• Journal of Acupuncture Research
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• 제38권1호
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• pp.1-7
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• 2021

This review of national and international randomized controlled trials of Salviae miltiorrhizae radix pharmacopuncture for lumbar herniated intervertebral discs was performed to assess its clinical efficacy. There were 5 online databases (PubMed, EMBASE, CNKI, NDSL, OASIS, and RISS) searched on June 1st, 2020. Studies were selected according to the inclusion and exclusion criteria and were reviewed by risk of bias assessment. This review included 14 Chinese studies. The sample sizes ranged from 50 to 100. The numbers of treatments ranged from 20 to 30, with most patients receiving 20 treatments. The longest treatment periods were 10-15 and 15-20 days, of which each accounted for 29% of the studies. The most frequently used evaluation indices were the Japanese Orthopedic Association and the Visual Analog Scale scoring method. The most frequently used acupoints were EX18 and BL25, which accounted for 31% of the total number of acupoints. In 50% of the studies, the pharmacopuncture injection volume was 2 mL. Acupuncture treatment was the most common control group. Eleven studies reported that the intervention group had significantly improved symptoms. However, most of the included studies were of low quality.

• Imaging Science in Dentistry
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• 제51권4호
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• pp.363-372
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• 2021

Purpose: This systematic review and meta-analysis assessed the diagnostic accuracy of imaging examinations for the detection of peri-implant bone defects and compared the diagnostic accuracy between titanium (Ti) and zirconium dioxide (ZrO₂) implants. Materials and Methods: Six online databases were searched, and studies were selected based on eligibility criteria. The studies included in the systematic review underwent bias and applicability assessment using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool and a random-effect meta-analysis. Summary receiver operating characteristic (sROC) curves were constructed to compare the effect of methodological differences in relation to the variables of each group. Results: The search strategy yielded 719 articles. Titles and abstracts were read and 61 studies were selected for full-text reading. Among them, 24 studies were included in this systematic review. Most included studies had a low risk of bias (QUADAS-2). Cone-beam computed tomography (CBCT) presented sufficient data for quantitative analysis in ZrO₂ and Ti implants. The meta-analysis revealed high levels of inconsistency in the latter group. Regarding sROC curves, the area under the curve (AUC) was larger for the overall Ti group (AUC=0.79) than for the overall ZrO₂ group (AUC=0.69), but without a statistically significant difference between them. In Ti implants, the AUCs for dehiscence defects(0.73) and fenestration defects(0.87) showed a statistically significant difference. Conclusion: The diagnostic accuracy of CBCT imaging in the assessment of peri-implant bone defects was similar between Ti and ZrO₂ implants, and fenestration was more accurately diagnosed than dehiscence in Ti implants.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제33권1호
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• pp.2-15
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• 2022

Objectives: Children with attention-deficit/hyperactivity disorder (ADHD) tend to be noisy and violate rules with their disruptive behaviors, resulting in greater difficulties with off-task behaviors and being at risk for social refusal. The visual activity schedule (VAS) intervention program is a frequently used method to teach multiple skills involving on-task, use of schedules, transition behaviors, social initiation, independent play skills, classroom skills, and academic skills. The current systematic review aimed to examine the efficacy of using VAS intervention in reducing problem behaviors in children with ADHD between 5 and 12 years of age. Methods: Systematic searches were conducted using two electronic databases (PubMed and Scopus) to identify relevant studies published in English between 2010 and 2020. Four studies met the inclusion criteria: two studies examined the effect of schedule-based tasks and the use of an iPad on classroom skills, while the other two examined randomized clinical trials (RCTs) of psychosocial treatment for ADHD inattentive type and a cross-sectional study examined the impact of the group size on task behavior and work productivity in children with ADHD. Results: The findings indicate that the interventions used in all four studies could lead to increased satisfaction among participants and parents, as well as a reduction in problem behavior. In terms of the research indicators, the RCT had low quality, while the others were of high quality. Conclusion: A larger number of studies and the ADHD clinical population would help to increase the generalizability of future reviews of treatments in this context.

• 대한한방부인과학회지
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• 제36권3호
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• pp.154-172
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• 2023

Objectives: This study aimed to assess the clinical evidence supporting the use of acupuncture (AC) for premenstrual syndrome (PMS). Methods: We searched randomized controlled trials (RCTs) that used AC for PMS in 9 databases (PubMed, EMBASE, Cochrane Library, CINAHL, CNKI, CiNii, SCIENCE ON, KoreaMed, OASIS) from their inception to July 2022. Results: We identified 1,168 studies, of which 15 RCTs met the inclusion criteria. The risk of bias in the included studies was relatively unclear or high. Meta-analysis of 3 RCTs showed that the AC group had a significantly higher effective rate than the Medroxyprogesterone group (RR 1.48, 95% CI (1.23, 1.78), p<0.0001). Meta-analysis of 2 RCTs showed that there was no statistically significant difference between the AC group and the Sham AC group in the effective rate (RR 4.72, 95% CI (0.88, 25.36), p=0.07). In a review of individual studies, the AC group was more effective than the control group in terms of the effective rate, symptom scale, quality of life, adverse events, and recurrence rate. Conclusions: The AC group was more effective than general treatments groups such as sham AC, western medicine, and dietary supplements, and there were no serious adverse events. However, the evidence on the effectiveness and safety of acupuncture for PMS was inconclusive due to the small number of included studies and low quality. Therefore, systematic reviews based on more rigorously designed randomized clinical trials are needed in the future to properly evaluate the effect of AC on PMS.

• 여성건강간호학회지
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• 제29권1호
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• pp.12-19
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• 2023

Purpose: The aim of this study was to conduct a scoping review of knowledge and information delivery modes related to preconception care (PCC) among adolescent girls and women. Methods: A scoping review was performed on studies selected from five electronic databases (Cochrane Library, PubMed, Science Direct, CINAHL/EBSCO, and ProQuest), published between 2012 and 2022, with predetermined keywords and criteria. We included English-language research articles available in full text and excluded irrelevant articles. Results: This study included eight articles, comprising seven quantitative studies and one qualitative study conducted among adolescent girls and women. Five were from low- and middle-income countries and three were from high-income countries. The synthesized themes generated from the data were PCC knowledge and PCC information delivery modes and effectiveness. In general, adolescent girls and women were found to have basic PCC knowledge, including risk prevention and management and a healthy lifestyle, although more extensive knowledge was found in higher-income countries than in lower-income countries. The delivery modes of PCC information have grown from individual face-to-face conventional methods, which are used predominantly in lower-income countries, to more effective digital mass media. Conclusion: Globally, many women still have insufficient knowledge regarding PCC, as not all of them receive access to PCC information and support. PCC promotion efforts should be initiated earlier by involving a wider group of reproductive-age women and combining individual, in-group, face-to-face, and electronic delivery modes.

• Restorative Dentistry and Endodontics
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• 제47권3호
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• pp.34.1-34.12
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• 2022

Objectives: This study aimed to evaluate the success rate of endodontic treatments performed by undergraduate students and the factors associated with the outcome. Materials and Methods: A follow-up of 3 to 8 years after root canal filling was carried out in 91 patients. At the follow-up visits, medical and dental history questionnaires were applied along with clinical and radiographic examinations. Data collected in the clinical exam included: the presence of pain, swelling, sinus tract, mobility, tenderness to palpation and percussion, periodontal probing profile, and type/quality of coronal restoration. Postoperative and follow-up radiographs were digitalized and analyzed by 2 trained and calibrated examiners to assess periapical healing. The treatment outcome was based on strict clinical and radiographic criteria and classified as success (absence of any clinical and radiographic sign of apical periodontitis) or failure (other combination). Logistic regression was used to investigate the impact of clinical and radiographic variables on endodontic treatment outcomes at a 5% significance level. Results: The success rate of endodontic treatments was 60.7%. The only risk factor significantly associated with failure was the presence of a periapical lesion on the postoperative radiograph (odds ratio, 3.35; 95% confidence interval, 1.17-9.54). Conclusions: The success rate of endodontic treatments performed by undergraduate students was low and was jeopardized by the presence of a periapical lesion on the postoperative radiograph.

• Journal of Preventive Medicine and Public Health
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• 제56권6호
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• pp.542-551
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• 2023

Objectives: Prospective studies on vaccination status and mortality related to coronavirus disease 2019 (COVID-19) in low-resource settings are still limited. We assessed the association between vaccination status (full, partial, or none) and in-hospital mortality among COVID-19 patients at most hospitals in Jakarta, Indonesia during the Delta predomination wave. Methods: We conducted a retrospective cohort study among hospitalized COVID-19 patients who met the study criteria (>18 years old and admitted for inpatient treatment because of laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection). We linked individual-level data in the hospital admission database with vaccination records. Several socio-demographic and clinical characteristics were also analyzed. A Cox proportional hazards regression model was used to explore the association between vaccination status and in-hospital mortality in this patient group. Results: In total, 40 827 patients were included in this study. Of these, 70% were unvaccinated (n=28 543) and 19.3% (n=7882) died during hospitalization. The mean age of the patients was 49 years (range, 35-59), 53.2% were female, 22.0% had hypertension, and 14.2% were treated in the intensive care unit, and the median hospital length of stay across the group was 9 days. Our study showed that the risk of in-hospital mortality among fully and partially vaccinated patients was lower than among unvaccinated adults (adjusted hazard ratio [aHR], 0.43; 95% confidence interval [CI], 0.40 to 0.47 and aHR, 0.70; 95% CI, 0.64 to 0.77, respectively). Conclusions: Vaccinated patients had fewer severe outcomes among hospitalized adults during the Delta wave in Jakarta. These features should be carefully considered by healthcare professionals in treating adults within this patient group.

• Korean Chemical Engineering Research
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• 제61권1호
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• pp.80-88
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• 2023

저밀도 폴리에틸렌(Low-density polyethylene, LDPE)은 분진폭발 관련 특성치에 대한 기준이 제시되고 있지 않아 제조 및 취급설비의 안전한 설계가 어렵다. 이 연구에서는 LDPE 제조공정 중 Bag Filter에서 채취한 분진(LDPE 1)과 Silo 등의 설비 외부에 누설된 퇴적 분진(LDPE 2)에서 채취한 2개 시료에 대하여 분진폭발 시험을 수행하였고 그 중 LDPE 2 분진에 대하여 요약하였다. 입도분석 결과, 체적기준 평균입경은 95.04 ㎛, 수밀도는 0~1 ㎛로 나타났다. 최대폭발압력(P_max)은 6.6 bar, 최대폭발압력상승속도는 1500 g/m³에서 366 [bar/s]로 분진폭발지수(K_st)는 99.4 bar·m/s로 ST-1 등급임을 확인하였다. 또한, 최소점화에너지는 10 mJ이며 최소점화온도는 450 ℃로 나타났다. 현재, 제조 및 취급 설계는 고밀도 폴리에틸렌(HDPE)의 특성값을 기초로 한다. 그러나, 시험 결과 LDPE 2 분진이 HDPE(입자지름 61.6 ㎛)보다 위험성이 높은 것으로 나타나 LDPE 제조공정에서 HDPE 설계기준을 적용할 때는 주의가 필요하다.

• 한국국방경영분석학회지
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• 제36권1호
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• pp.77-90
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• 2010

상용품목을 군용환경에서 적용하면 저비용, 빠른 조달시간, 기술적 발전 등 여러 가지 이점이 있다. 반면에 상용 제품, 표준, 관행 등이 군용 요구조건에 미달됨으로 인하여 신뢰도 및 병참 상의 문제가 발생할 수도 있다. 또한 상용 공급자들은 군용 병참을 지원하는데 필요한 기술적 자료를 제공한 경험이 거의 없을 수도 있다. 보다 많은 회사들이 제품 관련 데이터 수집 시스템을 구축하고 있어 상당한 분량의 사용현장 보증 데이터가 수집되었다. 사용현장 데이터는 전형적으로 주기별 판매량과 클레임 건수로 구성된다. 본 연구에서는 군용환경에서 작동하는 군용설비, 군용환경에서 작동하는 상용설비, 상용환경에서 작동하는 상용설비 등 세 가지 유형의 데이터를 고려하였다. 최대우도 기준 및 최소제곱 기준에 기초한 제품 신뢰도 추정 방법을 제안하고, 각 유형의 데이터에 대한 추정 모형을 구축하고 상용환경에서 군용환경으로 전환하는 신뢰도 변환방법을 제안하였다. 사례연구를 통하여 제안된 방법의 적용 가능성을 검증하였다.

• 대한임상검사과학회지
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• 제50권2호
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• pp.136-143
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• 2018

심근부담률은 심근산소소비량을 간접적으로 측정하는 지표로 심박수와 수축기 혈압의 곱으로 나타내며, 심근이 받는 부담을 나타낸다. 본 연구는 한국성인을 대상으로 트레드밀 운동부하 검사시 대사증후군에 따른 심근부담률의 적정 수준을 제시함으로써 대사증후군 유병률을 낮추기 위한 심근부담률의 목표치를 설정하여 그 기준을 제시하고자 하였다. 대사증후군 진단은 National Cholesterol Education Program (NCEP)의 Adult Treatment Panel (ATP) III에서 제시한 5가지 진단기준 중 3개 이상 충족하는 경우 대사증후군 진단군(MetS, N=25), 1~2개의 기준에 해당하는 경우를 대사증후군 전단계군(Pre-MetS, N=106), 5개의 진단기준에 해당하지 않는 경우는 대사증후군 위험요인이 없는군(Non-MetS, N=65)으로 분류하였다. 운동부하검사는 Bruce 프로토콜에 따라 시행하였다. 심근부담률은(심박수${\times}$수축기 혈압)${\div}1,000$으로 구하였다. 본 연구결과 대사증후군 진단군에서 도달한 일량이 낮음에도 불구하고 최대 수축기 혈압이 높은 것으로 나타났다. 또한 대사증후군에 따른 운동부하 검사시 심근부담률의 최적 임계점은 운동부하검사 1단계에서는 $12.56mmHg{\times}beats/min{\times}10^{-3}$, 운동부하검사 2단계는 $16.94mmHg{\times}beats/min{\times}10^{-3}$, 운동부하검사 3단계에서는 $21.11mmHg{\times}beats/min{\times}10^{-3}$로 나타났다.