• Journal of Naturopathy
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• v.11 no.1
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• pp.18-30
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• 2022

Background: It was to develop an air purification system (APS) using an underground air purification layer to verify the effect of basalt forest's underground air (sumgol) on a volcanic Jeju. Finally, it is necessary to analyze these purified air components and their usefulness to the human body in an air experience center. Purpose: It was to collect basalt forest air, analyze its composition, and explore its effect on the human body. Methods: We APS devices installed at four points in the Papaville area of Jeju. The air discharged from the APS was collected and analyzed the recycling components. An installed experience room filled with negative ions is about 5,000 ions/m³. After allowing the participants to stay for 60 to 120 minutes, we investigated the state of blood vessels. Results: In the analysis of the underground air, the O₂ concentration was 21.18%, which was higher than the average oxygen concentration of 20.94% in the atmosphere. However, Formaldehyde was not detected, and the CO₂ was 419 ppm, which was lower than that of indoor air. The PM2.5 concentration was less than 24 ㎍/m³ and detected anions over 5.000 /m³. The experiencer's vascular states improved, and the increase in pulse rate and stress relief were high. Conclusions: The valuable ingredients identified by analyzing the air were precious for natural healing. The experience results showed that it effectively improved the pulse rate, blood vessels, and stress. These conditions may be highly beneficial as a new area for expanding the basalt lava forest in the Jeju area into the natural healing and wellness industry.

• Journal of Bio-Environment Control
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• v.31 no.4
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• pp.444-451
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• 2022

Recently, long-term cultivation is becoming more common with the increase in tomato hydroponics. In hydroponics, it is very important to supply an appropriate nutrient solution considering the nutrient and moisture requirements of crops, in terms of productivity, resource use, and environmental conservation. Since seasonal environmental changes appear severely in long-term cultivation, it is so critical to manage irrigation control considering these changes. Therefore, this study was carried out to investigate the effect of irrigation volume on growth and yield in tomato long-term cultivation using coir substrate. The irrigation volume was adjusted at 4 levels (high, medium high, medium low and low) by different irrigation frequency. Irrigation scheduling (frequency) was controlled based on solar radiation which measured by radiation sensor installed outside the greenhouse and performed whenever accumulated solar radiation energy reached set value. Set value of integrated solar radiation was changed by the growing season. The results revealed that the higher irrigation volume caused the higher drainage rate, which could prevent the EC of drainage from rising excessively. As the cultivation period elapsed, the EC of the drainage increased. And the lower irrigation volume supplied, the more the increase in EC of the drainage. Plant length was shorter in the low irrigation volume treatment compared to the other treatments. But irrigation volume did not affect the number of nodes and fruit clusters. The number of fruit settings was not significantly affected by the irrigation volume in general, but high irrigation volume significantly decreased fruit setting and yield of the 12-15th cluster developed during low temperature period. Blossom-end rot occurred early with a high incidence rate in the low irrigation volume treatment group. The highest weight fruits was obtained from the high irrigation treatment group, while the medium high treatment group had the highest total yield. As a result of the experiment, it could be confirmed the effect of irrigation amount on the nutrient and moisture stabilization in the root zone and yield, in addition to the importance of proper irrigation control when cultivating tomato plants hydroponically using coir substrate. Therefore, it is necessary to continue the research on this topic, as it is judged that the precise irrigation control algorithm based on root zone-information applied to the integrated environmental control system, will contribute to the improvement of crop productivity as well as the development of hydroponics control techniques.

• Journal of Appropriate Technology
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• v.6 no.2
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• pp.174-182
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• 2020

The permissible limit of ammonia concentration in drinking water recommended by the World Health Organization (WHO) is 1.5 mg/L. However, in the case of groundwater in Kathmandu, Nepal, the concentration of ammonia fluctuates dramatically from 0 to 120 mg/L at different locations and groundwater depths (Chapagain et al., 2010). Such a high concentration of ammonia causes aesthetic problems in drinking water, such as bad taste and odor; hence, prior treatment is required. In Kathmandu, half of the population utilizes groundwater, which is also employed for drinking water, but owing to a lack of knowledge of household water filters, residents of Kathmandu tend to depend greatly on commercially available jar water than on the installation of a proper household filtration method. Thus, in our study, we employed adsorption and reverse osmosis (RO) as two of the most viable decentralized/household treatment options to address the issue of high contamination of ammonia in drinking water. We evaluated their performances from technical and the economic perspectives using synthetically prepared groundwater at varying ammonia concentrations (50 mg/L and 15 mg/L). Consequently, it was found that adsorption via ion exchange (IE) resin was a comparatively better ammonia removal technology than RO, with 100% ammonia removal even after regeneration; the removal by RO was limited to up to 90%. Furthermore, our study suggests that IE is the most suitable ammonia removal technology for places with lower water consumption (< 50 L/day), whereas RO seemed to be a cost-effective technology for places with higher water consumption, where the daily water demand exceeds 50 L/day. Lastly, these assessments suggest that installing a suitable household treatment system would be more efficient and sustainable from both technical and economic points of view than purchasing commercially bottled water.

• Economic and Environmental Geology
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• v.55 no.1
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• pp.63-76
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• 2022

Dacitic tuffs, 97 to 118 m thick, were recovered from the lower part of the subsurface Seongdongri Formation, Janggi Basin, which was drilled to assess the potential for underground storage of carbon dioxide. The tuffs are divided into four depositional units(Unit 1 to 4) based on internal structures and particle componentry. Unit 1 and Units 3/4 are ignimbrites that accumulated in subaerial and subaqueous settings, respectively, whereas Unit 2 is braided-stream deposits that accumulated during a volcanic quiescence, and no dacitic tuff is observed. A series of analysis shows that mordenite and clinoptilolite mainly fill the vesicles of glass shards, suggesting their formation by replacement and dissolution of volcanic glass and precipitation from interstitial water during burial and diagenesis. Glass-replaced clinoptilolite has higher Si/Al ratios and Na contents than the vesicle-filling clinoptilolite in Units 3. However, the composition of clinoptilolite becomes identical in Unit 4, irrespective of the occurrence and location. This suggests that the Si/Al ratio and pH in the interstitial water increased with time because of the replacement and leaching of volcanic glass, and that the composition of interstitial water was different between the eastern and western parts of the basin during the formation of the clinoptilolite in Units 1 and 3. It is also inferred that the formation of the two zeolite minerals was sequential according to the depositional units, i.e., the clinoptilolite formed after the growth of mordenite. To summarize, during a volcanic quiescence after the deposition of Unit 1, pH was higher in the western part of the basin because of eastward tilting of the basin floor, and the zeolite ceased to grow because of the closure of the pore space as a result of the growth of smectite. On the other hand, clinoptilolite could grow in the eastern part of the basin in an open system affected by groundwater, where braided stream was developed. Afterwards, Units 3 and 4 were submerged under water because of the basin subsidence, and the alkali content of the interstitial water increased gradually, eventually becoming identical in the eastern and western parts of the basin. This study thus shows that volcanic deposits of similar composition can have variable distribution of zeolite mineral depending on the drainage and depositional environment of basins.

• Journal of Intelligence and Information Systems
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• v.29 no.1
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• pp.1-25
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• 2023

ESG management is becoming a necessity of the times, but there are about 600 ESG evaluation indicators worldwide, causing confusion in the market as different ESG ratings were assigned to individual companies according to evaluation agencies. In addition, since the method of applying ESG was not disclosed, there were not many ways for companies that wanted to introduce ESG management to get help. Accordingly, the Ministry of Trade, Industry and Energy announced the K-ESG guideline jointly with the ministries. In previous studies, there were few studies on the comparison of evaluation grades by ESG evaluation company or the application of evaluation diagnostic items. Therefore, in this study, the ease of application and improvement of the K-ESG guideline was attempted by applying the K-ESG guideline to companies that already have ESG ratings. The position of the K-ESG guideline is also confirmed by comparing the scores calculated through the K-ESG guideline for companies that have ESG ratings from global ESG evaluation agencies and domestic ESG evaluation agencies. As a result of the analysis, first, the K-ESG guideline provide clear and detailed standards for individual companies to set their own ESG goals and set the direction of ESG practice. Second, the K-ESG guideline is suitable for domestic and global ESG evaluation standards as it has 61 diagnostic items and 12 additional diagnostic items covering the evaluation indicators of global representative ESG evaluation agencies and KCGS in Korea. Third, the ESG rating of the K-ESG guideline was higher than that of a global ESG rating company and lower than or similar to that of a domestic ESG rating company. Fourth, the ease of application of the K-ESG guideline is judged to be high. Fifth, the point to be improved in the K-ESG guideline is that the government needs to compile industry average statistics on diagnostic items in the K-ESG environment area and publish them on the government's ESG-only site. In addition, the applied weights of E, S, and G by industry should be determined and disclosed. This study will help ESG evaluation agencies, corporate management, and ESG managers interested in ESG management in establishing ESG management strategies and contributing to providing improvements to be referenced when revising the K-ESG guideline in the future.

• The Korean Journal of Nuclear Medicine Technology
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• v.26 no.2
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• pp.15-19
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• 2022

Purpose [⁶⁸Ga]PSMA-11 is needed the high reproducibility, excellent radiochemical yield and purity. In term of radiation safety, the radiation exposure of operator for its production also should be considered. In this work, we performed a comparative study for the fully automated synthesis of [⁶⁸Ga]PSMA-11 between non-cassette type and cassette type. Materials and Methods Two different type of modules (TRACERlab FX N pro for non-cassette type and BIKBox for cassette type) were used for the automated production of [⁶⁸Ga]PSMA-11. According to the previously identified elution profile, Only 2.5 ml with high radioactivity was used for the reaction. After adjusting the pH of the reaction solution with HEPES buffer solution, the precursor was added and reacted with at 95 ℃ for 15 minutes. The reaction mixture was separated and purified using a C18 light cartridge. The product was eluted with 50% EtOH/saline solution and diluted with saline. It was completed by sterilizing filter. In the non-cassette type, the aforementioned process must be prepared directly. However, in the cassette method, synthesis was possible simply by installing a kit that was already completed. Results Both total [⁶⁸Ga]PSMA-11 production time were 25±3(non-cassette type) and 23±3 minutes(cassette type). The radiochemical yield of the non-cassette type(65.5±5.7%) was higher than that of the cassette type(61.6±4.8%) after sterilization filter. The non-cassette type took about 120 minutes of preparation time before synthesis due to washing of synthesizer and reagent preparation. However, since the cassette type does not require washing and reagent preparation, it took about 20 minutes to prepare before synthesis. Both type of synthesizer had a radiochemical high purity(>99%). Conclusion The non-cassette type production of [⁶⁸Ga]PSMA-11 showed higher radiochemical yield and lower cost than the cassette type. However, The cassette type has an advantage in terms of preparation time, convenience, and equipment maintenance.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.9 no.1
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• pp.9-16
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• 2023

Liposomes as drug delivery system have proved useful carrier for various disease, including cancer. In addition, perfluorocarbon cored microbubbles are utilized in conjunction with high-intensity focused-ultrasound (HIFU) to enable simultaneous diagnosis and treatment. However, microbubbles generally exhibit lower drug loading efficiency, so the need for the development of a novel liposome-based drug delivery material that can efficiently load and deliver drugs to targeted areas via HIFU. This study aims to develop a liposome-based drug delivery material by introducing a substance that can burst liposomes using ultrasound energy and confirm the ability to target tumors using PET imaging. Liposomes (Lipo-DOX, Lipo-DOX-Au, Lipo-DOX-Au-RGD) were synthesized with gold nanoparticles using an avidin-biotin bond, and doxorubicin was mounted inside by pH gradient method. The size distribution was measured by DLS, and encapsulation efficiency of doxorubicin was analyzed by UV-vis spectrometer. The target specificity and cytotoxicity of liposomes were assessed in vitro by glioblastoma U87mg cells to HIFU treatment and analyzed using CCK-8 assay, and fluorescence microscopy at 6-hour intervals for up to 24 hours. For the in vivo study, U87mg model mouse were injected intravenously with 1.48 MBq of ⁶⁴Cu-labeled Lipo-DOX-Au and Lipo-DOX-Au-RGD, and PET images were taken at 0, 2, 4, 8, and 24 hours. As a result, the size of liposomes was 108.3 ± 5.0 nm at Lipo-DOX-Au and 94.1 ± 12.2 nm at Lipo-DOX-Au-RGD, and it was observed that doxorubicin was mounted inside the liposome up to 52%. After 6 hours of HIFU treatment, the viability of U87mg cells treated with Lipo-DOX-Au decreased by around 20% compared to Lipo-DOX, and Lipo-DOX-Au-RGD had a higher uptake rate than Lipo-DOX. In vivo study using PET images, it was confirmed that ⁶⁴Cu-Lipo-DOX-Au-RGD was taken up into the tumor immediately after injection and maintained for up to 4 hours. In this study, drugs released from liposomes-gold nanoparticles via ultrasound and RGD targeting were confirmed by non-invasive imaging. In cell-level experiments, HIFU treatment of gold nanoparticle-coupled liposomes significantly decreased tumor survival, while RGD-liposomes exhibited high tumor targeting and rapid release in vivo imaging. It is expected that the combination of these models with ultrasound is served as an effective drug delivery material with therapeutic outcomes.

• Korean Journal of Environment and Ecology
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• v.36 no.6
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• pp.592-602
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• 2022

This study aimed to check habitat distribution and analyze influencing factors by analyzing the mating calls of Auritibicen intermedius inhabiting limited locations in South Korea by applying bioacoustic detection techniques. The study sites were 20 protection areas nationwide. The mating call analysis period was 4 years from 2017 to 2021, excluding 2020. The bioacoustic recording system installed at each study site collected recordings of mating calls every day for 1 minute per hour. Climate data received from the Meteorological Agency, such as temperature, humidity, rainfall, cloudiness, and sunshine, were analyzed. The results of this study identified A. intermedius habitat only in four national parks in the highlands of Gangwon Province (Mt. Seorak, Mt. Odae, Mt. Chiak, and Mt. Taebak) out of 20 study sites. During the four years of study, the mating call period of A. intermedius was between August 5 and September 28, and the duration of the mating call was 31 to 52 days. The temperature analysis during the appearance period of A. intermedius showed that A. intermedius mainly produced mating calls at temperatures between 13.1℃ and 35.3℃, and the average temperature during the circadian cycle of mating calls (09:00 to 16:00) was 24.4 to 24.9℃. The analysis of the circadian cycle of mating calls at four study sites where A. intermedius appeared in 2019 showed that A. intermedius produced mating calls from 06:00 to 16:00 and that they peaked around 11:00 to 12:00. During the appearance period of A. intermedius, four species appeared in common: Hyalessa maculaticollis, Meimuna opalifera, Graptopsaltria nigrofuscata, and Suisha coreana. A logistic regression analysis confirmed that sunlight was the environmental factor affecting the mating call of A. intermedius. Regarding interspecific influence, it was confirmed that A. intermedius exchanged interspecific influence with 4 other common species (H. maculaticollis, M. opalifera, G. nigrofuscata, and S. coreana). The above results confirmed that A. intermedius habitats were limited in the highlands of Gangwon Province highlands in Korea and produced mating calls at a lower temperature compared to other species. These results can be used as basic data for future research on A. intermedius in Korea.

• Journal of the Korean Geotechnical Society
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• v.26 no.12
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• pp.19-30
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• 2010

Bentonite-based grout has been widely used to seal a borehole constructed for a closed-loop vertical ground heat exchanger in a geothermal heat pump system (GHP) because of its high swelling potential and low hydraulic conductivity. Three types of bentonites were compared one another in terms of viscosity and thermal conductivity in this paper. The viscosity and thermal conductivity of the grouts with bentonite contents of 5%, 10%, 15%, 20% and 25% by weight were examined to take into account a variable water content of bentonite grout depending on field conditions. To evaluate the effect of salinity (i.e., concentration of NaCl : 0.1M, 0.25M, and 0.5M) on swelling potential of the bentonite-based grouts, a series of volume reduction tests were performed. In addition, if the viscosity of bentonite-water mixture is relatively low, particle segregation can occur. To examine the segregation phenomenon, the degree of segregation has been evaluated for the bentonite grouts especially in case of relatively low viscosity. From the experimental results, it is found that (1) the viscosity of the bentonite mixture increased with time and/or with increasing the mixing ratio. However, the thermal conductivity of the bentonite mixture did not increase with time but increased with increasing the mixing ratio; (2) If bentonite grout has a relatively high swelling index, the volume reduction ratio in the saline condition will be low; (3) The additive, such as a silica sand, can settle down on the bottom of the borehole if the bentonite has a very low viscosity. Consequently, the thermal conductivity of the upper portion of the ground heat exchanger will be much smaller than that of the lower portion.

• Journal of Intelligence and Information Systems
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• v.28 no.1
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• pp.263-286
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• 2022

This study acquires NBA statistical information for a total of 32 years from 1990 to 2022 using web crawling, observes variables of interest through exploratory data analysis, and generates related derived variables. Unused variables were removed through a purification process on the input data, and correlation analysis, t-test, and ANOVA were performed on the remaining variables. For the variable of interest, the difference in the mean between the groups that advanced to the playoffs and did not advance to the playoffs was tested, and then to compensate for this, the average difference between the three groups (higher/middle/lower) based on ranking was reconfirmed. Of the input data, only this year's season data was used as a test set, and 5-fold cross-validation was performed by dividing the training set and the validation set for model training. The overfitting problem was solved by comparing the cross-validation result and the final analysis result using the test set to confirm that there was no difference in the performance matrix. Because the quality level of the raw data is high and the statistical assumptions are satisfied, most of the models showed good results despite the small data set. This study not only predicts NBA game results or classifies whether or not to advance to the playoffs using machine learning, but also examines whether the variables of interest are included in the major variables with high importance by understanding the importance of input attribute. Through the visualization of SHAP value, it was possible to overcome the limitation that could not be interpreted only with the result of feature importance, and to compensate for the lack of consistency in the importance calculation in the process of entering/removing variables. It was found that a number of variables related to three points and errors classified as subjects of interest in this study were included in the major variables affecting advancing to the playoffs in the NBA. Although this study is similar in that it includes topics such as match results, playoffs, and championship predictions, which have been dealt with in the existing sports data analysis field, and comparatively analyzed several machine learning models for analysis, there is a difference in that the interest features are set in advance and statistically verified, so that it is compared with the machine learning analysis result. Also, it was differentiated from existing studies by presenting explanatory visualization results using SHAP, one of the XAI models.