• Nuclear Engineering and Technology
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• v.56 no.1
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• pp.195-206
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• 2024

Shenzhen Innovation Light source Facility (SILF) is a 3.0 GeV fourth generation diffraction limited synchrotron light source currently under construction in Shenzhen. The SILF storage ring is proposed to use two 500 MHz single cell superconducting radio frequency (SRF) cavities to provide 2.4 MV RF voltage. In this study, we examined the geometric structure of mature CESR superconducting cavities and adopted a beam-pipe-type extraction scheme for high-order modes (HOM). One of the objectives of SRF cavity design and optimization in this study is to reduce E_p/E_acc and B_p/E_acc as much as possible to reduce power loss and ensure stable operation of the cavity. To reduce the risk of beam instability and thermal breakdown, the HOM and Multipacting (MP) are simulated. Moreover, the mechanical properties of the cavity are analyzed, including frequency sensitivity from pressure of liquid helium (LHe), stress, tuning, Lorentz force detuning (LFD), the microphone effect, and buckling. By comprehensive design and optimization of 500 MHz single-cell SRF cavities, a superconducting cavity for SILF storage ring was developed. This paper will detailed present the design and simulation.

• Korean Journal of Veterinary Service
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• v.47 no.1
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• pp.19-26
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• 2024

Canine atopic dermatitis (CAD) is an inflammatory and pruritic skin disease with a genetic predisposition, characterized by allergic sensitivity. It is known for its distinctive clinical features, including a high recurrence rate and chronic progression. To manage CAD, medications such as steroids and immunosuppressants are commonly used, but consideration should be given to the potential resistance and side effects associated with long-term use. In order to reduce these risks, various adjunctive factors are currently under consideration. One of these adjunctive agents, probiotics have shown effectiveness in regulating atopic dermatitis by modulating immune responses, as demonstrated in several recent studies. In this study, a substance combining three probiotics-L. plantarum, L. reuteri, and Ped. Acidilactici-was used in patients diagnosed with CAD, and its clinical effects and safety were evaluated. The trial involved four groups: a group receiving conventional treatment for atopic dermatitis (A), a group prescribed low-dose probiotics (B), a group prescribed high-dose probiotics (C), and a group prescribed topical probiotics (D). For assessment, the Canine Atopic Dermatitis Extent and Severity Index (CADESI), Trans-Epidermal Water Loss (TEWL) test, gut microbiome, and serum IgE test were conducted. As a result, the CAD severity index (CADESI-4) significantly decreased in the probiotics groups (B & C). In the serum total IgE test, the groups consuming probiotics showed a significant difference, while the group using topical probiotics (D) did not exhibit a significant change. Also, the TEWL test showed improved scores in the probiotics groups (B & C). Therefore, L. plantarum, L. reuteri, and Ped. Acidilactici probiotic combination could be considered as an effective adjunctive treatment, especially for atopic patients with moderate to severe skin lesions.

• Journal of the Korean Institute of Gas
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• v.28 no.2
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• pp.47-55
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• 2024

More than 100 liquefied hydrogen tanks are expected to be introduced in Korea by 2030. Since liquefied hydrogen is stored in a vacuum insulation structure tank at -253℃, there is a possibility of a major disaster in which the tank bursts if there is a problem with insulation. Therefore, the law stipulates that PRV should be installed as the last bastion. It is important to note that in the case of liquefied hydrogen, it becomes useless if the pressure drop of the pipe is ignored and the capacity is calculated incorrectly. In CGA S-1.3, the pressure drop rate of the PRV inlet and outlet pipes is set to less than 3% and less than 10%, respectively. However, there is an interdependence between the amount of pressure drop and the flow rate of the pipe, making it impossible to calculate these values at once. Therefore, we developed a simulator that calculates the pressure loss rate of PRV system using MATLAB/Simulink and evaluated the sensitivity of the pressure drop rate to design elements.

• The Journal of the Acoustical Society of Korea
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• v.20 no.2E
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• pp.30-45
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• 2001

This study considers the environmental factors affecting propagation loss and sonar performance in the continental regions of the East Coast Sea of Korea. Water mass distributions appear to change dramatically in a few weeks. Simple calculation with the case when the NKCW (North Korean Cold Water) develops shows that the difference in propagation loss may reach in the worst up to 10dB over range 5km. Another factor, an eddy, has typical dimensions of 100-200km in diameter and 150-200m in thickness. Employing a typical eddy and assuming frequency to be 100Hz, its effects on propagation loss appear to make lower the normal formation of convergence zones with which sonars are possible to detect long-range targets. The change of convergence zones may result in 10dB difference in received signals in a given depth. Thermal fronts also appear to be critical restrictions to operating sonars in shallow waters. Assuming frequency to be 200Hz, thermal fronts can make 10dB difference in propagation loss between with and without them over range 20km. An observation made in one site in the East Coast Sea of Korea reveals that internal waves may appear in near-inertial period and their spectra may exist in periods 2-17min. A simulation employing simple internal wave packets gives that they break convergence zones on the bottom, causing the performance degradation of FOM as much as 4dB in frequency 1kHz. An acoustic experiment, using fixed source and receiver at the same site, shows that the received signals fluctuate tremendously with time reaching up to 6.5dB in frequencies 1kHz or less. Ambient noises give negative effects directly on sonar performance. Measurements at some sites in the East Coast Sea of Korea suggest that the noise levels greatly fluctuate with time, for example noon and early morning, mainly due to ship traffics. The average difference in a day may reach 10dB in frequency 200Hz. Another experiment using an array of hydrophones gives that the spectrum levels of ambient noises are highly directional, their difference being as large as 10dB with vertical or horizontal angles. This fact strongly implies that we should obtain in-situ information of noise levels to estimate reasonable sonar performance. As one of non-stationary noise sources, an eel may give serious problems to sonar operation on or under the sea bottoms. Observed eel noises in a pier of water depth 14m appear to have duration time of about 0.4 seconds and frequency ranges of 0.2-2.8kHz. The 'song'of an eel increases ambient noise levels to average 2.16dB in the frequencies concerned, being large enough to degrade detection performance of the sonars on or below sediments. An experiment using hydrophones in water and sediment gives that sensitivity drops of 3-4dB are expected for the hydrophones laid in sediment at frequencies of 0.5-1.5kHz. The SNR difference between in water and in sediment, however, shows large fluctuations rather than stable patterns with the source-receiver ranges.

• Journal of the korean academy of Pediatric Dentistry
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• v.43 no.4
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• pp.452-460
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• 2016

Burkitt lymphoma (BL) is an aggressive form of non-Hodgkin's B-cell lymphoma found primarily in the pediatric population. In the oral cavity, this tumor can grow rapidly and often brings about facial swelling or development of an exophytic mass involving the jaws. A 5-year-old boy was referred for swelling and pain in the left mandibular area. The patient showed diffuse swelling on the left side of the mandible and firm-moderate tenderness upon palpation. An intraoral examination showed moderate mobility and sensitivity to percussion on the left primary first and second molars, without severe caries. A radiographic examination revealed complete loss of the lamina dura on the left primary second molar and permanent first molar. There was a radiolucent osteolytic lesion and destruction of the cortical bone of the left mandibular body. Based on the clinical, radiographic, and immunohistochemical findings, the patient was diagnosed with BL, and was referred to a pediatrician for systemic evaluation and intensive chemotherapy. Even before the completion of chemotherapy, the swelling resolved and the displaced teeth were relocated to a normal position. This patient showed a good prognosis due to prompt diagnosis and intensive chemotherapy. Early diagnosis and referral for treatment can prevent the development of BL.

• Journal of Korean Society of Steel Construction
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• v.17 no.2 s.75
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• pp.115-130
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• 2005

This paper presents the effects of indirect costs on Life-Cycle-Cost(LCC) effective optimum design of steel-box girder bridges. The LCC formulations considered in the LCC optimization of the bridges consist of initial cost and expected rehabilitation costs including repair/replacement costs, loss of contents or fatality and injury losses, and indirect costs such as road user costs and indirect socio-economic losses. To demonstrate the LCC-effectiveness for optimum design of the bridges, an actual steel box girder bridge having two continuous spans(2@50m=100m) is considered as a numerical example. And also, in this paper, various sensitivity analyses are performed to investigate the effects of indirect costs caused by traffic conditions such as number of detour route, number of lane on detour route, length of detour route, and traffic volumes on the LCC-effective optimum design. From the numerical investigations, it may be concluded that indirect costs caused by traffic network may sensitively influence on the LCC-effective optimum design of steel-box girder bridges. Therefore, it may be stated that the traffic conditions should be considered as one of the important items in the LCC-effective optimum design of the bridges.

• Journal of Korean Society of Steel Construction
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• v.17 no.2 s.75
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• pp.227-241
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• 2005

This paper presents a practical and realistic Life-Cycle Cost (LCC) optimum design methodology for steel bridges considering the long-term effect of environmental stressors such as corrosion and heavy truck traffics on bridge reliability. The LCC functions considered in the LCC optimization consist of initial cost, expected life-cycle maintenance cost, and expected life-cycle rehabilitation costs including repair/replacement costs, loss of contents or fatality and injury losses, road user costs, and indirect socio-economic losses. For the assessment of the life-cycle rehabilitation costs, the annual probability of failure, which depends upon the prior and updated load and resistance histories, should be accounted for. For the purpose, Nowak live load model and a modified corrosion propagation model, which takes into consideration corrosion initiation, corrosion rate, and repainting effect, are adopted in this study. The proposed methodology is applied to the LCC optimum design problem of an actual steel box girder bridge with 3 continuous spans (40m+50m+40m=130m). Various sensitivity analyses are performed to investigate the effects of various design parameters and conditions on the LCC-effectiveness. From the numerical investigation, it has been observed that local corrosion environments and the volume of truck traffic significantly influence the LCC-effective optimum design of steel bridges. Thus, these conditions should be considered as crucial parameters for the optimum LCC-effective design.

• Horticultural Science & Technology
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• v.30 no.6
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• pp.718-724
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• 2012

Sugars play important roles in petal senescence of cut flowers. In the Expt. 1 of this study, the effects of different concentrations of glucose (60, 90, and $120g{\cdot}L^{-1}$) and sucrose (30, 60, and $90g{\cdot}L^{-1}$) application on the vase life, rate of flower diameter increase, rate of flower weight increase and ethylene production of cut tree peony (Paeonia suffruticosa 'Luoyang Hong') were evaluated. At the earlier stage, treatments of different concentrations of glucose and sucrose all retarded the process of flower opening and inhibited the increase of flower diameter and weight, while senescence of flowers fed with different concentrations of glucose was delayed at later stage. Flowers treated with $90g{\cdot}L^{-1}$ glucose displayed the longest vase life, which showed significant difference (P < 0.05) from those of flowers with the control and sucrose treatments. All treatments with glucose or sucrose not only retarded the decrease of flower diameter and weight, but also suppressed the ethylene production at the earlier stage and delayed the peak of ethylene evolution. In order to study the effect of exogenous sugar on the postharvest response of cut tree peony to ethylene, Expt. 2 was conducted. Cut flowers were treated with $90g{\cdot}L^{-1}$ glucose for 4 hours before (GE) or after (EG) exposed to $10{\mu}L{\cdot}L^{-1}$ ethylene for 4 hours. Generally, the opening process of flowers with GE and EG treatments was similar to that of the control, however GE treatment delayed flower senescence. Both GE and EG treatments improved flower diameter and weight, and GE treatment delayed the time of flower weight decrease. Besides, GE delayed climacteric ethylene evolution for 8 hours. All above suggest that exogenous sugars delay tree peony 'Luoyang Hong' cut flower senescence and extend flower vase life through their roles in the decrease of water loss and the suppression of sensitivity to ethylene and ethylene production.

• Journal of Microbiology and Biotechnology
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• v.27 no.3
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• pp.633-643
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• 2017

To examine the pro-apoptotic role of the human ortholog (YPEL5) of the Drosophila Yippee protein, the cell viability of Saccharomyces cerevisiae mutant strain with deleted MOH1, the yeast ortholog, was compared with that of the wild-type (WT)-MOH1 strain after exposure to different apoptogenic stimulants, including UV irradiation, methyl methanesulfonate (MMS), camptothecin (CPT), heat shock, and hyperosmotic shock. The $moh1{\Delta}$ mutant exhibited enhanced cell viability compared with the WT-MOH1 strain when treated with lethal UV irradiation, 1.8 mM MMS, $100{\mu}M$ CPT, heat shock at $50^{\circ}C$, or 1.2 M KCl. At the same time, the level of Moh1 protein was commonly up-regulated in the WT-MOH1 strain as was that of Ynk1 protein, which is known as a marker for DNA damage. Although the enhanced UV resistance of the $moh1{\Delta}$ mutant largely disappeared following transformation with the yeast MOH1 gene or one of the human YPEL1-YPEL5 genes, the transformant bearing pYES2-YPEL5 was more sensitive to lethal UV irradiation and its UV sensitivity was similar to that of the WT-MOH1 strain. Under these conditions, the UV irradiation-induced apoptotic events, such as FITC-Annexin V stainability, mitochondrial membrane potential (${\Delta}{\psi}m$) loss, and metacaspase activation, occurred to a much lesser extent in the $moh1{\Delta}$ mutant compared with the WT-MOH1 strain and the mutant strain bearing pYES2-MOH1 or pYES2-YPEL5. These results demonstrate the functional conservation between yeast Moh1 and human YPEL5, and their involvement in mitochondria-dependent apoptosis induced by DNA damage.

• Magazine of the Korean Society of Agricultural Engineers
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• v.28 no.3
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• pp.79-88
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• 1986

Drought occurs most frequently and severely around transplanting season of the rice plants in Korea. Shortage of water due to drought for the paddy fields often delays transplanting, and less often the rice plants are subjected to water stress after delayed transplanting. The present study aimed at quantification of the rice crop loss due to delayed transplanting, different inten3ity of water stress, and the combined effect of delay in transplanting followed by water stress for better use of limited water for irrigation under drought. The rice variety Chucheong, a japonica, and Nampung, an indica x japonica, were grown, transplanted to 1/200 a plastic pots, and subjected to different timing of transplanting and degree of water stress under a rainfall autosersing, sliding clear plastic roof facility with completely randomized arrangement of 5 replications. The results obtained are summarized as follows: 1.Twelve days or 22 days delay in transplanting without water stress reduced rice yield by 25% and 43% in the japonica variety, and by 15% and 60% in the indica x japonica variety. 2.The 10 days or 20 days water stress developed without irrigation after drainage in the rice plants transplanted at proper time lowered the water potential at the paddy soil 10cm deep to -4 bar, and -12 bar and caused rice yield reduction by 14%, and 45% in the japonica variety and by 8%, and 50% in the indica X japonica variety. 3.The 12 days delay in transplanting and 10 days or 20 days water stress reduced rice yield by 39% and 59% in the japonica variety, and by 38% and 52% in the indica x japonica variety. The 22 days delay in transplanting plus 10 days water stress caused yield reduction by 76%, i.e. meaningless yield, in both varieties. 4.The intermittent irrigation just to wet the soil body for 10 days after 10 days water stress without irrigation increased rece yield by 12 to 16% compared to the rice plants water stessed without irrigation continuously for 20 days in both varieties respectively. 5.The above results suggest strongly 1) to transplant the rice plants at proper .time even with some water stress rather than delay for sufficient water from later rainfall, and 2) to distribute insufficient irrigation water to broader area of transplanted rice with limited irrigation for better use of limited irrigation water. A greater sensitivity of japonica variety to a moderate water stress than the indica X japonica variety during initial rooting and tillering stage was noticed. To cope with frequent drought in rice culture, firstly the lasting time of transplanting without yield reduction should be clarified by region and variety, and secondly a scheme of rational distribution of limited water should be developed by region with better knowledge on the varietal distribution of limited water should be developed by region with better knowledge on the varietal responses to varying intensity of water stress.