• Archives of Pharmacal Research
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• v.10 no.2
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• pp.80-87
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• 1987

To get a better insight into the exxistence and the role of a Na-Ca exchange mechanism in smooth muscle, the effect of Na substitution with sucrose on tension development, cellular Ca uptake and $^{45}Ca$ efflux was investigated using isolated cat ileal longitudinal muscle strips. Experimental results were summarized as follows;1) Exposure of the cat ileal longitudinal muscle to Na-free solution induced a contraction, and the magnitude of the contraction increased after incubation of the muscle strips with ouabain ($2{\times10^{-}5}$M) for 1hr. 2) Cellular Ca uptake in Na-free solution increased with an increase in Na content of the Na-loading media, and a linear relationship existed between tissue Na content and cellular Ca uptake for 10 min 3) After tissues were equilibrated in PSS containing $^{45}Ca$ for 2hr, cellular Ca uptake decreased with rising the external Na concentration. 4)Removal of medium Na or inhibition of the Na-K pump decreased the rate of $^{45}Ca$ efflux. These results strongly suggested that Na substitution increases cellular Ca uptake and decreases the rate of $^{45}Ca$ efflux via a Na-Ca exchange mechanism.

• Advances in materials Research
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• v.12 no.1
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• pp.15-29
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• 2023

In this paper, fracture analysis of a continuously inhomogeneous arch structure with two longitudinal cracks is developed in terms of the time-dependent strain energy release rate. The arch under consideration exhibits non-linear creep behavior. The cross-section of the arch is a rectangle. The material is continuously inhomogeneous along the thickness of the cross-section. The arch is loaded by two bending moments applied at its end sections. The mechanical behavior of the material is described by using a non-linear stress-strain-time relationship. The two longitudinal cracks are located symmetrically with respect to the mid-span of the arch. Due to the symmetry, only half of the arch is considered. Time-dependent solutions to strain energy release rate are obtained by analyzing the balance of the energy. For verification, time-dependent solutions to the strain energy release rate are derived also by considering the time-dependent complementary strain energy. The evolution of the strain energy release rate with the time is analyzed. The effects of material inhomogeneity, locations of the two cracks along the thickness of the arch and the magnitude of the external loading on the time-dependent strain energy release rate are evaluated.

• Journal of the Korean Society for Nondestructive Testing
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• v.19 no.4
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• pp.259-269
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• 1999

Elastic wave velocity measurement technique such as impact-echo method and ultrasonic pulse velocity method has been successfully used to evaluate the moduli and strength of concrete. However, estimation results obtained by the NDT methods do not agree well with real things because longitudinal wave velocity is influenced by various factors. In this paper, among several factors influencing P-wave velocity, the influence of moisture content in concrete was investigated through the experiment. Test results show that longitudinal wave velocity is significantly affected by the moisture content of concrete, i.e., the lower moisture content. the lower velocity. Moisture content influences rod-wave velocity measured by impact-echo method stronger than ultrasonic pulse velocity measured by transmission method. During drying process with ages. the difference of increasing rate between longitudinal wave velocity and compressive strength of concrete is gradually increased. Therefore, to establish more accurate relationship between longitudinal wave velocity and strength, the difference of the increasing rate should be considered.

• The Korean Journal of Applied Statistics
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• v.29 no.1
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• pp.113-122
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• 2016

Longitudinal data often occur in prospective follow-up studies. Joint model for longitudinal data and failure time has been applied on several works. In this paper, we extend it to the case where longitudinal data involve informative observation time process as well as competing risks survival times. We use a likelihood approach and derive an EM algorithm to obtain maximum likelihood estimate of parameters. A suggested joint model allows us to make inferences for three components: longitudinal outcome, observation time process and competing risk failure time. In addition, we can test the association among these components. In this paper, liver cirrhosis patients' data is analyzed. The relationship between prothrombin times measured at irregular visiting times and drop outs is investigated with a joint model.

• Korean Journal of Social Welfare Studies
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• v.42 no.3
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• pp.183-206
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• 2011

This study examined the longitudinal relationship between academic achievement and school satisfaction using a data of the Seoul Panel Study of Children(SPSC). Fully autoregressive cross-lagged analysis and multi-group comparison were performed to measure the longitudinal relationship between two constructs as well as differences between poverty and non-poverty groups. The results showed that both academic achievement and school satisfaction were stable over time in non-poverty group. Academic achievement at the 4th grade significantly affected the school satisfaction at the 6th grade and it subsequently affected on the academic achievement at the 8th grade in non-poverty group. In contrast, academic achievement was not consistent over time in poverty group. Only the school satisfaction at the 6th grade affected the academic achievement at the 8th grade. The findings of this study have various practical implication for school interventions. It is more important to keep supporting the children to maintain the level of academic achievement in non-poverty group. While, in poverty group, it is essential to make school satisfaction and academic motivation increase with school attachment programs.

• Management & Information Systems Review
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• v.38 no.1
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• pp.121-139
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• 2019

This study aims to identify the change of customer participation(CP) which is essential to the service industry as the relationship between the customer and the employee develops. The latent growth modeling analysis based on the longitudinal data is utilized to examine the pattern of the change. This is based on the fact that CP needs to be understood in the relationship and is to confirm the change in CP by the development of the relationship. Given the dynamics of the relationship, we intend to overcome the limitations of previous cross-sectional researches by revealing the trajectory of CP in the relationship through the longitudinal data. We also want to examine which variables in the relationship can facilitate changes of CP. Research has shown that CP is significantly changed with the development of the relationship when we analyzed it through latent growth modeling. This confirms that CP needs to be understood in the relationship. In addition, 'relationship proneness' variable and 'dependence to provider' variable have positive effects on the initial values of CP, but they have not been established to promote the changes of CP. Consequently, when considering the dynamics of relationships, it is important to recognize that CP is also dynamic. This study sought to get out of the cross-sectional and fragmented understanding of CP that is dynamic. Through this, we would like to propose the successful operation of the customer management program of service firms in relation to CP. This will lead to the success of service encounter where appropriate CP levels at each stage of relationship development can be achieved.

• Journal of Korean Society on Water Environment
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• v.28 no.4
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• pp.512-522
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• 2012

This study is focused on fish fauna and distributional features along with physical gradients and stream orders in the Tamjin River basin, Korea. Fish sampling and investigation were conducted for 2 years from 2009 to 2010. Total number of fish species collected were 47 species of 16 family. The group of cyprinidae was mostly abundant. Both fish abundance and biotic index were declined with increasing altitude and longitudinal distance from the river mouth. Two species of Zacco temminckii and Pungtungia herzi were prevalent in most of sampling sites and showed no altitudinal and longitudinal differences. Most other species, however, were spatially restricted to specific regional altitudes. Several species including Zacco platypus, Squalidus gracilis majimae and P. herzi were broadly distributed from river mouth to 50 km. Eight species including Z. temminckii and Rhynchocypris oxycephalus only appeared in over 10 km from the river mouth. Both Odontobutis platycephala and Pseudobagrus koreanus were classified as "upstream dewelling species" observed only in over 30 km from the river mouth. High proportion of tolerant and omnivorous species were more dominated in the downstream zone of the dam, whereas intolerant and insectivorous species were abundant in the upstream zone of the dam. The variable of stream order showed positive relationship between number of fish species and total individuals collected. Sensitive species including insectivore had a declining tendency with increasing stream order, while tolerant specie including omnivore species had relatively increased with stream order. Overall, our study suggested that fish distribution considerably depends on altitudinal gradient and longitudinal distance from the river mouth as well as physical habitat.

• Journal of Korean Neurosurgical Society
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• v.58 no.5
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• pp.442-447
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• 2015

Objective : Ossification of the ligamentum nuchae (OLN) is usually asymptomatic and incidentally observed in cervical lateral radiographs. Previous literatures reported the correlation between OLN and cervical spondylosis. The purpose of this study was to elucidate the clinical significance of OLN with relation to cervical ossification of posterior longitudinal ligament (OPLL). Methods : We retrospectively compared the prevalence of OPLL in 105 patients with OLN and without OLN and compared the prevalence of OLN in 105 patients with OPLL and without OPLL. We also analyzed the relationship between the morphology of OLN and involved OPLL level. The OPLL level was classified as short (1-3) or long (4-6), and the morphologic subtype of OLN was categorized as round, rod, or segmented. Results : The prevalence of OPLL was significantly higher in the patients with OLN (64.7%) than without OLN (16.1%) (p=0.0001). And the prevalence of OLN was also higher in the patients with OPLL (54.2%) than without OPLL (29.5%) (p=0.0002). In patients with round type OLN, 5 of 26 (19.2%) showed long level OPLL, while in patients with larger type (rod and segmented) OLN, 22 of 42 (52.3%) showed long level OPLL (p=0.01). Conclusion : There was significant relationship between OLN and OPLL prevalence. This correlation indicates that there might be common systemic causes as well as mechanical causes in the formation of OPLL and OLN. The incidentally detected OLN in cervical lateral radiograph, especially larger type, might be helpful to predict the possibility of cervical OPLL.

• Journal of Korean Neurosurgical Society
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• v.49 no.1
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• pp.8-12
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• 2011

Objective: Ossification of the posterior longitudinal ligament (OPLL) has a strong genetic component. Specific gene polymorphisms may be associated with OPLL in several genes which regulate calcification in chondrocytes, change of extracellular collagen matrix and secretions of many growth factors and cytokines controlling bone morphogenesis. Toll-like receptor 5 (TLR5) may playa role in the pathogenesis of OPLL by intermediate nuclear factor-kappa B (NF-${\kappa}B$). The current study focused on coding single nucleotide polymorphisms (SNPs) of TLR5 for a case-control study investigating the relationship between TLR5 and OPLL in a Korean population. Methods: A total of 166 patients with OPLL and 231 controls were recruited for a case-control association study investigating the relationship between SNPs of TLR5 gene and OPLL. Four SNPs were genotyped by direct sequencing (rs5744168, rs5744169, rs2072493, and rs5744174). SNP data were analyzed using the SNPStats, SNPAnalyzer, Haploview, and Helixtree programs. Multiple logistic regression analysis with adjustment for age and gender was performed to calculate an odds ratio (OR). Results: None of SNPs were associated with OPLL in three alternative models (codominant, dominant, and recessive models; p> 0.05). A strong linkage disequilibrium block, including all 4 SNPs, was constructed using the Gabriel method. No haplotype was significantly associated with OPLL in three alternative models. Conclusion: These results suggest that Toll-like receptor 5 gene may not be associated with ossification of the posterior longitudinal ligament risk in Korean population.

• Journal of vocational education research
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• v.35 no.4
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• pp.89-107
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• 2016

The purpose of this study was to verify the causal relationship between self-directed learning ability and career maturity by Middle and High School Students in Seoul. This study used Seoul Education Longitudinal Study(SELS) data. Using autoregressive cross-lagged modeling, the results was followed. first, self-directed learning ability value was had a statistically significant positive effect in accordance with the time course from middle school 1st grade to high school 3rd grade. Second, career maturity also had a statistically significant positive effect in accordance with the time course from middle school 1st grade to high school 3rd grade. Third, previous self-directed learning ability had significant positive effect on the later career maturity, but the previous career maturity had no significant effect on later self-directed learning ability.