• 대한의용생체공학회:의공학회지
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• 제36권5호
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• pp.162-168
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• 2015

In this study, we suggested the performance and safety testing guideline for low intensity pulsed ultrasound (LIPUS) represented by the ultrasound fracture treatment device and cartilage treatment device and low intensity focused ultrasound (LIFU) represented by ultrasonic face lifting device. For these study, the international standards and management regulations of Korea, Japan and United State were analyzed. And the usefulness and applicability were evaluated by testing with commercial equipment and reflecting the views of the industry and experts. As a result of this study, the safety and performance test guidelines for low intensity therapeutic ultrasound device were proposed by presenting the 10 items for LIPUS and 12 items for LIFU. The suggested guidelines are considered a high utilization in the domestic testing and approval authorities. And they are also thought to be useful to new technology development.

• The Journal of Korean Physical Therapy
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• 제25권3호
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• pp.136-142
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• 2013

Purpose: The application of transcutaneous electrical nerve stimulation (TENS) is beneficial for joint movements, inhibition of spasticity, and the improvement of walking ability in patients with chronic hemiplegia. This study aimed to identify the effect of the application of TENS to the knee extensor on the affected side with respect to postural-sway distance and velocity during the sit-to stand movement. Methods: We included 19 patients with post-stroke hemiplegia in this study. They underwent measurements during the sit-to stand movement on a force plate with 5 different stimulation dosages applied over 7 s:No TENS, high-frequency and high intensity TENS, high-frequency and low intensity TENS, low-frequency and high intensity TENS, and low-frequency and low intensity TENS The 5 different condition were administered in random order. Results: The group that received TENS application exhibited a significant decrease in path length and average velocity of center of pressure (COP) displacement compared with the group that did not receive TENS application. TENS dosage at low frequency (3Hz) and high intensity yielded a significant decrease in path length, average velocity, mediolateral distance and anteroposterior distance of COP displacement (p<0.05). Conclusion: Our results demonstrated the effectiveness of the application of low-frequency TENS on STS performance. These findings provide useful information on the application of TENS for the reduction of postural sway during the sit-to-stand movement after stroke.

• 한국전문물리치료학회지
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• 제4권2호
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• pp.36-50
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• 1997

The purpose of this study was to compare the effects of high intensity, high frequency microcurrent electrical neuromuscular stimulation(MENS) of auricular and somatic acupuncture points and low intensity, low frequency microcurrent electrical neuromuscular stimulation(MENS) of auricular and somatic acupuncture points on experimental pressure threshold at the elbow according to the time. Fifty healthy adults, aged 19 to 26 years, were assigned randomly to one of five groups: 1) the high intensity, high frequency somatic group(n=10) received MENS to somatic acupuncture points, 2) the high intensity, high frequency auricular group(n=10) received MENS to auricular acupuncture points, 3) the low intensity, low frequency somatic group(n=10) received MENS to somatic acupuncture points, 4) the low intensity, low frequency somatic group(n=10) receive MENS to somatic acupuncture points, and 5) the placebo group(n=10) received placebo treatment and served as controls. Pressure threshold was measured before, after, 5 minutes, 10 minutes and 15 minutes. Pressure threshold has increased significantly(p<.05) in the high intensity, high frequency auricular group following treatment after 5 minutes, with no statistically significant differences in pressure threshold change scores among five groups, Only the high intensity, high frequency auricular group demonstrated statistically significant change score in pressure threshold following treatment after, 5 minutes, 10 minutes and 15 minutes after compared to the placebo group. The results indicated that MENS applied to the high intensity, high frequency auricular group increases pressure threshold.

• 한국정밀공학회지
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• 제28권4호
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• pp.521-525
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• 2011

It is known that the low-intensity sound stimulation really affect to grow the cell. The cellular growth mechanism, however, does not been clearly identified even the effect on the low-intensity sound stimulation. The purpose of this study is to investigate the effect of low-intensity sound stimulation on the alveolar UC-MSC proliferation. Before the low-intensity sound stimulation is applied, the UC-MSC are cultured for 24 hours to facilitate their attachments. The cells are divided into two groups. And each was exposed to a medium with or without the low-intensity ultrasound stimulation at 71dB intensity level. The UC-MSC are again divided into three treatment groups of group 1, 2, and 3 and exposed to a frequency at 50Hz, 100Hz, and 1000Hz, respectively. In the results, it is investigated that the growth rates of UC-MSC for the stimulated groups were higher than those of control groups. In 1000Hz frequency, the number of UC-MSC cell is significantly higher than control groups (p>0.05). We would put the hypothesis that the cell growth could be enhanced by an appropriate low-intensity sound stimulation.

• 대한물리의학회지
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• 제10권3호
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• pp.1-7
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• 2015

PURPOSE: The aim of this study was to investigate the effects of exercise intensity and initial timing on functional recovery following sciatic nerve injury in rats. METHODS: Total of 80 Sprague-Dawley rats was used and randomly divided 6 groups. Under deep anesthesia, the sciatic nerve was nipped by adapted hemostatic tweezers for 30 seconds and the injured nerve was transparent under naked eyes. Acute exercise groups was applied treadmill after sciatic nerve crush injury during 5days with three type intensity. Late exercise groups was also applied treadmill during 5 days with three type intensity after 5 days break. Values of sciatic functional index were measured and analyzed in each group after exercise period. RESULTS: The sciatic functional index values between control groups 1, acute low-intensity group, acute middle-intensity group in acute phase showed statistical significant (p<.05). The sciatic functional index values between control groups 2, late low-intensity group, late middle-intensity group and late high-intensity in late phase showed statistical significant (p<.05). The comparison in acute and late phase, sciatic functional index values of each low-intensity group and each high-intensity group showed statistical significant (p<.05). CONCLUSION: Whether at acute or late phase, treadmill exercise as a therapy obtained beneficial effects of functional recovery and exercise training at low speed is more beneficial effects on the recovery of motor function in acute phase.

• 동의생리병리학회지
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• 제21권1호
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• pp.76-81
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• 2007

The effect of either low or high intensity four weeks exercise treadmill running on the activation of the extracellular-signal regulated protein kinase (ERK1/2) and the c-Jun N-terminal kinase(JNK) pathways was determined in rat tibialis muscle. Sprague-Dawley rats were assigned to one of three groups: (i) sedentary group(NE; n=10); (ii) low intensity exercise group (8m/min; LIE; n=10); and (iii) high intensity exercise group(28m/min; HIE; n=10). The training regimens were planned so that animals covered the same distance and had similar glycogenutilization for both LIE and HIE exercise sessions. After four weeks exercise, 48 h after the last exercise bout obtained samples. pERK1 increased 1.5 times comparing with the sedentary group in the low intensity group while it increased 11.7 times in high intensity group, in the tibialis of rats. In the low intensity group, pERK2 increased 1.4 times comparing with the sedentary group while it increased 3.3 times in high intensity group. While pJNK1 decreased 0.9 times, comparing with the sedentary group, pJNK2 was increased to 0.5 times in the low intensity group. But in high intensity group, pJNK2 decreased 0.7 times while pJNK1 didn't show any change. In conclusion, Four weeks exercise of different intensities results in tibialis muscle activation of intracellular signal pathways, which may be one mechanism regulating specific adaptations induced by different exercise intensities.

• 한국임상약학회지
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• 제28권4호
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• pp.293-299
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• 2018

Background: 3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) effectively reduce serum levels of low-density lipoprotein (LDL) and total cholesterol. High-intensity statins are recommended for all patients aged ${\leq}75$ with clinical atherosclerotic cardiovascular disease (ASCVD), diabetes mellitus aged 40-75 with ${\geq}7.5%$ estimated 10-year ASCVD risk and LDL-C ${\geq}190mg/dL$. High-intensity statins associated with more frequent adverse events (AEs) compared to moderate- to low-intensity statins. The aim of this study was to compare AEs between high-intensity and moderate- to low-intensity statin group using the Korea Adverse Event Reporting System (KAERS) database. Methods: Adults (${\geq}18years$) with statin-associated AEs from July 2009-June 2014 were included. Only AEs classified as "certain", "probable" and "possible" based on the WHO-Uppsala Monitoring Center criteria were analyzed. Results: In total, 247 AEs from 196 patients [high-intensity statin group (HG), n = 25 (13%); moderate- to low-intensity statin group (MLG), n = 171 (87%)] were included. Mean age was higher in HG compared with MLG ($67{\pm}14$ vs $62{\pm}12$). The HG showed a significant higher frequency of liver/biliary system disorders (37% vs 14%, p = 0.001). Hepatic function abnormal was reported more frequently in HG compared to MLG (26% vs 9%, p = 0.006). Conclusion: According to KAERS data, liver/biliary system disorders were more frequently reported in HG compared to MLG.

• 대한지역사회작업치료학회지
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• 제4권1호
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• pp.85-92
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• 2014

목적 : 본 연구의 목적은 운동 강도에 따른 지속적인 운동습관이 수면장애 성인에게 어떠한 영향을 줄 수 있는지 알아보고 수면장애에 효과적인 운동 강도를 알아보고자 하였다. 연구방법 : 본 연구는 K시에 거주하는 수면장애를 가진 30, 40대 성인 남성 90명을 대상으로 하였다. 집단은 고강도 운동집단 30명, 중강도 운동집단 30명, 저강도 운동집단 30명으로 구성하였다. 세 집단의 총 수면지수와 멜라토닌 농도의 비교를 통하여 수면장애의 운동 강도별 효과를 비교하였다. 결론 : 수면장애의 운동 강도별 운동을 수행한 결과, 운동 수행 전, 후의 총 수면지수에서 고강도와 중강도의 운동이 유의성이 있었지만 수면장애에서는 중강도 운동이 효과적이었고, 운동수행 전, 후의 멜라토닌 농도 변화에서도 중강도 운동이 효과적이었다. 결론 : 본 연구의 결론은 성인의 수면장애는 지속적인 운동이 효과가 있지만 저강도 운동과 고강도 운동보다는 중강도 운동이 효과적임을 알 수 있었다.

• 한국융합학회논문지
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• 제11권4호
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• pp.343-350
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• 2020

본 연구는 여자 핸드볼 국가대표 선수를 대상으로 관성센서(IMU)를 활용하여 5개월 동안 국내 또는 국외 연습경기 총 16경기를 대상으로 움직임을 정량화하고 훈련의 효율성과 포지션별 움직임 차이를 확인하고자 하였다. 골키퍼를 제외한 15명의 필드플레이어를 대상으로 하였으며 연구결과 다음과 같은 결론을 얻었다. 플레이어로드는 Wing > Back > Pivot 순으로 나타났고 국외경기에서 높은 것으로 나타났다. 좌·우 방향전환은 Pivot이 저강도에서 가장 많은 것으로 나타났고 중·고강도는 Back에서 가장 많이 나타났다. 국외경기의 저·중강도 방향전환 움직임이 많은 것으로 나타났다. 저강도 가속과 감속은 Pivot이 가장 많은 것으로 나타났고 중·고강도 가속과 감속은 Back이 가장 많은 것으로 나타났다. 국외경기에서 저·중강도 가속과 저·중·고강도 감속이 많은 것으로 나타났다. 점프는 Back이 중강도, Wing이 고강도 점프가 많이 나타났지만 경기 유형간 차이는 나타나지 않았다.

• 기본간호학회지
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• 제15권4호
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• pp.457-466
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• 2008

Purpose: The purpose of this study was to determine the effects of low intensity exercise program with telephone coaching on the physical fitness of elderly people who are receiving home visiting nursing care. Method: This study was conducted using a non-equivalent control group pretest-posttest design. The participants were 61 elders. Elders (34) in the experimental group performed low intensity exercise and of these 16 received telephone coaching. The low intensity exercise program consisted of stretching, muscle strengthening with an elastic band, massage, and ball exercise, five days a week, for sixteen weeks. Data were collected from July 2007 to December 2007. $x^2$-test, ANCOVA with SPSS WIN 11.0 program were used to analyse the data. Results: There were statistical differences in the right grasping power in the right hand (p=0.021), Raising behind of right arm (p=0.006), Raising behind of left arm (p=0.007). Conclusion: These results indicate, that a low intensity exercise program with telephone coaching can help improve physical fitness in elders receiving served home visiting nursing care.