• Proceedings of the Korean Operations and Management Science Society Conference
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• 2007.11a
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• pp.90-96
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• 2007

In multi-location inventory systems, lost sales due to stockout decreases not only retailers' profit but also whole supply chain's profit. Transshipment between retailers has been considered to be a major solution to the stockout problem, and many supply chains implement transshipment coalition among retailers. However, in practical situations, retailers occasionally refuses to accept the transshipment requests, mainly because they concern the future stockout possibilities of their own. Thus, the objective of this research is to analyze the effect of retailers' interaction under the transshipment coalition environment based on the simulations, and to provide effective policies to promote retailers' transshipment cooperation. Policies using penalty and incentive scheme are proposed, and it is shown that using proposed policies both the retailers' and the headquarter's profit can be increased.

• The Journal of Korean Physical Therapy
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• v.6 no.1
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• pp.155-161
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• 1994

Joint mobilization refers to techniques that are used to treat joint dysfunction such as when there is stiffness reversible joint hypomobility, or pain. Currently there are several schools of thought and treatment techniques that are popular in the United States. and leading practitioners and educators are attempting to blend common points to yield more uniform treatment from the various approaches. In order to effectively use joint mobilization for treatment, the practitioner must know and be able to evaluate the anatomy, arthrokinematics, and pathology of the neuromusculoskeletal system and to recognize when the techniques are indicated or when other stretching techniques would be more effective for regaining lost motion. Indiscriminate use of joint mobilization techniques when tot indicted could lead to potential harm to the patient's joints.

• Journal of Korean Society for Quality Management
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• v.30 no.3
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• pp.53-65
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• 2002

This paper studies an economic manufacturing quantity (EMQ) model with two types of failures and planned preventive maintenance of the production facility. One is a type I (major) failure which should be corrected by a failure maintenance and the other is a type H (minor) failure which can be minimally repaired without interrupting the production run. The objective is to determine the lot size and preventive replacement policy minimizing the long-run expected cost per unit time. We consider a control policy with a constant production lot size and preventive maintenance after completing n production runs. It is assumed that both preventive and failure maintenance times are random and the demand arriving during a stock-out period is lost. An expression for the expected cost per unit time is obtained in the general case. A special case is discussed and numerical results are provided.

• BMB Reports
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• v.32 no.5
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• pp.440-444
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• 1999

Membrane lipid peroxidation processes yield reactive aldehydes that may react with copper,zinc superoxide dismutase (Cu,Zn SOD), one of the key antioxidant enzymes against oxidative stress. We investigated this possibility and found that exposing Cu,Zn SOD to malondialdehyde (MDA) or 4-hydroxynonenal (HNE) caused the loss of dismutase activity, cross-linking of peptides, and an increase in protein oxidation, reflected by the increased level of carbonyl groups. When Cu,Zn SOD that had been exposed to MDA or HNE was subsequently analyzed by amino acid analysis, histidine content was found to be significantly lost. Both MDA-and HNE-treated Cu,Zn SOD were resistant to proteolysis, which may imply that damaged proteins exist in vivo for a longer period of time than the native enzyme. The lipid peroxidation-mediated damage to Cu,Zn SOD may result in the perturbation of cellular antioxidant defense mechanisms, and subsequently lead to a pro-oxidant condition.

• BMB Reports
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• v.31 no.4
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• pp.377-383
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• 1998

Thioltransferase, also known as glutaredoxin, was purified from Chinese cabbage (Brassica campestris ssp. napus var. pekinensis) by a combination of ion-exchange chromatography and gel filtration. Its purity was confirmed by SDS-polyacrylamide gel electrophoresis and its molecular weight was estimated to be about 12,000 which is comparable with those of most known thioltransferases. The enzyme utilizes 2-hydroxyethyl disulfide, S-sulfocysteine, ${\alpha}-chymotrypsin$, insulin, and trypsin as substrates in the presence of reduced glutathione. The enzyme has Km values of 0.03-0.97 mM for these substrates. It appeared to contain dehydroascorbate reductase activity. The pH optimum of the enzyme was 8.5, when 2-hydroxyethyl disulfide was used as a substrate. It was greatly activated by reduced glutathione. Its activity was not significantly lost when stored at high temperature, indicating its thermostable character. It may play an important role in thiol-disulfide exchange in plant cells.

• Korean Institute of Interior Design Journal
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• v.14 no.2 s.49
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• pp.20-28
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• 2005

This paper investigates that the ambiguity of the boundary between interior space and exterior space in architecture appears universally in history and reveals the various aspects of ambiguous boundary in architecture. The space is formed by the relationship with the surroundings and the boundary of two opposite spaces is apt to be ambiguous according to lots of complex factors. Before Modern Architecture the boundary of interior and exterior space had a tendency to be ambiguous by modifying compositional method of material boundary, that is semi interior-exterior space, the reversion of interior and exterior space and space in space. After Modern Architecture the meaning of physical boundary in space is lost along with dissolution of boundary over the society and the boundary of space comes to be dematerialized by the technology and the change of space perception. The phenomenon of deconstruction in spacial boundary accelerate increasingly according to fluid space, mutually interpenetrated space, visual transparency and adjustment of layers. And contemporary technology is collapsing the meaning itself of space division fundamentally.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.9 no.1
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• pp.30-37
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• 2000

In this paper rapid prototyping and precision casting technology have been developed for the manufacturing of inlet gear box of an airplane, Rapid prototyping is a new prototyping technology that produces complicated parts directly from three-dimensional CAD data with a high efficiency and has been extensively applied to various manufacturing processes. In the present work Selective Lase Sintering(SLS) system is utilized in order to manufacture prototype of the inlet gear box. Prototyping technology using SLS is also investigated from the viewpoint of accuracy. Using the SLS master the casting products are manufactured through several processes such as : vacuum casting lost wax shell casting and investment cast-ing. The shrinkage characteristics of wax and cast iron in the casting procedures are considered and then reflected to the design procedure so that the accuracy of the product is improved consequently.

• Journal of Preventive Medicine and Public Health
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• v.50 no.4
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• pp.217-227
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• 2017

In terms of years of life lost to premature mortality, cancer imposes the highest burden in Korea. In order to reduce the burden of cancer, the Korean government has implemented cancer control programs aiming to reduce cancer incidence, to increase survival rates, and to decrease cancer mortality. However, these programs may paradoxically increase the cost burden. For examples, a cancer screening program for early detection could bring about over-diagnosis and over-treatment, and supplying medical services in a paternalistic manner could lead to defensive medicine or futile care. As a practical measure to reduce the cost burden of cancer, appropriate cancer care should be established. Ensuring appropriateness requires patient-doctor communication to ensure that utility values are shared and that autonomous decisions are made regarding medical services. Thus, strategies for reducing the cost burden of cancer through ensuring appropriate patient-centered care include introducing value-based medicine, conducting cost-utility studies, and developing patient decision aids.

• Journal of the Korean Society of Radiology
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• v.2 no.2
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• pp.17-21
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• 2008

Image quality is improved if the high frequency domains of boundary surface are made distinct. We suggested a method of correcting indistinct defects in ultrasonic images resulting from dynamic imaging. According to the results of the experiment, boundaries in input ultrasonic images became distinct. However, we need to solve the problem that information on pixels of low signal intensity adjacent to boundaries is lost because high-frequency components in the boundaries are strong.

• The Plant Pathology Journal
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• v.33 no.6
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• pp.597-601
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• 2017

The clpks18 gene was first cloned and identified in Curvularia lunata. It contains 6571 base pairs (bp) and an 6276 bp open reading frame encoding 2091 amino acids. The ClPKS18 deletion mutant displayed an albino phenotype, and almost lost the ability to product 5-(hydroxymethyl) furan-2-carboxylate (M5HF2C) toxin, implying that clpks18 gene in C. lunata is not only involved in 1,8-dihydroxynaphthalene melanin synthesis, but also relatively associated with M5HF2C toxin biosynthesis of the pathogen. The pathogenicity assays revealed that ${\Delta}ClPKS18$ was impaired in colonizing the maize leaves, which corresponds to the finding that ClPKS18 controls the production of melanin and M5HF2C in C. lunata. Results indicate that ClPKS18 plays a vital role in regulating pathogenicity of in C. lunata.