• The Journal of Korean Society of Virology
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• 제29권4호
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• pp.211-219
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• 1999

Most of the currently licensed viral and bacterial vaccines produced in the world are in state of antigen suspension and the immunogenicity of vaccines could be maintained for one or two years only by keeping in the refrigerator, but without refrigeration vaccines would easily lose their immunogenicites. In this study, as a step to develope the method of increasing the stability of vaccines and maintaining the immunogenicity of vaccines for a long time at room temperature or higher temperature, trehalose, glucose and lactose at different concentration were added into the Hantaan virus vaccines and then kept at $37^{\circ}C$ for 12, 24, 48 hours and at room temperature for seven days respectively. Treated vaccines were then inoculated respectively into ICR mice and the titers of antibody against the antigen of Hantaan virus from the mice sera were evaluated. Vaccine without sugar lost immunogenicity completely in 24 hour at $37^{\circ}C$, but the vaccines containing trehalose could maintain some of the immunogenicity even after exposure at $37^{\circ}C$ for 48 hours and the best concentration of trehalose for maintaining the immunogenicities of vaccines was $7.5{\sim}10$ percent. The results suggest that addition of trehalose could increase the stability of Hantaan virus vaccine.

• Advances in pediatric surgery
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• 제20권2호
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• pp.23-27
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• 2014

Purpose: Laparoscopic hernia repair in children is still controversial. The aim of this study was to report our long-term results of the laparoscopic hernia technique, which is based on the same surgical principles as conventional open herniotomy. Methods: Five hundred fourteen pediatric patients with inguinal hernia were included in this study under informed consent. All patients underwent a laparoscopic technique of sac transection and intracorporeal ligation. The asymptomatic contralateral inguinal ring was routinely explored and repaired if a patient had patent processus vaginalis on the contralateral side. Patients were prospectively followed for 5 years. Those who were lost to follow-up were excluded from the study. Perioperative complications and recurrences were evaluated. Results: The mean follow-up period was 29 months. Mean operation time was 27.5 minutes. Forty one percent of the patients had contralateral patent processus vaginalis. Only one hernia recurred (0.19%). We had one case of contralateral metachronous hernia (0.21%) during follow-up period. Conclusion: The long-term follow-up results of our study revealed that laparoscopic hernia sac transection and ligation can be a safe and effective alternative for conventional herniorraphy.

• The Journal of the Korea institute of electronic communication sciences
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• 제9권6호
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• pp.633-640
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• 2014

This paper is what accident in sea have been produced as lost themselves life and property about 600~700times at every years. It was analyzed that the collision accident is highest rank by 37% among the marine accidents and the fishing vessel is highest by 58% in these collision accidents and also the small fishing boat under 20tons is highest by 27% on them. Over the half of thecollision accidents by 56% they couldn't find each other to just before the collision situation. Therefore this was induced to experiment on a national basis that the role of communication of ship is to move from lose themselves life and property.

• The Korean Journal of Community Living Science
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• 제22권4호
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• pp.637-653
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• 2011

Over the last 20 years, women's development has been ambiguous. According to Freud, the mother-daughter relationship has been considered as an essential component of women's development. This study investigated how the mourning experience from daughters who were separated from their mothers by death offers any meaningful idea to women's life. For Hermeneutic phenomenology, researchers collected data from three women who have lost their mothers through in-depth interviews and drawing pictures with each of them. As a result, this study found that daughters started to fight with their mothers' death from the moment when they were informed. They also experienced a symbolic death until the moment of their mothers' death and even after the confirmation of their mothers' death. Daughters experienced symbolic death, both emotionally and physically as well as familiar experiences with their mothers through the repeated confirmation of death. However, these experiences encouraged daughters to adapt to the reality that was the absence of their mothers through the processes such as "Reflection," "Living in the Center of My life," and "Another Embrace." Through this new perspective, attempts, and relationships, daughters form a new identity and experience 'rebirth'. These daughters' changes were paradoxically strengthened through their resistances towards changes of reformation of themselves.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제18권1호
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• pp.55-59
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• 2015

Gastroesophageal reflux disorder (GERD) is the most common esophageal disorder in children. Achalasia occurs less commonly but has similar symptoms to GERD. A nine-year old boy presented with vomiting, heartburn, and nocturnal cough. The esophageal impedance-pH monitor revealed nonacidic GERD (all-refluxate clearance percent time of 20.9%). His symptoms persisted despite medical treatment for GERD, and he was lost to follow up. Four years later, he presented with heartburn, solid-food dysphagia, daily post-prandial vomiting, and failure to thrive. Endoscopy showed a severely dilated esophagus with candidiasis. High-resolution manometry was performed, and he was diagnosed with classic achalasia (also known as type I). His symptoms resolved after two pneumatic dilatation procedures, and his weight and height began to catch up to his peers. Clinicians might consider using high-resolution manometry in children with atypical GERD even after evaluation with an impedance-pH monitor.

• Journal of Korean Society of Industrial and Systems Engineering
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• 제23권56호
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• pp.65-85
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• 2000

Industrial accidents have been consistently increased in terms of medical costs, lost work days, and incidence rates every year in Korea. Since the infrastructure of the industry changed shifts rapidly from 1980s in the developing countries such as South Korea, the nature and magnitude of the industrial accidents have also undergone a major shift. The situation is especially severe in small-to-medium sized industry(SMI). This article reports the development of a systematic evaluation system of risk factors specifically for the SMIs. The new approach introduced by this article is geared to the systematic identification and evaluation of the injuries from power press machines using the Analytic Hierarchy Process with the key evaluation data generated and evaluated by the employees on site. A total of 21 companies was studied and surveyed using the hierarchical structures of the cause-effect relationship of the mechanical injuries and their countermeasures. For the relative weighting of each risk factor, separate questionnaire survey was conducted for the selected workers from each company who had worked for more than 10 years in press work. Most participants (48 out of 62) replied that human attributes were the most significant factors for mechanical injuries fellowed by administration, machine, and work environment factors. The result also showed that the self-motivated risk assessment and safety enhancement activities would be an effective and efficient way of managing the risk factors in the SMIs.

• Journal of muscle and joint health
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• 제26권2호
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• pp.72-80
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• 2019

Purpose: This study was done to explore the lived experiences in older Korean women with early stage of Parkinson's disease. The research question was "What is the meaning and nature of the older women's experiences who were diagnosed with Parkinson's disease?" Methods: In this study, we adopted van Manen's hermeneutic phenomenological approach to find the lived experiences of older women diagnosed with Parkinson's disease. Six older women diagnosed with Parkinson's disease within five years participated, and data were collected through in-depth interviews. Results: Five fundamental lifeworld themes and seven subthemes emerged from the data. The first theme of corporeality had three subthemes: 'being shocked by an unexpected diagnosis', 'fewer things can be done due to the illness' and 'lost my prettiness'. The second theme representing relationality was 'hiding the illness because of others' whispering'. The temporality theme was 'fear of symptom aggravation'. The spatiality theme was 'being placed in a blind spot of information'. The last existential theme of material had 'obsession with drugs'. Conclusion: The results of this study provide an in-depth understanding of older womens experiences of living with Parkinson's disease. The findings can help develop interventions specific to these group of women to provide sufficient emotional support and accurate information.

• Journal of Korean Public Health Nursing
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• 제33권2호
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• pp.214-227
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• 2019

Purpose: This study examined the socio-demographic factors, the disaster related factors, the physical health related factors and the psychological factors of older adults exposed to natural disaster and these factors may possibly cause the occurrence of PTSD. Methods: A cross-sectional study was designed using the secondary data from the 3rd Disaster Victims Panel Survey (2012-2017). The data from 1,397 disaster victims were analyzed using descriptive statistics and logistic regression analysis. Results: Compared with the younger adult disaster victims, the elderly were more likely to have symptoms of PTSD (15.0% vs. 12.1%). Factors such as the number of years since being exposed to the disaster, anxiety, depression and social adjustment were significantly associated with occurrence of PTSD for both older and younger adults. Female gender was the additional risk factors for the older adults, while marital status, income, having witnessed another person's injury or death, and having lost a home were associated with the occurrence of PTSD. Conclusion: The elderly were more likely to develop PTSD as compared with younger adults. More targeted post-disaster mental health services to the elderly with the symptoms of depressive, anxiety and impaired social adjustments, should be provided to improve their mental health.

• The Journal of Korean Medical History
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• 제31권2호
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• pp.1-8
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• 2018

To prepare for war against the Qing, King Hyojong and Song Si-Yeol (Uam, 1607~1689) of Joseon compiled the "Sambang", a set of medical books by utilizing the experience of famous doctors from 8 provinces of Korea. After the compilation, the disciples of Uam compiled a book called "Sambang-chwaryo", a summary of the "Sambang". Although these two books have been mentioned several times in records, the actual books were known to be lost. However, a promotional article for "Sambang-chwaryo" in the 1940s edition list of the Haengnim publishing house, who tried to publish but failed, has been discovered, and a handwritten copy of the book from the editor's descendant has been obtained a few years ago. By acquiring this proofread copy, it has become possible to grasp the actual contents of the "Sambang-chwaryo". Moreover, the whole contents have been translated into modern Korean and released to the public. In this paper, we review the bibliographic information of this book and try to understand the purpose, process, author and various versions of the compilation and its history.

• Journal of the Architectural Institute of Korea Planning & Design
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• 제35권1호
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• pp.63-72
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• 2019

The purpose of this study is that investigated the characteristics of integral planning related factors using the history and culture of Mojiko. It is a small city that has been urbanized after the opening of the port for logistics transportation in the modern period of Japan. As the function of the logistics city, which is the factor of the expansion of the town, declined, Mojiko applied the retro concept to the harbor which has lost its popularity due to the regional characteristics of the city to increase and revitalize local visits. Mojiko has steadily promoted the retro style of landscape and town development over 30 years, focusing on 18 Historical buildings and modern infrastructure. We analyzed characteristics of integrated urban planning include the regulation, landscape institution. Moreover, we suggest the result of the designation process of a core scenery maintenance district and the components of the plan after the designation analysis and provide essential data for revitalizing the field based on the historic city for the cultural establishment and beautiful town in the future. And deliver vital data to reviving the area based on the historical city culture establishment and beautiful town in the future.