• Journal of the Korean Ceramic Society
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• 제45권6호
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• pp.309-319
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• 2008

This study evaluates a range of materials that may be used to design prostheses for bone. It is found that nanocrystalline ceramic-polymer composite could be the best material for prosthetic bone with respect to biocompatibility, morphology, chemistry, and compatibility with the piezoelectric and mechanical behavior of long human bones, such as the femur.

• Journal of Korean Foot and Ankle Society
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• 제27권4호
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• pp.154-157
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• 2023

Chondroblastoma is a rare benign cartilaginous neoplasm that accounts for 1% of bone tumors and is common in the epiphysis of the long bones. The condition is rarely found in the talus bone (4% of cases). This paper reports a 15-year-old male patient treated for a talus bone lesion discovered incidentally on imaging. Excisional biopsy, curettage, and an autobone and allobone graft were performed, with good results.

• Journal of Periodontal and Implant Science
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• 제34권3호
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• pp.551-562
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• 2004

The purpose of this study was to evaluate the effects of negatively electric field on bone healing in rabbit segmental long bone defects using negatively charged PTFE membrane. Ten millimeter segmental defects in the rabbit radius were used as the experimental model. After membranes were then charge injected using a corona-charging apparatus, the left defects were covered with non charged PTFE membranes as control groups, whereas the right defect was covered with negatively charged PTFE membranes as test group. The animals were divided into 4 groups of 2 rabbits each, and sacrificed at 2, 4, 6, and 8 weeks. Histomorphometric analysis showed a more newly formed bone in negatively charged membrane at early healing period. At 2 weeks, the proportion of new bone formation to total defect area was 0.32% in control group, 1.10% in experimental group. At 4 weeks, the proportion of new bone formation to total defect area was 6.86% in control, and 13.75% in experimental. At 6 and 8 weeks, no obvious difference was found between the two groups but newly formed bone in test groups were slightly more than that in control groups. In conclusion, negatively charged membranes showed more newly bone tissue than noncharged membranes at an early healing period. Although the number of samples was small, this study showed that the combination of negatively electrical stimulation and P1FE membrane may be of value in long bone healing.

• Archives of Plastic Surgery
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• 제37권5호
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• pp.671-675
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• 2010

Purpose: In order to maintain corrected nasal tip projection, strong support is important. Authors used calvarial bone graft method for this purpose. Patients were followed up about permanency of the bone graft for a long time. Methods: From 1995 to 1998, author performed calvarial bone graft on 30 adult patients with secondary cleft lip and nose deformity. Patients were observed for 34 months. There were no specific complications, and results were satisfactory. We could confirm the permanence of the calvarial bone graft in 3 patients by photography and radiologic studies for 10 years follow-up. Results: None of the patients showed size change or displacement. But the portion of graft facing the tip was absorbed resulting in loss of tip projection and short nose in two patients. One patient had fracture on the middle of the graft. This caused depression from lower portion of the dorsum to the tip. Conclusion: Despite of autogenous grafts such as calvarial bone, absorption of the bone may occur when compressed with tension for a long period. And the graft in the nasal tip not having any contact with the nasal bone may cause absorption of the graft.

• Nutrition Research and Practice
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• 제8권4호
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• pp.360-367
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• 2014

BACKGROUND/OBJECTIVES: The aim of this research was to study the different long term effects of consumption of dietary oil sources with varying omega-6/omega-3 (${\omega}-6/{\omega}-3$) polyunsaturated fatty acids (PUFAs) ratios on bone marrow fatty acid level, ex vivo prostaglandin $E_2$ ($PGE_2$) release, and mineral content of bone in rabbits. MATERIALS/METHODS: For this purpose, weaning and female New Zealand white rabbits were purchased and randomly divided into five groups and offered ad libitum diets containing 70 g/kg of added oil for 100 days. The dietary lipid treatments were formulated to provide the following ratios of ${\omega}-6/{\omega}-3$ fatty acids: 8.68 soy bean oil (SBO control), 21.75 sesame oil (SO), 0.39 fish oil (FO), 0.63 algae oil (DHA), and 0.68 algae oils (DHA/ARA). DHA and ARA are two types of marine microalgae of the genus Crypthecodinium cohnii. RESULTS: The dietary treatments had significant effects on the bone marrow fatty acids of rabbits. Rabbits fed the FO diet, containing the highest ${\omega}-3$ PUFA concentration, and those fed the SBO diet showed the highest ${\omega}-6$ PUFA. On the other hand, a positive correlation was observed between Ex vivo $PGE_2$ level and the ${\omega}-6/{\omega}-3$ dietary ratio. Significant effects of dietary treatment on femur Ca, P, Mg, and Zn contents were observed in both genders. CONCLUSIONS: Findings of the current study clearly demonstrated that dietary PUFA, particularly ${\omega}-6/{\omega}-3$ and ARA/EPA ratios are important factors in determining bone marrow fatty acid profile, and this in turn determines the capacity of bone for synthesis of $PGE_2$, thereby reducing bone resorption and improving bone mass during growth.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 한국정밀공학회 2006년도 춘계학술대회 논문집
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• pp.177-178
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• 2006

Many authors issued the feature-preserving averaging technique according to positioning and scaling process using landmarks, which represent the geometric characteristics of three dimensional surface models. Such a technique should be done by manual procedure, choosing and marking the landmarks on each bone surface before averaging process. In this study, we produced another averaging technique without having to use such manual procedure, and made averaging models from three dimensional surface data that were reconstructed from computerized tomography images of Digital Korean Project. The bone models were subjected to orthogonal coordinator system. These models were transformed to coincide mass center and to align principal axis. Then, bone models were scaled according to average length data of sample bone models on all axis(x, y, z). After establishing voxellar hexahedron space which contain all sample bone models, we counted the number of overlapping for each voxel. We generated the three dimensional average surface by displaying the yokels that have more overlapping number than boundary number. The boundary number was decided when the average volume of each bone equal to the volume of bone that would be averaged. Using this technique, we can make a feature-preserving averaging volume of bones.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 한국정밀공학회 2011년도 춘계학술대회 논문집
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• pp.967-968
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• 2011

• The Korean Journal of Nuclear Medicine
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• 제33권4호
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• pp.341-351
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• 1999

Biochemical markers of bone turnover has received increasing attention over the past few years, because of the need for sensitive and specific tool in the clinical investigation of osteoporosis. Bone markers should be unique to bone, reflect changes of bone loss, and should be correlated with radiocalcium kinetics, histomorphometry, or changes in bone mass. The markers also should be useful in monitoring treatment efficacy. Although no bone marker has been established to meet all these criteria, currently osteocalcin and pyridinium crosslinks are the most efficient markers to assess the level of bone turnover in the menopausal and senile osteoporosis. Recently, N-terminal telopeptide (NTX), C-terminal telopeptide (CTX) and bone specific alkaline phosphatase are considered as new valid markers of bone turnover. Recent data suggest that CTX and free deoxypyridinoline could predict the subsequent risk of hiP fracture of elderly women. Treatment of postmenopausal women with estrogen, calcitonin and bisphosphonates demonstrated rapid decrease of the levels of bone markers that correlated with the long-term increase of bone mass. Factors such as circadian rhythms, diet, age, sex, bone mass and renal function affect the results of biochemical markers and should be appropriately adjusted whenever possible. Each biochemical markers of bone turnover may have its own specific advantages and limitations. Recent advances in research will provide more sensitive and specific assays.

• Journal of Korean Foot and Ankle Society
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• 제7권2호
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• pp.279-282
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• 2003

Most simple bone cysts are found in the metaphysis of the long bone, such as proximal humerus or proximal femur. Appropriate treatment is aspiration of the cyst followed by instillation of methylprednisolone or curettage with bone graft. We experienced 1 case of the simple bone cyst of the metatarsal bone. This case was treated by curettage and inserting allograft into the defect.

• CELLMED
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• 제9권4호
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• pp.7.1-7.4
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• 2019

A cuttlefish bone is not a bone, but the internal shell of the Cuttlefish/ sepia officinalis, a small, squid-like cephalopod of phylum molusca, an animals of the order Sepiida. Cuttlefish bone comprises up to 90 percent of its content of calcium carbonate with the abundance of different bioinorganic elements such as magnesium, strontium, iron, even trace amounts of copper, zinc, aragonite and ${\beta}$-chitin which makes it extremely valuable and worthwhile to be used for biomedical research. Unani system of medicine has been using cuttlefish bone under the name of 'kafe dariya' for the treatment various disorders and ailments since centuries. Unani scholars were well aware of the valuable medical and cosmetologically aspect of cuttlefish bone. However, the drug has been forgotten for its beneficial effect and went deep away from the scientific researches. The purpose of the present review is to highlight and revive the data on cuttlefish and cuttlefish bone for its morphology, composition, types, pharmacological actions, temperament, therapeutic dosage, contraindications, correctives, alternatives and therapeutic uses with special reference of Unani medicine to attain its the beneficial features in biomedical sciences.