• Title/Summary/Keyword: Loss and damage

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A Case of Granulomatosis with Polyangiitis with IgG4-Related Disease Expressed by Facial Paralysis and Hearing Loss (안면 마비와 난청으로 진단된 면역글로불린 G4 연관질환 동반 육아종성 다발 혈관염 1예)

  • Kim, Hyung-sik;Doo, Jeon Gang;Yeo, Seung Geun;Kim, Sang Hoon
    • Journal of Clinical Otolaryngology Head and Neck Surgery
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    • v.29 no.2
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    • pp.240-244
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    • 2018
  • Granulomatosis with polyangiitis (GPA) and Immunoglobulin (Ig) $G_4$-related disease ($IgG_4$-RD) are rare diseases and early diagnosis and proper management are imperative to prevent multi-organ damage. The authors present a case of a 60 years old woman who had facial paralysis and hearing loss. Lt intact canal wall tympanomastoidectomy, Lt facial nerve decompression and ossiculoplasty with partial ossicular replacement prosthesis (PORP) was done. During operation, middle ear tissue was biopsied and GPA with $IgG_4$-RD was diagnosed. After methyl prednisolone (MPD) pulse therapy and azathioprine therapy, the severity of paralysis was improved. We present this case because common otologic symptoms like facial palsy and hearing loss could be initial symptoms of rare systemic disease.

The Change of the Physical Properties of Rayon/Cotton Blend Fabrics Treated with Cellulase by Addition of Silicon (셀룰라아제 처리시 실리콘 첨가에 따른 레이온/면 혼방직물의 물성변화)

  • 이선화;송화순
    • Journal of the Korean Society of Clothing and Textiles
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    • v.22 no.8
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    • pp.1032-1042
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    • 1998
  • The purpose of this study is to measure, compare, and investigate the physical properties of rayon/cotton blend fabrics treated with cellulase and cellulase & specific degeneration silicon and to present basic data which is in development a value-added fabric. The results are as follows. The condition for the treatment of cellulase was at 55$^{\circ}C$, pH 4 and the weight loss increased as the concentration of cellulase and the treated time increased. On treatment with cellulase, the crossectional view & longitudinal view of fiber noticed remarkable crack as weight loss increased and tensile strength and elongation decreased, and pilling was enhanced remarkably. KOSHI was increased, NUMERI and FUKURAMI were decreased as weight loss increased. In the basic characteristic value of clothing wearning, shape stability and drapability were decreased, but air content was improved. On treatment with cellulase & silicon, the degree of damage in the crossectional view & longitudinal view of the fiber reduced. Tensile strength, elongation, moisture regain improved. KOSHI and FUKURAMI were reduced, NUMERI was improved rather than when it was treated with cellulase. Therefore handle was improved. In the basic characteristic value of the clothing wearing, shape stability, air content, drapability were improved.

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An Efficient Design of a DC-Block Band Pass Filter for the L-Band

  • Kaur, Avneet;Malhotra, Jyoteesh
    • Transactions on Electrical and Electronic Materials
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    • v.18 no.2
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    • pp.62-65
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    • 2017
  • In this paper, three DC Block designs are presented which efficiently meet the need of modern-day compactsize wireless communication systems. As one of the important parts of a complete system design, the proposed microstrip-based DC block with coupled transmission lines efficiently attenuates unwanted frequencies that cause damage to the system. The compact-sized DC block structures are created by incorporating an extended coupled-line section with a radial stub, an enveloped coupled-line section, and using alternate up-down meandering techniques. The structures are analyzed for the L-Band using a high-resistive silicon substrate. At a resonating frequency of 1.575 GHz, the designed DC Block structures have a return loss better than -10 dB, an insertion loss of around -1 dB, and also possess wide pass-band characteristics.

A study on the Erosion Characteristics of Transducer Horn Disc in Sludge Oil Environment (슬러지유 환경에서 진동자 디스크의 침식 특성에 관한 연구)

  • 정지선;한원희;하만식;이진열
    • Proceedings of the Korean Society of Marine Engineers Conference
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    • 2001.11a
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    • pp.98-104
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    • 2001
  • Recently, the researches on the prevention of marine oil pollution being strengthened. Sludge oils were unavoidably produced in ship's operations, therefore it is necessary to manage the sludge oils inside the ship itself with the view to prevent marine oil pollution from ship. The present study deals with the ultrasonic breaking systems that recycle the sludge oil from ships into usable oil to be burnt. At the first instanceexperimental studies were carried out to investigate the homogenizing effect of the marine oils and the erosion aspect of horn disc by repeated vibration of ultrasonic transducer. The erosion damages for horn disc SS41 steel with weight loss rate and the irradiation time to max. erosion rate were examined according to the variation of the transducer amplitude, the oil temperature and the immersing depth of horn disc. As the result of it, the erosion aspects of horn disk were varied with oil environments and testing time.

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Corrosion Characteristics of Cast Stainless Steel under Plasma Ion Nitriding Process Temperature in Marine Environment (주조 스테인리스강의 해양환경 하에서 플라즈마 이온질화 공정온도에 따른 부식특성 연구)

  • Chong, Sang-Ok;Kim, Seong-Jong
    • Journal of Surface Science and Engineering
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    • v.50 no.6
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    • pp.504-509
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    • 2017
  • In order to improve corrosion resistance for cast stainless steel in seawater, the characteristics of corrosion resistance after plasma ion nitriding was investigated. Plasma ion nitriding process was conducted in a mixture of nitrogen of 25% and hydrogen of 75% at substrate temperature ranging from 350 to $500^{\circ}C$ for 10 hours using pulsed-DC glow discharge plasma with working pressure of 250 Pa in vacuum condition. Corrosion tests were carried out for as-received and plasma ion nitrided specimens. The corrosion characteristics were investigated by measurement of weight loss and observation of surface morphology. In anodic polarization experiment, relatively less damage depth and weight loss were presented at a nitrided temperature of $400^{\circ}C$, attributing to the formation of S-phase.

Effect of Weight Loss and Improvement of Liver Function through Korean Medicinal Treatment: Case Report (한약치료의 체중 감량 효과와 간기능 개선: 증례보고)

  • Sejin Kim;Changhyun Ko
    • Journal of Korean Medicine for Obesity Research
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    • v.22 no.2
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    • pp.167-172
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    • 2022
  • Obesity is known as the most common risk factor for non-alcoholic fatty liver disease. Weight loss is needed to prevent liver function damage from progressing to non-alcoholic hepatosteatosis (NASH) and NASH-related liver cirrhosis. The purpose of this study was to observe the recovery of liver function in obese patients with liver dysfunction through traditional Korean obesity treatment. Body weight, liver function levels and renal function levels were examined by prescribing traditional Korean medicine in obese patients with mild elevation of liver function test. Blood tests were conducted at intervals of one month, and it was observed that liver function recovered to the normal range in three patients.

Loss of strength in asbestos-cement water pipes due to leaching

  • Gil, Lluis;Perez, Marco A.;Bernat, Ernest;Cruz, Juan J.
    • Structural Engineering and Mechanics
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    • v.40 no.5
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    • pp.655-663
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    • 2011
  • Asbestos-cement is a material with valuable strength and durability. It was extensively used for water distribution pipes across the world from the 1950s until the early 1980s. The network of pipes in this case study dates from the 1970s, and after more than 30 to 40 years of service, some pipes have been found to break under common service pressure with no apparent reason. A set of mechanical tests was performed including bending, compression, pressure and crushing tests. Microscopy analysis was also used to understand the material behaviour. Tests showed that there was a clear loss of strength in the pipes and that the safety factor was under the established threshold in most of the specimens. Microscopy results showed morphological damage to the pipes. The loss of strength was attributed to a leaching effect. Leaching damages the cement matrix and reduces the frictional interfacial shear stress.

Effects of electronic energy deposition on pre-existing defects in 6H-SiC

  • Liao, Wenlong;He, Huan;Li, Yang;Liu, Wenbo;Zang, Hang;Wei, Jianan;He, Chaohui
    • Nuclear Engineering and Technology
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    • v.53 no.7
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    • pp.2357-2363
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    • 2021
  • Silicon carbide is widely used in radiation environments due to its excellent properties. However, when exposed to the strong radiation environment constantly, plenty of defects are generated, thus causing the material performance downgrades or failures. In this paper, the two-temperature model (2T-MD) is used to explore the defect recovery process by applying the electronic energy loss (Se) on the pre-damaged system. The effects of defect concentration and the applied electronic energy loss on the defect recovery process are investigated, respectively. The results demonstrate that almost no defect recovery takes place until the defect density in the damage region or the local defect density is large enough, and the probability of defect recovery increases with the defect concentration. Additionally, the results indicate that the defect recovery induced by swift heavy ions is mainly connected with the homogeneous recombination of the carbon defects, while the probability of heterogeneous recombination is mainly dependent on the silicon defects.

Analysis of pile group behaviour to adjacent tunnelling considering ground reinforcement conditions with assessment of stability of superstructures

  • Young-Jin Jeon;Cheol-Ju Lee
    • Geomechanics and Engineering
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    • v.33 no.5
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    • pp.463-475
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    • 2023
  • Tunnel construction activity, conducted mainly in mountains and within urban centres, causes soil settlement, thus requiring the relevant management of slopes and structures as well as evaluations of risk and stability. Accordingly, in this study we performed a three-dimensional finite element analysis to examine the behaviour of piles and pile cap stability when a tunnel passes near the bottom of the foundation of a pile group connected by a pile cap. We examined the results via numerical analysis considering different conditions for reinforcement of the ground between the tunnel and the pile foundation. The numerical analysis assessed the angular distortion of the pile cap, pile settlement, axial force, shear stress, relative displacement, and volume loss due to tunnel excavation, and pile cap stability was evaluated based on Son and Cording's evaluation criterion for damage to adjacent structures. The pile located closest to the tunnel under the condition of no ground reinforcement exhibited pile head settlement approximately 70% greater than that of the pile located farthest from the tunnel under the condition of greatest ground reinforcement. Additionally, pile head settlement was greatest when the largest volume loss occurred, being approximately 18% greater than pile head settlement under the condition having the smallest volume loss. This paper closely examines the main factors influencing the behaviour of a pile group connected by a pile cap for three ground reinforcement conditions and presents an evaluation of pile cap stability.

Glycogen Phosphorylase Inhibitor Promotes Hair Growth via Protecting from Oxidative-Stress and Regulating Glycogen Breakdown in Human Hair follicles

  • Bomi Park;Daeun Kim;Hairu Zhao;SoonRe Kim;Byung Cheol Park;Sanghwa Lee;Yurim Lee;Hee Dong Park;Dongchul Lim;Sunyoung Ryu;Jae Sung Hwang
    • Biomolecules & Therapeutics
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    • v.32 no.5
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    • pp.640-646
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    • 2024
  • Hair growth cycles are mainly regulated by human dermal papilla cells (hDPCs) and human outer root sheath cells (hORSCs). Protecting hDPCs from excessive oxidative stress and hORSCs from glycogen phosphorylase (PYGL) is crucial to maintaining the hair growth phase, anagen. In this study, we developed a new PYGL inhibitor, hydroxytrimethylpyridinyl methylindolecarboxamide (HTPI) and assessed its potential to prevent hair loss. HTPI reduced oxidative damage, preventing cell death and restored decreased level of anagen marker ALP and its related genes induced by hydrogen peroxide in hDPCs. Moreover, HTPI inhibited glycogen degradation and induced cell survival under glucose starvation in hORSCs. In ex-vivo culture, HTPI significantly enhanced hair growth compared to the control with minoxidil showing comparable results. Overall, these findings suggest that HTPI has significant potential as a therapeutic agent for the prevention and treatment of hair loss.