for reading the newspaper, washing dishes and mopping the floor, and walking on a treadmill at 2.0 and 3.5 mph, however, energy expenditure per kg FFM did not differ between the two groups. Daily energy expenditure for all activities was significantly higher in the overweight compared to the normal-weight group due to higher body weight. Both overweight and normal-weight groups showed negative energy balance between energy intake and energy expenditure, and there was no significant difference in energy balance between the two roups. Total daily energy expenditure correlated highly with FFM and body surface area. The result of present study does not offer an explanation on the energy imbalance and weight gain of overweight women.

• Journal of the Korean Applied Science and Technology
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• v.35 no.3
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• pp.940-947
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• 2018

The purpose of this study was to obtain data to support applied motions of bench press and to provide basic data for the efficient execution of the exercise by analyzing muscular activation through measuring electromyogram of pectoralis major and erector spinae when flat bench pressing with feet on the ground versus feet on the bench. For this study, 4 amateur bodybuilders and 2 health trainers were chosen as subjects. Surface electrodes were attached on the measuring muscles; pectoralis major and erector spinae. Motion phases were defined for the flat bench press and each subject, with a 10RM load, performed a set with feet on the ground and another set with feet on the bench. Data was analyzed in SPSS 20.0 and the following results were obtained. The placement of the feet did not affect the muscular activation of the pectoralis major during the flat bench press. however, the muscular activation of the erector spinae was different between the two positions.

• Journal of the Korea Safety Management & Science
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• v.11 no.2
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• pp.103-110
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• 2009

The purpose of this study is to suggest a proper tread of stairs using kinematic factors and moments of the lower-limb joints in the stair decent with the 3 different treads with boimechanical method in ergonomics. 9 subjects (body masses; $59.41{\pm}7.49$, $64.03{\pm}6.65$, $67.26:{\pm}7.58$, heights; $160.50{\pm}6.35$ ages; $31.22{\pm}2.99$; parity; $1.67{\pm}0.71$) participated in three experiments that were divided by physiological symptoms (the early (0-15 weeks), middle (16-27 weeks) and last (18-39 weeks). and they walked at self-selected pace on 4 staircases 3 trials. As extending the pregnancy period, cadence was shorter but cycle time were longer more and more. As extending treads of stair decent during pregnancy, speed, stride lengths and cycle time were increased. As extending the treads of stair decent, hip and ankle moments increased but knee moments decreased in sagittal plane. There were increasing or decreasing of moments by means of treads. These changes may account for relation between the treads of stair and moments in pregnant women. The main changes of pregnant women were joint moments and kinematic factors during pregnancy period because pregnancy makes them physical changes. It is possible that joints have connection with compensation each other to maximize stability and to control gait motion. In conclusion, we suggest that the tread of stair is longer than 26cm tread. and exercise programs to improve muscle activity were necessary where joint moments were small.

• Journal of the Korean Society of Clothing and Textiles
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• v.35 no.9
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• pp.1039-1048
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• 2011

This research develops a basic design structure for scuba diving wetsuits suitable for the shape of Korean men in their 30's as well as enhances the reduction rate for underwater activity. The clothing pressure and fitness tests were performed using four different types of body suits. The usable data of the tests were coded for further statistical analysis that includes one way-ANOVA test and S-N-K Multiple Range Test by using SPSSWIN 17.0. An analysis of the results shows: (1) The results of the clothing pressure test (using a dummy) indicated that the larger the reduction rate, the stronger the clothing pressure gets (with an exception on the knee area). It has great impact on clothing pressure with regards to the different body parts. The different reduction rates should be applied to body parts accordingly. (2) In the case of test subjects, the overall mean values of the clothing pressure were lower than the ones with the dummy (attributable to the cushion function of body skin and muscle as well as the high stretch of the fabric). (3) In evaluating the subjective fit test of four types of body suits, a statistically significant difference was found in the relation between pattern reduction rates and all parts of the body. It was revealed that the reduction rate of 'B' pattern (X: 4%, Y: 3%) was the most suitable pattern and the 'B' pattern scored highest in the motion functional fit test performed by a test subject.

• The Journal of Korean Physical Therapy
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• v.27 no.4
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• pp.228-233
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• 2015

Purpose: Gait is the most basic element when evaluating the quality of life with activities of daily living under ordinary life circumstances. Symmetrical use of the lower extremities requires complicated coordination of all limbs. Thus, this study examined asymmetry of muscle activity quadriceps femoris and tibialis anterior as a baseline for training during over-ground walking and stair walking of stroke patients. Methods: Subjects were 14 stroke patients included as one experimental group. Gait speed used in this study was determined by the subject. Low extremity paretic and non-paretic EMG was compared using the surface EMG system. Results: The low extremity EMG difference was statistically significant during over-ground walking and stair walking (p<0.05). The result of low extremity EMG substituted symmetry ratio formula was compared to EMG symmetry ratio in both legs during over-ground walking and stair walking. The average symmetry ratio of quadriceps femoris during over-ground walking was 0.65, and average symmetry ratio of quadriceps femoris during stair walking was 0.47, with significant difference (p<0.05). Conclusion: EMG data was higher in stair walking than over-ground walking. However, in the comparison of symmetry ratio, asymmetric EMG of quadriceps femoris was significantly increased during stair walking. These findings suggested that application of stair walking for strengthening of both legs can be positive, but the key factor is maintaining asymmetrical posture of both legs. Therefore, physical therapists should make an effort to reduce asymmetry of quadriceps femoris power during stair walking by stroke patients.

• Biomolecules & Therapeutics
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• v.28 no.4
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• pp.328-336
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• 2020

Diabetes mellitus affects the colonic motility developing gastrointestinal symptoms, such as constipation. The aim of the study was to examine the role of intracellular signaling pathways contributing to colonic dysmotility in diabetes mellitus. To generate diabetes mellitus, the rats were injected by a single high dose of streptozotocin (65 mg/kg) intraperitoneally. The proximal colons from both normal and diabetic rats were contracted by applying an electrical field stimulation with pulse voltage of 40 V in amplitude and pulse duration of 1 ms at frequencies of 1, 2, 4, and 6 Hz. The muscle strips from both normal rats and rats with diabetes mellitus were pretreated with different antagonists and inhibitors. Rats with diabetes mellitus had lower motility than the control group. There were significant differences in the percentage of inhibition of contraction between normal rats and rats with diabetes mellitus after the incubation of tetrodotoxin (neuronal blocker), atropine (muscarinic receptor antagonist), prazosin (α₁ adrenergic receptor antagonist), DPCPX (adenosine A1 receptor antagonist), verapamil (L-type Ca²⁺ channel blocker), U73122 (PLC inhibitor), ML-9 (MLCK inhibitor), udenafil (PDE₅ inhibitor), and methylene blue (guanylate cyclase inhibitor). The protein expression of p-MLC and PDE₅ were decreased in the diabetic group compared to the normal group. These results showed that the reduced colonic contractility resulted from the impaired neuronal conduction and decreased muscarinic receptor sensitivity, which resulted in decreased phosphorylation of MLC via MLCK, and cGMP activity through PDE₅.

• The Journal of Korean Physical Therapy
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• v.25 no.3
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• pp.126-131
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• 2013

This case report described a single case of adult stoke patient due to Moyamoya disease through long-term follow-up observation, which included his demographics, brain images, and change of motor function and functional activities. The subject was the 54-year-old male diagnosed with left hemiparesis from a stroke due to multifocal encephalomalacia in both hemispheres. At the time of the stroke attack, he took brain surgery intervention including external ventricular drain. Physical and occupational therapy for stroke rehabilitation were admitted including muscle strengthening exercises, functional activity/ADL training, neurofacilitative techniques with bobath or proprioceptive neuromuscular facilitation concepts, and compensatory strategy. Patient's MRI showed that right frontal lobe, right peri-ventricular area, left parietal, and left occipital lobes were damaged, and MRA showed that abnormal collateral vessel was richly developed in both hemispheres by occlusion of proximal internal carotid arteries in both sides. His motor strength was improved from poor to good grade in all of upper and lower limb motions, that MBC was improved from stage 1 to stage 5. In FAC and barthel index, at the initial evaluation, he could not perform any functional movement, but his FAC and barthel index were on 3 and 14 points at present, respectively. During long-term follow-up for approximately 4 years, the subject's functional motor ability was improved, as similar with recovery progression of usual stroke patient. We believe that this single case report will provide clinical information and concern regarding Moyamoya disease with physical therapist, in terms of such as epidemiology, pathogenesis, diagnostic procedures, clinical features, recovery process, and prognosis.

• Korean Journal of Applied Biomechanics
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• v.19 no.4
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• pp.647-653
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• 2009

The purpose of this study was to investigate the differences between female and male ballet dancers in anterior cruciate ligament injury risk factors during the box drop landing task. Nine female and nine male collegiate ballet dancers participated in this study. Kinematic and ground reaction data were collected and combined with inverse dynamics to estimate the knee extensor and abductor moment. EMG data from the biceps femoris and rectus femoris were used to estimate the ratio of quadriceps-hamstrings muscle activity. No gender differences in anterior cruciate ligament injury risk factors were found during the box drop landing task. A significant relationship was found between female and male ballet dancers in the knee flexion angle.

• Korean Journal of Veterinary Research
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• v.27 no.1
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• pp.27-34
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• 1987

To verify the direct effects of the thyroid hormone ($T_3$) on the rabbit heart, $T_3$-Tyrode solution in vitro was perfused on the normal atrial muscles and enzymatically isolated ventricular myocytes of the rabbit. All the experimental procedures were conducted at $35^{\circ}C$ and the same procedures were repeated after Ca. 120 minutes from the beginning of $T_3$-Tyrode perfusion. Compared to the state between the normal Tyrode solution and $T_3$-Tyrode solution, results were observed on the same cells by electrophysiological methods (conventional intracellular recording and whole cell patch clamping) as soon as possible. The results obtained were as follows : 1. Action potential duration (APD) on the left atrial muscle was reduced under the perfusion of $T_3$-Tyrode. 2. Absolute refractory Period was shortened by $T_3$-Tryrode perfusion. (117 msec./114 msec., 90 msec./78 msec.) 3. Maximal Ca currents ($i_{Ca}$) were decreased in single: ventricular myocytes under the $T_3$-Tyrode (2.98 nA) than under the normal Tyrode (6.65 nA) 4. On I-V relation, reversal potential was shifted to lower membrane potential and membrane potential showing maximal $i_{Ca}$was lowered from +10mV to -20mV by $T_3$ effect. 5. Above results were likely to explain that tachycardia in the hyperthyroid state was caused in part by the reduced repolarization phase and the reduced refractory period due to the decrease of the Ca current.