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Safety of Aprotinin Under Hypothermic Circulatory Arrest (초저체온 및 순환정지하에서 Aprotinin의 안전성)

  • 장병철;김정택
    • Journal of Chest Surgery
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    • v.30 no.5
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    • pp.501-505
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    • 1997
  • It was reported that use of aprotinin in elderly patients undergoing hypothermic circulatory arrest was associated with an increased risk of renal dysfunction, and myocardial infarction as a result of intravascular coagulation. We reviewed 20 patients who received high-dose aprotinin under deep hypothermic circulatory arrest with(NP group, n= 11) or without selective cerebral perfusion(SP group, n=9). The activated clotting time was exceeded 750 seconds in all but 1 patient. After opening aortic arch, retrograde low flow perfusion was maintained through femoral artery to prevent air embolization to the visceral arteries. Four patients among 20 died during hospitalization'due to bleeding, coronary artery dissection pulmonary hemorrhage and multiple cerebral infarction. Postoperatively, cerebrovascular accidents occurred in two patients; one with preoperative carotid artery dissection and the other with unknown multiple cerebral infarction. In conclusion, use of aprotinin in young patients undergoing hypothermic circulatory arrest did not increase the risk of renal dysfunction or intravascular coagulation if ACT during circulatory arrest is maintained to exceed 750 seconds with low-flow perfusion.

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Enhancing CT Image Quality Using Conditional Generative Adversarial Networks for Applying Post-mortem Computed Tomography in Forensic Pathology: A Phantom Study (사후전산화단층촬영의 법의병리학 분야 활용을 위한 조건부 적대적 생성 신경망을 이용한 CT 영상의 해상도 개선: 팬텀 연구)

  • Yebin Yoon;Jinhaeng Heo;Yeji Kim;Hyejin Jo;Yongsu Yoon
    • Journal of radiological science and technology
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    • v.46 no.4
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    • pp.315-323
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    • 2023
  • Post-mortem computed tomography (PMCT) is commonly employed in the field of forensic pathology. PMCT was mainly performed using a whole-body scan with a wide field of view (FOV), which lead to a decrease in spatial resolution due to the increased pixel size. This study aims to evaluate the potential for developing a super-resolution model based on conditional generative adversarial networks (CGAN) to enhance the image quality of CT. 1761 low-resolution images were obtained using a whole-body scan with a wide FOV of the head phantom, and 341 high-resolution images were obtained using the appropriate FOV for the head phantom. Of the 150 paired images in the total dataset, which were divided into training set (96 paired images) and validation set (54 paired images). Data augmentation was perform to improve the effectiveness of training by implementing rotations and flips. To evaluate the performance of the proposed model, we used the Peak Signal-to-Noise Ratio (PSNR), Structural Similarity Index Measure (SSIM) and Deep Image Structure and Texture Similarity (DISTS). Obtained the PSNR, SSIM, and DISTS values of the entire image and the Medial orbital wall, the zygomatic arch, and the temporal bone, where fractures often occur during head trauma. The proposed method demonstrated improvements in values of PSNR by 13.14%, SSIM by 13.10% and DISTS by 45.45% when compared to low-resolution images. The image quality of the three areas where fractures commonly occur during head trauma has also improved compared to low-resolution images.

A Study of Elementary School Students' Feet Growth by 3D Scan Data (3차원 스캔 데이터에 의한 초등학생의 발 성장에 관한 연구)

  • Lee, Jeong-Eun;Do, Wol-Hee
    • Fashion & Textile Research Journal
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    • v.16 no.6
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    • pp.935-944
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    • 2014
  • This study was about to investigate the characteristics of elementary school students' feet growth, comparing and analyzed the measured values and the index values of 3D scan data. As the results from analyzing the measured values, the all measurement items excluding 'Toe 5 angle' showed some significant differences among the age classes, knowing that the elementary school students' feet were continually grown. Although, the items of length, thickness, width, height and circumference indicate some rapid growth of feet at 11 years old, but it appears slowing growth of 'Foot width' after the age of 11 years old. The angle item didn't show any sequential differences according to ages. As the results from analyzing the index values, the children in higher grades have longer 'Toe 5', thicker ankles, wider and thicker the superior part of feet than the children in lower grades. For the superior and the middle part of feet were lowly raised, their Arch height was low and thick. The inferior part of feet showed narrow width and higher height. Giving that the Medial ball width was wide and the Toe 1 angle is high for the children in higher grades, it is expected that the Metatarsophalangeal I might be more projected than that of children in lower grades. Likewise, knowing that the male students' feet shape was bigger than female students' feet from the result that the male students' index values were higher.

THE EFFECTS OF HEAT TREATMENT ON THE MECHANICAL PROPERTIES OF THE ELGILOY WIRE (열처리가 Elgiloy 선재의 기계적 성질에 미치는 영향)

  • Hur, Tack;Rhee, Byung-Tae;Choi, Seok Kyu;Kim, Hyung-Il
    • The korean journal of orthodontics
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    • v.22 no.3 s.38
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    • pp.557-578
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    • 1992
  • Heat treatment which removes internal stress enhances the mechanical properties of the orthodontic arch wire. The main purpose of this experiment was to investigate the effects of the heat treatment on the mechanical properties of the Elgiloy wire. The Elfiloy wire, 0.016' X 0.022' and 0.018' X 0.025', were heat treated in an electric oven for 5, 10 and 15 minutes at selected temperatures between 300 and $900^{\circ}C$. Tensile strength and load deflection rate were measured to reveal the changes of mechanical property at various conditions, and each specimen was observed under metallurgic microscope. Also to trace the precipitation material due to overheat treatment, a qualitative analysis was carried out with EDS system. It was found that heat treatment at a low temperature caused an increase in the tensile strength and bending resistance, and a maintenance in the fibrous in the tensile strength and bending resistance, and a maintenance in the fibrous structure of both sizes of wire. The changes observed in properties and appearance were probably due to the relief of internal stresses incurred in the metal during cold working. In both sizes of wire the tensile strength and the bending resistance continued to decrease at high temperature, and the fibrous structure continued to disappear then was not observed at $900^{\circ}C$. The carbide precipitation founded in grain boundary at $750^{\circ}C$ probably was other elements carbide (Ni, Co) except Cr. The grain growth was observed at $1100^{\circ}C$. Optimum heat treatment for the 0.016' X 0.022' Elgiloy wire was 10 minutes at $500^{\circ}C$, and for the 0.018' X 0.025' Elgiloy wire it was 5 to 15 minutes at $500^{\circ}C$.

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The relationships between the arrangement of teeth, root resorption, and dental maturity in bovine mandibular incisors

  • An, Jin-kyu;Matsumoto, Yoshiro;Ono, Takashi
    • The korean journal of orthodontics
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    • v.47 no.6
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    • pp.365-374
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    • 2017
  • Objective: The objective of this study is to investigate the eruption pattern and root resorption of the bovine anterior dentition in relation to growth-related parameters based on dental maturity. Methods: A cross-sectional study was conducted on 110 bovine anterior mandibles by using standard radiography, cone-beam computed tomography (CBCT), and actual measurements. We determined the relationships between the stages of dental maturity by using a modification of Demirjian's method and various growth-related parameters, such as the activity of the root-resorbing tissue and mobility of the deciduous teeth. The correlation of growth-related parameters with interdental spacing and distal unusual root resorption (DRR) of the deciduous fourth incisor was assessed. The cause of mesial unusual root resorption (MRR) of the deciduous fourth incisor was determined on the basis of the arrangement of the permanent third incisor. Results: An independent t-test and chi-square test indicated significant differences in growth-related parameters associated with dental arch length discrepancy and factors related to the shedding of deciduous teeth between the low and high dental maturity groups. The samples with interdental spacing and DRR showed a larger sum of mesiodistal permanent crown widths and higher dental maturity than did the respective controls. Samples with MRR tended to show a lingually rotated distal tip of the adjacent tooth crown. Conclusions: Dental maturity has relevance to the interdental spaces and unusual root resorption of mixed dentition. The position of the adjacent tooth crown on CBCT may be correlated with the occurrence of unusual root resorption of the incisor.

Effect of passive self-ligating bracket placement on the posterior teeth on reduction of frictional force in sliding mechanics

  • Kim, Kyu-Ry;Baek, Seung-Hak
    • The korean journal of orthodontics
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    • v.46 no.2
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    • pp.73-80
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    • 2016
  • Objective: The purpose of this study was to investigate the static (SFF) and kinetic frictional forces (KFF) in sliding mechanics of hybrid bracket systems that involve placing a conventional bracket (CB) or active self-ligating bracket (ASLB) on the maxillary anterior teeth (MXAT) and a passive SLB (PSLB) on the maxillary posterior teeth (MXPT). Methods: The samples consisted of two thoroughbred types (group 1, anterior-CB + posterior-CB; group 2, anterior-ASLB + posterior-ASLB) and four hybrid types (group 3, anterior-CB + posterior-PSLB-type 1; group 4, anterior-CB + posterior-PSLB-type 2; group 5, anterior-ASLB + posterior-PSLB-type 1; group 6, anterior-ASLB + posterior-PSLB-type 2) (n = 13 per group). After maxillary dentition alignment and maxillary first premolars removal in the stereolithographically-made typodont system, a $0.019{\times}0.025$-inch stainless steel wire was drawn through the right quadrant of the maxillary arch at 0.5 mm/min for 5 min. The SFF and KFF were measured with a mechanical testing machine and statistical analyses were performed. Results: Four different categories of SFF and KFF were observed among all groups (all p < 0.001). Group 1 demonstrated the highest SFF and KFF; groups 4 and 3 were second and third highest, respectively. The fourth category included groups 2, 5, and 6. Placing PSLBs on the MXPT resulted in significant SFF and KFF reductions in cases with CBs on the MXAT, but not in cases with ASLBs on the MXAT. Conclusions: These data might aid in the development of a hybrid bracket system that enables low-friction sliding of an archwire through the MXPT.

A Study on the Ultrasonic Nondestructive Evaluation of Carbon/Carbon Composite Disks

  • Im, Kwang-Hee;Jeong, Hyun-Jo;Yang, In-Young
    • Journal of Mechanical Science and Technology
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    • v.14 no.3
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    • pp.320-330
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    • 2000
  • It is desirable to perform nondestructive evaluation (NDE) to assess material properties and part homogeneity because the manufacturing of carbon/carbon brake disks requires complicated and costly processes. In this work several ultrasonic techniques were applied to carbon/carbon brake disks (322mm ad, 135mm id) for the evaluation of spatial variations in material properties that are attributable to the manufacturing process. In a large carbon/carbon disk manufactured by chemical vapor infiltration (CYI) method, the spatial variation of ultrasonic velocity was measured and found to be consistent with the densification behavior in CYI process. Low frequency (e.g., 1-5MHz) through-transmission scans based on both amplitude and time-of-flight of the ultrasonic pulse were used for mapping out the material property inhomogeneity. Images based on both the amplitude and the time-of-flight of the transmitted ultrasonic pulse showed significant variation in the radial direction. The radial variations in ultrasonic velocity and attenuation were attributed to a density variation caused by the more efficient densification of pitch impregnation near the id and od and by the less efficient densification away from the exposed edged of the disk. Ultrasonic velocities in the edges of the disk. Ultrasonic velocities in the thickness direction were also measured as a function of location using dry-coupling transducers ; the results were consistent with the densification behavior. However, velocities in the in-plane directions (circumferential and radial) seemed to be affected more by the relative contents of fabric and chopped fiber, and less by the void content.

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Performance evaluation of lattice girder depending on the quality of steel (강재 품질에 따른 격자지보재의 성능평가)

  • Jung, Hyuk-Sang;Shin, Young-Wan;Song, Ki-Il;Shin, Jong-Ho
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.18 no.2
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    • pp.165-173
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    • 2016
  • This paper dealt with contents on the performance evaluation of standardized steel and non-standardized steel of lattice girder. Lattice girder is arch type tunnel supports made of structural steel bar and it is girder used to ensure the stability of tunnel by suppressing any transformation of ground as much as possible during tunnel excavation. The performance evaluation of lattice girder can be conducted through bending strength test, tensile strength test and tunnel standard specification specifies that welding structural steel with over 500MPa yield strength shall be used. However, it is difficult to distinguish visually between standardized steel and non-standardized steel onsite if low-quality structural steel is used. Accordingly, this paper conducted performance evaluation of standardized steel and non-standardized steel of lattice girder to point out the issue of deteriorated yield strength of non-standardized steel, while proposed a method of verifying yield strength onsite.

The experimental study for hemodynamic changes in the heart-lung preparatio by autoperfusion (자가관류법에 의한 체외심폐의 혈역학적 변동에 관한 실험적 연구)

  • 한승세
    • Journal of Chest Surgery
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    • v.22 no.2
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    • pp.179-190
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    • 1989
  • The experimental study for extracorporeal preservation of the heart-lung preparation by autoperfusion system was performed in 10 dogs. Under intravenous Pentothal endotracheal anesthesia bilateral thoracotomies were performed. A 24F cannula connected to a plastic reservoir bag located 100 cm above the level of the heart was introduced into the aortic arch. Left subclavian, innominate artery, and descending aorta were ligated and divided. Both vena cavae were ligated and divided after the bag was half filled with blood. A 24F catheter inserted into right atrium and connected to the plastic bag in order to keep constant the preload. The thoracic trachea was intubated and the lungs were ventilated. The heart-lung preparations were removed en bloc and floated in a $34^{\circ}C$ bath of Hartmann solution. The preparations were observed for from 2 hours to 8 hours, with the average of 5.2 hours. Hemodynamic and hematologic variables were measured during preharvest and autoperfusion. The pH revealed severe respiratory alkalosis due to very low $PaCO_2$ during autoperfusion ; $PaO_2$ remained constant for 130-140 mmHg; $A-aDO_2$ increased markedly. The static inspiratory pressure [SIP] at late autoperfusion [6hr] increased significantly as compared with at early autoperfusion [2hr]. There was no difference between white blood cell counts from right atrium and those of left atrium. Heart rates remained constant for 110-120/min; cardiac outputs maintained to approximately 0.6L/min; mean aortic pressures, 75 mmHg; mean pulmonary arterial pressures, 15-18 mmHg; mean right atrial pressures, 9-13 mmHg; mean left atrial pressures, 12 mmHg lower than those of right atrium. Serum Na maintained with normal range during autoperfusion; K increased significantly; Ca decreased progressively. Hemoglobin and hematocrit decreased significantly during autoperfusion. The study demonstrated that stable hemodynamics could be maintained throughout the experiment and the preparation of the lung seemed to be inadequate, especially after 3-4 hours, such as high $A-aDO_2$, increased SIP, and scattered atelectasis and edema in their gross appearances.

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Presumption of low hack pain and symptoms for surgical treatment (요통의 예후와 수술적응증 판단)

  • Lee, Geon-mok
    • Journal of Acupuncture Research
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    • v.18 no.2
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    • pp.237-244
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    • 2001
  • Back pain has plagued humans for many thousands of years. The treatment of back pain is divided into operative treatment and conservative treatment. It is reported that cure rate of conservative treatment is 80~90 percent. Generally, the treatment of oriental medicine is mostly conservative treatment. But, surgery should not be used as a last resort in treatment; it is just one of many treatment options for various spinal conditions. In some instance, it can be to preferred choice; in other situations, alternative therapies may be superior. Selections of the operation in HIVD 1. Acute disc herniations with a protracted significant component af back pain. 2. Chronic disc degeneration with significant back pain and degeneration limited to one or two disc levels. 3. Sugical instability created during decompression. 4. The presence of neural arch defects coincident with disc disease. 5. Symptamatic and radiographically demonstrable segmental instability. Selections of the operation in stenosis 1. If it does not slowly progress in physical therapy and other nonoperative measures, many of these patients may ultimately need surgical decompression. 2. Absolute stenosis in an impression of CT, MRI.(under 10mm) 3. In patients with established symptoms of .neurogenic claudication. 4. In patients with bad influence of neurogenic derangement.(strength, sensory) Selections of the operation in spondylolisthesis 1. Persistence or recurrence of major symptoms for at least one year despite activity modification and physical therapy. 2. Tight hamstrings, persistently abnormal gait, or postural deformities unrelieved by physical therapy. 3. Sciatic scoliosis. 4. Progressive neurologic deficit. 5. Progressive slipping beyond 25 or 50 percent, even when asymptomatic. 6. A high slip angle (40 to 50 degrees) in a growing child, since it is likely to be associated with further progression and deformity. 7. Psychologic problems attributed to shortness of trunk, abnormal gait, and postural deformities characteristic of more severe slips.

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