• 동의신경정신과학회지
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• 제9권2호
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• pp.19-35
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• 1998

Some oriental medicine turned out to have a significant clinical effect on the cure for dementia. Therefore, thorough scientific tests for physiological effect of oriental medicne are needed. This study is aimed at doing experimental studies on the effects of two medicines, Jowiseungcheongtang and hyungbangjihwangtang, on the cure for dementia.For the demonstration of the effect of the two medicines on aged rats, we perfomed a radial arm medicines on aged rats, water maze task, known for their proper learning paradigm for behavior.Previous studies on aging and dementia show that aged rats displayed significant impariments in the learning of the radial arm maze task compared with younger rats. As in experiment 1, we found that the learning of the radial arm maze task compared with younger rats. As in experiment 1, we found that the learning deficits aged rats exhibit in radial arm maze task were improved with the application of each medicine. The resutls suggest that these two medicine can be effective to patients whose working or shortterm memory is impaired. In experiment 2 we studied the effect of the two medicines on the deficit of the aged rats with the Morris water maze task known for measuring long-tern memory. We did not find significant results between the performance of the ages rats and the younger ones. Considered the different results previous studies have reported, more thorough studies are needed to investigate the effect of the medicines on long-term memory.In conclusion, the results we found in experiment 1 and 2 suggest that Jowisengcheongtang and hyungbangjihwangtang can have useful effects for the cure of age-related memory (especially for short-term memory)deficits. Recent interests in dementia urges researchers concerned to explore the effect of oriental medicine on the disease. As there have been relatively few behavioral or scientific studies on dementia using oriental medicine to date, further studies are expected are expected to continue to elucidate 'what the wisdom of the oriental medicine tells about dementia'.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제17권1호
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• pp.216-238
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• 2023

In intelligent transportation systems, traffic management is an important task. The accurate forecasting of traffic characteristics like flow, congestion, and density is still active research because of the non-linear nature and uncertainty of the spatiotemporal data. Inclement weather, such as rain and snow, and other special events such as holidays, accidents, and road closures have a significant impact on driving and the average speed of vehicles on the road, which lowers traffic capacity and causes congestion in a widespread manner. This work designs a model for multivariate short-term traffic congestion prediction using SLSTM_AE-BiLSTM. The proposed design consists of a Bidirectional Long Short Term Memory(BiLSTM) network to predict traffic flow value and a Convolutional Neural network (CNN) model for detecting the congestion status. This model uses spatial static temporal dynamic data. The stacked Long Short Term Memory Autoencoder (SLSTM AE) is used to encode the weather features into a reduced and more informative feature space. BiLSTM model is used to capture the features from the past and present traffic data simultaneously and also to identify the long-term dependencies. It uses the traffic data and encoded weather data to perform the traffic flow prediction. The CNN model is used to predict the recurring congestion status based on the predicted traffic flow value at a particular urban traffic network. In this work, a publicly available Caltrans PEMS dataset with traffic parameters is used. The proposed model generates the congestion prediction with an accuracy rate of 92.74% which is slightly better when compared with other deep learning models for congestion prediction.

• 산업경영시스템학회지
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• 제24권63호
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• pp.13-21
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• 2001

The present study compared the two experimental methods on inquiring the image structure of odors: Presenting a stimulus is one, and not presenting a stimulus is the other. For experiment one, five odors were presented, and the subjects were instructed to evaluate the odors on 7-point scale for each of the 25 adjectives. For experiment two, no odor was presented, and the subjects were instructed to perform the pair-wise comparisons for the each pair of two adjectives on their similarities on 7-point scale. The data from the two experiments were analysed and compared using MDS(Multi-Dimensional Scaling), Correlation, Cluster Analysis. The results showed that there was no structural differences between two experimental methods in term of the Image structure of odors. But, minor disparity was found between two methods in terms of density of distribution of the adjectives. It was construed that the difference came from the difference of the memory that was used for each of the experiments; that is, short term memory for experiment one and long-term memory for experiment two.

• 한국디자인학회:학술대회논문집
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• 한국디자인학회 2004년도 춘계 학술발표대회 논문집
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• pp.304-305
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• 2004

• 응용통계연구
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• 제32권1호
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• pp.69-81
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• 2019

본 논문에서는 딥러닝을 이용한 이변량 장기종속시계열(long-range dependent time series) 예측을 고려하였다. 시계열 데이터 예측에 적합한 LSTM(long short-term memory) 네트워크를 이용하여 이변량 장기종속시계열을 예측하고 이를 이변량 FARIMA(fractional ARIMA) 모형인 FIVARMA 모형과 VARFIMA 모형과의 예측 성능을 실증 자료 분석을 통해 비교하였다. 실증 자료로는 기능적 자기공명 영상(fMRI) 및 일일 실현 변동성(daily realized volatility) 자료를 이용하였으며 표본외 예측(out-of sample forecasting) 오차 비교를 통해 예측 성능을 측정하였다. 그 결과, FIVARMA 모형과 VARFIMA 모형의 예측값에는 미묘한 차이가 존재하며, LSTM 네트워크의 경우 초매개변수 선택으로 복잡해 보이지만 계산적으로 더 안정되면서 예측 성능도 모수적 장기종속시계열과 뒤지지 않은 좋은 예측 성능을 보였다.

• International Journal of Industrial Entomology and Biomaterials
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• 제15권1호
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• pp.39-45
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• 2007

Extracts of adult worker bodies of Vespa simillima in 2 % NaCl or acidified methanol were administered orally to mice for 70 days. Following this period, memory at one-day and one-month periods, and the effects on scopolamine-induced amnesia were examined using a step-through passive avoidance task. Changes in MK-801-induced disability after 8 days of training, and in memory one month after the trial were also assessed. Mice treated with the 2% NaCl extract showed significant improvement in memory in the behavioral tests one month after the trial, whereas mice receiving the extract in acidified methanol, did not differ from the controls in any trial. The results inidicate that Vespa simillima contains substances acting favorably on the cerebral functions of mammals.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2005년도 International Meeting on Information Displayvol.I
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• pp.567-570
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• 2005

Most researches on monostable LCD and bistable LCD have separately been carried out. We introduce a novel liquid crystal display mode which can be operated as both memory mode and dynamic mode. The novel LCD mode has not only a long term memory time of memory mode but also a fast response time of dynamic mode. We describe switching characteristics of dual mode. Electro-optical characteristics of memory mode and dynamic mode are unique and show the possibility of device application.

• Advances in Traditional Medicine
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• 제7권2호
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• pp.182-190
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• 2007

Alzheimer's disease is a neurodegenerative disorder associated with a decline in cognitive abilities. Dementia is one of the aged related mental problems and a characteristic symptom of Alzheimer's disease. Nootropic agents like piracetam and cholinesterase inhibitors like $Donepezil^{\circledR}$ are used in situations where there is organic disorder in learning abilities, but the resulting side-effects associated with these agents have limited their utility. Foeniculum (F.) vulgare Linn. is widely used in Indian traditional systems of medicines and also as a house remedy for nervous debility. The present work was undertaken to assess the potential of F. vulgare as a nootropic and anti-cholinesterase agent in mice. Exteroceptive behavioral models such as Elevated plus maze and Passive avoidance paradigm were employed to assess short term and long term memory in mice. To delineate the possible mechanism through which F. vulgare elicits the anti-amnesic effects, its influence on central cholinergic activity was studied by estimating the whole brain acetylcholinesterase activity. Pretreatment of methanolic extract of fruits of F. vulgare Linn. for 8 successive days, ameliorated the amnesic effect of scopolamine (0.4 mg/kg) and aging induced memory deficits in mice. F. vulgare extract significantly decreased transfer latencies of young mice and aged mice, increased step down latency and exhibited significant anti-acetyl cholinesterase effects, when compared to piracetam, scopolamine and control groups of mice. F. vulgare might prove to be a useful memory restorative agent in the treatment of dementia seen in the elderly.

• 인지과학
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• 제30권4호
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• pp.239-268
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• 2019

영상기억은 시각기억 처리 과정의 최초 저장 기제로서 오랫동안 이론적인 타당성을 인정받아왔다. 그러나 최근 관심이 대폭 증가한 시각단기기억과 시각장기기억에 비해 영상기억에 대한 연구자들의 관심은 상대적으로 부족했던 것이 사실이다. 이러한 관심의 부족은 영상기억 및 시각지속 현상에 대한 이론 및 방법론적 이해의 결여가 그 원인인 것으로 짐작된다. 본 연구는 영상기억 및 시각지속 현상에 대한 이론적 배경과 경험적 연구 사례를 개관해 영상기억에 대한 상세한 이해를 도모하였다. 더 나아가 영상기억의 타당성에 대한 현상학적, 생태학적 비판들의 핵심 내용들을 토대로 향후 영상기억 연구의 방향을 가늠하는데 목적을 두었다.

• 동의생리병리학회지
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• 제20권2호
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• pp.471-476
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• 2006

Chongmyung-tang(CMT, 聰明湯), oriental herbal medicine which consists of Polygaglae Radix(遠志), Acori Graminei Rhizoma(石菖蒲) and Hoelen(白茯神) has effect on amnesia, dementia. In order to evaluate effect of CMT on memory and learning in mice, CMT extract was used for studies. This paper describes the effects of CMT extract on memory and learning processes by using the passive and active avoidance performance tests, novel object recognition task and water maze task. The CMT extract ameliorated the memory retrieval deficit induced by ethanol in the passive avoidance responses but did not affect ambulatory activity of normal mice. These results suggest that CMT has an ameliorating effect on memory retrieval impairment. CMT extract decreased spontaneous motor activity(SMA) in the latter sessions of memory registration in active avoidance responses. These results suggest that CMT has partly transquilizing or antianxiety effects. In novel object recognition task to measure visual recognition memory, CMT-administered mice enhanced in long term memory for 1-3 days. In water maze task to measure spatial learning, which requires the activation of NMDA receptors in the hippocampus, spatial learning in CMT-administered mice was faster than in wild-type mice. These results suggest that CMT enhances memory and activates NMDA receptors.