• Biomolecules & Therapeutics
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• 제8권2호
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• pp.119-124
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• 2000

We hypothesized that the extent of hypoxic injury would be involved in reduction of oxygen delivery to the tissue. Livers isolated from 18 hr-fasted rats were subjected to $N_2$-induced hypoxia or low flow hypoxia. Livers were perfused with nitrogen/carbon dioxide gas for 45min or perfused with normoxic Krebs-Henseleit bicarbonate buffer (KHBB) at low flow rates around 1 ml/g liver/min far 45min, which caused cells to become hypoxic because of insufficient delivery of oxygen. When normal flow rates(4 ml/g liver/min) of KHBB (pH 7.4, 37$^{\circ}C$, oxygen/carbon dioxide gas) were restored for 30min reoxygenation injury occurred. Lactate dehydrogenase release gradually increased in $N_2$-induced hypoxia, whereas it rapidly increased in low flow hypoxia. Total glutathione in liver tissue was not changed but oxidized glutathione markedly increased after hypoxia and reoxygenation, expecially in $N_2$-induced hypoxia. Similarly, lipid peroxidation in liver tissue significantly increased after hypoxia and reoxygenation in low flow hypoxia. Hepatic drug metabolizing functions (phase I, II) were suppressed during hypoxia, especially in $N_2$-induced hypoxia but improved by reoxygenation in both models. Our findings suggest that hypoxia results in abnormalities in drug metabolizing function caused by oxidative stress and that this injury is dependent on hypoxic conditions.

• 한국전산유체공학회지
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• 제15권2호
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• pp.55-61
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• 2010

A dependence of weighting parameter in preconditioning method for solving low Mach number flow with incompressible flow nature is investigated. The present preconditioning method employs a finite-difference method applied Roe‘s flux difference splitting approximation with the MUSCL-TVD scheme and 4th-order Runge-Kutta method in curvilinear coordinates. From the computational results of benchmark flows through a 2-D backward-facing step duct it is confirmed that there exists a suitable value of the weighting parameter for accurate and stable computation. A useful method to determine the weighting parameter is introduced. With this method, high accuracy and stable computational results were obtained for the flow with low Mach number in the range of Mach number less than 0.3.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2009년 추계학술대회논문집
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• pp.159-163
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• 2009

In this paper, the fluid dynamic forces and performances of a moving airfoil in the low Reynolds number flow is addressed. In order to calculate the necessary propulsive force for the moving airfoil in a low Reynolds number flow, a lattice-Boltzmann method is used. The critical Reynolds and Strouhal numbers for the thrust generation are investigated for the four propulsion types. It was found that the Normal P&D type produces the largest thrust with highest efficiency among the investigated types. The leading edge of the airfoil has an effect of deciding the force production types, whereas the trailing edge of the airfoil plays an important role in augmenting or reducing the instability produced by the leading edge oscillation. It is believed that present results can be used to decide the optimal propulsion devices for the given Reynolds number flow.

• 한국연소학회:학술대회논문집
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• 한국연소학회 2001년도 제23회 KOSCO SYMPOSIUM 논문집
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• pp.17-26
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• 2001

Self flue gas recirculation flow is an effective method for low NOx emission in the regenerative low NOx burner. The object of this study is to analyze the self flue gas recirculating flow by varying jet velocity of the combustion air. Fuel and air flow rates are fixed and combustion air jet nozzle diameters are 13, 6.5 and 5mm. The stoichiometric line is obtained from the concentration of the fuel using an acetone PLIF technique. It is found that the self flue gas recirculating flow is entrained into that line using a two color PIV technique. As the jet velocity of combustion air is increased, the flue gas entrainment rate into the stoichiometric line is increased. This result suggests that NOx emission can be reduced due to the effects of flue gas which is lowering the flame temperatures.

• 한국원자력학회:학술대회논문집
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• 한국원자력학회 1995년도 추계학술발표회논문집(1)
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• pp.315-320
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• 1995

The CHF phenomenon has been investigated for water flow under forced and natural circulation modes with vertical round tubes at low pressure and low flow condition. Experiments have been performed by using three different test sections for mass fluxes below 400 kg/㎡s under near atmospheric pressure. The experimental data for forced and natural circulation are compared with each other. To predict the flow rate at the two-phase region our test condition has been analyzed by RELAP5/MOD3 because the local two-phase condition inside the stainless steel tube cannot be directly measured. To predict the CHF with accuracy we have to consider the parameters at the single-phase region as well as the flow behavior at the two-phase region.

• 한국연소학회지
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• 제6권1호
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• pp.20-28
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• 2001

Self flue gas recirculation flow is an effective method for low NOx emission in a regenerative low NOx burner. The object of this study is to analyze self flue gas recirculating flow by varying the jet velocity of the combustion air. Fuel and air flow rates are fixed and combustion air jet nozzle diameters are 13, 6.5 and 5mm. The stoichiometric line is obtained from the concentration of fuel using the acetone PLIF technique. It is found that self flue gas recirculating flow is entrained into that line using the two color PIV technique. As the jet velocity of combustion air is increased, the flue gas entrainment rate into the stoichiometric line is increased. This result suggests that NOx emission can be reduced due to the effects of flue gas lowering the flame temperature.

• 한국수자원학회논문집
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• 제32권3호
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• pp.265-279
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• 1999

본 연구에서는, Markov 연쇄 모형에 의해 산정된 모의 일 강우량을 일 유출모형인 Tand 모형에 입력시켜 모의 일유출량을 산정함으로써 저수유량계열을 확장하는 방법을 개발하였다. 또한, 모의된 일 유량계열로부터 지속기간별 연 최저치 계열을 작성하였으며, 지속기간별 연 최저치계열에 대한 빈도분석을 시행하였다. 분석에 사용된 분포형은 Lognormal-2, Lognormal-3, Gamma-2, Gamma-3, LogGamma-3, Gumbel-2, Weibull-2 분포이었으며, 모수추정은 모멘트법과 최우도법을 사용하였다. Kolmogorov - Sminorv 검정방법으로 지속기간별 연 최저치 계열에 적합한 확률분포형을 결정하고, 용담댐 지점을 대상으로 하여 지속기간별 갈수 빈도곡선을 산정하였다. 본 연구에서 제안된 방법을 적용하면 과거 저수 유량계열의 통계적 특성을 잘 나타내는 일 유량의 모의가 가능 하여, 갈수유량계열 자료가 빈곤한 유역에서 확률 갈수량을 추정하는데 유용하리라고 판단된다.

• 소성∙가공
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• 제23권2호
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• pp.116-121
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• 2014

Low pressure die casting and flow forming have been successfully used to produce sound road wheels from magnesium alloy AM80. In the current study, high speed compression testing was initially conducted to simulate the flow forming of a Mg wheel. Subsequently the flow forming was simulated with "Forge$^{TM}$", an FEM software package. On the basis of flow forming simulations, the flow forming of the Mg wheel was performed under different conditions. For the flow forming experiments, the preform castings were made by low pressure die casting from AM80, a commercial magnesium alloy. In flow forming of the magnesium preform wheel, the flow forming of the Mg wheel was successfully accomplished when the feed rate was less than half that for the forming of an aluminum road wheel. The reduction in feed rate was 52%. Finally, a comparison with the flow forming simulations was made.

• Nuclear Engineering and Technology
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• 제37권5호
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• pp.457-468
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• 2005

An experimental study on post-CHF heat transfer has been performed with a $3\times3$ rod bundle using a vertical steam-water two-phase flow at low flow conditions. The effects of various parameters on the post-CHF heat transfer are investigated and the reasons for the parametric effects are discussed. As the heat transfer regime changes from CHF to post-CHF, the radial wall temperature distribution is changed depending on the pressure and the mass flux conditions. The superheat of the fluid increases considerably with an increase of the wall temperature (or heat flux) and with a decrease of the mass flux. This implies, indirectly, a strong thermal non-equilibrium at high wall temperature and low mass flux conditions. In order to improve the prediction accuracy of the existing post-CHF correlations, it is necessary to perform more experiments, particularly direct measurement of the vapor superheat, and to modify the correlation by considering a strong thermal non-equilibrium at low flow and low pressure conditions.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2004년도 춘계 학술대회논문집
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• pp.172-177
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• 2004

In the present work, we have interests on the modification of parallel implemented with MPI(Message Passing Interface) programming method, 3-Dimensional, unsteady, incompressible Navier-Stokes equation solver to analyze the low-Reynolds number flow In order to accurate calculation aerodynamic coefficients in low-Reynolds number flow field, we modified the two-equation turbulence model. This paper describes the development and validation of a new two-equation model for the prediction of flow transition. It is based on Mentor's low Reynolds $\kappa-\omega$ model with modifications to include Total Stresses Limitation (TSL) and Separation Transition Trigger (STT)