• Title/Summary/Keyword: Low Activity

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Metabolic Role of Glyoxylate on the Biosynthesis of Serratia marcescens Purine Nucleoside Phosphorylase (Serratia marcescens Purine Nucleoside Phosphorylase의 생합성에 대한 글리옥실산의 대사적 역할)

  • 방선권
    • The Korean Journal of Food And Nutrition
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    • v.12 no.1
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    • pp.43-49
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    • 1999
  • The effects of purine catabolites in growth media on the Serratia marcescens purine nucleoside phos-phorylase activity were examined. The enzyme activity was decreased above 60% by guanosine(5 to 15mM). The enzyme activity was not affected at low concentration of inosine (0.1∼1mM). The en-zyme activity was decreased approximately by 40∼50% in the presence of high concentrations of aden-osine hypoxanthine and xanthine (5∼15mM) but was not affected at low concentration of adenosine hypoxanthine and xanthine (0.1∼0.5mM). However the enzyme activity was increase by 20% with low concentrations of uric acid(0.5mN). but was decreased by 80% with high concentrations of same purine catabolite (15mM). Also the enxzyme activity was increased by 20% with low concentrations of glyoxylate (0.5mM) final degradative product of uric acid but was decreased by 30∼50% with high con-centrations of glyoxylate (3∼15mM). The enzyme activity was decreased approximately by 20% by the simultaneous addition of inosine hypoxanthine and uricacid at 5mM each whereas it was increased by 22 and 33% by the combination of inosine and uric acid three purine catabolites at 0.5mM respectively These data suggest that S. marcescens purine nucleoside phosphorylase is positively regulated by a glyox-ylate concentration and then may play a regulatory role in a purine catabolism.

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Electromyographic studies on the masseter and temporal muscles during exchange of the deciduous teeth (유치 교환기의 교근 및 측두근의 근전도 연구)

  • Lee, Jong-Heun
    • The Korean Journal of Physiology
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    • v.3 no.1
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    • pp.33-44
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    • 1969
  • Electoromyographic studies were performed on the action of the muscles of the temporomandibular joints following exfoliation of the deciduous teeth. The subjects examined, being 50 children. between the age of 6 and 13 years, divided into 5 groups. They were; 1) Deciduous dentition were complete in the first group. 2) Deciduous incisors were missing in either upper or lower jaw in the second group. 3) Deciduous canine and molars were missing in the left side of either upper or lower jaw in the third group. 4) Deciduous canine and molars were missing in the right side of either upper or lower jaw in the fourth group. 5) Permanent dentition completed in the fifth group(except third molars). Electromyogram was recorded with 4 channel polygraph (Grass model VII modified for 7P3). Electrodes which were the cup-typed gold discs, 9 millimeters in the diameter, were located on the anterior, middle and posterior lobes of the temporal muscles, and also on the superficial and deep layers of the masseter muscles. Paired electrodes were held by electrode cream so that they were pressed on the skin surface at right angle, adhesive tape being used to anchor them. The distance of the pair electrodes was about 5 millimeters. The results obtained were as follow: 1) In rest position of mandible; All groups showed slight, electrical activities in the muscles involved, but in the middle lobe of temporal muscle they were slightly higher. 2) In molar occlusion of mandible; High activity-anterior lobe of temporal muscle and superficial layer of masseter muscle. Moderate activity-deep layer of masseter muscle. Low activity-middle and posterior lobes of masseter muscle. There were no differences among the first, the second and the fifth groups. In the third group the muscle activity was weaker than that of the right, and in the fourth group opposite characteristics was revealed. 3) In incisal bite of mandreble; Hight activity-superficial layer of masseter muscle. Modertae activity-deep layer of masseter muscle. Low activity-anterior, middle and posterior lobes of temporal muscle. The first, the third, the fourth and the fifth groups showed no differences but the second group showed less activity than those of others. 4) In protrusion of mandible; High activity-deep layer of masseter muscle Moderate activity-superficial layer of masseter muscle. Low activity-anterior, middle and posterior lobes of temporal muscle. In the first, the fourth and the fifth groups, there were no differences in the activities, but the second group showed less activity than the others. 5) In retrusion of mandible; High activity-deep layer of masseter muscle. Moderate activity-superficial layer of masseter muscle. Low activity-anterior, middle and posterior lobes of temporal muscle. In the first, the third, the fourth and the fifth groups, there were no differences but the second group showed less activity than the others. 6) In lateral excursion of the mandible (either direction); High activity-posterior lobe of temporal muscle. Moderate activity-anterior and middle lobes of temporal muscle. Low activity-superficial and deep layers of masseter muscle. The muscle action potentials were weaker than those of the right side in the third group and vice ver'sa in the fourth group. 7) In chewing movement; Temporal muscle activities were higher than those of masseter, especially in the middle lobe of temporal muscle the activity was highest. Right side muscle activities were higher than those of the left in the third group and, on the contrary, the left side was dominant over the right in the fourth group.

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Influence of Physical Activity on Smoking Experience and Smoking Intensity in Korean High School Students (신체활동이 고등학생의 흡연 경험 및 흡연 강도에 미치는 영향)

  • Ra, Jin Suk;Cho, Yoon Hee
    • Journal of the Korean Society of School Health
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    • v.27 no.3
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    • pp.181-188
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    • 2014
  • Purpose: The purpose of this study was to investigate the influence of physical activity on smoking experience and smoking intensity in Korean high school students. Methods: This cross sectional study used secondary data from the 2013 Adolescent Health Behavior Online Survey. A total of 35,905 high school students were included in the study. Logistic regression was used for analysis of the influence of moderate and vigorous physical activity on smoking experience in a month and smoking intensity. Results: Adolescents with low (Adjusted OR: 1.242, 95% CI: 1.075~1.436) and moderate level (Adjusted OR: 1.094, 95% CI: 1.005~1.189) of moderate physical activity had more smoking experience than reference group, high level of physical activity. Also, smoking experience was more prevalent adolescents with low (Adjusted OR: 1.191, 95% CI: 1.064~1.333) and moderate level (Adjusted OR: 1.134, 95% CI: 1.039~1.237) of vigorous physical activity. Heavy smoking was more prevalent among adolescents who had low level of vigorous physical activity (Adjusted OR: 1.912, 95% CI: 1.347~2.712). Conclusion: Based on the results of this study, physical activity has significant influence on smoking experience and smoking intensity. Therefore, physical activity should be included smoking cessation and smoking prevention program for High School Students.

Tritium( $^3$H) Activity Measurement by the Liquid Scintillation Counting Method

  • Hwang, Sun-Tae;Oh, Pil-Jae;Lee, Min-Kie;Kim, Wi-Soo
    • Journal of Korean Society for Atmospheric Environment
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    • v.10 no.E
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    • pp.299-302
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    • 1994
  • At a nuclear power plant, environmental radioactivity monitoring is routine work for the radiation safety management For the environmental monitoring of tritium($^3$H) activity in water sampled liquid scintillation counting( LSC) method is applied to measure low- energy beta activity from tritium in the samples. The $^3$H activity is measured using the BECKMAN 5801 system at the KRISS( Korea Research Institute of Standards and Science) for evaluating the lower limits of detection( LLD) of $^3$H measurement and the measuring capability of low-level $^3$H activity at four nuclear Power Plant sites. The LSC systems used for low-level $^3$H activity measurements at the nuclear Power Plants are confirmed to satisfy throughout an intercomparison study under the experimental arrangements by the KRISS.

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Socio-demographic Determinants of Low Physical Activity in Peruvian Adults: Results of a Population-based Survey Performed in 2017-2018

  • Hernandez-Vasquez, Akram;Vargas-Fernandez, Rodrigo
    • Journal of Preventive Medicine and Public Health
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    • v.54 no.6
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    • pp.461-470
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    • 2021
  • Objectives: The objective of this study was to determine the prevalence of low physical activity (PA) in Peruvian adults and to identify associated factors. Methods: An analytical study was performed using data from the 2017-2018 Nutritional Food Surveillance by Life Stages survey. The outcome variable was low PA (yes or no), assessed using the International Physical Activity Questionnaire-short form. Prevalence ratios were estimated as a measure of association. Results: Among the 1045 persons included in the analysis, the age-standardized prevalence of low PA was 61.9%. The adjusted model showed that being female and migrating from a rural to an urban area in the last 5 years were associated with a higher probability of having low PA than males and individuals who had not migrated, while residing in rural highlands and jungle areas was associated with a reduced probability of having low PA compared to people residing in other geographic domains. Conclusions: Being a female and migration from a rural to an urban area in the last 5 years were associated with a higher likelihood of having low PA. Therefore, promotion and prevention strategies related to PA are required, especially in the female and migrant populations.

Criterion Development of 4 Activity Levels for Estimated Energy Requirement Calculation for Primary School Students (초등학생(고학년)의 에너지필요추정량 산출을 위한 4단계 신체활동단계의 간편 판정법 연구)

  • Kim, Mi-Jeong;Na, Hyeon-Ju;Kim, Young-Nam
    • Korean Journal of Community Nutrition
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    • v.16 no.3
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    • pp.307-314
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    • 2011
  • The purpose of this study is finding the easy way of 4 categories activity level confirmation for estimated energy requirement calculation. Total of 386, 5th and 6th grade primary school students participated. The time spent on 7 kinds of activity were collected for 1 day by the internet program developed. Judged by the activity coefficient, sedentary were 6.7% and 5.1%, low active 33.2% and 40.4%, active 43.8%, and45.5%, and very active 16.3% and 9.0% for boy and girl, respectively. The highest and significant correlation coefficient between activity coefficient and time spent on activities shown were 0.339 in commute activity for boys, and 0.466 in leisure for girls. The sensitivity of the sedentary conformation by commute hour for boys was 0.79, and that of very active was 0.56. The sensitivity of the sedentary conformation by leisure hour for girls was 0.67, and that of very active was 0.63. The sensitivity of low active and active by 7 different types of activity was quite low, 0.04~0.37. The exact agreement of activity level conformed by easy way developed was 30.8% and 33.7%, for boys and girls, respectively. More accurate way to identify 4 categories activity level needs to be developed, especially sensitive to conformation of low active and active levels.

Impediment in Activity of Daily Living and Social Support for Rural Elderly Farmers Undergoing Nerve Block due to Low Back Pain (만성요통으로 신경차단술을 받은 농촌 노인들의 사회적 지지와 일상생활 활동장애에 관한 연구)

  • Choi, In Young;Hwang, Moon Sook
    • Research in Community and Public Health Nursing
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    • v.30 no.2
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    • pp.206-216
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    • 2019
  • Purpose: This study is to investigate the low back pain, social support, impediment in daily living activities and to identify factors affecting impediment in elderly farmer' daily living activities. Methods: The participants were 128 elderly farmers who had received nerve block. Data were collected using a structured questionnaire from February to March, 2018. They were analyzed using t-test, ANOVA, pearson's correlation coefficient, and linear multiple regression. Results: The score of low back pain was $6.27{\pm}1.69$ (10 points), that of social support $2.92{\pm}0.76$ (1~5 points), and that of impediment in activity of daily living $2.01{\pm}0.82$ (0~5 points). Factors affecting impediment in activity of daily living were found to include age (p=.017), daily hours of farm work (p<.001), fear for the nerve block (p<.001), low back pain (p<.001), and social support (p<.001); the explanatory power of these variables was 58.8%. Conclusion: This study has found the controllable factors affecting impediment in activity of daily living among the rural elderly engaging in farm work include low back pain, social support, and daily farming hours. Therefore, to reduce impediment in activity of daily living among them, it is necessary to develop nursing interventions that can improve impediment in activity of daily living through reduction of daily farming hours using local resources. It is also desirable to improve their health status by reducing low back pain, and develop and apply social supports with health education programs that fit the local resources and the needs of the rural elderly.

A Study on the Formation of Aluminide Coating on KM 1557 Alloy by Pack Cementation Process (Pack Cementation법에 의한 KM 1557 합금의 알루미나이드 코팅층 형성에 관한 연구)

  • Yoon, Jin-Kook;Yoo, Myoung Ki;Choi, Ju;Kim, Jae-Soo
    • Analytical Science and Technology
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    • v.6 no.2
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    • pp.167-180
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    • 1993
  • The effects of coating variables on the formation of aluminide coating layer with good oxidation resistance on the strongest hot-forged superalloy in the world, KM 1557 developed at KIST by pack cementation process were studied. Pack aluminizing were performed by high-activity process with pure aluminium powders and by low-activity process with codep powders. For high-activity process, Al deposition rate, growth rate of coating layer, and cross-sectional microstructures were influenced by the species and additive amounts of activators and the additive amounts of pure aluminium powders. For low-activity process, Al deposition rate, growth rate of coating layer, and the cross-sectional microstructures were not influenced by the species but additive amounts of activators. Surface structures of coating layer were influenced by the species of activators. Regardless of aluminium activity, Al deposition rate was proportional to the square root of time and parabolic rate constants were different with the species of activators. The activation energy for deposition of aluminium was different with the species of activators for high-activity process. Regardless of the species of activators, the activation energy for deposition of aluminium was 12~14 Kcal/mole for low-activity process.

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Biological Activities of Low Molecular Weight Substances Fractionated from the Seasoned and Smoked Products of Skipjack Tuna (Euthynus pelamis) (가다랑어 훈연조미제품 유래 저분자물질의 생리활성)

  • LEE Jung Min;CHOI Geun Pyo;WON Moo Ho;KIM Sang Moo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.38 no.4
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    • pp.219-225
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    • 2005
  • We studied the anticancer, antioxidative, ACE inhibitory, antithrombic, and cerebral ischemia inhibitory activities, of low molecular weight substances fractionated from the seasoned and smoked products of skipjack tuna (Euthynus pelamis). Low molecular weight substances fractionated from the liquid extract of seasoned and smoked skipjack tuna powder showed 7 peaks on gel permeation chromatography. Anticancer activity was the highest at Peak 3 $(54.23%)$ followed by Peak 4 $(41.58\%)$. The potency order of antioxidative activity was the highest at Peak 3 $(94.14\%)$ followed by Peak 2 $(82.07\%)$ and Peak 5 $(81.24\%)$. ACE inhibitory activity was the highest at Peak 3 $(67.27\%)$ followed by Peak 5 $(45.62\%)$. But there was weak anti thrombotic effect (PT and APTT) in the low molecular weight substances of the seasoned and smoked products of skipjack tuna. Cerebral ischemia inhibitory activity was the highest at Peak 3 $(80.0\%)$ followed by Peak 5 $(40.0\%)$.

Interactions between Hyaluronic Acid, Lysozyme, Peroxidase, and Glucose Oxidase in Enzymatic Activities at Low pH

  • Kim, Bum-Soo;Kim, Yoon-Young;Chang, Ji-Youn;Kho, Hong-Seop
    • Journal of Oral Medicine and Pain
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    • v.39 no.4
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    • pp.127-132
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    • 2014
  • Purpose: Many substances in saliva or oral health care products interact with each other. The aim of this study was to investigate interactions between hyaluronic acid (HA), lysozyme, peroxidase, and glucose oxidase (GO) in enzymatic activities at low pH levels. Methods: HA (0.5 mg/mL), hen egg-white lysozyme (HEWL, $30{\mu}g/mL$), bovine lactoperoxidase (bLPO, $25{\mu}g/mL$), and GO ($50{\mu}g/mL$) were used. The influences of HA, bLPO, and GO on HEWL activity were determined by measuring the turbidity of a Micrococcus lysodeikticus suspension. The influences of HA and HEWL on bLPO activity were determined by the NbsSCN assay, measuring the rate of oxidation of 5-thio-2-nitrobenzoic acid (Nbs) to 5,5'-dithiobis(2-nitrobenzoic acid) $(Nbs)_2$. The influences of HA and HEWL on GO activity were determined by measuring oxidized o-dianisidine production. All experiments were performed at pH 4, 5, and 6. Results: HA and GO did not affect the enzymatic activity of HEWL at pH 4, 5, and 6. bLPO enhanced the enzymatic activity of HEWL at pH 5 (p<0.05) and pH 6 (p<0.05) significantly. The enzymatic activity of bLPO was not affected by HA and HEWL at pH 4, 5, and 6. HA and HEWL did not affect the enzymatic activity of the GO at pH 4, 5, and 6. Conclusions: Peroxidase enhances lysozyme activity at low pH, otherwise there were no significant interactions in enzymatic activities between HA, lysozyme, peroxidase, and GO at low pH levels.